Language growth in verbal autistic children from 5 to 11 years

Journal article


Brignell, Amanda, Williams, Katrina J., Reilly, Sheena and Morgan, Angela T.. (2024). Language growth in verbal autistic children from 5 to 11 years. Autism Research. 17(10), pp. 1994-2003. https://doi.org/10.1002/aur.3171
AuthorsBrignell, Amanda, Williams, Katrina J., Reilly, Sheena and Morgan, Angela T.
Abstract

To examine predictors and growth in language for verbal autistic and non-autistic children with/without low language from 4 to 11 years. Receptive and expressive language trajectories were compared in a community sample of 1026 children at ages 5, 7, and 11 years, across four groups: two autistic groups; one with and one without low language; and two non-autistic groups; one with and one without low language. Groups were delineated on baseline assessment at 4 years. Non-autistic and autistic children with low language had lower mean expressive language scores than the non-autistic typical language group (22.26 and 38.53 units lower, respectively, p < 0.001), yet demonstrated faster language growth across 5 to 11 years (p < 0.001 and p = 0.002, respectively). Both groups without low language had similar mean expressive language scores (p = 0.864) and a comparable rate of growth (p = 0.645). Language at 4 years was the only consistent predictor of language at 11 years for autistic children. Results were similar for receptive language in all analyses except there was no significant difference in rate of progress (slope) for the autistic with low language group compared with the typical language group (p = 0.272). Findings suggest early language ability, rather than a diagnosis of autism, is key to determining language growth and outcomes at 11 years in verbal children. Furthermore, children with low language showed developmental acceleration compared with same age peers.

Keywordsautism; developmental language disorder; language; language impairment; language trajectory
Year2024
JournalAutism Research
Journal citation17 (10), pp. 1994-2003
PublisherWiley Periodicals LLC
International Society for Autism Research
ISSN1939-3792
Digital Object Identifier (DOI)https://doi.org/10.1002/aur.3171
PubMed ID38828606
Scopus EID2-s2.0-85195180481
Open accessPublished as ‘gold’ (paid) open access
Page range1994-2003
FunderNational Health and Medical Research Council (NHMRC)
Operational Infrastructure Support (OIS) Program, Victorian Government
La Trobe University
Monash University
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online03 Jun 2024
Publication process dates
Accepted06 May 2024
Deposited26 May 2025
Grant ID237106
9436958
1041947
491210
1105008
1195955
1116976
Additional information

© 2024 The Author(s). Autism Research published by International Society for Autism Research and Wiley Periodicals LLC.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Permalink -

https://acuresearchbank.acu.edu.au/item/91x08/language-growth-in-verbal-autistic-children-from-5-to-11-years

Download files


Publisher's version
OA_Brignell_2024_Language_growth_in_verbal_autistic_children.pdf
License: CC BY-NC-ND 4.0
File access level: Open

