Centre for Exercise and Nutrition


TypeDepartment
FacultyFaculty of Health Sciences

Latest research outputs

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Circulating and adipose tissue miRNAs in women with polycystic ovary syndrome and responses to high-intensity interval training
Lionett,Sofie, Kiel,Ida A., Camera,Donny M., Vanky,Eszter, Parr, E., Lydersen,Stian, Hawley, J. and Moholdt,Trine. (2020). Circulating and adipose tissue miRNAs in women with polycystic ovary syndrome and responses to high-intensity interval training. Frontiers in Physiology. 11, p. 904. https://doi.org/10.3389/fphys.2020.00904

Journal article

Casein ingestion does not increase muscle connective tissue protein synthesis rates
Trommelen, Jorn, Holwerda, Andrew M., Senden, Joan M., Goessens, Joy P. B., Van Kranenburg, Janneau, Gijsen, Annemie P., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Casein ingestion does not increase muscle connective tissue protein synthesis rates. Medicine & Science in Sports & Exercise. 52(9), pp. 1983-1991. https://doi.org/10.1249/MSS.0000000000002337

Journal article

A multi-parametric approach to remove the influence of plasma volume on the athlete biological passport during a Union Cycliste Internationale cycling stage race
Lewis, Laura, Lobigs, Louisa M., Equey, Tristan, Goebel, Catrin, Agon, Vanessa, McCowan, Andrew, Speers, Naomi and Schumacher, Yorck. (2020). A multi-parametric approach to remove the influence of plasma volume on the athlete biological passport during a Union Cycliste Internationale cycling stage race. Drug Testing and Analysis. 12(9), pp. 1252-1263. https://doi.org/10.1002/dta.2878

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Combined effects of continuous exercise and intermittent active interruptions to prolonged sitting on postprandial glucose, insulin, and triglycerides in adults with obesity : A randomized crossover trial
Wheeler, Michael J., Green, Daniel J., Cerin, Ester, Ellis, Kathryn A., Heinonen, Ilkka, Lewis, Jaye, Naylor, Louise H., Cohen, Neale, Larsen, Robyn, Dempsey, Paddy C., Kingwell, Bronwyn A., Owen, Neville and Dunstan, David W.. (2020). Combined effects of continuous exercise and intermittent active interruptions to prolonged sitting on postprandial glucose, insulin, and triglycerides in adults with obesity : A randomized crossover trial. International Journal of Behavioral Nutrition and Physical Activity. 17(1), p. 152. https://doi.org/10.1186/s12966-020-01057-9

Journal article

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Langendorf, Christopher G., O'Brien, Matthew T., Ngoei, Kevin R. W., McAloon, Luke M., Dhagat, Urmi, Hoque, Ashfaqul, Ling, Naomi X. Y., Dite, Toby A., Galic, Sandra, Loh, Kim, Parker, Michael W., Oakhill, Jonathan S., Kemp, Bruce E. and Scott, John W.. (2020). CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins. Journal of Biological Chemistry. 295(48), pp. 16239-16250. https://doi.org/10.1074/jbc.RA120.013756

Journal article

Topical sodium bicarbonate : No improvement in blood buffering capacity or exercise performance
McKay, Alannah K. A., Peeling, Peter, Binnie, Martyn J., Goods, Paul S. R., Sim, Marc, Cross, Rebecca and Siegler, Jason. (2020). Topical sodium bicarbonate : No improvement in blood buffering capacity or exercise performance. International Journal of Sports Physiology and Performance. 15(7), pp. 1005-1011. https://doi.org/10.1123/ijspp.2019-0345

Journal article

The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKa2
Lee, Jung Ok, Byun, Won Seok, Kang, Min Ju, Han, Jeong Ah, Moon, Jiyoung, Shin, Min-Jeong, Lee, Ho Jun, Chung, Ji Hyung, Lee, Jin-Seok, Son, Chang-Gue, Song, Kwon-Ho, Kim, Tae Woo, Lee, Eun-Soo, Kim, Hong Min, Chung, Choon Hee, Ngoei, Kevin R. W., Ling, Naomi X. Y., Oakhill, Jonathan S., Galic, Sandra, ... Kim, Hyeon Soo. (2020). The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKa2. The FEBS Journal. 287(10), pp. 2087-2104. https://doi.org/10.1111/FEBS.15301

