Centre for Exercise and Nutrition


TypeDepartment
FacultyFaculty of Health Sciences

Latest research outputs

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Comprehensive assessment of post-prandial protein handling by the application of intrinsically labelled protein in vivo in human subjects
Trommelen, Jorn, Holwerda, Andrew M., Pinckaers, Philippe J. M. and van Loon, Lucas J. C.. (2021). Comprehensive assessment of post-prandial protein handling by the application of intrinsically labelled protein in vivo in human subjects. Proceedings of the Nutrition Society. 80(2), pp. 221-229. https://doi.org/10.1017/S0029665120008034

Journal article

Infographic. UEFA expert group 2020 statement on nutrition in elite football
Collins, James, Maughan, Ronald John, Gleeson, Mike, Bilsborough, Johann, Jeukendrup, Asker, Morton, James P., Phillips, S. M., Armstrong, Lawrence E., Burke, Louise M., Close, Graeme L., Duffield, Rob, Larson-Meyer, Enette, Louis, Julien, Medina, Daniel, Meyer, Flavia, Rollo, Ian, Sundgot-Borgen, Jorunn Kaiander, Wall, Benjamin, Boullosa, Beatriz, ... McCall, Alan. (2021). Infographic. UEFA expert group 2020 statement on nutrition in elite football. British Journal of Sports Medicine. 55(8), pp. 453-455. https://doi.org/10.1136/bjsports-2020-103410

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Energetic demands and nutritional strategies of elite cross-country skiers during Tour de Ski : A narrative review
Heikura, Ida A., Kettunen, Oona, Garthe, Ina, Holmlund, Heidi, Sandbakk, Silvana Bucher, Valtonen, Maarit and Ihalainen, Johanna K.. (2021). Energetic demands and nutritional strategies of elite cross-country skiers during Tour de Ski : A narrative review. Journal of Science in Sport and Exercise. 3(3), pp. 224-237. https://doi.org/10.1007/s42978-020-00105-x

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Dietary protein interventions to improve nutritional status in end-stage renal disease patients undergoing hemodialysis
Hendriks, Floris K., Kooman, Jeroen P. and van Loon, Luc J. C.. (2021). Dietary protein interventions to improve nutritional status in end-stage renal disease patients undergoing hemodialysis. Current Opinion in Clinical Nutrition and Metabolic Care. 24(1), pp. 79-87. https://doi.org/10.1097/MCO.0000000000000703

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A white paper on collagen hydrolyzates and ultrahydrolyzates : Potential supplements to support joint health in osteoarthritis?
Mobasheri, Ali, Mahmoudian, Armaghan, Kalvaityte, Ursule, Uzieliene, Ilona, Larder, Christina E., Iskandar, Michèle M., Kubow, Stan, Hamdan, Paulo Cesar, de Almeida Jr, Cyro Scala, Favazzo, Lacey J., van Loon, Luc J. C., Emans, Pieter J., Plapler, Pérola G. and Zuscik, Michael J.. (2021). A white paper on collagen hydrolyzates and ultrahydrolyzates : Potential supplements to support joint health in osteoarthritis? Current Rheumatology Reports. 23(11), p. Article 78. https://doi.org/10.1007/s11926-021-01042-6

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Nutritional approaches to counter performance constraints in high level sports competition
Burke, Louise M.. (2021). Nutritional approaches to counter performance constraints in high level sports competition. Experimental Physiology. 106(12), pp. 2304-2323. https://doi.org/10.1113/EP088188

Journal article

The anabolic response to plant-based protein ingestion
Pinckaers, Philippe J. M., Trommelen, Jorn, Snijders, Tim and van Loon, Luc J. C.. (2021). The anabolic response to plant-based protein ingestion. Sports Medicine. 51(Supplement 1), pp. 59-74. https://doi.org/10.1007/s40279-021-01540-8

Journal article

Exercise for individuals with bone metastases : A systematic review
Weller, Sarah, Hart, Nicolas H., Bolam, Kate A., Mansfield, Sami, Santa Mina, Daniel, Winters-Stone, Kerri M., Campbell, Anna, Rosenberger, Friedrike, Wiskemann, Joachim, Quist, Morten, Cormie, Prue, Goulart, Jennifer and Campbell, Kristin L.. (2021). Exercise for individuals with bone metastases : A systematic review. Critical Reviews in Oncology Hematology. 166, p. Article 103433. https://doi.org/10.1016/j.critrevonc.2021.103433

