Effects of lifestyle intervention on left ventricular regional myocardial function in metabolic syndrome patients from the RESOLVE randomized trial

Journal article

Serrano-Ferrer, Juan, Crendal, Edward, Walther, Guillaume, Vinet, Agnes, Dutheil, Frederic, Naughton, Geraldine Ann, Lesourd, Bruno, Chapier, Robert, Courteix, Daniel and Obert, Philippe. (2016). Effects of lifestyle intervention on left ventricular regional myocardial function in metabolic syndrome patients from the RESOLVE randomized trial. Metabolism. 65(9), pp. 1350 - 1360. https://doi.org/10.1016/j.metabol.2016.05.006
AuthorsSerrano-Ferrer, Juan, Crendal, Edward, Walther, Guillaume, Vinet, Agnes, Dutheil, Frederic, Naughton, Geraldine Ann, Lesourd, Bruno, Chapier, Robert, Courteix, Daniel and Obert, Philippe
Abstract

Aims: The purpose of our study was to determine the effect of lifestyle intervention on left ventricular (LV) regional myocardial function in patients with metabolic syndrome (MetS) and investigate the relationships of the changes in myocardial function to changes in epicardial adipose tissue (EAT), inflammatory profile and MetS components. Methods: Eighty-seven MetS patients were enrolled in a 6 month lifestyle intervention program based on dietary management and increased physical activity, and compared with 44 aged and sex-matched healthy controls. MetS individuals were allocated to different groups randomized (computer-generated randomization) on exercise modalities (high-intensity dominant resistance or aerobic training, and moderate-intensity of both modes). EAT was measured by transthoracic echocardiography and LV longitudinal strains and strain rates were obtained using vector velocity imaging. Blood chemistry allowed assessments of adipocytokines (TNF-α: tumor necrosis factor α, PAI active: active plasminogen activator inhibitor-1 and adiponectin) and glucose tolerance markers. Results: Regardless of exercise training modalities, lifestyle intervention improved significantly LV strains and strain rates (p < 0.001) as well as metabolic and inflammatory profiles. Stepwise multiple regression analyses revealed EAT (β = 0.73, p < 0.01), log adiponectin (β = − 0.13, p < 0.05) and log TNF-α (β = 0.15, p < 0.05) as independent predictors of LV longitudinal strain (R2 = 0.74, p < 0.001) while myocardial function improvement consecutive to lifestyle intervention was explained by EAT changes only (R2 = 0.54, p < 0.001). Conclusion: The mechanisms through which regional myocardial function is impaired in MetS and improved consecutive to intervention involved EAT, possibly via paracrine effects of adipocytokines. EAT should be considered as a future therapeutic target of interest in the treatment of metabolic-related cardiac diseases.

Keywordsmetabolic syndrome; epicardial fat; inflammation; myocardial dysfunction; lifestyle intervention
Year2016
JournalMetabolism
Journal citation65 (9), pp. 1350 - 1360
PublisherChurchill Livingstone
ISSN0026-0495
Digital Object Identifier (DOI)https://doi.org/10.1016/j.metabol.2016.05.006
Page range1350 - 1360
Research GroupSports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre
Publisher's version
File Access Level
Controlled
Place of publicationUnited Kingdom
Permalink -

https://acuresearchbank.acu.edu.au/item/8q84z/effects-of-lifestyle-intervention-on-left-ventricular-regional-myocardial-function-in-metabolic-syndrome-patients-from-the-resolve-randomized-trial

Log in to edit

Restricted files

Publisher's version

  • 107
    total views
  • 0
    total downloads
  • 2
    views this month
  • 0
    downloads this month
These values are for the period from 19th October 2020, when this repository was created.

Export as

Related outputs

Efficacy of medical treatments for vernal keratoconjunctivitis : A systematic review and meta-analysis
Roumeau, Inès, Coutu, Adrien, Navel, Valentin, Pereira, Bruno, Baker, Julien S., Chiambaretta, Frédéric, Bremond-Gignac, Dominique and Dutheil, Frédéric. (2021). Efficacy of medical treatments for vernal keratoconjunctivitis : A systematic review and meta-analysis. Journal of Allergy and Clinical Immunology. 148(3), pp. 822-834. https://doi.org/10.1016/j.jaci.2021.03.026
Muscle function and architecture in children with juvenile idiopathic arthritis
Bourdier, Pierre, Birat, Anthony, Rochette, Emmanuelle, Doré, Éric, Courteix, Daniel, Dutheil, Frédéric, Pereira, Bruno, Ratel, Sébastien, Merlin, Etienne and Duché, Pascale. (2021). Muscle function and architecture in children with juvenile idiopathic arthritis. Acta Paediatrica. 110(1), pp. 280-287. https://doi.org/10.1111/apa.15335
Electromyographic assessment of the lower leg muscles during concentric and eccentric phases of standing heel raise
Ugbolue, Ukadike C., Yates, Emma L., Ferguson, Kerensa, Wearing, Scott C., Gu, Yaodong, Lam, Wing-Kai, Baker, Julien S., Dutheil, Frédéric, Sculthorpe, Nicholas F. and Dias, Tilak. (2021). Electromyographic assessment of the lower leg muscles during concentric and eccentric phases of standing heel raise. Healthcare. 9(465), pp. 1-15. https://doi.org/10.3390/healthcare9040465