  • 16
    total views
  • 3
    total downloads
  • 6
    views this month
  • 1
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Expanding the phenotype of Kleefstra syndrome : Speech, language and cognition in 103 individuals
Morison, Lottie D., Kennis, Milou G. P., Rots, Dmitrijs, Bouman, Arianne, Kummeling, Joost, Palmer, Elizabeth, Vogel, Adam P., Liégeois, Frédérique, Brignell, Amanda, Srivastava, Siddharth, Frazier, Zoe, Milnes, Di, Goel, Himanshu, Amor, David J., Scheffer, Ingrid E., Kleefstra, Tjitske and Morgan, Angela T.. (2024). Expanding the phenotype of Kleefstra syndrome : Speech, language and cognition in 103 individuals. Journal of Medical Genetics. 61(6), pp. 578-585. https://doi.org/10.1136/jmg-2023-109702
Patterns of psychotropic prescribing practices in autistic children and adolescents : An Australian perspective of two cohorts five years apart
Baldes, Anna, May, Tamara, Brignell, Amanda and Williams, Katrina. (2024). Patterns of psychotropic prescribing practices in autistic children and adolescents : An Australian perspective of two cohorts five years apart. Child Psychiatry and Human Development. pp. 1-15. https://doi.org/10.1007/s10578-024-01710-5
The nature of language impairments in children with cerebral palsy : A scoping review protocol
McInerney, Michelle, Pearce, Wendy and Brignell, Amanda. (2024). The nature of language impairments in children with cerebral palsy : A scoping review protocol. Advances in Communication and Swallowing. 27(2), pp. 101-105. https://doi.org/10.3233/ACS-240001
Simulation-based education for teaching aggression management skills to healthcare providers in acute healthcare settings : A systematic review
Mitchell, Marijke, Newall, Fiona, Bernie, Charmaine, Brignell, Amanda and Williams, Katrina. (2024). Simulation-based education for teaching aggression management skills to healthcare providers in acute healthcare settings : A systematic review. International Journal of Nursing Studies. 158, pp. 1-16. https://doi.org/10.1016/j.ijnurstu.2024.104842
Is language ability associated with behaviors of concern in autism? A systematic review
Chan, Charissa Ying Zhen, Williams, Katrina, May, Tamara, Wan, Wei Herng and Brignell, Amanda. (2023). Is language ability associated with behaviors of concern in autism? A systematic review. Autism Research. 16(2), pp. 250-270. https://doi.org/10.1002/aur.2855
Integrating interprofessional electronic medical record teaching in preregistration healthcare degrees : A case study
Lokmic-Tomkins, Zerina, Gray, Kathleen, Cheshire, Lisa, Parolini, Arno, Sharp, Megan, Tarrant, Bronwyn, Hill, Nicole, Rose, David, Webster, Marilyn, Virtue, Debra, Brignell, Amanda, Waring, Rebecca, Broussard, Fiona, Tsirgialos, Alex and Meng Cham, Kwang. (2023). Integrating interprofessional electronic medical record teaching in preregistration healthcare degrees : A case study. International Journal of Medical Informatics. 169, p. Article 104910. https://doi.org/10.1016/j.ijmedinf.2022.104910
Memantine for autism spectrum disorder
Brignell, Amanda, Marraffa, Catherine, Williams, Katrina and May, Tamara. (2022). Memantine for autism spectrum disorder. Cochrane Database of Systematic Reviews. 2022(8), p. Article CD013845. https://doi.org/10.1002/14651858.CD013845.pub2
Overall prognosis of preschool autism spectrum disorder diagnoses
Brignell, Amanda, Harwood, Rachael C., May, Tamara, Woolfenden, Susan, Montgomery, Alicia, Iorio, Alfonso and Williams, Katrina. (2022). Overall prognosis of preschool autism spectrum disorder diagnoses. Cochrane Database of Systematic Reviews. 2022(9), p. Article CD012749. https://doi.org/10.1002/14651858.CD012749.pub2
Delineating the autistic phenotype in children with neurofibromatosis type 1
Chisholm, Anita K., Haebich, Kristina M., Pride, Natalie A., Walsh, Karin S., Lami, Francesca, Ure, Alex, Maloof, Tiba, Brignell, Amanda, Rouel, Melissa, Granader, Yael, Maier, Alice, Barton, Belinda, Darke, Hayley, Dabscheck, Gabriel, Anderson, Vicki A., Williams, Katrina, North, Kathryn N. and Payne, Jonathon M.. (2022). Delineating the autistic phenotype in children with neurofibromatosis type 1. Molecular Autism. 13, p. Article 3. https://doi.org/10.1186/s13229-021-00481-3
