Moderated online social therapy for carers of young people recovering from firstepisode psychosis: study protocol for a randomised controlled trial

Journal article


Gleeson, John, Lederman, Reeva, Herrman, Helen, Koval, Peter, Eleftheriadis, Dina, Bendall, Sarah, Cotton, Sue and Alvarez-Jimenez, Mario 2017. Moderated online social therapy for carers of young people recovering from firstepisode psychosis: study protocol for a randomised controlled trial. Trials. 18, pp. 1 - 11. https://doi.org/10.1186/s13063-016-1775-5
AuthorsGleeson, John, Lederman, Reeva, Herrman, Helen, Koval, Peter, Eleftheriadis, Dina, Bendall, Sarah, Cotton, Sue and Alvarez-Jimenez, Mario
Abstract

Background: First-episode psychosis most often has its onset during late adolescence. In caring for the young person, families endure high levels of stress and depression. Meanwhile, the social networks of families often erode. Our group has previously shown that family cognitive behaviour therapy (CBT) leads to significantly improved perceived stress compared with specialist first-episode treatment as usual; however, there are well-known barriers to the dissemination of effective family interventions. To address this, we have developed a novel online intervention entitled ‘Altitudes’ that fully integrates purpose-built online social networking, expert and peer moderation, and evidence-based psychoeducation within a single application. The primary aim of this trial is to evaluate the effectiveness of Altitudes in reducing stress in carers over a 6-month period. Methods/design: We describe here a single-blinded cluster randomised controlled trial (cRCT) with permutated blocks. The clusters comprise individual families. The two treatment conditions include Altitudes plus Specialist Treatment as Usual (STAU) and STAU alone. Altitudes involves participation in our novel online programme whereas STAU comprises specialist family work at the Early Psychosis Prevention and Intervention Centre (EPPIC), Melbourne, Australia. We aim to recruit 160 family members of young, 15–27 year-old, patients registered for treatment for firstepisode psychosis (FEP) at EPPIC. The design includes two assessment time points, namely, baseline and 6-month follow-up. The study is due for completion within 2 years including an 18-month recruitment period and a 6- month treatment phase. The primary outcome is carers’ perceived stress at 6 months. Secondary outcome measures include a biomarker of stress, depressive symptoms, worry, substance use, loneliness, social support, satisfaction with life, and a range of measures that tap into coping resources. We seek to gain a dynamic picture of carer stress through our Smartphone Ecological Momentary Assessment (SEMA) tool. Discussion: This is the first randomised controlled trial designed to evaluate an online intervention for carers of young people recovering from FEP. It has the potential to produce evidence in support of a highly novel, accessible, and cost-effective intervention to reduce stress in carers who are providing support to young people at a critical phase in their recovery from psychosis. Trial registration: Australian New Zealand Clinical

Keywordsfirst-episode psychosis; carers; family intervention; eHealth; randomised controlled trial
Year2017
JournalTrials
Journal citation18, pp. 1 - 11
PublisherBiomed Central Ltd
ISSN1745-6215
Digital Object Identifier (DOI)https://doi.org/10.1186/s13063-016-1775-5
Scopus EID2-s2.0-85011382926
Open accessOpen access
Page range1 - 11
Research GroupSchool of Philosophy
Publisher's version
License
Place of publicationUnited Kingdom
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The Jumping-to-Conclusions Bias in New Religious Movements
Lim, Michelle, Gleeson, John and Jackson, Henry J. 2012. The Jumping-to-Conclusions Bias in New Religious Movements. The Journal of Nervous and Mental Disease. 200 (10), pp. 868 - 875. https://doi.org/10.1097/NMD.0b013e31826b6eb4
The relationship between impulsivity and vocational outcome in outpatient youth with borderline personality features
Sio, I. T., Chanen, A., Killackey, E. and Gleeson, John 2011. The relationship between impulsivity and vocational outcome in outpatient youth with borderline personality features. Early Intervention in Psychiatry (print version). 5 (3), pp. 249 - 253. https://doi.org/10.1111/j.1751-7893.2011.00271.x
Prediction of a single psychotic episode :A 7.5-year, prospective study in first-episode psychosis
Alvarez-Jimenez, Mario, Gleeson, John, Henry, Lisa, Harrigan, Susan, Harris, Meredith, Amminger, G, Killackey, Eoin, Yung, Alison, Herrman, Helen, Jackson, Henry and McGorry, Patrick 2011. Prediction of a single psychotic episode :A 7.5-year, prospective study in first-episode psychosis. Schizophrenia Research. 125 (2/3), pp. 236 - 246. https://doi.org/10.1016/j.schres.2010.10.020
Selective attention to treat bias in delusion-prone individuals
Lim, Michelle H., Gleeson, John and Jackson, Henry J. 2011. Selective attention to treat bias in delusion-prone individuals. Journal of Nervous and Mental Disease (print version). 199 (10), pp. 765 - 772. https://doi.org/10.1097/NMD.0b013e31822fc9e9
Reconsidering Culture and Self
Kashima, Yoshihisa, Koval, Peter and Kashima, Emiko S. 2011. Reconsidering Culture and Self. Psychological Studies. 56 (1), pp. 12 - 22.
