Chronic pantothenic acid supplementation does not affect muscle coenzyme A content or cycling performance
Journal article
Whitfield, Jamie, Harris, Roger C., Broad, Elizabeth M., Patterson, Alison K., Ross, Megan L. R., Shaw, Gregory, Spriet, Lawrence L. and Burke, Louise M.. (2021). Chronic pantothenic acid supplementation does not affect muscle coenzyme A content or cycling performance. Applied Physiology, Nutrition and Metabolism. 46(3), pp. 280-283. https://doi.org/10.1139/apnm-2020-0692
Authors | Whitfield, Jamie, Harris, Roger C., Broad, Elizabeth M., Patterson, Alison K., Ross, Megan L. R., Shaw, Gregory, Spriet, Lawrence L. and Burke, Louise M. |
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Abstract | [English] This study determined if supplementation with pantothenic acid (PA) for 16 weeks could increase skeletal muscle coenzyme A (CoASH) content and exercise performance. Trained male cyclists (n = 14) were matched into control or PA (6 g·day1) groups. At 0, 4, 8, and 16 weeks, subjects performed an incremental time to exhaustion cycle with muscle biopsies taken prior to and following exercise. Prolonged PA supplementation did not change skeletal muscle CoASH and acetyl- CoA contents or exercise performance. Novelty: Supplementation with pantothenic acid for 16 weeks had no effect on skeletal muscle CoASH and acetyl-CoA content or exercise performance in trained male cyclists. [French] Cette étude détermine si une supplémentation en acide pantothénique (« PA ») pendant 16 semaines peut augmenter la teneur en coenzyme A (« CoASH ») du muscle squelettique et la performance à l’exercice. Les cyclistes masculins entraînés (n = 14) sont appariés dans des groupes témoins ou PA (6 g·jour−1). Aux semaines 0, 4, 8 et 16, les sujets effectuent un exercice incrémental de pédalage au cours duquel on mesure la durée jusqu’à épuisement ; des biopsies musculaires sont prélevées avant et après l’exercice. Une supplémentation prolongée en PA ne modifie pas les teneurs en CoASH et en acétyl-CoA du muscle squelettique ni la performance à l’exercice. [Traduit par la Rédaction] |
Keywords | acetyl-CoA; coenzyme A; exercise performance; skeletal Muscle |
Year | 2021 |
Journal | Applied Physiology, Nutrition and Metabolism |
Journal citation | 46 (3), pp. 280-283 |
Publisher | Canadian Science Publishing |
ISSN | 17155312 |
Digital Object Identifier (DOI) | https://doi.org/10.1139/apnm-2020-0692 |
Scopus EID | 2-s2.0-85102184282 |
Research or scholarly | Research |
Page range | 280-283 |
Publisher's version | License All rights reserved File Access Level Controlled |
Output status | Published |
Publication dates | |
Online | 19 Oct 2020 |
Publication process dates | |
Deposited | 26 Mar 2021 |
https://acuresearchbank.acu.edu.au/item/8v948/chronic-pantothenic-acid-supplementation-does-not-affect-muscle-coenzyme-a-content-or-cycling-performance
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