Clinical exercise interventions in prostate cancer patients-a systematic review of randomized controlled trials

Journal article


Baumann, Freerk T., Zopf, Eva M. and Bloch, Wilhelm. (2012) Clinical exercise interventions in prostate cancer patients-a systematic review of randomized controlled trials. Supportive Care in Cancer. 20(2), pp. 221 - 233. https://doi.org/10.1007/s00520-011-1271-0
AuthorsBaumann, Freerk T., Zopf, Eva M. and Bloch, Wilhelm
Abstract

Introduction: Urinary incontinence, erectile dysfunction, fatigue as well as fears and depression rank among the most common complaints in patients with prostate cancer, resulting in a reduced participation in daily life and social isolation. Consequently, the quality of life of prostate cancer patients is strongly affected in a negative way. Numerous studies focusing on physical exercise interventions in prostate cancers patients demonstrate positive physiological and psychological effects. Our objective was to evaluate the evidence of randomized controlled studies which examined exercise during medical treatment and in the aftercare of a prostate cancer disease. Methods: Twenty-five randomized controlled trials regarding physical activities in patients with prostate cancer were obtained by systematic literature research ( Medpilot ). Twenty-one studies examined clinical exercise interventions during the phase of medical treatment ( irradiation, pre- and/or post-op, androgen deprivation therapy ) and four studies during the aftercare. In order to evaluate the evidence of the included studies, the evaluation system of the Oxford Centre for Evidence-Based Medicine was used. Within this systematic review, we differentiated between “supervised clinical exercise” and “non-supervised clinical exercise.” Results and discussion: Current data suggest that incontinence, fitness, fatigue, body constitution, and also quality of life can be improved by clinical exercise in patients during and after prostate cancer. Studies were mostly ranked evidence level “2b.” Only four studies, all conducted during medical treatment, reached the level “1b.” It seems to be that “supervised exercise” is more effective than “non-supervised exercise.” For future research, further randomized controlled trials with high methodological quality need to be conducted in order to establish evidence-based recommendations particularly for prostate cancer patients.

Keywordsprostate cancer; clinical exercise; cancer; rehabilitation; physical activity
Year2012
JournalSupportive Care in Cancer
Journal citation20 (2), pp. 221 - 233
PublisherSpringer Verlag
ISSN0941-4355
Digital Object Identifier (DOI)https://doi.org/10.1007/s00520-011-1271-0
Scopus EID2-s2.0-84855205695
Page range221 - 233
Research GroupInstitute for Health and Ageing
Publisher's version
File Access Level
Controlled
Place of publicationGermany
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