Sedentary lifestyle matters as past sedentariness, not current sedentariness, predicts cognitive inhibition performance among college students : An exploratory study
Magnon, Valentin, Vallet, Guillaume T., Dutheil, Frédéric and Auxiette, Catherine. (2021). Sedentary lifestyle matters as past sedentariness, not current sedentariness, predicts cognitive inhibition performance among college students : An exploratory study. International Journal of Environmental Research and Public Health. 18(14), p. Article 7649. https://doi.org/10.3390/ijerph18147649
Facial width-to-height ratio underlies perceived dominance on facial emotional expressions
Merlhiot, Gaëtan, Mondillon, Laurie, Méot, Alain, Dutheil, Frederic and Mermillod, Martial. (2021). Facial width-to-height ratio underlies perceived dominance on facial emotional expressions. Personality and Individual Differences. 172, p. Article 110583. https://doi.org/10.1016/j.paid.2020.110583
A novel simplified biomechanical assessment of the heel pad during foot plantarflexion
Ugbolue, Ukadike C., Yates, Emma L., Rowland, Keir E., Wearing, Scott C., Gu, Yaodong, Lam, Wing-Kai, Baker, Julien S., Sculthorpe, Nicholas F. and Dutheil, Frédéric. (2021). A novel simplified biomechanical assessment of the heel pad during foot plantarflexion. Proceedings of the Institution of Mechanical, Engineers Part H: Journal of Engineering in Medicine. 235(2), pp. 197-207. https://doi.org/10.1177/0954411920971069
Severe undernutrition increases bleeding risk on vitamin-K antagonists
Moustafa, Farès, Dopeux, Loïc, Mulliez, Aurelien, Boirie, Yves, Morand, Christine, Gentes, Elodie, Farigon, Nicolas, Richard, Damien, Lebreton, Aurélien, Teissandier, Dorian, Dutheil, Frederic and Schmidt, Jeannot. (2021). Severe undernutrition increases bleeding risk on vitamin-K antagonists. Clinical Nutrition. 40(4), pp. 2237-2243. https://doi.org/10.1016/j.clnu.2020.10.002
Heart rate variability as a possible predictor of sport performance in junior rhythmic gymnastics
Urzeala, Constanta, Bota, Aura, Serbanoiu, Sorin, Mezei, Mariana, Dutheil, Frederic and Courteix, Daniel. (2020). Heart rate variability as a possible predictor of sport performance in junior rhythmic gymnastics. Isokinetics and Exercise Science. 28(2), pp. 171-179. https://doi.org/10.3233/IES-192222
Sex differences in heel pad stiffness during in vivo loading and unloading
Ugbolue, Ukadike C., Yates, Emma L., Wearing, Scott C., Gu, Yaodong, Lam, Wing-Kai, Valentin, Stephanie, Baker, Julien S., Dutheil, Frédéric and Sculthorpe, Nicholas F.. (2020). Sex differences in heel pad stiffness during in vivo loading and unloading. Journal of Anatomy. 237(3), pp. 520-528. https://doi.org/10.1111/joa.13207
Napping and cognitive performance during night shifts : A systematic review and meta-analysis
Dutheil, Frédéric, Bessonnat, Brice, Pereira, Bruno, Baker, Julien S., Moustafa, Fares, Fantini, Maria Livia, Mermillod, Martial and Navel, Valentin. (2020). Napping and cognitive performance during night shifts : A systematic review and meta-analysis. Sleep. 43(12), pp. 1-15. https://doi.org/10.1093/sleep/zsaa109
Prostate cancer and asbestos : A systematic review and meta-analysis
Dutheil, Frédéric, Zaragoza-Civale, Laetitia, Pereira, Bruno, Mermillod, Martial, Baker, Julien S., Schmidt, Jeannot, Moustafa, Fares and Navel, Valentin. (2020). Prostate cancer and asbestos : A systematic review and meta-analysis. The Permanente Journal. 24, pp. 1-10. https://doi.org/10.7812/TPP/19.086
Neurological soft signs and post-traumatic stress disorder : A biomarker of severity?
Belrose, Célia, Duffaud, Anais, Rakotoarison, Elsa, Faget, Catherine, Raynaud, Philippe, Dutheil, Frédéric, Boyer, Léa, Billaud, Jean-Baptiste and Trousselard, Marion. (2020). Neurological soft signs and post-traumatic stress disorder : A biomarker of severity? Frontiers in Psychiatry. 11, p. 533662. https://doi.org/10.3389/fpsyt.2020.533662
Suicide among physicians and health-care workers : A systematic review and meta-analysis
Dutheil, Frédéric, Aubert, Claire, Pereira, Bruno, Dambrun, Michael, Moustafa, Fares, Mermillod, Martial, Baker, Julien S., Trousselard, Marion, Lesage, François-Xavier and Navel, Valentin. (2019). Suicide among physicians and health-care workers : A systematic review and meta-analysis. PLoS ONE. 14(12), p. e0226361. https://doi.org/10.1371/journal.pone.0226361
Importance of considering interoceptive abilities in alexithymia assessment
Fournier, Alicia, Luminet, Olivier, Dambrun, Michael, Dutheil, Frédéric, Pellissier, Sonia and Mondillon, Laurie. (2019). Importance of considering interoceptive abilities in alexithymia assessment. PeerJ. 7, p. e7615. https://doi.org/10.7717/peerj.7615
Cognitive restriction accentuates the increased energy intake response to a 10-month multidisciplinary weight loss program in adolescents with obesity
Miguet, M., Masurier, J., Chaput, J. P., Pereira, B., Lambert, C., Dâmaso, A. R., Courteix, D., Duclos, M., Boirie, Y. and Thivel, D.. (2019). Cognitive restriction accentuates the increased energy intake response to a 10-month multidisciplinary weight loss program in adolescents with obesity. Appetite. 134, pp. 125-134. https://doi.org/10.1016/j.appet.2018.12.015
