Baseline characteristics and temporal differences in acarbose cardiovascular evaluation (ACE) trial participants
Journal article
Theodorakis, Michael J., Coleman, Ruth L., Feng, Huimei, Chan, Juliana, Chiasson, Jean Louis, Ge, Junbo, Gerstein, Hertzel C., Huo, Yong, Lang, Zhihui, McMurray, John, Rydén, Lars E., Schröder, Stefan, Tendera, Michal, Tuomilehto, J., Yang, Wenying, Hu, Dayi, Pan, Changyu and Holman, Rury R.. (2018). Baseline characteristics and temporal differences in acarbose cardiovascular evaluation (ACE) trial participants. American Heart Journal. 199, pp. 170 - 175. https://doi.org/10.1016/j.ahj.2017.09.001
Authors | Theodorakis, Michael J., Coleman, Ruth L., Feng, Huimei, Chan, Juliana, Chiasson, Jean Louis, Ge, Junbo, Gerstein, Hertzel C., Huo, Yong, Lang, Zhihui, McMurray, John, Rydén, Lars E., Schröder, Stefan, Tendera, Michal, Tuomilehto, J., Yang, Wenying, Hu, Dayi, Pan, Changyu and Holman, Rury R. |
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Abstract | The ACE trial is examining whether acarbose, an insulin-sparing postprandial glucose-lowering agent, can reduce cardiovascular (CV) events in patients who have coronary heart disease (CHD) and impaired glucose tolerance (IGT), with prevention of type 2 diabetes (T2D) as a secondary outcome.1., 2. This update report evaluates the impact of the protocol-driven 4-week CV risk management optimization strategy during the run-in period, lists participant baseline characteristics, and examines whether temporal differences occurred during the 7-year recruitment period. |
Year | 2018 |
Journal | American Heart Journal |
Journal citation | 199, pp. 170 - 175 |
Publisher | Elsevier - Mosby |
ISSN | 0002-8703 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.ahj.2017.09.001 |
Scopus EID | 2-s2.0-85032150802 |
Page range | 170 - 175 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United States of America |
Editors | D. B. Mark |
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