Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial
Journal article
Abualnaja, Seraj, Podder, Mohua, Hernandez, Adrian F., McMurray, John J.V., Starling, Randall C., O'Connor, Christopher M., Califf, Robert M., Armstrong, Paul W. and Ezekowitz, Justin A.. (2015). Acute Heart Failure and Atrial Fibrillation: Insights From the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) Trial. Journal of the American Heart Association. 4(8), pp. 1 - 8. https://doi.org/10.1161/JAHA.115.002092
Authors | Abualnaja, Seraj, Podder, Mohua, Hernandez, Adrian F., McMurray, John J.V., Starling, Randall C., O'Connor, Christopher M., Califf, Robert M., Armstrong, Paul W. and Ezekowitz, Justin A. |
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Abstract | Background-—Patients with acute heart failure (AHF) frequently have atrial fibrillation (AF), but how this affects patient-reported outcomes has not been well characterized. Methods and Results-—We examined dyspnea improvement and clinical outcomes in 7007 patients in the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure (ASCEND-HF) trial. At baseline, 2677 (38.2%) patients had current or a history of AF and 4330 (61.8%) did not. Patients with a history of AF were older than those without (72 vs. 63 years) and had more comorbidities and a higher median left ventricular ejection fraction (31% vs. 27%, P |
Keywords | acute heart failure; atrial fibrillation; clinical trials; outcome |
Year | 2015 |
Journal | Journal of the American Heart Association |
Journal citation | 4 (8), pp. 1 - 8 |
Publisher | Wiley-Blackwell Publishing, Inc. |
ISSN | 2047-9980 |
Digital Object Identifier (DOI) | https://doi.org/10.1161/JAHA.115.002092 |
Scopus EID | 2-s2.0-85016925384 |
Open access | Open access |
Page range | 1 - 8 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | |
Additional information | © 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
Place of publication | United Kingdom |
https://acuresearchbank.acu.edu.au/item/8v3y1/acute-heart-failure-and-atrial-fibrillation-insights-from-the-acute-study-of-clinical-effectiveness-of-nesiritide-in-decompensated-heart-failure-ascend-hf-trial
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