Demographic and clinical predictors of health-related quality of life among people with type 2 diabetes mellitus living in northern Thailand : A cross-sectional study

Journal article


Khunkaew, Saneh, Fernandez, Ritin and Sim, Jenny. (2019). Demographic and clinical predictors of health-related quality of life among people with type 2 diabetes mellitus living in northern Thailand : A cross-sectional study. Health and Quality of Life Outcomes. 17(1), p. Article 177. https://doi.org/10.1186/s12955-019-1246-2
AuthorsKhunkaew, Saneh, Fernandez, Ritin and Sim, Jenny
Abstract

Background
Type 2 Diabetes Mellitus (T2DM) is a chronic disease which is growing global health problems. However, research on such prediction of health-related quality of life (HRQOL) in Thailand is limited, in particular on the demographic and clinical characteristic in each HRQOL domains. Therefore, the aim of the present study was to determine the demographic and clinical predictors of health-related quality of life among people with type 2 diabetes mellitus (T2DM) in Northern Thailand.

Methods
A cross-sectional study of people with T2DM at a large teaching hospital in Northern Thailand was conducted. The HRQOL was evaluated using the Thai version of Diabetes-39. Descriptive analysis was used to summarize the demographic and HRQOL scores. Multiple regression analysis was used to determine the predictors of overall HRQOL and the predictors of each D-39 dimension.

Results
A total of 502 people with T2DM were recruited. Forty-one were identified as having diabetic foot ulcers. The mean score for perception of overall HRQOL was 61.18 (SD 18.74). Scores in the D-39 questionnaire showed a poor HRQOL among people with T2DM. The predictors of demographic and clinical characteristics of people with T2DM were calculated for overall HRQOL and all six domains.

Conclusion
These results demonstrate that people with T2DM have a poor HRQOL. The presence of diabetic foot ulcers and smoking status were identified as significant predictors of low HRQOL in the domains relating to diabetes control, social burden and energy and mobility presence of obesity, receiving insulin injection or a combination of insulin and oral medication were predictors of poor HRQOL in the domain of other health problems and diabetes complications. These findings allow for a nursing care plan for diabetes management to achieve optimal glycaemic control and improve their HRQOL.

Keywordshealth-related quality of life; diabetes mellitus; diabetic foot ulcer; Thailand; predictor and nursing
Year2019
JournalHealth and Quality of Life Outcomes
Journal citation17 (1), p. Article 177
PublisherBiomed Central Ltd
ISSN1477-7525
Digital Object Identifier (DOI)https://doi.org/10.1186/s12955-019-1246-2
PubMed ID31796044
Scopus EID2-s2.0-85075930261
PubMed Central IDPMC6889205
Open accessPublished as ‘gold’ (paid) open access
Page range1-9
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online03 Dec 2019
Publication process dates
Accepted15 Nov 2019
Deposited23 Apr 2025
Additional information

© The Author(s). 2019.

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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