Journal article

ACSM expert consensus statement on weight loss in weight-category sports
Burke, Louise M., Slater, Gary J., Matthews, Joseph J., Langan-Evans, Carl and Horswill, Craig A.. (2021). ACSM expert consensus statement on weight loss in weight-category sports. Current Sports Medicine Reports. 20(4), pp. 199-217. https://doi.org/10.1249/JSR.0000000000000831

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Cellular bioenergetics and AMPK and TORC1 signalling in blood lymphoblasts are biomarkers of clinical status in FMR1 premutation carriers
Loesch, Danuta Z., Kemp, Bruce E., Bui, Minh Q., Fisher, Paul R., Allan, Claire Y., Sanislav, Oana, Ngoel, Kevin R. W., Atkinson, Anna, Tassone, Flora, Annesley, Sarah J. and Storey, Elsdon. (2021). Cellular bioenergetics and AMPK and TORC1 signalling in blood lymphoblasts are biomarkers of clinical status in FMR1 premutation carriers. Frontiers in Psychiatry. 12, p. Article 747268. https://doi.org/10.3389/fpsyt.2021.747268

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Effects of exercise on sexual dysfunction in patients with prostate cancer - A systematic review
Reimer, Nadine, Zopf, Eva Maria, Böwe, Rebecca and Baumann, Freerk Theeagnus. (2021). Effects of exercise on sexual dysfunction in patients with prostate cancer - A systematic review. Journal of Sexual Medicine. 18(11), pp. 1899-1914. https://doi.org/10.1016/j.jsxm.2021.09.001

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Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk
Pasmans, Kenneth, Adriaens, Michiel E., Olinga, Peter, Langen, Ramon, Rensen, Sander S., Schaap, Frank G., Damink, Steven W. M. Olde, Caiment, Florian, van Loon, Luc J. C., Blaak, Ellen E. and Meex, Ruth C. R.. (2021). Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk. Frontiers in Endocrinology. 12, p. Article 733625. https://doi.org/10.3389/fendo.2021.733625

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Different frequencies of active interruptions to sitting have distinct effects on 22 h glycemic control in type 2 diabetes
Homer, Ashleigh R., Taylor, Frances C., Dempsey, Paddy C., Wheeler, Michael J., Sethi, Parneet, Grace, Megan S., Green, Daniel J., Cohen, Neale D., Larsen, Robyn N., Kingwell, Bronwyn A., Owen, Neville and Dunstan, David W.. (2021). Different frequencies of active interruptions to sitting have distinct effects on 22 h glycemic control in type 2 diabetes. Nutrition Metabolism and Cardiovascular Diseases. 31(10), pp. 2969-2978. https://doi.org/10.1016/j.numecd.2021.07.001

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Relationships between mitochondrial function, AMPK, and TORC1 signaling in lymphoblasts with premutation alleles of the FMR1 gene
Fisher, Paul R., Allan, Claire Y., Sanislav, Oana, Atkinson, Anna, Ngoei, Kevin R. W., Kemp, Bruce E., Storey, Elsdon, Loesch, Danuta Z. and Annesley, Sarah J.. (2021). Relationships between mitochondrial function, AMPK, and TORC1 signaling in lymphoblasts with premutation alleles of the FMR1 gene. International Journal of Molecular Sciences. 22(19), p. Article 10393. https://doi.org/10.3390/ijms221910393

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Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease
van der Avoort, Cindy M.T., Van Loon, Luc J.C., Verdijk, Lex B., Poyck, Paul P.C., Thijssen, Dick T.J. and Hopman, Maria T.E.. (2021). Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease. International Journal of Sport Nutrition and Exercise Metabolism. 31(5), pp. 385-396. https://doi.org/10.1123/ijsnem.2021-0054

