Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1
Journal article
Chisholm, Anita K., Lami, Francesca, Haebich, Kristina M., Ure, Alex, Brignell, Amanda, Maloof, Tiba, Pride, Natalie A., Walsh, Karin S., Maier, Alice, Rouel, Melissa, Granader, Yael, Barton, Belinda, Darke, Hayley, Fuelscher, Ian, Dabscheck, Gabriel, Anderson, Vicki A., Williams, Katrina, North, Kathryn N. and Payne, Jonathan M.. (2022). Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1. Journal of Autism and Developmental Disorders. 53, p. 2835–2850. https://doi.org/10.1007/s10803-022-05571-6
Authors | Chisholm, Anita K., Lami, Francesca, Haebich, Kristina M., Ure, Alex, Brignell, Amanda, Maloof, Tiba, Pride, Natalie A., Walsh, Karin S., Maier, Alice, Rouel, Melissa, Granader, Yael, Barton, Belinda, Darke, Hayley, Fuelscher, Ian, Dabscheck, Gabriel, Anderson, Vicki A., Williams, Katrina, North, Kathryn N. and Payne, Jonathan M. |
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Abstract | This study investigated sex and age differences in autistic behaviours in children with neurofibromatosis type 1 (NF1) who scored within the clinical range on the Social Responsiveness Scale - Second Edition (T score ≥ 60). Thirty-four males and 28 females (3–16 years) were assessed with the Autism Diagnostic Observation Schedule - Second Edition and Autism Diagnostic Interview - Revised. Across both measures, males exhibited greater social communication deficits relative to females. Age-related abatement of social communication difficulties was observed for males but not females. Conversely, no sex differences were found for restricted/repetitive behaviours, which were stable over time for both males and females. The findings are discussed within the context of broader neurodevelopmental considerations that are common in NF1. |
Keywords | neurofibromatosis type 1; autism; autistic; sex differences; age-related differences; children |
Year | 2022 |
Journal | Journal of Autism and Developmental Disorders |
Journal citation | 53, p. 2835–2850 |
Publisher | Springer |
ISSN | 0162-3257 |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s10803-022-05571-6 |
PubMed ID | 35445370 |
Scopus EID | 2-s2.0-85129624551 |
Web address (URL) | https://link.springer.com/article/10.1007/s10803-022-05571-6 |
Research or scholarly | Research |
Page range | 2835–2850 |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 20 Apr 2022 |
Publication process dates | |
Accepted | 10 Apr 2022 |
Deposited | 13 Mar 2023 |
https://acuresearchbank.acu.edu.au/item/8ywv4/sex-and-age-related-differences-in-autistic-behaviours-in-children-with-neurofibromatosis-type-1
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