Efficacy of different procedures of intra-corneal ring segment implantation in keratoconus : A systematic review and meta-analysis
d'Azy, Cédric Benoist, Pereira, Bruno, Chiambaretta, Frédéric and Dutheil, Frédéric. (2019). Efficacy of different procedures of intra-corneal ring segment implantation in keratoconus : A systematic review and meta-analysis. Translational Vision Science and Technology. 8(3), p. 38. https://doi.org/10.1167/tvst.8.3.38
Effects of a short residential thermal spa program to prevent work-related stress/burnout on stress biomarkers: The thermstress proof of concept study
Dutheil, Frederic, Chaplais, Elodie, Vilmant, Audrey, Lanoir, Denise, Courteix, Daniel, Duche, Pascale, Abergel, Armand, Pfabigan, Daniela M., Han, Shihui, Mondillon, Laurie, Vallet, Guillaume, Mermillod, Martial, Boudet, Gil, Obert, Phillippe, Izem, Omar, Boirie, Yves, Pereira, Bruno and Lesage, Francois-Xavier. (2019). Effects of a short residential thermal spa program to prevent work-related stress/burnout on stress biomarkers: The thermstress proof of concept study. Journal of International Medical Research. 47(10), pp. 5130 - 5145. https://doi.org/10.1177/0300060519859119
Efficacy of treatments for demodex blepharitis: A systematic review and meta-analysis
Navel, Valentin, Mulliez, Aurélien, D'Azy, Cédric Benoist, Baker, Julien S., Malecaze, Jean, Chiambaretta, Frédéric and Dutheil, Frederic. (2019). Efficacy of treatments for demodex blepharitis: A systematic review and meta-analysis. The Ocular Surface. 17(4), pp. 655 - 669. https://doi.org/10.1016/j.jtos.2019.06.004
Stimulated thyroglobulin and thyroglobulin reduction index predict excellent response in differentiated thyroid cancers
Barres, Bertrand, Kelly, Antony, Kwiatkowski, Fabrice, Batisse-Lignier, Marie, Fouilhoux, Geneviève, Aubert, Bernadette, Dutheil, Frederic, Tauveron, Igor, Cachin, Florent and Maqdasy, Salwan. (2019). Stimulated thyroglobulin and thyroglobulin reduction index predict excellent response in differentiated thyroid cancers. The Journal of Clinical Endocrinology and Metabolism. 104(8), pp. 3462 - 3472. https://doi.org/10.1210/jc.2018-02680
Long-term effects of high-intensity resistance and endurance exercise on plasma leptin and ghrelin in overweight individuals: The RESOLVE Study
Tremblay, Angelo, Dutheil, Frédéric, Drapeau, Vicky, Metz, Lore, Lesour, Bruno, Chapier, Robert, Pereira, Bruno, Verney, Julien, Baker, Julien S., Vinet, Agnes, Walther, Guillaume, Obert, Phillippe, Courteix, Daniel and Thivel, David. (2019). Long-term effects of high-intensity resistance and endurance exercise on plasma leptin and ghrelin in overweight individuals: The RESOLVE Study. Applied Physiology, Nutrition and Metabolism. 44(11), pp. 1172 - 1179. https://doi.org/10.1139/apnm-2019-0019
The importance of recurrent top-down synaptic connections for the anticipation of dynamic emotions
Mermillod, Martial, Bourrier, Yannick, David, Erwan, Kauffmann, Louise, Chauvin, Alan, Guyader, Nathalie, Dutheil, Frederic and Peyrin, Carole. (2019). The importance of recurrent top-down synaptic connections for the anticipation of dynamic emotions. Neural Networks. 109, pp. 19 - 30. https://doi.org/10.1016/j.neunet.2018.09.007
Heart rate variability in type 2 diabetes mellitus : A systematic review and meta-analysis
Benichou, Thomas, Pereira, Bruno, Mermillod, Martial, Tauveron, Igor, Pfabigan, Daniela, Maqdasy, Salwan and Dutheil, Frédéric. (2018). Heart rate variability in type 2 diabetes mellitus : A systematic review and meta-analysis. PLoS ONE. 13(4), p. e0195166. https://doi.org/10.1371/journal.pone.0195166
Different modalities of exercise improve macrovascular function but not microvascular function in metabolic syndrome: The RESOLVE randomized trial
Agnes Vinet, Phillippe Obert, Daniel Courteix, Robert Chapier, Bruno Lesourd, Julien Verney, Frederic Dutheil and Guillaume Walther. (2018). Different modalities of exercise improve macrovascular function but not microvascular function in metabolic syndrome: The RESOLVE randomized trial. International Journal of Cardiology. 267, pp. 165-170. https://doi.org/10.1016/j.ijcard.2018.05.073
Cardiovascular risk of adipokines: A review
Frederic Dutheil, Brett Ashley Gordon, Geraldine Naughton, Edward Crendal, Daniel Courteix, Elodie Chaplais, David Thivel, Gerard Lac and Amanda Benson. (2018). Cardiovascular risk of adipokines: A review. Journal of International Medical Research. 46(6), pp. 2082-2095. https://doi.org/10.1177/0300060517706578
Chronic stress protection for postnatal depression prevention (SERENE): A protocol for an exploratory study
Tharwat, Dahlia, Trousselard, Marion, Balès, Mélanie, Sutter-Dallay, Anne-Laure, Fromage, Dominique, Spitz, Elisabeth, Dallay, Dominique, Harvey, Thierry, Welter, Eric, Coatleven, Frédéric, Cherier, Lydie, Teissèdre, Frédérique, Pouly, Jean-Luc, Dutheil, Frederic and Duffaud, Anaïs M.. (2018). Chronic stress protection for postnatal depression prevention (SERENE): A protocol for an exploratory study. BMJ Open. 8(5), pp. 1 - 8. https://doi.org/10.1136/bmjopen-2017-018317