Blaming, praising, and protecting our humanity: The implications of everyday dehumanization for judgments of moral status
Bastian, Brock, Laham, Simon M., Wilson, Sam, Haslam, Nick and Koval, Peter 2011. Blaming, praising, and protecting our humanity: The implications of everyday dehumanization for judgments of moral status. British Journal of Social Psychology. 50 (3), pp. 469 - 483. https://doi.org/10.1348/014466610X521383
Essentialist beliefs predict automatic motor-responses to social categories
Bastian, Brock, Loughnan, Stephen and Koval, Peter 2011. Essentialist beliefs predict automatic motor-responses to social categories. Group Processes and Intergroup Relations. 14 (4), pp. 559 - 567. https://doi.org/10.1177/1368430210385258
Supporting young people with psychosis in the community :An ICT enabled repalse prevention tool
Lederman, Reeva, Wadley, Greg, Gleeson, John, Alvarez-Jimenez, Mario and Spiteri-Staines, Anneliese 2011. Supporting young people with psychosis in the community :An ICT enabled repalse prevention tool. Pacific Asia Conference on Information Systems 2011. Australia: AIS Electronic Library. pp. 1 - 11
Supporting young people with psychosis in the community: An ICT enabled repalse prevention tool
Lederman, Reeva, Wadley, Greg, Gleeson, John, Alvarez-Jimenez, Mario and Spiteri-Staines, Anneliese 2011. Supporting young people with psychosis in the community: An ICT enabled repalse prevention tool. Pacific Asia Conference on Information Systems 2011. Australia: AIS Electronic Library. pp. 1 - 11
Preventing the second episode :A systematic review and Meta-analysis of Psychosocial and Pharmacological Trials in First-Episode psychosis
Alvarez-Jimenez, Mario, Parker, Alexandra, Hetrick, Sarah, McGorry, Patrick and Gleeson, John Francis Martin 2011. Preventing the second episode :A systematic review and Meta-analysis of Psychosocial and Pharmacological Trials in First-Episode psychosis. Schizophrenia Bulletin. 37 (3), pp. 619 - 630. https://doi.org/10.1093/schbul/sbp129
Selective Attention to Threat Bias in Delusion-Prone Individuals
Lim, Michelle H., Gleeson, John and Jackson, Henry J. 2011. Selective Attention to Threat Bias in Delusion-Prone Individuals. The Journal of Nervous and Mental Disease. 199 (10), pp. 765 - 772. https://doi.org/10.1097/NMD.0b013e31822fc9e9
Group programmes in early intervention services
Cotton, Sue, Luxmoore, Marni, Woodhead, Gina, Albiston, Dianne, Gleeson, John and McGorry, Patrick 2011. Group programmes in early intervention services. Early Intervention in Psychiatry. 5 (3), pp. 259 - 266. https://doi.org/10.1111/j.1751-7893.2011.00277.x
Differential predictors of critical comments and emotional over-involvement in first-episode psychosis
Alvarez-Jimenez, Mario, Gleeson, John Francis Martin, Cotton, Sue, Wade, Darryl, Crisp, Kingsley, Yap, M and McGorry, Patrick 2010. Differential predictors of critical comments and emotional over-involvement in first-episode psychosis. Psychological Medicine. 40 (1), pp. 63 - 72. https://doi.org/10.1017/S0033291708004765
Family Outcomes From a Randomized Control Trial of Relapse Prevention Therapy in First-Episode Psychosis
Gleeson, John Francis Martin, Cotton, Sue, Alvarez-Jimenez, Mario, Wade, Darryl, Crisp, Kingsley, Newman, Belinda, Spiliotacopoulos, Daniela and McGorry, Patrick 2010. Family Outcomes From a Randomized Control Trial of Relapse Prevention Therapy in First-Episode Psychosis. Journal of Clinical Psychiatry. 71 (4), pp. 475 - 783. https://doi.org/10.4088/JCP.08m04672yel
Quality of life in patients who have remitted from their first episode of psychosis
Cotton, Sue, Gleeson, John Francis Martin, Alvarez-Jimenez, Mario and McGorry, Patrick 2010. Quality of life in patients who have remitted from their first episode of psychosis. Schizophrenia Research. 121, pp. 259 - 265. https://doi.org/10.1016/j.schres.2010.05.027