Social motivation a relative strength in DYRK1A syndrome on a background of significant speech and language impairments
Morison, Lottie D., Braden, Ruth O., Amor, David J., Brignell, Amanda, van Bon, Bregje W. M. and Morgan, Angela T.. (2022). Social motivation a relative strength in DYRK1A syndrome on a background of significant speech and language impairments. European Journal of Human Genetics. 30(7), pp. 800-811. https://doi.org/10.1038/s41431-022-01079-w
Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1
Chisholm, Anita K., Lami, Francesca, Haebich, Kristina M., Ure, Alex, Brignell, Amanda, Maloof, Tiba, Pride, Natalie A., Walsh, Karin S., Maier, Alice, Rouel, Melissa, Granader, Yael, Barton, Belinda, Darke, Hayley, Fuelscher, Ian, Dabscheck, Gabriel, Anderson, Vicki A., Williams, Katrina, North, Kathryn N. and Payne, Jonathan M.. (2022). Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1. Journal of Autism and Developmental Disorders. 53, p. 2835–2850. https://doi.org/10.1007/s10803-022-05571-6
Memantine for autism spectrum disorder
Brignell, Amanda, Prakash, Chidambaram, Marraffa, Catherine, Williams, Katrina and May, Tamara. (2021). Memantine for autism spectrum disorder. Cochrane Database of Systematic Reviews. 2021(1), p. Article CD013845. https://doi.org/10.1002/14651858.CD013845
Identifying and supporting autistic preschoolers and their families
Brignell, Amanda, Cox, Georgina, Ure, Alexandra, Bernie, Charmaine and Williams, Katrina. (2021). Identifying and supporting autistic preschoolers and their families. Australian Journal of General Practice. 50(3), pp. 115-119. https://doi.org/10.31128/AJGP-11-20-5744
Interventions for children and adolescence who stutter : A systematic review, meta-analysis, and evidence map
Brignell, Amanda, Krahe, Michelle, Downes, Martin, Kefalianos, Elaina, Reilly, Sheena and Morgan, Angela. (2021). Interventions for children and adolescence who stutter : A systematic review, meta-analysis, and evidence map. Journal of Fluency Disorders. 70, p. Article 105843. https://doi.org/10.1016/j.jfludis.2021.105843
A modeling-guided case study of disordered speech in minimally verbal children with autism spectrum disorder
Chenausky Karen, V., Brignell, Amanda, Morgan Angela, T., Norton Andrea, C., Tager-Flusberg Helen, B., Schlaug, Gottfried and Guenther Frank, H.. (2021). A modeling-guided case study of disordered speech in minimally verbal children with autism spectrum disorder. American Journal of Speech-Language Pathology. 30(3S), pp. 1542-1557. https://doi.org/10.1044/2021_AJSLP-20-00121
A systematic review of interventions for adults who stutter
Brignell, Amanda, Krahe, Michelle, Downes, Martin, Kefalianos, Elaina, Reilly, Sheena and Morgan, Angela T.. (2020). A systematic review of interventions for adults who stutter. Journal of Fluency Disorders. 64, p. 105766. https://doi.org/10.1016/j.jfludis.2020.105766
Speech and language phenotype in Phelan-McDermid (22q13.3) syndrome
Brignell, Amanda, Gu, Conway, Holm, Alison, Carrigg, Bronwyn, Sheppard, Daisy A., Amor, David J. and Morgan, Angela T.. (2020). Speech and language phenotype in Phelan-McDermid (22q13.3) syndrome. European Journal of Human Genetics. 29(4), pp. 564-574. https://doi.org/10.1038/s41431-020-00761-1
Predicting speech-sound disorder outcomes in school-age children with hearing loss : The VicCHILD experience
St John, Miya, Columbus, Georgie, Brignell, Amanda, Carew, Peter, Skeat, Jemma, Reilly, Sheena and Morgan, Angela T.. (2020). Predicting speech-sound disorder outcomes in school-age children with hearing loss : The VicCHILD experience. International Journal of Language and Communication Disorders. 55(4), pp. 537-546. https://doi.org/10.1111/1460-6984.12536
No differences in code-related emergent literacy skills in well-matched 4-year-old children with and without ASD
