Mary MacKillop Institute for Health Research


TypeDepartment
FacultyFaculty of Health Sciences

Latest research outputs

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2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines JACC
Donna K. Arnett, Roger S Blumenthal, Michelle A Albert, Andrew B Buroker, Zachary D Goldberger, Ellen G Hahn, Cheryl D Himmelfarb, Amit Khera, Donald M. Lloyd-Jones, J William McEvoy, Erin D Michos, Michael D Miedema, Daniel Munoz, Sidney C. Smith, Salim S Virani, Kim A Williams, Joseph Yeboah, Boback Ziaeian, Patrick T. O'Gara, ... Duminda Wijeysundera. (2019). 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines JACC. Journal of the American College of Cardiology. 74(10), pp. 177-232. https://doi.org/10.1016/j.jacc.2019.03.010

Journal article

Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome
Bustamante, M., Hernandez-Ferrer, C., Tewari, A., Sarria, Y., Harrison, G. I., Puigdecanet, E., Nonell, L., Kang, W., Friedländer, M. R., Estivill, X., González, J. R., Nieuwenhuijsen, M. and Young, A. R.. (2019). Dose and time effects of solar-simulated ultraviolet radiation on the in vivo human skin transcriptome. British Journal of Dermatology. 182(6), pp. 1458-1468. https://doi.org/10.1111/bjd.18527

Journal article

The early-life exposome: Description and patterns in six European countries
Tamayo-Uria, Ibon, Maitre, Lea, Thomsen, Cathrine, Nieuwenhuijsen, Mark J., Chatzi, Leda, Siroux, Valerie, Aasvang, Gunn Marit, Agier, Lydiane, Andrusaityte, Sandra, Casas, Maribel, Castro, Montserrat de, Dedele, Audrius, Haug, Line Smastuen, Heude, Barbara, Grazuleviciene, Regina, Gutzkow, Kristine B., Krog, Norun Hjertager, Mason, Dan, McEachan, Rosemary R. C., ... Basagaña, Xavier. (2019). The early-life exposome: Description and patterns in six European countries. Environment International. 123, pp. 189 - 200. https://doi.org/10.1016/j.envint.2018.11.067

Journal article

Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry
Nelson, Marin E., Parker, Benjamin L., Burchfield, James G., Hoffman, Nolan J., Needham, Elise J., Cooke, Kristen C., Naim, Timur, Sylow, Lykke, Ling, Naomi X. Y., Francis, Deanne, Norris, Dougall M., Chaudhuri, Rima, Oakhill, Jonathan S., Richter, Erik A., Lynch, Gordon S., Stockli, Jacqueline and James, David E.. (2019). Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry. The EMBO Journal. 38(24), pp. 1 - 20. https://doi.org/10.15252/embj.2019102578

Journal article

Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review
Bauer, Jurgen M., Cruz-Jentoft, Alfonso J., Fielding, Roger A., Kanis, John A., Reginster, Jean-Yves, Bruyere, Olivier, Cesari, Matteo, Chapurlat, Roland, Al-Daghri, Nasser, Dennison, Elaine M., Kaufman, Jean-Marc, Landi, Francesco, Laslop, Andrea, Locquet, Medea, Maggi, Stefania, McCloskey, Eugene, Perna, Simone, Rizzoli, Rene, Rolland, Yves, ... Cooper, Cyrus. (2019). Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review. Calcified Tissue International. 105, pp. 109 - 124. https://doi.org/10.1007/s00223-019-00561-w

Journal article

Correlates of walking for travel in seven european cities: The PASTA Project
Gascon, Mireia, Gotschi, Thomas, Nazelle, Audrey de, Gracia, Esther, Ambros, Albert, Marquez, Sandra, Marquet, Oriol, Avila-Palencia, Ione, Brand, Christian, Iacorossi, Francesco, Raser, Elisabeth, Gaupp-Berghausen, Mailin, Dons, Evi, Laeremans, Michelle, Kahlmeier, Sonja, Sanchez, Julian, Gerike, Regine, Anaya-Boig, Esther, Panis, Luc Int and Nieuwenhuijsen, M.. (2019). Correlates of walking for travel in seven european cities: The PASTA Project. Environmental Health Perspectives. 127(9), pp. 1 - 13. https://doi.org/10.1289/EHP4603