Journal article

The glycation level of milk protein strongly modulates post-prandial lysine availability in humans
Nyakayiru, Jean, van Lieshout, Glenn A. A., Trommelen, Jorn, van Kranenburg, Janneau, Verdijk, Lex B., Bragt, Marjolijn C. E. and van Loon, Luc J. C.. (2020). The glycation level of milk protein strongly modulates post-prandial lysine availability in humans. British Journal of Nutrition. 123(5), pp. 545-552. https://doi.org/10.1017/S0007114519002927

Journal article

The effect of sleep restriction, with or without high-intensity interval exercise, on myofibrillar protein synthesis in healthy young me
Saner, Nicholas J., Lee, Matthew J.-C., Pitchford, Nathan W., Kuang, Jujiao, Roach, Gregory D., Garnham, Andrew, Stokes, Tanner, Phillips, Stuart M., Bishop, David J. and Bartlett, Jonathan D.. (2020). The effect of sleep restriction, with or without high-intensity interval exercise, on myofibrillar protein synthesis in healthy young me. The Journal of Physiology. 598(8), pp. 1523-1536. https://doi.org/10.1113/JP278828

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The concept of skeletal muscle memory : Evidence from animal and human studies
Snijders, Tim, Aussieker, Thorben, Holwerda, Andy, Parise, Gianni, van Loon, Luc J. C. and Verdijk, Lex B.. (2020). The concept of skeletal muscle memory : Evidence from animal and human studies. Acta Physiologica. 229(3), pp. 1-20. https://doi.org/10.1111/apha.13465

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Temporal muscle-specific disuse atrophy during one week of leg immobilization
Kilroe, Sean P., Fulford, Jonathan, Jackman, Sarah R., van Loon, Luc J. C. and Wall, Benjamin T.. (2020). Temporal muscle-specific disuse atrophy during one week of leg immobilization. Medicine & Science in Sports & Exercise. 52(4), pp. 944-954. https://doi.org/10.1249/MSS.0000000000002200

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Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission
Dirks, Marlou L., Miotto, Paula M., Goossens, Gijs H., Senden, Joan M., Petrick, Heather L., van Kranenburg, Janneau, van Loon, Luc J. C. and Holloway, Graham P.. (2020). Short-term bed rest-induced insulin resistance cannot be explained by increased mitochondrial H2O2 emission. The Journal of Physiology. 598(1), pp. 123-137. https://doi.org/10.1113/JP278920

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Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans
Gorissen, Stefan H. M., Trommelen, Jorn, Kouw, Imre W. K., Holwerda, Andrew M., Pennings, Bart, Groen, Bart B. L., Wall, Benjamin T., Churchward-Venne, Tyler A., Horstman, Astrid M. H., Koopman, René, Burd, Nicholas A., Fuchs, Cas J., Dirks, Marlou L., Res, Peter T., Senden, Joan M. G., Steijns, Jan M. J. M., de Groot, Lisette C. P. G. M., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Protein type, protein dose, and age modulate dietary protein digestion and phenylalanine absorption kinetics and plasma phenylalanine availability in humans. The Journal of Nutrition. 150(8), pp. 2041-2050. https://doi.org/10.1093/jn/nxaa024

Journal article

Postexercise cooling impairs muscle protein synthesis rates in recreational athletes
Fuchs, Cas J., Kouw, Imre W. K., Churchward-Venne, Tyler A., Smeets, Joey S. J., Senden, Joan M., Lichtenbelt, Wouter D. van Marken, Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. The Journal of Physiology. 598(4), pp. 755-772. https://doi.org/10.1113/JP278996

