Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for Stroke prevention in atrial fibrillation
Journal article
Wallentin, Lars, Lopes, Renato D., Hanna, Michael, Thomas, Laine, Hellkamp, Anne, Nepal, Sunil, Hylek, Elaine, Al-Khatib, Sana M., Alexander, John H., Alings, Marco, Amerena, John, Ansell, Jack, Aylward, Philip, Bartunek, Jozef, Commerford, Patrick, De Caterina, Raffaele, Erol, Çetin, Harjola, Veli-Pekka, Held, Claes, ... Granger, Christopher B.. (2013). Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for Stroke prevention in atrial fibrillation. Circulation. 127(22), pp. 2166 - 2176. https://doi.org/10.1161/CIRCULATIONAHA.112.142158
Authors | Wallentin, Lars, Lopes, Renato D., Hanna, Michael, Thomas, Laine, Hellkamp, Anne, Nepal, Sunil, Hylek, Elaine, Al-Khatib, Sana M., Alexander, John H., Alings, Marco, Amerena, John, Ansell, Jack, Aylward, Philip, Bartunek, Jozef, Commerford, Patrick, De Caterina, Raffaele, Erol, Çetin, Harjola, Veli-Pekka, Held, Claes, Horowitz, John, Huber, Kurt, Husted, Steen, Keltai, Matyas, Lanas, Fernando, Lisheng, Liu, McMurray, John, Oh, Byung Hee, Rosenqvist, Mårten, Ruzyllo, Witold, Steg, Philippe Gabriel, Vinereanu, Dragos, Xavier, Denis and Granger, Christopher B. |
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Abstract | In the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial, apixaban compared with warfarin reduced stroke and systemic embolism, major bleeding, and mortality. We evaluated treatment effects in relation to 2 predictions of time in therapeutic range (TTR). |
Keywords | anticoagulation; apixaban; atrial fibrillation; bleeding; stroke; warfarin |
Year | 2013 |
Journal | Circulation |
Journal citation | 127 (22), pp. 2166 - 2176 |
Publisher | Lippincott Williams & Wilkins |
ISSN | 0009-7322 |
Digital Object Identifier (DOI) | https://doi.org/10.1161/CIRCULATIONAHA.112.142158 |
Scopus EID | 2-s2.0-84878535107 |
Open access | Open access |
Page range | 2166 - 2176 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | |
Place of publication | United States |
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https://acuresearchbank.acu.edu.au/item/8qw4w/efficacy-and-safety-of-apixaban-compared-with-warfarin-at-different-levels-of-predicted-international-normalized-ratio-control-for-stroke-prevention-in-atrial-fibrillation
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