Journal article

2018 AHA/ACC guideline for the management of adults with congenital heart disease [Clinical Practice Guideline]
Stout, Karen K., Daniels, Curt J., Aboulhosn, Jamil A., Bozkurt, Biykem, Broberg, Craig S., Colman, Jack M., Crumb, Stephen R., Dearani, Joseph A., Fuller, Stephanie, Gurvitz, Michelle Z., Khairy, Paul, Landzberg, Michael J., Saidi, Arwa, Valente, Anne Marie, Van Hare, George F. and Riegel, Barbara. (2019). 2018 AHA/ACC guideline for the management of adults with congenital heart disease [Clinical Practice Guideline]. Journal of the American College of Cardiology. 73(12), pp. 81 - 192. https://doi.org/10.1016/j.jacc.2018.08.1029

Journal article

Between-meal sucrose-sweetened beverage consumption impairs glycaemia and lipid metabolism during prolonged sitting : A randomized controlled trial
Varsamis, Pia, Formosa, Melissa F., Larsen, Robyn N., Reddy-Luthmoodoo, Medini, Jennings, Garry L., Cohen, Neale D., Grace, Megan S., Hawley, John A., Devlin, Brooke L., Owen, Neville, Dunstan, David W., Dempsey, Paddy C. and Kingwell, Bronwyn A.. (2019). Between-meal sucrose-sweetened beverage consumption impairs glycaemia and lipid metabolism during prolonged sitting : A randomized controlled trial. Clinical Nutrition. 38(4), pp. 1536-1543. https://doi.org/10.1016/j.clnu.2018.08.021

Journal article

Characterizing the plasma metabolome during 14 days of live-high, train-low simulated altitude: A metabolomic approach
Lawler, Nathan G., Abbiss, Chris R., Gummer, Joel P. A., Broadhurst, David I., Govus, Andrew D., Fairchild, Timothy J., Thompson, Kevin G., Garvican-Lewis, Laura A., Gore, Christopher J., Maker, Garth L., Trengove, Robert D. and Peiffer, Jeremiah J.. (2019). Characterizing the plasma metabolome during 14 days of live-high, train-low simulated altitude: A metabolomic approach. Experimental Physiology. 104(1), pp. 81 - 92. https://doi.org/10.1113/EP087159

Journal article

Heart failure with reduced ejection fraction: Comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas
Dewan, Pooja, Jhund, Pardeep S., Shen, Li, Petrie, Mark C., Abraham, William T., Ali, M. Atif, Chen, -Huan Chen, Desai, Akshay S., Dickstein, Kenneth, Huang, Jun, Kiatchoosakun, Songsak, Kim, Kee-Sik, Køber, Lars, Lai, Wen-Ter, Liao, Yuhua, Mogensen, Ulrik M., Oh, Byung-Hee, Packer, Milton, Rouleau, Jean L., ... McMurray, John J. V.. (2019). Heart failure with reduced ejection fraction: Comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure. 21(5), pp. 577 - 587. https://doi.org/10.1002/ejhf.1347

Journal article

Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: A double-blind, randomized trial
Fuchs, Cas J., Hermans, Wesley J. H., Holwerda, Andrew M., Smeets, Joey S. J., Senden, Joan M., van Kranenburg, Janneau, Gijsen, Annemie P., Wodzig, Will K. W. H., Schierbeek, Henk, Verdijk, Lex B. and van Loon, Luc J. C.. (2019). Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: A double-blind, randomized trial. American Journal of Clinical Nutrition. 110(4), pp. 862 - 872. https://doi.org/10.1093/ajcn/nqz120