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Omega-3 polyunsaturated fatty acids mitigate palmitate-induced impairments in skeletal muscle cell viability and differentiation
Tachtsis, Bill, Whitfield, Jamie, Hawley, John A. and Hoffman, Nolan J.. (2020). Omega-3 polyunsaturated fatty acids mitigate palmitate-induced impairments in skeletal muscle cell viability and differentiation. Frontiers in Physiology. 11, pp. 1-13. https://doi.org/10.3389/fphys.2020.00563

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The Challenge of Maintaining Metabolic Health During a Global Pandemic
Andy J. King, Louise M. Burke, Shona L. Halson and John A. Hawley. (2020). The Challenge of Maintaining Metabolic Health During a Global Pandemic. Sports Medicine. 50(7), pp. 1233-1241. https://doi.org/10.1007/s40279-020-01295-8

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Sports Dietitians Australia Position Statement: Nutrition for Exercise in Hot Environments
Alan J McCubbin, Bethanie A Allanson, Joanne N Caldwell Odgers, Michelle M Cort, Ricardo J S Costa, Gregory R. Cox, Siobhan Crawshay, Ben Desbrow, Eliza G Freney, Stephanie K Gaskell, David Hughes, Chris Irwin, Ollie Jay, Benita Lalor, Meg Ross, Gregory Shaw, Julien Periard and Louise Burke. (2020). Sports Dietitians Australia Position Statement: Nutrition for Exercise in Hot Environments. International Journal of Sport Nutrition and Exercise Metabolism. 30(1), pp. 83-98. https://doi.org/10.1123/ijsnem.2019-0300

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Mitochondrial respiration variability and simulations in human skeletal muscle : The Gene SMART study
Jacques, Macsue, Kuang, Jujiao, Bishop, David J., Yan, Xu, Alvarez-Romero, Javier, Munson, Fiona, Garnham, Andrew, Papadimitriou, Ioannis, Voisin, Sarah and Eynon, Nir. (2020). Mitochondrial respiration variability and simulations in human skeletal muscle : The Gene SMART study. The FASEB Journal. 34(2), pp. 2978-2986. https://doi.org/10.1096/fj.201901997RR

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Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise
Ian Rollo, Javier T. Gonzalez, Cas J. Fuchs, Lucas Van Loon and Clyde Williams. (2020). Primary, Secondary, and Tertiary Effects of Carbohydrate Ingestion During Exercise. Sports Medicine. 50(11), pp. 1863-1871. https://doi.org/10.1007/s40279-020-01343-3

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PRESENT 2020: Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials
James A. Betts, Javier T. Gonzalez, Louise Burke, Graeme L. Close, Ina Garthe, Lewis J James, Asker E Jeukendrup, James P. Morton, David C Nieman, Peter Peeling, Stuart M Phillips, Trent Stellingwerff, Lucas Van Loon, Clyde Williams, Kathleen Woolf, Ronald J. Maughan and Greg Atkinson. (2020). PRESENT 2020: Text Expanding on the Checklist for Proper Reporting of Evidence in Sport and Exercise Nutrition Trials. International Journal of Sport Nutrition and Exercise Metabolism. 30(1), pp. 2-13. https://doi.org/10.1123/ijsnem.2019-0326

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Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool
Henver S Brunetta, Andrew M Holwerda, Luc Van Loon and Graham P Holloway. (2020). Mitochondrial ROS and Aging: Understanding Exercise as a Preventive Tool. Journal of Science in Sport and Exercise. 2, pp. 15-24. https://doi.org/10.1007/s42978-019-00037-1

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Improving reproductive function in women with polycystic ovary syndrome with high-intensity interval training (IMPROV-IT): study protocol for a two-centre, three-armed randomised controlled trial
Ida Almenning Kiel, Sofie Lionett, Evelyn Parr, Helen Jones, Maria Aurora Hernandez Roset, Oyvind Salvesen, Eszter Vanky and Trine Moholdt. (2020). Improving reproductive function in women with polycystic ovary syndrome with high-intensity interval training (IMPROV-IT): study protocol for a two-centre, three-armed randomised controlled trial. BMJ Open. 10(2), pp. 1-9. https://doi.org/10.1136/bmjopen-2019-034733