Work addiction test questionnaire to assess workaholism: Validation of French version
Ravoux, Hortense, Pereira, Bruno, Brousse, Georges, Dewavrin, Samuel, Cornet, Thomas, Mermillod, Martial, Mondillon, Laurie, Vallet, Guillaume, Moustafa, F. and Dutheil, Frederic. (2018). Work addiction test questionnaire to assess workaholism: Validation of French version. Journal of Medical Internet Research. 5(1), pp. 1 - 13. https://doi.org/10.2196/mental.8215
Evidence of rapid modulation by social information of subjective, physiological, and neural responses to emotional expressions
Mermillod, Martial, Grynberg, Delphine, Pio-Lopez, Léo, Rychlowska, Magdalena, Beffara, Brice, Harquel, Sylvain, Vermeulen, Nicolas, Niedenthal, Paula M., Dutheil, Frederic and Droit-Volet, Sylvie. (2018). Evidence of rapid modulation by social information of subjective, physiological, and neural responses to emotional expressions. Frontiers in Behavioral Neuroscience. 11, pp. 1 - 14. https://doi.org/10.3389/fnbeh.2017.00231
Effects of interventions with a physical activity component on bone health in obese children and adolescents: a systematic review and meta-analysis
Elodie, Chaplais, Naughton, Geraldine, Greene, David, Dutheil, Frederic, Pereira, Bruno, Thivel, David and Courteix, Daniel. (2018). Effects of interventions with a physical activity component on bone health in obese children and adolescents: a systematic review and meta-analysis. Journal of Bone and Mineral Metabolism. 36(1), pp. 12 - 30. https://doi.org/10.1007/s00774-017-0858-z
Characteristics and outcomes of reversed patients admitted to an emergency department for VKA-related intramuscular hematoma
Moustafa, F., Poujol, L., Vincent, N., Saint-Denis, Jennifer, Dublanchet, N., Breuil, N., Heuser, S., Lebreton, A., Dutheil, Frederic and Schmidt, Jeannot. (2018). Characteristics and outcomes of reversed patients admitted to an emergency department for VKA-related intramuscular hematoma. American Journal of Emergency Medicine. 36(7), pp. 1257 - 1261. https://doi.org/10.1016/j.ajem.2018.03.067
Incidence of ill-health related job loss and related social and occupational factors. The "unfit for the job" study: a one-year follow-up study of 51,132 workers
Lesage, Francois-Xavier, Dutheil, Frederic, Godderis, Lode, Divies, Aymeric and Choron, Guillaume. (2018). Incidence of ill-health related job loss and related social and occupational factors. The "unfit for the job" study: a one-year follow-up study of 51,132 workers. PeerJ. 2018(6), pp. 1 - 14. https://doi.org/10.7717/peerj.5073
Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX Study
Chaplais, Elodie, Naughton, Geraldine, Dutheil, Frederic, Masurier, Julie, Greene, David, Pereira, Bruno, Duclos, Martine, Thivel, David and Courteix, Daniel. (2018). Geometric and mechanical bone response to a multidisciplinary weight loss intervention in adolescents with obesity: The ADIBOX Study. Journal of Clinical Densitometry. 23(2), pp. 254 - 263. https://doi.org/10.1016/j.jocd.2018.06.002
Influence of uncertainty on framed decision-making with moral dilemma
Merlhiot, Gaëtan, Mermillod, Martial, Pennec, Jean-Luc Le, Dutheil, Frederic and Mondillon, Laurie. (2018). Influence of uncertainty on framed decision-making with moral dilemma. PLoS ONE. 13(5), pp. 1 - 16. https://doi.org/10.1371/journal.pone.0197923
Longitudinal determinants of 12-month changes on bone health in adolescent male athletes
Ubago-Guisado, Esther, Vlachopoulos, Dimitris, Fatouros, Ioannis G., Deli, Chariklia K., Leontsini, Diamanda, Moreno, Luis A., Courteix, Daniel and Gracia-Marco, Luis. (2018). Longitudinal determinants of 12-month changes on bone health in adolescent male athletes. Archives of Osteoporosis. 13(1), pp. 1 - 9. https://doi.org/10.1007/s11657-018-0519-4
Total and regional bone mineral and tissue composition in female adolescent athletes: Comparison between volleyball players and swimmers
Valente-dos-Santos, João, Tavares, Óscar M., Duarte, João P., Sousa-e-Silva, Paulo M., Rama, Luís M., Casanova, José M., Fontes-Ribeiro, Carlos A., Marques, Elisa A., Courteix, Daniel, Ronque, Enio R. V., Cyrino, Edilson S., Conde, Jorge and Coelho-e-Silva, Manuel J.. (2018). Total and regional bone mineral and tissue composition in female adolescent athletes: Comparison between volleyball players and swimmers. BMC Pediatrics. 18(1), pp. 1 - 11. https://doi.org/10.1186/s12887-018-1182-z
Predictive factors of intracranial bleeding in head trauma patients receiving antiplatelet therapy admitted to an emergency department
Moustafa, F., Roubin, Jean, Pereira, Bruno, Barres, Alain, Saint-Denis, Jennifer, Perrier, Christophe, Mondet, Marine, Dutheil, Frederic and Schmidt, Jeannot. (2018). Predictive factors of intracranial bleeding in head trauma patients receiving antiplatelet therapy admitted to an emergency department. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 26(1), pp. 1 - 7. https://doi.org/10.1186/s13049-018-0515-0
Changes in body composition and metabolic profile during interleukin 6 inhibition in rheumatoid arthritis
