Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin
Journal article
Harley, Geoff, Katerelos, Marina, Gleich, Kurt, de Souza, David P., Narayana, Vinod K., Kemp, Bruce E., Power, David A. and Mount, Peter F.. (2022). Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin. Biomedicine and Pharmacotherapy. 153, p. Article 113377. https://doi.org/10.1016/j.biopha.2022.113377
Authors | Harley, Geoff, Katerelos, Marina, Gleich, Kurt, de Souza, David P., Narayana, Vinod K., Kemp, Bruce E., Power, David A. and Mount, Peter F. |
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Abstract | Background Methods Findings Interpretation |
Keywords | fatty acid oxidation; Acetyl-CoA carboxylase; cisplatin-induced acute kidney injury; metformin; phosphorylation; metabolomics; AMP-activated protein kinase |
Year | 2022 |
Journal | Biomedicine and Pharmacotherapy |
Journal citation | 153, p. Article 113377 |
Publisher | Elsevier Masson SAS |
ISSN | 0753-3322 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.biopha.2022.113377 |
Scopus EID | 2-s2.0-85133884522 |
Open access | Published as ‘gold’ (paid) open access |
Page range | 1-14 |
Funder | National Health and Medical Research Council (NHMRC) |
University of Melbourne | |
Publisher's version | License File Access Level Open |
Output status | Published |
Publication dates | |
Online | 12 Jul 2022 |
Publication process dates | |
Accepted | 06 Jul 2022 |
Deposited | 06 Dec 2022 |
Supplemental file | License File Access Level Open |
Grant ID | 2010600 |
https://acuresearchbank.acu.edu.au/item/8y883/blocking-ampk-signalling-to-acetyl-coa-carboxylase-increases-cisplatin-induced-acute-kidney-injury-and-suppresses-the-benefit-of-metformin
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OA_Harley_2022_Blocking_AMPK_signalling_to_acetyl-CoA.pdf | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
Supplemental file
OA_Harley_2022_Blocking_AMPK_signalling_to_acetyl_CoA_[GRAPHICAL_ABSTRACT].jpg | |
License: CC BY-NC-ND 4.0 | |
File access level: Open |
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