Possible research area bias in the Excellence in Research for Australia (ERA) draft journal rankings
Haslam, Nick and Koval, Peter 2010. Possible research area bias in the Excellence in Research for Australia (ERA) draft journal rankings. Australian Journal of Psychology. 62 (2), pp. 112 - 114. https://doi.org/10.1080/00049530903334489
A systematic review of relapse measurement in randomized controlled trials of relapse prevention in first-episode psychosis
Gleeson, John Francis Martin, Alvarez-Jimenez, Mario, Cotton, Sue, Parker, Alexandra and Hetrick, Sarah 2010. A systematic review of relapse measurement in randomized controlled trials of relapse prevention in first-episode psychosis. Schizophrenia Research. 119 (1-3), pp. 79 - 88. https://doi.org/10.1016/j.schres.2010.02.1073
A systematic review of relapse measurement in randomized controlled trials of relapse prevention in first-episode psychosis
Gleeson, John Francis Martin, Alvarez-Jimenez, Mario, Cotton, Sue, Parker, Alexandra and Hetrick, Sarah 2010. A systematic review of relapse measurement in randomized controlled trials of relapse prevention in first-episode psychosis. Schizophrenia Research. 119 (1-3), pp. 79 - 88. https://doi.org/10.1016/j.schres.2010.02.1073
The reliability and validity of the alcohol, smoking and substance involvement screening test (assist)
Hides, L., Cotton, Sue, Berger, G., Gleeson, John, O'Donnell, C., Proffitt, T., McGorry, Patrick and Lubman, Dan 2009. The reliability and validity of the alcohol, smoking and substance involvement screening test (assist). Addictive Behaviors. 34 (10), pp. 821 - 825. https://doi.org/10.1016/j.addbeh.2009.03.040
Predictors of adherence to cognitive-behavioural therapy in first-episode psychosis
Álvarez-Jiménez, Mario, Gleeson, John, Cotton, Sue, Wade, Darryl, Gee, Donna, Pearce, Tracey, Crisp, Kingsley, Spiliotacopoulos, Daniela, Newman, Belinda and McGorry, Patrick 2009. Predictors of adherence to cognitive-behavioural therapy in first-episode psychosis. Journal of Clinical Psychiatry. 54 (10), pp. 710 - 718. https://doi.org/10.1177/070674370905401008
One Ace and three faults don't win the set
Álvarez-Jiménez, Mario, Hetrick, Sarah, Gonzalez-Blanch, Cesar, Gleeson, John and McGorry, Patrick 2009. One Ace and three faults don't win the set. British Journal of Psychiatry. 194 (1), pp. 89 - 89. https://doi.org/10.1192/bjp.194.1.89
A randomized controlled trial of relapse prevention therapy for first-episode psychosis patients
Gleeson, John, Cotton, Sue, Álvarez-Jiménez, Mario, Wade, Darryl, Gee, Donna, Crisp, Kingsley, Pearce, Tracey, Newman, Belinda, Spiliotacopoulos, Daniela, Castle, David J. and McGorry, Patrick 2009. A randomized controlled trial of relapse prevention therapy for first-episode psychosis patients. Journal of Clinical Psychiatry. 70 (4), pp. 477 - 486. https://doi.org/10.4088/JCP.08m04407
The episode ii trial of cognitive and family therapy for relapse prevention in early psychosis: Rationale and sample characteristics
Gleeson, John, Wade, Darryl, Castle, David J., Gee, Donna, Crisp, Kingsley, Pearce, Tracey, Newman, Belinda, Cotton, Sue, Álvarez-Jiménez, Mario, Gilbert, Monica and McGorry, Patrick 2008. The episode ii trial of cognitive and family therapy for relapse prevention in early psychosis: Rationale and sample characteristics. Journal of Mental Health. 17 (1), pp. 19 - 32. https://doi.org/10.1080/09638230701504999
Small shifts in diurnal rhythms are associated with an increase in suicide: The effect of daylight saving
Berk, Michael, Dodd, Seetal, Hallam, Karen, Berk, Lesley, Gleeson, John and Henry, Margaret 2008. Small shifts in diurnal rhythms are associated with an increase in suicide: The effect of daylight saving. Sleep and Biological Rhythm. 6 (1), pp. 22 - 25. https://doi.org/10.1111/j.1479-8425.2007.00331.x