Journal article

Echocardiographic features of patients with heart failure and preserved left ventricular ejection fraction
Shah, Amil M., Cikes, Maja, Prasad, Narayana, Li, Guichu, Getchevski, Stoyan, Claggett, Brian L., Rizkala, Adel R., Lukashevich, Ilya, O'Meara, Eileen, Ryan, John J., Shah, Sanjiv J., Mullens, Wilfred, Zile, Michael R., Lam, Carolyn S. P., McMurray, John J. V. and Solomon, Scott D.. (2019). Echocardiographic features of patients with heart failure and preserved left ventricular ejection fraction. Journal of the American College of Cardiology. 74(23), pp. 2858 - 2873. https://doi.org/10.1016/j.jacc.2019.09.063

Journal article

The cost of osteoporosis, osteopenia, and associated fractures in Australia in 2017
Tatangelo, Gemma, Watts, Jennifer J., Lim, Karen, Connaughton, Catherine, Abimanyi-Ochom, Julie, Borgström, Fredrik, Nicholson, Geoff C., Shore-Lorenti, Catherine, Stuart, Amanda L., Iuliano-Burns, Sandra, Seeman, Ego, Prince, Richard L., March, Lyn, Cross, Marita, Winzenberg, Tania, Laslett, Laura L., Duque, Gustavo, Ebeling, Peter R. and Sanders, Kerrie M.. (2019). The cost of osteoporosis, osteopenia, and associated fractures in Australia in 2017. Journal of Bone and Mineral Research. 34(4), pp. 616 - 625. https://doi.org/10.1002/jbmr.3640

Journal article

Validating and shortening the environmental assessment of public recreation spaces observational measure
Geremia, Carrie M., Cain, Kelli L., Conway, Terry L., Sallis, James F. and Saelens, Brian E.. (2019). Validating and shortening the environmental assessment of public recreation spaces observational measure. Journal of Physical Activity and Health. 16(1), pp. 68 - 75. https://doi.org/10.1123/jpah.2018-0142

Journal article

Long-term impacts of prenatal and infant exposure to fine particulate matter on wheezing and asthma
Shao, Jingyi, Wheeler, Amanda J., Zosky, Graeme R. and Johnston, Fay H.. (2019). Long-term impacts of prenatal and infant exposure to fine particulate matter on wheezing and asthma. Environmental Epidemiology. 3(2), pp. 1 - 7. https://doi.org/10.1097/EE9.0000000000000042

Journal article

Gut bacteria are critical for optimal muscle function: A potential link with glucose homeostasis
Nay, Kevin, Jollet, Maxence, Goustard, Benedicte, Baati, Narjes, Vernus, Barbara, Pontones, Maria, Lefeuvre-Orfila, Luz, Bendavid, Claude, Rué, Olivier, Mariadassou, Mahendra, Bonnieu, Anne, Ollendorff, Vincent, Lepage, Patricia, Derbré, Frédéric and Koechlin-Ramonatxo, Christelle. (2019). Gut bacteria are critical for optimal muscle function: A potential link with glucose homeostasis. American Journal of Physiology: Endocrinology and Metabolism. 317(1), pp. 158 - 171. https://doi.org/10.1152/ajpendo.00521.2018

Journal article

Objectively measured access to recreational destinations and leisure-time physical activity: Associations and demographic moderators in a six-country study
Gidlow, Christopher, Cerin, Ester, Sugiyama, Takemi, Adams, Marc A., Mitas, Josef, Akram, Muhammad, Reis, Rodrigo S., Davey, Rachel, Troelsen, Jens, Schofield, Grant and Sallis, James F.. (2019). Objectively measured access to recreational destinations and leisure-time physical activity: Associations and demographic moderators in a six-country study. Health and Place. 59, p. Article 102196. https://doi.org/10.1016/j.healthplace.2019.102196

