Efficacy of social cognition and interaction training in outpatients with schizophrenia spectrum disorders : Randomized controlled trial
Journal article
Fiszdon, Joanna M., Dixon, H. Drew, Davidson, Charlie A., Roberts, David L., Penn, David L. and Bell, Morris D.. (2023). Efficacy of social cognition and interaction training in outpatients with schizophrenia spectrum disorders : Randomized controlled trial. Frontiers in Psychiatry. 14, p. Article 1217735. https://doi.org/10.3389/fpsyt.2023.1217735
Authors | Fiszdon, Joanna M., Dixon, H. Drew, Davidson, Charlie A., Roberts, David L., Penn, David L. and Bell, Morris D. |
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Abstract | Given the relationship between social cognition and functional outcome in schizophrenia, a number of social cognitive interventions have been developed, including Social Cognition Interaction Training (SCIT), a group-based, comprehensive, manualized intervention. In the current trial, we examined SCIT efficacy as well as potential moderators of treatment effects. Fifty-one outpatients were randomized to SCIT or a wait-list-control (WLC), with assessments of social cognition, neurocognition, self-report, symptoms, and functioning conducted at baseline and end of the active phase. Relative to WLC, we did not find significant improvements for SCIT on neurocognition, social cognition, self-report, or symptoms, though there was a trend-level, medium effect favoring the SCIT condition on interpersonal and instrumental role function. Post-hoc analyses indicated that baseline neurocognition did not impact degree of social cognitive or functional change. Shorter duration of illness was significantly associated with better post-training neurocognition and self-esteem and, at trend-level with better symptoms and social functioning. We discuss the importance of outcome measure selection and the need for continued evaluation of potential treatment moderators in order to better match people to existing treatments. Clinical trial registration: Clinicaltrials.gov, Identifier NCT00587561. |
Keywords | social cognition; randomized controlled trial; schizophrenia; psychosis; training; rehabilitation |
Year | 2023 |
Journal | Frontiers in Psychiatry |
Journal citation | 14, p. Article 1217735 |
Publisher | Frontiers Media S.A. |
ISSN | 1664-0640 |
Digital Object Identifier (DOI) | https://doi.org/10.3389/fpsyt.2023.1217735 |
PubMed ID | 37599886 |
Scopus EID | 2-s2.0-85168373956 |
PubMed Central ID | PMC10436290 |
Open access | Published as ‘gold’ (paid) open access |
Page range | 1-10 |
Funder | Department of Veterans Affairs, United States of America |
Publisher's version | License File Access Level Open |
Output status | Published |
Publication dates | |
Online | 04 Aug 2023 |
Publication process dates | |
Accepted | 14 Jul 2023 |
Deposited | 04 Apr 2025 |
Grant ID | D4628W |
Additional information | © 2023 Fiszdon, Dixon, Davidson, Roberts, Penn and Bell. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
https://acuresearchbank.acu.edu.au/item/9193z/efficacy-of-social-cognition-and-interaction-training-in-outpatients-with-schizophrenia-spectrum-disorders-randomized-controlled-trial
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OA_Fiszdon_2023_Efficacy_of_social_cognition_and_interaction.pdf | |
License: CC BY 4.0 | |
File access level: Open |
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