Tournadre, Anne, Pereira, Bruno, Dutheil, Fréderic, Giraud, Charlotte, Courteix, Daniel, Sapin, Vincent, Frayssac, Thomas, Mathieu, Sylvain, Malochet-Guinamand, Sandrine and Soubrier, Martin. (2017). Changes in body composition and metabolic profile during interleukin 6 inhibition in rheumatoid arthritis. Journal of Cachexia, Sarcopenia and Muscle. 8(4), pp. 639 - 646. https://doi.org/10.1002/jcsm.12189
Assessment of the impact of L-Thyroxine therapy on bleeding risk in patients receiving Vitamin K antagonists
Moustafa, Farès, Malhomme, Rémi, Pereira, Bruno, Barres, Alain, Saint-Denis, Jennifer, Dutheil, Frederic, Batisse, Marie and Schmidt, Jeannot. (2017). Assessment of the impact of L-Thyroxine therapy on bleeding risk in patients receiving Vitamin K antagonists. Clinical Drug Investigation. 37(10), pp. 929 - 936. https://doi.org/10.1007/s40261-017-0545-9
At-risk and intervention thresholds of occupational stress using a visual analogue scale
Dutheil, Frederic, Pereira, Bruno, Moustafa, F., Naughton, Geraldine, Lesage, Francois-Xavier and Lambert, Céline. (2017). At-risk and intervention thresholds of occupational stress using a visual analogue scale. PLoS ONE. 12(6), pp. 1 - 13. https://doi.org/10.1371/journal.pone.0178948
Urine cytology screening of French workers exposed to occupational urinary tract carcinogens: a prospective cohort study over a 20-year period
Dutheil, Frederic, Rouanet, Lucile, Mulliez, Aurélien, Naughton, Geraldine, Fontana, Luc, Druet-Cabanac, Michel, Moustafa, Farès and Chamoux, Alain. (2017). Urine cytology screening of French workers exposed to occupational urinary tract carcinogens: a prospective cohort study over a 20-year period. BMJ Open. 7(9), pp. 1 - 10. https://doi.org/10.1136/bmjopen-2017-016238
Paradoxical dissociation between heart rate and heart rate variability following different modalities of exercise in individuals with metabolic syndrome: The RESOLVE study
Boudet, Gil, Walther, Guillaume, Courteix, Daniel, Obert, Phillippe, Lesourd, Bruno, Pereira, Bruno, Chapier, Robert, Vinet, Agnès, Chamoux, Alain, Naughton, Geraldine, Poirier, Paul and Dutheil, Frédéric. (2017). Paradoxical dissociation between heart rate and heart rate variability following different modalities of exercise in individuals with metabolic syndrome: The RESOLVE study. European Journal of Preventative Cardiology. 24(3), pp. 281 - 296. https://doi.org/10.1177/2047487316679523
Maximal tachycardia and high cardiac strain during night shifts of emergency physicians
Dutheil, Frederic, Marhar, Fouad, Boudet, Gil, Perrier, Christophe, Naughton, Geraldine, Chamoux, Alain, Huguet, P., Mermillod, Martial, Saadaoui, Foued, Moustafa, F. and Schmidt, Jeannot. (2017). Maximal tachycardia and high cardiac strain during night shifts of emergency physicians. International Archives of Occupational and Environmental Health. 90(6), pp. 467 - 480. https://doi.org/10.1007/s00420-017-1211-5
Stress and salivary cortisol in emergency medical dispatchers: A randomized shifts control trial
Bedini, Sarah, Braun, François, Weibel, Laurence, Aussedat, Michel, Pereira, Bruno and Dutheil, Frederic. (2017). Stress and salivary cortisol in emergency medical dispatchers: A randomized shifts control trial. PLoS ONE. 12(5), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0177094
Decreased prevalence of cancer in patients with multiple sclerosis: A case-control study
Moisset, Xavier, Perié, Maud, Pereira, Bruno, Dumont, Emilie, Lebrun-Frenay, Christine, Lesage, Francois-Xavier, Dutheil, Frederic, Taithe, Frederic and Clavelou, Pierre. (2017). Decreased prevalence of cancer in patients with multiple sclerosis: A case-control study. PLoS ONE. 12(11), pp. 1 - 11. https://doi.org/10.1371/journal.pone.0188120
Long-term cost reduction of routine medications following a residential programme combining physical activity and nutrition in the treatment of type 2 diabetes: a prospective cohort study
Lanhers, Charlotte, Walther, Guillaume, Chapier, Robert, Lesourd, Bruno, Naughton, Geraldine, Pereira, Bruno, Duclos, Martine, Vinet, Agnes, Obert, Phillippe, Courteix, Daniel and Dutheil, Frederic. (2017). Long-term cost reduction of routine medications following a residential programme combining physical activity and nutrition in the treatment of type 2 diabetes: a prospective cohort study. BMJ Open. 7(4), pp. 1 - 10. https://doi.org/10.1136/bmjopen-2016-013763
Oxidative and anti-oxidative stress markers in chronic glaucoma : A systematic review and meta-analysis
Benoist d’Azy, Cédric, Pereira, Bruno, Chiambaretta, Frédéric and Dutheil, Frédéric. (2016). Oxidative and anti-oxidative stress markers in chronic glaucoma : A systematic review and meta-analysis. PLoS ONE. 11(12), p. e0166915. https://doi.org/10.1371/journal.pone.0166915
Dysfunctional stress responses in chronic pain
Woda, Alain, Picard, Pascale and Dutheil, Frederic. (2016). Dysfunctional stress responses in chronic pain. Psychoneuroendocrinology. 71, pp. 127 - 135. https://doi.org/10.1016/j.psyneuen.2016.05.017
Antibioprophylaxis in prevention of endophthalmitis in intravitreal injection: A systematic review and meta-analysis