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Implementing Exercise in Healthcare Settings: The Potential of Implementation Science
Louise Czosnek, Nicole Rankin, Eva Zopf, Justin Richards, Simon Rosenbaum and Prue Cormie. (2020). Implementing Exercise in Healthcare Settings: The Potential of Implementation Science. Sports Medicine. 50, pp. 1-14. https://doi.org/10.1007/s40279-019-01228-0

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Key viral immune genes and pathways identify elite athletes with URS
Colbey, Candice, Drew, Michael K., Cox, Amanda J., Vider, Jelena, Pyne, David B., Vlahovich, Nicole, Hughes, David, Waddington, Gordon, Appaneal, Renee, Burke, Louise M., Lundy, Bronwen, Toomey, Mary, Watts, David, Lovell, Gregory, Praet, Stephan, Halson, Shona L., Welvaert, Marijke, Zhang, Ping, Cripps, Allan W. and West, Nicholas P. (2020). Key viral immune genes and pathways identify elite athletes with URS. Exercise Immunology Review. 26, pp. 56-78.

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Impact of whole dairy matrix on musculoskeletal health and aging–current knowledge and research gaps
N.R.W. Geiker, C. Mølgaard, S. Iuliano, R. Rizzoli, Y. Manios, L.J.C. van Loon, J.-M. Lecerf, G. Moschonis, J.-Y. Reginster, I. Givens and A. Astrup. (2020). Impact of whole dairy matrix on musculoskeletal health and aging–current knowledge and research gaps. Osteoporosis International. 31(4), pp. 601-615. https://doi.org/10.1007/s00198-019-05229-7

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Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest
Gonzalez, Javier T., Dirks, Marlou L., Holwerda, Andrew M., Kouw, Imre W. K. and van Loon, Luc J. C.. (2020). Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest. European Journal of Applied Physiology. 120, pp. 2083-2094. https://doi.org/10.1007/s00421-020-04431-4

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Inflammation and oral contraceptive use in female athletes before the Rio Olympic Games
Larsen, Brianna, Cox, Amanda, Colbey, Candice, Drew, Michael, McGuire, Helen, Fazekas de St Groth, Barbara, Hughes, David, Vlahovich, Nicole, Waddington, Gordon, Burke, Louise, Lundy, Bronwen, West, Nicholas and Minahan, Clare. (2020). Inflammation and oral contraceptive use in female athletes before the Rio Olympic Games. Frontiers in Physiology. 11, pp. 1-8. https://doi.org/10.3389/fphys.2020.00497

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Exploring the mechanisms by which nitrate supplementation improves skeletal muscle contractile function: one fibre at a time
Luke C. McIlvenna, David J. Muggeridge and Jamie Whitfield. (2020). Exploring the mechanisms by which nitrate supplementation improves skeletal muscle contractile function: one fibre at a time. The Journal of Physiology. 598(1), pp. 25-27. https://doi.org/10.1113/Jp279118

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Exercise medicine in cancer care
Prue Cormie, Mark Trevaskis, Elysia Thornton-Benko and Eva M Zopf. (2020). Exercise medicine in cancer care. Australian Journal of General Practice. 49(4), pp. 169-174. https://doi.org/10.31128/AJGP-08-19-5027

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Impact of exercise-nutritional state interactions in patients with type 2 diabetes
Verboven, Kenneth, Wens, Inez, Vandenabeele, Frank, Stevens, An, Celie, Bert, Lapauw, Bruno, Dendale, Paul, van Loon, Luc J. C., Calders, Patrick and Hansen, Dominique. (2020). Impact of exercise-nutritional state interactions in patients with type 2 diabetes. Medicine and Science in Sports and Exercise. 52(3), pp. 720-728. https://doi.org/10.1249/MSS.0000000000002165

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Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review
Jean Nyakayiru, Luc Van Loon and Lex B. Verdijk. (2020). Could intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review. Free Radical Biology & Medicine. 152, pp. 295-300. https://doi.org/10.1016/j.freeradbiomed.2020.03.025