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International Society of Sports Nutrition position stand : Sodium bicarbonate and exercise performance
Grgic, Jozo, Pedisic, Zeljko, Saunders, Bryan, Artioli, Guilherme G., Schoenfeld, Brad J., McKenna, Michael J., Bishop, David J., Kreider, Richard B., Stout, Jeffrey R., Kalman, Douglas S., Arent, Shawn M., VanDusseldorp, Trisha A., Lopez, Hector L., Ziegenfuss, Tim N., Burke, Louise M., Antonio, Jose and Campbell, Bill I.. (2021). International Society of Sports Nutrition position stand : Sodium bicarbonate and exercise performance. Journal of the International Society of Sports Nutrition. 18, p. Article: 61. https://doi.org/10.1186/s12970-021-00458-w

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Mice with whole-body disruption of AMPK-glycogen binding have increased adiposity, reduced fat oxidation and altered tissue glycogen dynamics
Janzen, Natalie, Whitfield, Jamie, Murray-Segal, Lisa, Kemp, Bruce E., Hawley, John A. and Hoffman, Nolan J.. (2021). Mice with whole-body disruption of AMPK-glycogen binding have increased adiposity, reduced fat oxidation and altered tissue glycogen dynamics. International Journal of Molecular Sciences. 22(17), p. Article: 9616. https://doi.org/10.3390/ijms22179616

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Quality of life and symptom burden improve in patients attending a multidisciplinary clinical service for cancer cachexia : A retrospective observational review
Bland, Kelcey A., Harrison, Meg, Harrison, Meg, Zopf, Eva M., Sousa, Mariana S., Currow, David C., Ely, Matthew, Agar, Meera, Butcher, Belinda E., Vaughan, Vanessa, Dowd, Anna and Martin, Peter. (2021). Quality of life and symptom burden improve in patients attending a multidisciplinary clinical service for cancer cachexia : A retrospective observational review. Journal of Pain and Symptom Management. 62(3), pp. e164-e176. https://doi.org/10.1016/j.jpainsymman.2021.02.034

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Higher strength gain after hypoxic vs normoxic resistane training despite no changes in muscle thickness and fractional protein synthetic rate
van Doorslaer de ten Ryen, Sophie, Wanier, Geoffrey, Gnimassou, Olouyomi, Belhaj, Mehdi R., Benoit, Nicolas, Naslain, Damien, Brook, Matthew S., Smith, Kenneth, Wilkinson, Daniel J., Nielens, Henri, Atherton, Philip J., Francaux, Marc and Deldicque, Louise. (2021). Higher strength gain after hypoxic vs normoxic resistane training despite no changes in muscle thickness and fractional protein synthetic rate. The FASEB Journal. 35(8), p. Article: e21773. https://doi.org/10.1096/fj.202100654RR

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Individual physiological and mitochondrial responses during 12 weeks of intensified exercise
Jacques, Macsue, Landen, Shanie, Romero, Javier, Yan, Xu, Garnham, Andrew, Hiam, Danielle, Siegwald, Mélina, Mercier, Emma, Hecksteden, Anne, Eynon, Nir and Voisin, Sarah. (2021). Individual physiological and mitochondrial responses during 12 weeks of intensified exercise. Physiological Reports. 9(15), p. Article: e14962. https://doi.org/10.14814/phy2.14962

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Myofibre hypertrophy in the absence of changes to satellite cell content following concurrent exercise training in young healthy men
Shamim, Baubak, Camera, Donny M. and Whitfield, Jamie. (2021). Myofibre hypertrophy in the absence of changes to satellite cell content following concurrent exercise training in young healthy men. Frontiers in Physiology. 12, p. Article 625044. https://doi.org/10.3389/fphys.2021.625044

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Salsalate reduces atherosclerosis through AMPKβ1 in mice
Day, Emily A., Ford, Rebecca J., Smith, Brennan K., Houde, Vanessa P., Stypa, Stephanie, Rehal, Sonia, Lhotak, Sarka, Kemp, Bruce E., Trigatti, Bernardo L., Werstuck, Geoff H., Austin, Richard C., Fullerton, Morgan D. and Steinberg, Gregory R.. (2021). Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular Metabolism. 53, p. Article: 101321. https://doi.org/10.1016/j.molmet.2021.101321