d'Azy, Cédric B., Pereira, Bruno, Naughton, Geraldine A., Chiambaretta, Frédéric and Dutheil, Frederic. (2016). Antibioprophylaxis in prevention of endophthalmitis in intravitreal injection: A systematic review and meta-analysis. PLoS ONE. 11(6), pp. 1 - 12. https://doi.org/10.1371/journal.pone.0156431
Prevalence of dry eye disease in visual display terminal workers: a systematic review and meta-analysis
Courtin, Romain, Pereira, Bruno, Naughton, Geraldine Ann, Chamoux, Alain, Chiambaretta, Frédéric, Lanhers, Charlotte and Dutheil, Frederic. (2016). Prevalence of dry eye disease in visual display terminal workers: a systematic review and meta-analysis. BMJ Open. 6(1), pp. 1 - 8. https://doi.org/10.1136/bmjopen-2015-009675
Ill health-related job loss: A one-year follow-up of 54,026 employees
Dutheil, Frederic, Naughton, Geraldine Ann, Sindyga, Patricia and Lesage, Francois-Xavier. (2016). Ill health-related job loss: A one-year follow-up of 54,026 employees. Journal of Occupational and Environmental Medicine. 58(9), pp. 918 - 923. https://doi.org/10.1097/JOM.0000000000000825
Evaluation of the efficacy and tolerance of a short 7 day third-generation cephalosporin treatment in the management of acute pyelonephritis in young women in the emergency department
Moustafa, Fares, Nguyen, Guillaume, Mathevon, Thierry, Baud, Olivier, Saint-Denis, Jennifer, Dublanchet, Nicolas, Pereira, Bruno, Shinjo, Coralie, Romaszko, Jean-Pierre, Dopeux, Loic, Dutheil, Frederic and Schmidt, Jeannot. (2016). Evaluation of the efficacy and tolerance of a short 7 day third-generation cephalosporin treatment in the management of acute pyelonephritis in young women in the emergency department. Journal of Antimicrobial Chemotherapy. 71(6), pp. 1660 - 1664. https://doi.org/10.1093/jac/dkw021
Concurrent agreement between an anthropometric model to predict thigh volume and dual-energy X-Ray absorptiometry assessment in female volleyball players aged 14-18 years
Tavares, Óscar M., Valente-dos-Santos, João, Duarte, João P., Póvoas, Susana C., Gobbo, Luís A., Fernandes, Rômulo A., Marinho, Daniel Almeida, Casanova, José M., Sherar, Lauren B., Courteix, Daniel and Coelho-e-Silva, Manuel J.. (2016). Concurrent agreement between an anthropometric model to predict thigh volume and dual-energy X-Ray absorptiometry assessment in female volleyball players aged 14-18 years. BMC Pediatrics. 16(190), pp. 1 - 10. https://doi.org/10.1186/s12887-016-0730-7
Are nurses burned out?
Choron, Guillame, Dutheil, Frederic and Lesage, Francois-Xavier. (2016). Are nurses burned out? International Journal of Nursing Studies. 58, pp. 80 - 81. https://doi.org/10.1016/j.ijnurstu.2016.02.002
Validation of the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) in French psychiatric and general populations
Trousselard, Marion, Steiler, Dominique, Dutheil, Frederic, Claverie, Damien, Canini, Frédéric, Fenouillet, Fabien, Naughton, Geraldine Ann, Stewart-Brown, Sarah and Franck, Nicolas. (2016). Validation of the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) in French psychiatric and general populations. Psychiatry Research. 245, pp. 282 - 290. https://doi.org/10.1016/j.psychres.2016.08.050
Stress among nurses working in emergency, anesthesiology and intensive care units depends on qualification: a Job Demand-Control survey
Trousselard, Marion, Dutheil, Frederic, Naughton, Geraldine Ann, Cosserant, Sylvie, Amadon, Sylvie, Christian, Duale and Schoeffler, Pierre. (2016). Stress among nurses working in emergency, anesthesiology and intensive care units depends on qualification: a Job Demand-Control survey. International Archives of Occupational and Environmental Health. https://doi.org/10.1007/s00420-015-1065-7
Cross-sectional and longitudinal study protocols of the 'ADIposity and BOne metabolism: Effects of eXercise-induced weight loss in obese adolescents' (ADIBOX) project
Chaplais, Elodie, Dutheil, Frederic, Naughton, Geraldine Ann, Greene, David Anthony, Pereira, Bruno, Thivel, David and Courteix, Daniel. (2016). Cross-sectional and longitudinal study protocols of the 'ADIposity and BOne metabolism: Effects of eXercise-induced weight loss in obese adolescents' (ADIBOX) project. BMJ Open. 6, pp. 1 - 9. https://doi.org/10.1136/bmjopen-2016-011407
Multilevel approach of a 1-year program of dietary and exercise interventions on bone mineral content and density in metabolic syndrome - the RESOLVE randomized controlled trial
Courteix, Daniel, Valente-dos-Santos, Joao, Ferry, Beatrice, Lac, Gerard, Lesourd, Bruno, Chapier, Robert, Naughton, Geraldine, Marceau, Geoffroy, Coelho-E-Silva, Manuel, Vinet, Agnes, Walther, Guillaume, Obert, Philippe and Dutheil, Frederic. (2015). Multilevel approach of a 1-year program of dietary and exercise interventions on bone mineral content and density in metabolic syndrome - the RESOLVE randomized controlled trial. PLoS One (online). 10(9), pp. 1 - 20. https://doi.org/10.1371/journal.pone.0136491
Creatine supplementation and lower limb strength performance : A systematic review and meta-analyses