Journal article

Distances walked to and from local destinations: Age-related variations and implications for determining buffer sizes
Sugiyama, Takemi, Kubota, Akio, Sugiyama, Masaaki, Cole, Rachel and Owen, Neville. (2019). Distances walked to and from local destinations: Age-related variations and implications for determining buffer sizes. Journal of Transport and Health. 15, pp. 1 - 7. https://doi.org/10.1016/j.jth.2019.100621

Journal article

Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults
Gratza, S. K., Chocano-Bedoya, Patricia O., Orav, E. J., Fischbacher, M., Freystätter, G., Theiler, Robert, Egli, Andreas, Kressig, R. W., Kanis, John A. and Bischoff-Ferrari, Heike A.. (2019). Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults. Osteoporosis International. 30, pp. 2205 - 2215. https://doi.org/10.1007/s00198-019-05110-7

Journal article

Exploration of gray matter correlates of cognitive training benefit in adolescents with chronic traumatic brain injury
Vander Linden, Catharine, Verhelst, Helena, Deschepper, Ellen, Vingerhoets, Guy, Deblaere, Karel and Caeyenberghs, Karen. (2019). Exploration of gray matter correlates of cognitive training benefit in adolescents with chronic traumatic brain injury. NeuroImage: Clinical. 23, pp. 1 - 10. https://doi.org/10.1016/j.nicl.2019.101827

Journal article

A framework for periodized nutrition for athletics
Stellingwerff, Trent, Morton, James P. and Burke, Louise M.. (2019). A framework for periodized nutrition for athletics. International Journal of Sport Nutrition and Exercise Metabolism. 29(2), pp. 141-151. https://doi.org/10.1123/ijsnem.2018-0305

Journal article

Measuring time in the office using bluetooth sensors: Feasibility and validity considerations
Clark, Bronwyn K., Hadgraft, Nyssa T., Sugiyama, Takemi and Winkler, Elisabeth A. H.. (2019). Measuring time in the office using bluetooth sensors: Feasibility and validity considerations. Journal for the Measurement of Physical Behaviour. 2(1), pp. 36 - 44. https://doi.org/10.1123/jmpb.2018-0046

Journal article

Prognostic implications of changes in amino-terminal pro–b-type natriuretic peptide in acute decompensated heart failure: Insights From ASCEND-HF
Grodin, Justin L., Liebo, Max J., Butler, Javed, Metra, Marco, Felker, G. Michael, Hernandez, Adrian F., Voors, Adriaan A., McMurray, John J. V., Armstrong, Paul W., O'Connor, Christopher M., Starling, Randall C., Troughton, Richard W. and Tang, W. H. Wilson. (2019). Prognostic implications of changes in amino-terminal pro–b-type natriuretic peptide in acute decompensated heart failure: Insights From ASCEND-HF. Journal of Cardiac Failure. 25(9), pp. 703 - 711. https://doi.org/10.1016/j.cardfail.2019.04.002

Journal article

Oral supplementation of specific collagen peptides combined with calf-strengthening exercises enhances function and reduces pain in achilles tendinopathy patients
Praet, Stephan F. E., Purdam, Craig R., Welvaert, Marijke, Vlahovich, Nicole, Lovell, Gregg, Burke, Louise M., Gaida, Jamie E., Manzanero, Silvia, Hughes, David and Waddington, Gordon. (2019). Oral supplementation of specific collagen peptides combined with calf-strengthening exercises enhances function and reduces pain in achilles tendinopathy patients. Nutrients. 11(1), pp. 1 - 16. https://doi.org/10.3390/nu11010076

Journal article

The impact of morning versus afternoon exercise on iron absorption in athletes
McCormick, Rachel H., Moretti, Diego, McKay, Alannah A., Laarakkers, Coby M., Vanswelm, Rachel, Trinder, Debbie, Cox, Gregory R., Zimmerman, Michael B., Sim, Marc, Goodman, Carmel, Dawson, Brian and Peeling, Peter. (2019). The impact of morning versus afternoon exercise on iron absorption in athletes. Medicine and Science in Sports and Exercise. 51(10), pp. 2147 - 2155. https://doi.org/10.1249/MSS.0000000000002026