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Hot-water immersion does not increase postprandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males
Fuchs, Cas J., Smeets, Joey S. J., Senden, Joan M., Zorenc, Antoine H., Goessens, Joy P. B., van Marken Lichtenbelt, Wouter D., Verdijk, Lex B. and van Loon, Luc J. C.. (2020). Hot-water immersion does not increase postprandial muscle protein synthesis rates during recovery from resistance-type exercise in healthy, young males. Journal of Applied Physiology. 128(4), pp. 1012-1022. https://doi.org/10.1152/japplphysiol.00836.2019

Journal article

A time to eat and a time to exercise
Parr, Evelyn B., Heilbronn, Leonie K. and Hawley, John A.. (2020). A time to eat and a time to exercise. Exercise and Sport Sciences Reviews. 48(1), pp. 4-10. https://doi.org/10.1249/JES.0000000000000207

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Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism
Hoffman, Nolan J., Whitfield, Jamie, Janzen, Natalie R., Belhaj, Mehdi R., Galic, Sandra, Murray-Segal, Lisa, Smiles, William J., Ling, Naomi X. Y., Dite, Toby A., Scott, John W., Oakhill, Jonathan S., Brink, Robert, Kemp, Bruce E. and Hawley, John A.. (2020). Genetic loss of AMPK-glycogen binding destabilizes AMPK and disrupts metabolism. Molecular Metabolism. 41, pp. 1-13. https://doi.org/10.1016/j.molmet.2020.101048

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Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms
Pinkosky, Stephen L., Scott, John W., Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ford, Rebecca J., Langendorf, Christopher G., Ling, Naomi X. Y., Nero, Tracy L., Loh, Kim, Galic, Sandra, Hoque, Ashfaqul, Smiles, William J., Ngoei, Kevin R. W., Parker, Michael W., Yan, Yan, Melcher, Karsten, Kemp, Bruce E., Oakhill, Jonathan S. and Steinberg, Gregory R.. (2020). Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms. Nature Metabolism. 2(9), pp. 873-881. https://doi.org/10.1038/s42255-020-0245-2

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Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression
Leonidas S Lundell, Evelyn Parr, Brooke Devlin, Lars R Ingerslev, Ali Altintas, Shogo Sato, Paolo Sassone-Corsi, Romain Barres, Juleen R Zierath and John Hawley. (2020). Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression. Nature Communications. 11(1), pp. 1-11. https://doi.org/10.1038/s41467-020-18412-w

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Validity and reliability evidence of a point of care assessment of salivary cortisol and a-amylase: a pre-registered study
Kagan J. Ducker, Robin L.J. Lines, Michael T. Chapman, Peter Peeling, Alannah K.A. McKay and Daniel F. Gucciardi. (2020). Validity and reliability evidence of a point of care assessment of salivary cortisol and a-amylase: a pre-registered study. PeerJ. 8(e8366). https://doi.org/10.7717/peerj.8366

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Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats
Holwerda, Andrew M., Bouwman, Freek G., Nabben, Miranda, Wang, Ping, van Kranenburg, Janneau, Gijsen, Annemie P., Burniston, Jatin G., Mariman, Edwin C. M. and van Loon, Luc J. C.. (2020). Endurance-type exercise increases bulk and individual mitochondrial protein synthesis rates in rats. International Journal of Sport Nutrition and Exercise Metabolism. 30(2), pp. 153-164. https://doi.org/10.1123/ijsnem.2019-0281

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End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis
Hendriks, Floris K., Smeets, Joey S. J., Broers, Natascha J. H., van Kranenburg, Janneau M. X., van der Sande, Frank M., Kooman, Jeroen P. and van Loon, Luc J. C.. (2020). End-stage renal disease patients lose a substantial amount of amino acids during hemodialysis. The Journal of Nutrition. 150(5), pp. 1160-1166. https://doi.org/10.1093/jn/nxaa010

Journal article

Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue
Hussain, Nusrat, Chuang, Sheng-Ju, Johanns, Manuel, Vertommen, Didier, Steinberg, Gregory R., Kemp, Bruce E. and Rider, Mark H.. (2020). Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue. Biochemical Journal. 477(8), pp. 1373-1389. https://doi.org/10.1042/BCJ20190788

Journal article

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