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Mass spectrometry imaging of L-[ring-13 C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma 
Cao, Jianhua, Balluff, Benjamin, Arts, Martijn, Dubois, Ludwig J., van Loon, Luc J. C., Hackeng, Tilman M., van Eijk, Hans M. H., Eijkel, Gert, Heij, Lara R., Soons, Zita, Olde Damink, Steven W. M. and Heeren, Ron M. A.. (2021). Mass spectrometry imaging of L-[ring-13 C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma . Cancer & Metabolism. 9, p. Article 26. https://doi.org/10.1186/s40170-021-00262-9

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Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial
Hermans, Wesley J. H., Senden, Joan M., Churchward-Venne, Tyler A., Paulussen, Kevin J. M., Fuchs, Cas J., Smeets, Joey S. J., van Loon, Joop J. A., Verdijk, Lex B. and van Loon, Luc J. C.. (2021). Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial. American Journal of Clinical Nutrition. 114(3), pp. 934-944. https://doi.org/10.1093/ajcn/nqab115

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Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in (pre)hypertensive middle-aged and older adults : A 12-wk randomized controlled trial
van der Avoort, Cindy M. T., ten Haaf, Dominique S. M., Bongers, Coen C. W. G., van Oorschot, Frederieke, Verdijk, Lex B., van Loon, Luc J. C. and Hopman, Maria T. E.. (2021). Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in (pre)hypertensive middle-aged and older adults : A 12-wk randomized controlled trial. The Journal of Nutrition. 151(9), pp. 2667-2679. https://doi.org/10.1093/jn/nxab157

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Exercise interventions for people diagnosed with cancer : A systematic review of implementation outcomes
Czosnek, Louise, Richards, Justin, Zopf, Eva, Cormie, Prue, Rosenbaum, Simon and Rankin, Nicole M.. (2021). Exercise interventions for people diagnosed with cancer : A systematic review of implementation outcomes. BMC Cancer. 21, p. Article 643. https://doi.org/10.1186/s12885-021-08196-7

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Neither beetroot juice supplementation nor increased carbohydrate oxidation enhance economy of prolonged exercise in elite race walkers
Burke, Louise M., Hall, Rebecca, Heikura, Ida A., Ross, Megan L., Tee, Nicolin, Kent, Georgina L., Whitfield, Jamie, Forbes, Sara F., Sharma, Avish P., Jones, Andrew M., Peeling, Peter, Blackwell, Jamie R., Mujika, Iñigo, Mackay, Karen, Kozior, Marta, Vallance, Brent and McKay, Alannah K. A.. (2021). Neither beetroot juice supplementation nor increased carbohydrate oxidation enhance economy of prolonged exercise in elite race walkers. Nutrients. 13(8), p. Article 2767. https://doi.org/10.3390/nu13082767

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Patients and carers' perspectives of participating in a pilot tailored exercise program during chemoradiotherapy for high grade glioma : A qualitative study
Halkett, Georgia K. B., Cormie, Prue, McGough, Shirley, Zopf, Eva M., Galvao, Daniel A., Newton, Robert U. and Nowak, Anna K.. (2021). Patients and carers' perspectives of participating in a pilot tailored exercise program during chemoradiotherapy for high grade glioma : A qualitative study. European Journal of Cancer Care. 30(5), p. Article: e13453. https://doi.org/10.1111/ecc.13453

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The validity of ultrasound technology in providing an indirect estimate of muscle glycogen concentrations is equivocal
Bone, Julia L., Ross, Megan L., Tomcik, Kristyen A., Jeacocke, Nikki A., McKay, Alannah K. A. and Burke, Louise M.. (2021). The validity of ultrasound technology in providing an indirect estimate of muscle glycogen concentrations is equivocal. Nutrients. 13(7), p. Article 2371. https://doi.org/10.3390/nu13072371

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Eat like an athlete : Insights of sports nutrition science to support active aging in healthy older adults
Oikawa, Sara Y., Brisbois, Tristin D., van Loon, Luc J. C. and Rollo, Ian. (2021). Eat like an athlete : Insights of sports nutrition science to support active aging in healthy older adults. GeroScience. 43(5), pp. 2485-2495. https://doi.org/10.1007/s11357-021-00419-w

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Undeclared doping substances are highly prevalent in commercial sports nutrition supplements
Duiven, Erik, Luc J.C. van Loon, Spruijt, Laila, Koert, Willem and de Hon, Olivier M.. (2021). Undeclared doping substances are highly prevalent in commercial sports nutrition supplements. Journal of Sports Science and Medicine. 20, pp. 328-338. https://doi.org/10.52082/jssm.2021.328