Westerveld, Marleen F., Paynter, Jessica, Brignell, Amanda and Reilly, Sheena. (2020). No differences in code-related emergent literacy skills in well-matched 4-year-old children with and without ASD. Journal of Autism and Developmental Disorders. 50(8), pp. 3060-3065. https://doi.org/10.1007/s10803-020-04407-5
Factor analysis of signs of childhood apraxia of speech
Chenausky, Karen V., Brignell, Amanda, Morgan, Angela, Gagné, Danielle, Norton, Andrea, Tager-Flusberg, Helen, Schlaug, Gottfried, Shield, Aaron and Green, Jordan R.. (2020). Factor analysis of signs of childhood apraxia of speech. Journal of Communication Disorders. 87, p. 106033. https://doi.org/10.1016/j.jcomdis.2020.106033
Autism spectrum disorder prevalence in children aged 12–13 years from the longitudinal study of Australian children
May, Tamara, Brignell, Amanda and Williams, Katrina. (2020). Autism spectrum disorder prevalence in children aged 12–13 years from the longitudinal study of Australian children. Autism Research. 13(5), pp. 821-827. https://doi.org/10.1002/aur.2286
Preliminary evidence supports a range of speech sound interventions, but higher-quality studies are needed
Sanchez, Katherine, Brignell, Amanda and Morgan, Angela. (2019). Preliminary evidence supports a range of speech sound interventions, but higher-quality studies are needed. Evidence-based Communication Assessment and Intervention. 13(4), pp. 181-186. https://doi.org/10.1080/17489539.2019.1645982
Predictors and growth in receptive vocabulary from 4 to 8 years in children with and without autism spectrum disorder : A population-based study
Brignell, Amanda, May, Tamara, Morgan, Angela T. and Williams, Katrina. (2019). Predictors and growth in receptive vocabulary from 4 to 8 years in children with and without autism spectrum disorder : A population-based study. Autism: the international journal of research and practice. 23(5), pp. 1322-1334. https://doi.org/10.1177/1362361318801617
Inhibition of Upf2-dependent nonsense-mediated decay leads to behavioral and neurophysiological abnormalities by activating the immune response
Johnson, Jennifer L., Stoica, Loredana, Liu, Yuwei, Zhu, Ping Jun, Bhattacharya, Abhisek, Buffington, Shelly A., Huq, Redwan, Eissa, N. Tony, Larsson, Ola, Porse, Bo T., Domingo, Deepti, Nawaz, Urwah, Carroll, Renee, Jolly, Lachlan, Scerri, Tom S., Kim, Hyung-Goo, Brignell, Amanda, Coleman, Matthew J., Braden, Ruth, ... Costa-Mattioli, Mauro. (2019). Inhibition of Upf2-dependent nonsense-mediated decay leads to behavioral and neurophysiological abnormalities by activating the immune response. Neuron. 104(4), pp. 665-679. https://doi.org/10.1016/j.neuron.2019.08.027
A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder
Brignell, Amanda, Morgan, Angela T., Woolfenden, Susan, Klopper, Felicity, May, Tamara, Sarkozy, Vanessa and Williams, Katrina. (2018). A systematic review and meta-analysis of the prognosis of language outcomes for individuals with autism spectrum disorder. Autism & Developmental Language Impairments. 3, pp. 1-9. https://doi.org/10.1177/2396941518767610
Trends in the overlap of autism spectrum disorder and attention deficit hyperactivity disorder : Prevalence, clinical management, language and genetics
May, T., Brignell, A., Hawi, Z., Brereton, A., Tonge, B., Bellgrove, M. A. and Rinehart, N. J.. (2018). Trends in the overlap of autism spectrum disorder and attention deficit hyperactivity disorder : Prevalence, clinical management, language and genetics. Current Developmental Disorders Reports (online). 5(1), pp. 49-57. https://doi.org/10.1007/s40474-018-0131-8
Communication interventions for autism spectrum disorder in minimally verbal children
Brignell, A., Chenausky, K. V., Song, H., Zhu, J., Suo, C. and Morgan, A. T.. (2018). Communication interventions for autism spectrum disorder in minimally verbal children. Cochrane Database of Systematic Reviews. 2018(11), p. CD012324. https://doi.org/10.1002/14651858.CD012324.pub2
Patterns and predictors of language development from 4 to 7 years in verbal children with and without autism spectrum disorder