Journal article

Is brain connectome research the future frontier for subjective cognitive decline? A systematic review
Lazarou, Ioulietta, Nikolopoulos, Spiros, Dimitriadis, Stavros I., Kompatsiaris, Ioannis Yiannis, Spilioti, Martha and Tsolaki, Magda. (2019). Is brain connectome research the future frontier for subjective cognitive decline? A systematic review. Clinical Neurophysiology. 130(10), pp. 1762 - 1780. https://doi.org/10.1016/j.clinph.2019.07.004

Journal article

Controversies in the science of sedentary behaviour and health: Insights, perspectives and future directions from the 2018 Queensland Sedentary Behaviour Think Tank
Biddle, Stuart J. H., Bennie, Jason A., Cocker, Katrien De, Dunstan, David, Gardiner, Paul A., Healy, Genevieve N., Lynch, Brigid, Owen, Neville, Brakenridge, Charlotte L., Brown, Wendy, Buman, Matthew, Clark, Bronwyn, Dohrn, Ing-Mari, Duncan, Mitch, Gilson, Nicholas, Kolbe-Alexander, Tracy, Pavey, Toby, Reid, Natasha, Vandelanotte, Corneel, ... Vincent, Grace E.. (2019). Controversies in the science of sedentary behaviour and health: Insights, perspectives and future directions from the 2018 Queensland Sedentary Behaviour Think Tank. International Journal of Environmental Research and Public Health. 16(23), pp. 1 - 20. https://doi.org/10.3390/ijerph16234762

Journal article

2018 AHA/ACC guideline for the management of adults with congenital heart disease [Executive summary]
Stout, Karen K., Daniels, Curt J., Aboulhosn, Jamil A., Bozkurt, Biykem, Broberg, Craig S., Colman, Jack M., Crumb, Stephen R., Dearani, Joseph A., Fuller, Stephanie, Gurvitz, Michelle Z., Khairy, Paul, Landzberg, Michael J., Saidi, Arwa, Valente, Anne Marie, Van Hare, George F. and Riegel, Barbara. (2019). 2018 AHA/ACC guideline for the management of adults with congenital heart disease [Executive summary]. Journal of the American College of Cardiology. 73(12), pp. 1494 - 1563. https://doi.org/10.1016/j.jacc.2018.08.1028

Journal article

Hydration in sport and exercise
Burke, Louise. (2019). Hydration in sport and exercise. In In J. D. Périard and S. Racinais (Ed.). Heat stress in sport and exercise pp. 113 - 137 Springer Nature Switzerland AG. https://doi.org/10.1007/978-3-319-93515-7_6

Book chapter

Early post-intensive care syndrome among older adult sepsis survivors receiving home care
Riegel, Barbara, Huang, Liming, Mikkelsen, Mark E., Kutney-Lee, Ann, Hanlon, Alexandra L., Murtaugh, Christopher M. and Bowles, Kathryn H.. (2019). Early post-intensive care syndrome among older adult sepsis survivors receiving home care. Journal of the American Geriatrics Society. 67(3), pp. 520 - 526. https://doi.org/10.1111/jgs.15691

Journal article

Objectively-assessed patterns and reported domains of sedentary behaviour among Japanese older adults
Shibata, Ai, Oka, Koichiro, Ishii, Kaori, Miyawaki, Rina, Inoue, Shigeru, Sugiyama, Takemi and Owen, Neville. (2019). Objectively-assessed patterns and reported domains of sedentary behaviour among Japanese older adults. Journal of Epidemiology. 29(9), pp. 334 - 339. https://doi.org/10.2188/jea.JE20180041

Journal article

Focal application of accelerated iTBS results in global changes in graph measures
Klooster, Deborah C. W., Franklin, Suzanne L., Besseling, René M. H., Jansen, Jaap F. A., Caeyenberghs, Karen, Duprat, Romain, Aldenkamp, Albert P., de Louw, Anton J. A., Boon, Paul A. J. M. and Baeken, Chris. (2019). Focal application of accelerated iTBS results in global changes in graph measures. Human Brain Mapping. 40(2), pp. 432 - 450. https://doi.org/10.1002/hbm.24384