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Skeletal muscle adaptive responses to different types of short-term exercise training and detraining in middle-age men
Callahan, Marcus J., Parr, Evelyn B., Snijders, Tim, Conceição, Miguel S., Radford, Bridget E., Timmins, Ryan G., Devlin, Brooke L., Hawley, John A. and Camera, Donny M.. (2021). Skeletal muscle adaptive responses to different types of short-term exercise training and detraining in middle-age men. Medicine and Science in Sports and Exercise. 53(10), pp. 2023-2036. https://doi.org/10.1249/MSS.0000000000002684

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No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males
Pinckaers, Philippe J. M., Kouw, Imre W. K., Hendriks, Floris K., van Kranenburg, Janneau M. X., de Groot, Lisette C. P. G. M., Verdijk, Lex B., Snijders, Tim and van Loon, Luc J. C.. (2021). No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males. British Journal of Nutrition. 126(12), pp. 1832-1842. https://doi.org/10.1017/S0007114521000635

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Frequency of interruptions to sitting time : Benefits for postprandial metabolism in type 2 diabetes
Homer, Ashleigh R., Taylor, Frances C., Dempsey, Paddy C., Wheeler, Michael J., Sethi, Parneet, Townsend, Melanie K., Grace, Megan S., Green, Daniel J., Cohen, Neale D., Larsen, Robyn N., Kingwell, Bronwyn A., Owen, Neville and Dunstan, David W.. (2021). Frequency of interruptions to sitting time : Benefits for postprandial metabolism in type 2 diabetes. Diabetes Care. 44(6), pp. 1-10. https://doi.org/10.2337/dc20-1410

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Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial
Murphy, Caoileann H., Flanagan, Ellen M., De Vito, Giuseppe, Susta, Davide, Mitchelson, Kathleen A. J., de Marco Castro, Elena, Senden, Joan M. G., Goessens, Joy P. B., Mikłosz, Agnieszka, Chabowski, Adrian, Segurado, Ricardo, Corish, Clare A., McCarthy, Sinead N., Egan, Brendan, van Loon, Luc J. C. and Roche, Helen M.. (2021). Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial. American Journal of Clinical Nutrition. 113(6), pp. 1411-1427. https://doi.org/10.1093/ajcn/nqaa449

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Development of a "cooling" menthol energy gel for endurance athletes : Effect of menthol concentration on acceptability and preferences
Stevens, Christopher J., Ross, Megan L. R. and Vogel, Roxanne M.. (2021). Development of a "cooling" menthol energy gel for endurance athletes : Effect of menthol concentration on acceptability and preferences. International Journal of Sport Nutrition and Exercise Metabolism. 31(1), pp. 40-45. https://doi.org/10.1123/IJSNEM.2020-0190

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Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men
Shad, Brandon J., Thompson, Janice L., McKendry, James, Holwerda, Andrew M., Elhassan, Yasir S., Breen, Leigh, van Loon, Luc J. C. and Wallis, Gareth A.. (2021). Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men. International Journal of Sport Nutrition and Exercise Metabolism. 31(3), pp. 209-216. https://doi.org/10.1123/IJSNEM.2020-0274

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Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle
Smeets, Joey S. J., Horstman, Astrid M. H., van Dijk, David P. J., van Boxtel, Astrid G. M., ter Woorst, Joost F., Damink, Steven W. M. Olde, Schijns, Olaf E. M. G. and van Loon, Luc J. C.. (2021). Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle. Journal of Cachexia, Sarcopenia and Muscle. 12(3), pp. 769-778. https://doi.org/10.1002/jcsm.12701

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Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults
Snijders, Tim, Holwerda, Andy M., van Loon, Luc J. C. and Verdijk, Lex B.. (2021). Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults. Acta Physiologica. 231(4), p. e13599. https://doi.org/10.1111/apha.13599

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Ketogenic low-CHO, high-fat diet : The future of elite endurance sport?
Burke, Louise. (2021). Ketogenic low-CHO, high-fat diet : The future of elite endurance sport? The Journal of Physiology. 599(3), pp. 819-843. https://doi.org/10.1113/JP278928

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