Autistic symptoms predict social cognitive performance in patients with schizophrenia
Journal article
Deste, Giacomo, Vita, Antonio, Penn, David L., Pinkham, Amy E., Nibbio, Gabriele and Harvey, Philip D.. (2020). Autistic symptoms predict social cognitive performance in patients with schizophrenia. Schizophrenia Research. 215, pp. 113-119. https://doi.org/10.1016/j.schres.2019.11.008
Authors | Deste, Giacomo, Vita, Antonio, Penn, David L., Pinkham, Amy E., Nibbio, Gabriele and Harvey, Philip D. |
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Abstract | Schizophrenia spectrum disorders and Autism Spectrum Disorders (ASD) share many similarities. Among those features, social cognitive impairment is recognized as a key characteristic of both ASD and schizophrenia. In this study, the role of ASD symptoms, measured with the PANSS Autism Severity Score (PAUSS), was investigated as a predictor of social cognitive performance in patients with Schizophrenia spectrum disorders. Existent databases from 2 studies (SCOPE Phase 3 and SCOPE Phase 5), in which a total of 361 patients (mean age 41.7 years; 117 females) were assessed with tests of mental state attribution and emotion recognition, were analyzed. Less severe ASD symptoms, as well as younger age, better premorbid IQ, and neurocognition were identified as individual predictors of better social cognitive performance. These results suggest a role of ASD symptoms in affecting social cognitive performance in schizophrenia. |
Keywords | schizophrenia; schizoaffective; autism spectrum disorder; social cognition; PAUSS; neurocognition |
Year | 2020 |
Journal | Schizophrenia Research |
Journal citation | 215, pp. 113-119 |
Publisher | Elsevier B.V. |
ISSN | 0920-9964 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.schres.2019.11.008 |
PubMed ID | 31780344 |
Scopus EID | 2-s2.0-85075873289 |
PubMed Central ID | PMC7035981 |
Open access | Published as green open access |
Page range | 113-119 |
Funder | National Institute of Mental Health (NIMH), United States of America |
Author's accepted manuscript | License File Access Level Open |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 25 Nov 2019 |
Publication process dates | |
Accepted | 04 Nov 2019 |
Deposited | 19 May 2021 |
Grant ID | RO1MH093432 |
https://acuresearchbank.acu.edu.au/item/8w189/autistic-symptoms-predict-social-cognitive-performance-in-patients-with-schizophrenia
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Author's accepted manuscript
AM_Deste_2020_Autistic_symptoms_predict_social_cognitive_performance.pdf | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
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