Lanhers, Charlotte, Pereira, Bruno, Naughton, Geraldine, Trousselard, Marion, Lesage, Francois-Xavier and Dutheil, Frederic. (2015). Creatine supplementation and lower limb strength performance : A systematic review and meta-analyses. Sports Medicine: reviews of applied medicine and science in sport and exercise. 45(9), pp. 1285 - 1294. https://doi.org/10.1007/s40279-015-0337-4
Electronic cigarettes: The resistance value of the heating filament could be the key to lung toxicity
Chausse, Pierre, Naughton, Geraldine and Dutheil, Frederic. (2015). Electronic cigarettes: The resistance value of the heating filament could be the key to lung toxicity. Chest. 148(1), pp. e29 - e30. https://doi.org/10.1378/chest.15-0497
Bone-adiposity cross-talk: implications for pediatric obesity
Chaplais, Elodie, Thivel, David, Greene, David, Dutheil, Frederic, Duche, Pascale, Naughton, Geraldine and Courteix, Daniel. (2015). Bone-adiposity cross-talk: implications for pediatric obesity. Journal of Bone and Mineral Metabolism. 33(6), pp. 592 - 602. https://doi.org/10.1007/s00774-015-0654-6
Smartphone interventions for weight treatment and behavioral change in pediatric obesity : A systematic review
Chaplais, Elodie, Naughton, Geraldine, Thivel, David, Courteix, Daniel and Greene, David. (2015). Smartphone interventions for weight treatment and behavioral change in pediatric obesity : A systematic review. Telemedicine and e-Health (print). 21(10), pp. 822 - 830. https://doi.org/10.1089/tmj.2014.0197
Metabolic syndrome individuals with and without type 2 diabetes mellitus present generalized vascular dysfunction : Cross-sectional study
Walther, Guillaume, Obert, Philippe, Dutheil, Frederic, Chapier, Robert, Lesourd, Bruno, Naughton, Geraldine, Courteix, Daniel and Vinet, Agnes. (2015). Metabolic syndrome individuals with and without type 2 diabetes mellitus present generalized vascular dysfunction : Cross-sectional study. Arteriosclerosis Thrombosis and Vascular Biology. 35(4), pp. 1022 - 1029. https://doi.org/10.1161/ATVBAHA.114.304591
Chest CT Scan Screening for Lung Cancer in Asbestos Occupational Exposure : A Systematic Review and Meta-analysis
Ollier, Marie, Chamoux, Alain, Naughton, Geraldine, Pereira, Bruno and Dutheil, Frederic. (2014). Chest CT Scan Screening for Lung Cancer in Asbestos Occupational Exposure : A Systematic Review and Meta-analysis. Chest. 145(6), pp. 1339 - 1346. https://doi.org/10.1378/chest.13-2181
Left ventricular myocardial dyssynchrony is already present in nondiabetic patients with metabolic syndrome
Crendal, Edward, Walther, Guillaume, Dutheil, Frederic, Courteix, Daniel, Lesourd, Bruno, Chapier, Robert, Naughton, Geraldine A., Vinet, Agnes and Obert, Phillippe. (2014). Left ventricular myocardial dyssynchrony is already present in nondiabetic patients with metabolic syndrome. Canadian Journal of Cardiology. 30(3), pp. 320 - 324. https://doi.org/10.1016/j.cjca.2013.10.019
Increased myocardial dysfunction, dyssynchrony, and epicardial fat across the lifespan in healthy males
Crendal, Edward, Dutheil, Fred, Naughton, Geraldine, McDonald, Tracey and Obert, Philippe. (2014). Increased myocardial dysfunction, dyssynchrony, and epicardial fat across the lifespan in healthy males. BMC Cardiovascular Disorders. 14(95), pp. 1 - 10. https://doi.org/10.1186/1471-2261-14-95
Atherogenic subfractions of lipoproteins in the treatment of metabolic syndrome by physical activity and diet - the RESOLVE trial
Dutheil, Frederic, Walther, Guillame, Chapier, Robert, Mnatzaganian, George, Lesourd, Bruno, Naughton, Geraldine, Verney, Julien, Fogli, Anne, Sapin, Vincent, Duclos, Martine, Vinet, Agnes, Obert, Philippe, Courteix, Daniel and Lac, Gerard. (2014). Atherogenic subfractions of lipoproteins in the treatment of metabolic syndrome by physical activity and diet - the RESOLVE trial. Lipids in Health and Disease. 13(1). https://doi.org/10.1186/1476-511X-13-112
Comparison of the ultra-low-dose Veo algorithm with the gold standard filtered back projection for detecting pulmonary asbestos-related conditions : A clinical observational study
Tekath, Marielle, Dutheil, Frederic, Bellini, Romain, Roche, Antoine, Pereira, Bruno, Naughton, Geraldine, Chamoux, Alain and Michel, Jean-Luc. (2014). Comparison of the ultra-low-dose Veo algorithm with the gold standard filtered back projection for detecting pulmonary asbestos-related conditions : A clinical observational study. BMJ Open. 4(5), pp. 1 - 8. https://doi.org/10.1136/bmjopen-2014-004980
Right ventricle free wall mechanics in metabolic syndrome without type-2 diabetes: Effects of a 3-month lifestyle intervention program
Serrano-Ferrer, Juan, Walther, Guillaume, Crendal, Edward, Vinet, Agnes, Dutheil, Frederic, Naughton, Geraldine A., Lesourd, Bruno, Chapier, Robert, Courteix, Daniel and Obert, Philippe. (2014). Right ventricle free wall mechanics in metabolic syndrome without type-2 diabetes: Effects of a 3-month lifestyle intervention program. Cardiovascular Diabetology. 13(1), pp. 1 - 11. https://doi.org/10.1186/s12933-014-0116-9
Atherogenic subfractions of lipoproteins in the treatment of metabolic syndrome by physical activity and diet : the RESOLVE trial
