Lower limb progressive resistance training improves leg strength but not gait speed or balance in Parkinson's disease: A systematic review and meta-analysis

Journal article


Tillman, Alex Tillman, Muthalib, Makii, Hendy, Ashlee M., Johnson, Liam G., Rantalainen, Timo, Kidgell, Dawson J., Enticott, Peter G. and Teo, Wei-Peng. (2015). Lower limb progressive resistance training improves leg strength but not gait speed or balance in Parkinson's disease: A systematic review and meta-analysis. Frontiers in Aging Neuroscience. 7, pp. 1 - 10. https://doi.org/10.3389/fnagi.2015.00040
AuthorsTillman, Alex Tillman, Muthalib, Makii, Hendy, Ashlee M., Johnson, Liam G., Rantalainen, Timo, Kidgell, Dawson J., Enticott, Peter G. and Teo, Wei-Peng
Abstract

The use of progressive resistance training ( PRT ) to improve gait and balance in people with Parkinson’s disease ( PD ) is an emerging area of interest. However, the main effects of PRT on lower limb functions such as gait, balance, and leg strength in people with PD remain unclear. Therefore, the aim of the meta-analysis is to evaluate the evidence surrounding the use of PRT to improve gait and balance in people with PD. Five electronic databases, from inception to December 2014, were searched to identify the relevant studies. Data extraction was performed by two independent reviewers and methodological quality was assessed using the PEDro scale. Standardized mean differences ( SMD ) and 95% confidence intervals ( CIs ) of fixed and random effects models were used to calculate the effect sizes between experimental and control groups and I2 statistics were used to determine levels of heterogeneity. In total, seven studies were identified consisting of 172 participants ( experimental n = 84; control n = 88 ). The pooled results showed a moderate but significant effect of PRT on leg strength ( SMD 1.42, 95% CI 0.464–2.376 ); however, no significant effects were observed for gait speed ( SMD 0.418, 95% CI −0.219 to 1.055 ). No significant effects were observed for balance measures included in this review. In conclusion, our results showed no discernable effect of PRT on gait and balance measures, although this is likely due to the lack of studies available. It may be suggested that PRT be performed in conjunction with balance or task-specific functional training to elicit greater lower limb functional benefits in people with PD.

KeywordsParkinson’s disease; progressive resistance training; leg strength; gait speed; balance
Year2015
JournalFrontiers in Aging Neuroscience
Journal citation7, pp. 1 - 10
PublisherFrontiers Research Foundation
ISSN1663-4365
Digital Object Identifier (DOI)https://doi.org/10.3389/fnagi.2015.00040
Scopus EID2-s2.0-84926318560
Open accessOpen access
Page range1 - 10
Research GroupSports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre
Publisher's version
Additional information

© 2015 Tillman, Muthalib, Hendy, Johnson, Rantalainen, Kidgell, Enticott and Teo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Place of publicationSwitzerland
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