Journal article

Heart failure care dyadic typology: Initial conceptualization, advances in thinking, and future directions of a clinically relevant classification system
Buck, Harleah G., Hupcey, Judith, Juárez-Vela, Raul, Vellone, Ercole and Riegel, Barbara. (2019). Heart failure care dyadic typology: Initial conceptualization, advances in thinking, and future directions of a clinically relevant classification system. Journal of Cardiovascular Nursing. 34(2), pp. 159 - 165. https://doi.org/10.1097/JCN.0000000000000548

Journal article

Differential impact of heart failure with reduced ejection fraction on men and women
Dewan, Pooja, Rorth, Rasmus, Jhund, Pardeep S., Shen, Li, Raparelli, Valeria, Petrie, Mark C., Abraham, William T., Desai, Akshay S., Dickstein, Kenneth, Kober, Lars, Mogensen, Ulrik M., Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R. and McMurray, John J. V.. (2019). Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology. 73(1), pp. 29 - 40. https://doi.org/10.1016/j.jacc.2018.09.081

Journal article

Statins in the prevention and treatment of heart failure: A review of the evidence
Lee, Matthew M. Y., Sattar, Naveed, McMurray, John J. V. and Packard, Chris J.. (2019). Statins in the prevention and treatment of heart failure: A review of the evidence. Current Atherosclerosis Reports. 21(10), pp. 1 - 8. https://doi.org/10.1007/s11883-019-0800-z

Journal article

The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes
McKay, Alannah K.A., Pyne, David B., Peeling, Peter, Sharma, Avish P., Ross, Megan L. R. and Burke, Louise M.. (2019). The impact of chronic carbohydrate manipulation on mucosal immunity in elite endurance athletes. Journal of Sports Sciences. 37(5), pp. 553 - 559. https://doi.org/10.1080/02640414.2018.1521712

Journal article

Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Cumming, Toby B., Holliday, Elizabeth G., Dunstan, David and English, Coralie. (2019). Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012). Journal of Stroke and Cerebrovascular Diseases. 28(4), pp. 963 - 970. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.020

Journal article

Discontinuation of angiotensin-converting enzyme inhibitors or beta-blockers and the impact on heart failure hospitalization rates
Knafl, George J., Moser, Debra K., Wu, Jia-Rong and Riegel, Barbara. (2019). Discontinuation of angiotensin-converting enzyme inhibitors or beta-blockers and the impact on heart failure hospitalization rates. European Journal of Cardiovascular Nursing. 18(8), pp. 667 - 678. https://doi.org/10.1177/1474515119860321

Journal article

Age-related characteristics and outcomes of patients with heart failure with preserved ejection fraction
Tromp, Jasper, Shen, Li, Jhund, Pardeep S., Anand, Inder S., Carson, Peter E., Desai, Akshay S., Granger, Christopher B., Komajda, Michel, McKelvie, Robert S., Pfeffer, Marc A., Solomon, Scott D., Køber, Lars, Swedberg, Karl, Zile, Michael R., Pitt, Bertram, Lam, Carolyn S. P. and McMurray, John J. V.. (2019). Age-related characteristics and outcomes of patients with heart failure with preserved ejection fraction. Journal of the American College of Cardiology. 74(5), pp. 601 - 612. https://doi.org/10.1016/j.jacc.2019.05.052

Journal article

A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men
Smiles, William J., Churchward-Venne, Tyler A., van Loon, Luc J. C., Hawley, John A. and Camera, Donny M.. (2019). A single bout of strenuous exercise overcomes lipid-induced anabolic resistance to protein ingestion in overweight, middle-aged men. The FASEB Journal. 33(6), pp. 7009 - 7017. https://doi.org/10.1096/fj.201801917R

Journal article