AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model
Journal article
Smith, Tyler K. T., Ghorbani, Peyman, LeBlond, Nicholas D., Nunes, Julia R. C., O'Dwyer, Conor, Ambursley, Nia, Fong-McMaster, Claire, Minarrieta, Lucía, Burkovsky, Leah A., El-Hakim, Rama, Trzaskalski, Natasha A., Locatelli, Cassandra A. A., Stotts, Cameron, Pember, Ciara, Rayner, Katey J., Kemp, Bruce E., Loh, Kim, Harper, Mary-Ellen, Mulvihill, Erin E., ... Fullerton, Morgan D.. (2024). AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model. Atherosclerosis. 397, p. Article 117608. https://doi.org/10.1016/j.atherosclerosis.2024.117608
Authors | Smith, Tyler K. T., Ghorbani, Peyman, LeBlond, Nicholas D., Nunes, Julia R. C., O'Dwyer, Conor, Ambursley, Nia, Fong-McMaster, Claire, Minarrieta, Lucía, Burkovsky, Leah A., El-Hakim, Rama, Trzaskalski, Natasha A., Locatelli, Cassandra A. A., Stotts, Cameron, Pember, Ciara, Rayner, Katey J., Kemp, Bruce E., Loh, Kim, Harper, Mary-Ellen, Mulvihill, Erin E., St-Pierre, Julie and Fullerton, Morgan D. |
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Abstract | Background and aims Methods Results Conclusions |
Keywords | atherosclerosis; AMPK; HMGCR; cholesterol; inflammation; hematopoiesis; immunometabolism |
Year | 2024 |
Journal | Atherosclerosis |
Journal citation | 397, p. Article 117608 |
Publisher | Elsevier B.V. |
ISSN | 1879-1484 |
0021-9150 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.atherosclerosis.2024.117608 |
PubMed ID | 38880706 |
Scopus EID | 2-s2.0-85196028897 |
Funder | Canadian Institutes of Health Research (CIHR) |
University of Ottawa | |
Heart and Stroke Foundation of Canada | |
Canada Research Chairs Program | |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 18 Sep 2024 |
Publication process dates | |
Accepted | 30 May 2024 |
Deposited | 09 Feb 2025 |
Grant ID | PJT148634 |
MSH-141981 |
https://acuresearchbank.acu.edu.au/item/91527/ampk-mediated-regulation-of-endogenous-cholesterol-synthesis-does-not-affect-atherosclerosis-in-a-murine-pcsk9-aav-model
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