Brignell, Amanda, Williams, Katrina, Jachno, Kim, Prior, Margot, Reilly, Sheena and Morgan, Angela T.. (2018). Patterns and predictors of language development from 4 to 7 years in verbal children with and without autism spectrum disorder. Journal of Autism and Developmental Disorders. 48(10), pp. 3282-3295. https://doi.org/10.1007/s10803-018-3565-2
Characterization of speech and language phenotype in children with NRXN1 deletions
Brignell, Amanda, St John, Miya, Boys, Amber, Bruce, Amanda, Dinale, Carla, Pigdon, Lauren, Hildebrand, Michael S., Amor, David J. and Morgan, Angela T.. (2018). Characterization of speech and language phenotype in children with NRXN1 deletions. American Journal of Medical Genetics Part B : Neuropsychiatric Genetics. 177(8), pp. 700-708.
Childhood apraxia of speech in autism spectrum disorder
Brignell, Amanda, Dodd, Barbara, Sykes, Carolyn and Morgan, Angela. (2017). Childhood apraxia of speech in autism spectrum disorder. In In Dodd, Barbara and Morgan, Angela (Ed.). Intervention Case Studies of Child Speech Impairment pp. 137 J&R Press.
Parent-reported patterns of loss and gain in communication in 1- to 2-year-old children are not unique to autism spectrum disorder
Amanda Brignell, Katrina Williams, Margot Prior, Susan Donath, Sheena Reilly, Edith Bavin, Patricia Eadie and Angela Morgan. (2017). Parent-reported patterns of loss and gain in communication in 1- to 2-year-old children are not unique to autism spectrum disorder. Autism: the international journal of research and practice. 21(3), pp. 344-356. https://doi.org/10.1177/1362361316644729
Overall prognosis of preschool autism spectrum disorder diagnoses (Protocol)
Amanda Brignell, Natalia Albein-Urios, Susan Woolfenden, Andrew Hayen, Alfonso Iorio and Katrina Williams. (2017). Overall prognosis of preschool autism spectrum disorder diagnoses (Protocol). Cochrane Database of Systematic Reviews. 2017(8), pp. 1-18. https://doi.org/10.1002/14651858.CD012749
Autism spectrum disorder: Updated prevalence and comparison of two birth cohorts in a nationally representative Australian sample
Tamara May, Emma Sciberras, Amanda Brignell and Katrina Williams. (2017). Autism spectrum disorder: Updated prevalence and comparison of two birth cohorts in a nationally representative Australian sample. BMJ Open. 7(5), pp. 1-9. https://doi.org/10.1136/bmjopen-2016-015549
Communication intervention for autism spectrum disorders in minimally verbal children
Brignell, A., Song, H., Zhu, J., Suo, C., Lu, D. and Morgan, A. T.. (2016). Communication intervention for autism spectrum disorders in minimally verbal children. Cochrane Database of Systematic Reviews. 2016(11), p. Article CD012324. https://doi.org/10.1002/14651858.CD012324
Diagnosing autism : Australian paediatric research network surveys
Randall, Melinda, Albein-Urios, Natalia, Brignell, Amanda, Gulenc, Alisha, Hennel, Sabine, Coates, Cathy, Symeonides, Christos, Hiscock, Harriet, Marraffa, Catherine, Silove, Natalie, Bayl, Vivian, Woolfenden, Susan and Williams, Katrina. (2016). Diagnosing autism : Australian paediatric research network surveys. Journal of Paediatrics and Child Health. 52(1), pp. 11-17. https://doi.org/10.1111/jpc.13029
Regression in autism spectrum disorders
Williams, Katrina, Brignell, Amanda, Prior, Margot, Bartak, Lawrence and Roberts, Jacqueline. (2015). Regression in autism spectrum disorders. Journal of Paediatrics and Child Health. 51(1), pp. 61-64. https://doi.org/10.1111/jpc.12805
How relevant is the framework being used with autism spectrum disorders today?
Amanda Brignell, Angela Morgan, Susan Woolfenden and Katrina Williams. (2014). How relevant is the framework being used with autism spectrum disorders today? International Journal of Speech-Language Pathology. 16(1), pp. 43-49. https://doi.org/10.3109/17549507.2013.861870
Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD)
Williams, Katrina, Brignell, Amanda, Randall, Melinda Joy, Silove, Natalie and Hazell, Philip. (2013). Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD). Cochrane Database of Systematic Reviews. 8, pp. 1 - 51. https://doi.org/10.1002/14651858.CD004677.pub3