Dutheil, Frederic, Walther, Guillaume, Chapier, Robert, Mnatzaganian, George, Lesourd, Bruno, Naughton, Geraldine, Verney, Julien, Fogli, Anne, Sapin, Vincent and Duclose, Martine. (2014). Atherogenic subfractions of lipoproteins in the treatment of metabolic syndrome by physical activity and diet : the RESOLVE trial. Lipids in Health and Disease. 13(112), pp. 1 - 9. https://doi.org/10.1186/1476-511X-13-112
Myocardial deformation and twist mechanics in adults with metabolic syndrome : Impact of cumulative metabolic burden
Crendal, Edward, Walther, Guillaume, Vinet, Agnes, Dutheil, Frederic, Naughton, Geraldine, Lesourd, Bruno, Chapier, Robert, Rupp, Thomas, Courteix, Daniel and Obert, Philippe. (2013). Myocardial deformation and twist mechanics in adults with metabolic syndrome : Impact of cumulative metabolic burden. Obesity: a resourch journal. https://doi.org/10.1002/oby.20537
Urinary Interleukin-8 is a biomarker of stress in emergency physicians, especially with advancing age: The JOBSTRESS* randomized trial
Dutheil, Frederic, Trousselard, Marion, Perrier, Christophe, Lac, Gerard, Chamoux, Alain, Duclos, Martine, Naughton, Geraldine, Mnatzaganian, George and Schmidt, Jeannot. (2013). Urinary Interleukin-8 is a biomarker of stress in emergency physicians, especially with advancing age: The JOBSTRESS* randomized trial. PLoS ONE. 8(8), pp. 1 - 7. https://doi.org/10.1371/journal.pone.0071658
Gymnastics participation is associated with skeletal benefits in the distal forearm : a 6-month study using peripheral Quantitative Computed Tomography
Burt, Lauren, Ducher, Gaele, Naughton, Geraldine, Courteix, Daniel and Greene, David. (2013). Gymnastics participation is associated with skeletal benefits in the distal forearm : a 6-month study using peripheral Quantitative Computed Tomography. The Journal of Musculoskeletal and Neuronal Interactions.
Different modalities of exercise to reduce visceral fat mass and cardiovascular risk in metabolic syndrome : the RESOLVE* randomized trial
Dutheil, Frederic, Lac, Gerard, Lesourd, Bruno, Chapier, Robert, Walther, Guillaume, Vinet, Agnes, Sapin, Vincent, Verney, Julien, Ouchchane, Lemlih and Duclos, Martine. (2013). Different modalities of exercise to reduce visceral fat mass and cardiovascular risk in metabolic syndrome : the RESOLVE* randomized trial. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2013.05.012
The long-term effects of occupational exposure to vinyl chloride monomer on microcirculation : a cross-sectional study 15 years after retirement
Lopez, Vincent, Chamoux, Alain, Tempier, Marion, Thiel, Helene, Ughetto, Sylvie, Trousselard, Marion, Naughton, Geraldine and Dutheil, Frederic. (2013). The long-term effects of occupational exposure to vinyl chloride monomer on microcirculation : a cross-sectional study 15 years after retirement. BMJ Open. https://doi.org/10.1136/bmjopen-2013-002785
Non-elite gymnastics participation is associated with greater bone strength, muscle size, and function in pre- and early pubertal girls
Burt, Lauren, Naughton, Geraldine, Greene, David and Courteix, Daniel. (2012). Non-elite gymnastics participation is associated with greater bone strength, muscle size, and function in pre- and early pubertal girls. Osteoporosis International. 23(4), pp. 1277 - 1286. https://doi.org/10.1007/s00198-011-1677-z
Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial
Dutheil, Frederic, Lac, Gerard, Courteix, Daniel, Dore, Eric, Chapier, Robert, Roszyk, Laurence, Sapin, Vincent and Lesourd, Bruno. (2012). Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial. Nutrition Journal. 11(1). https://doi.org/10.1186/1475-2891-11-72
Bone geometry and strength adaptations to physical constraints inherent in different sports: Comparison between elite female soccer players and swimmers
Ferry, B., Duclos, M., Burt, Lauren A., Therre, P., Le Gall, F., Jaffré, C. and Courteix, D.. (2011). Bone geometry and strength adaptations to physical constraints inherent in different sports: Comparison between elite female soccer players and swimmers. Journal of Bone and Mineral Metabolism (print version). 29(3), pp. 342 - 351. https://doi.org/10.1007/s00774-010-0226-8
Bone geometry and strength adaptations to physical constraints inherent in different sports: comparison between elite female soccer players and swimmers
Ferry, Beatrice, Duclos, Martine, Burt, Lauren, Therre, Perrine, Le Gall, Franck, Jaffre, Christelle and Courteix, Daniel. (2011). Bone geometry and strength adaptations to physical constraints inherent in different sports: comparison between elite female soccer players and swimmers. Journal of Bone and Mineral Metabolism. 29(3). https://doi.org/10.1007/s00774-010-0226-8
Effect of a six-month training programme on the physical capacities of Romanian schoolchildren
Greene, David, Serbescu, Carmen, Flora, D., Hantiu, Iacob, Benhamou, Claude Laurent and Courteix, Daniel. (2006). Effect of a six-month training programme on the physical capacities of Romanian schoolchildren. Acta Paediatrica. 10(10), pp. 1258 - 1265. https://doi.org/10.1080/08035250600599719