Non-pharmacological management of antipsychotic-induced weight gain: systematic review and meta-analysis of randomised controlled trials
Álvarez-Jiménez, Mario, Hetrick, Sarah, Gonzalez-Blanch, Cesar, Gleeson, John and McGorry, Patrick 2008. Non-pharmacological management of antipsychotic-induced weight gain: systematic review and meta-analysis of randomised controlled trials. British Journal of Psychiatry. 193 (2), pp. 101 - 107. https://doi.org/10.1192/bjp.bp.107.042853
Evidence of semantic processing abnormalities in schizotypy using an indirect semantic priming task
Johnston, Alana, Rossell, Susan and Gleeson, John 2008. Evidence of semantic processing abnormalities in schizotypy using an indirect semantic priming task. Journal of Nervous and Mental Disease. 196 (9), pp. 694 - 701. https://doi.org/10.1097/NMD.0b013e318183f882
Acute-phase and 1-year follow-up results of a randomized controlled trial of cbt versus befriending for first-episode psychosis: The ace project
Jackson, Henry, McGorry, Patrick, Killackey, Eoin, Bendall, Sarah, Allott, Kelly, Dudgeon, P., Gleeson, John, Johnson, Tracy and Harrigan, Susan 2008. Acute-phase and 1-year follow-up results of a randomized controlled trial of cbt versus befriending for first-episode psychosis: The ace project. Psychological Medicine. 38 (5), pp. 725 - 735. https://doi.org/10.1017/S0033291707002061
The Credibility and Acceptability of Befriending as a Control Therapy in a Randomized Controlled Trial of Cognitive Behaviour Therapy for Acute First Episode Psychosis
Bendall, Sarah, Jackson, Henry, Killackey, Eoin, Allott, Kelly, Johnson, Tracy, Harrigan, Susan, Gleeson, John and McGorry, Patrick 2006. The Credibility and Acceptability of Befriending as a Control Therapy in a Randomized Controlled Trial of Cognitive Behaviour Therapy for Acute First Episode Psychosis. Behavioural and Cognitive Psychotherapy. 34 (3), pp. 277 - 291. https://doi.org/10.1017/S1352465806002815
The need for the development and evaluation of preventive psychosocial forensic interventions in mainstream adult community mental health services
Gleeson, John, Nathan, Pamela and Bradley, Gail 2006. The need for the development and evaluation of preventive psychosocial forensic interventions in mainstream adult community mental health services. Australasian Psychiatry. 14 (2), pp. 180 - 185. https://doi.org/10.1111/j.1440-1665.2006.02278.x
Exciting career opportunity beckons! Early intervention and vocational rehabilitation in first-episode psychosis: Employing cautious optimism
Killackey, Eoin, Jackson, Henry, Gleeson, John, Hickie, Ian and McGorry, Patrick 2006. Exciting career opportunity beckons! Early intervention and vocational rehabilitation in first-episode psychosis: Employing cautious optimism. Australian and New Zealand Journal of Psychiatry. 40 (44176), pp. 951 - 962. https://doi.org/10.1111/j.1440-1614.2006.01918.x
Agreeableness and neuroticism as predictors of relapse after first-episode psychosis
Gleeson, John, Rawlings, David, Jackson, Henry and McGorry, Patrick 2005. Agreeableness and neuroticism as predictors of relapse after first-episode psychosis. Journal of Nervous and Mental Disease. 193 (3), pp. 160 - 169. https://doi.org/10.1097/01.nmd.0000154841.99550.d3
Implementing cognitive-behavioural therapy for first-episode psychosis
Addington, Jean and Gleeson, John 2005. Implementing cognitive-behavioural therapy for first-episode psychosis. British Journal of Psychiatry. 13 (4), pp. 384 - 387. https://doi.org/10.1192/bjp.187.48.s72
Early warning signs of relapse following a first episode of psychosis.
Gleeson, John, Rawlings, David, Jackson, Henry and McGorry, Patrick 2005. Early warning signs of relapse following a first episode of psychosis. Schizophrenia Research. 80 (1), pp. 107 - 111. https://doi.org/10.1016/j.schres.2005.07.019