Centre for Exercise and Nutrition


TypeDepartment
FacultyFaculty of Health Sciences

Latest research outputs

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ACSM expert consensus statement on weight loss in weight-category sports
Burke, Louise M., Slater, Gary J., Matthews, Joseph J., Langan-Evans, Carl and Horswill, Craig A.. (2021). ACSM expert consensus statement on weight loss in weight-category sports. Current Sports Medicine Reports. 20(4), pp. 199-217. https://doi.org/10.1249/JSR.0000000000000831

Journal article

Cellular bioenergetics and AMPK and TORC1 signalling in blood lymphoblasts are biomarkers of clinical status in FMR1 premutation carriers
Loesch, Danuta Z., Kemp, Bruce E., Bui, Minh Q., Fisher, Paul R., Allan, Claire Y., Sanislav, Oana, Ngoel, Kevin R. W., Atkinson, Anna, Tassone, Flora, Annesley, Sarah J. and Storey, Elsdon. (2021). Cellular bioenergetics and AMPK and TORC1 signalling in blood lymphoblasts are biomarkers of clinical status in FMR1 premutation carriers. Frontiers in Psychiatry. 12, p. Article 747268. https://doi.org/10.3389/fpsyt.2021.747268

Journal article

Effects of exercise on sexual dysfunction in patients with prostate cancer - A systematic review
Reimer, Nadine, Zopf, Eva Maria, Böwe, Rebecca and Baumann, Freerk Theeagnus. (2021). Effects of exercise on sexual dysfunction in patients with prostate cancer - A systematic review. Journal of Sexual Medicine. 18(11), pp. 1899-1914. https://doi.org/10.1016/j.jsxm.2021.09.001

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Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk
Pasmans, Kenneth, Adriaens, Michiel E., Olinga, Peter, Langen, Ramon, Rensen, Sander S., Schaap, Frank G., Damink, Steven W. M. Olde, Caiment, Florian, van Loon, Luc J. C., Blaak, Ellen E. and Meex, Ruth C. R.. (2021). Hepatic steatosis contributes to the development of muscle atrophy via inter-organ crosstalk. Frontiers in Endocrinology. 12, p. Article 733625. https://doi.org/10.3389/fendo.2021.733625

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Different frequencies of active interruptions to sitting have distinct effects on 22 h glycemic control in type 2 diabetes
Homer, Ashleigh R., Taylor, Frances C., Dempsey, Paddy C., Wheeler, Michael J., Sethi, Parneet, Grace, Megan S., Green, Daniel J., Cohen, Neale D., Larsen, Robyn N., Kingwell, Bronwyn A., Owen, Neville and Dunstan, David W.. (2021). Different frequencies of active interruptions to sitting have distinct effects on 22 h glycemic control in type 2 diabetes. Nutrition Metabolism and Cardiovascular Diseases. 31(10), pp. 2969-2978. https://doi.org/10.1016/j.numecd.2021.07.001

Journal article

Relationships between mitochondrial function, AMPK, and TORC1 signaling in lymphoblasts with premutation alleles of the FMR1 gene
Fisher, Paul R., Allan, Claire Y., Sanislav, Oana, Atkinson, Anna, Ngoei, Kevin R. W., Kemp, Bruce E., Storey, Elsdon, Loesch, Danuta Z. and Annesley, Sarah J.. (2021). Relationships between mitochondrial function, AMPK, and TORC1 signaling in lymphoblasts with premutation alleles of the FMR1 gene. International Journal of Molecular Sciences. 22(19), p. Article 10393. https://doi.org/10.3390/ijms221910393

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Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease
van der Avoort, Cindy M.T., Van Loon, Luc J.C., Verdijk, Lex B., Poyck, Paul P.C., Thijssen, Dick T.J. and Hopman, Maria T.E.. (2021). Acute effects of dietary nitrate on exercise tolerance, muscle oxygenation, and cardiovascular function in patients with peripheral arterial disease. International Journal of Sport Nutrition and Exercise Metabolism. 31(5), pp. 385-396. https://doi.org/10.1123/ijsnem.2021-0054

Journal article

International Society of Sports Nutrition position stand : Sodium bicarbonate and exercise performance
Grgic, Jozo, Pedisic, Zeljko, Saunders, Bryan, Artioli, Guilherme G., Schoenfeld, Brad J., McKenna, Michael J., Bishop, David J., Kreider, Richard B., Stout, Jeffrey R., Kalman, Douglas S., Arent, Shawn M., VanDusseldorp, Trisha A., Lopez, Hector L., Ziegenfuss, Tim N., Burke, Louise M., Antonio, Jose and Campbell, Bill I.. (2021). International Society of Sports Nutrition position stand : Sodium bicarbonate and exercise performance. Journal of the International Society of Sports Nutrition. 18, p. Article: 61. https://doi.org/10.1186/s12970-021-00458-w

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Mice with whole-body disruption of AMPK-glycogen binding have increased adiposity, reduced fat oxidation and altered tissue glycogen dynamics
Janzen, Natalie, Whitfield, Jamie, Murray-Segal, Lisa, Kemp, Bruce E., Hawley, John A. and Hoffman, Nolan J.. (2021). Mice with whole-body disruption of AMPK-glycogen binding have increased adiposity, reduced fat oxidation and altered tissue glycogen dynamics. International Journal of Molecular Sciences. 22(17), p. Article: 9616. https://doi.org/10.3390/ijms22179616

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Quality of life and symptom burden improve in patients attending a multidisciplinary clinical service for cancer cachexia : A retrospective observational review
Bland, Kelcey A., Harrison, Meg, Harrison, Meg, Zopf, Eva M., Sousa, Mariana S., Currow, David C., Ely, Matthew, Agar, Meera, Butcher, Belinda E., Vaughan, Vanessa, Dowd, Anna and Martin, Peter. (2021). Quality of life and symptom burden improve in patients attending a multidisciplinary clinical service for cancer cachexia : A retrospective observational review. Journal of Pain and Symptom Management. 62(3), pp. e164-e176. https://doi.org/10.1016/j.jpainsymman.2021.02.034

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Higher strength gain after hypoxic vs normoxic resistane training despite no changes in muscle thickness and fractional protein synthetic rate
van Doorslaer de ten Ryen, Sophie, Wanier, Geoffrey, Gnimassou, Olouyomi, Belhaj, Mehdi R., Benoit, Nicolas, Naslain, Damien, Brook, Matthew S., Smith, Kenneth, Wilkinson, Daniel J., Nielens, Henri, Atherton, Philip J., Francaux, Marc and Deldicque, Louise. (2021). Higher strength gain after hypoxic vs normoxic resistane training despite no changes in muscle thickness and fractional protein synthetic rate. The FASEB Journal. 35(8), p. Article: e21773. https://doi.org/10.1096/fj.202100654RR

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Individual physiological and mitochondrial responses during 12 weeks of intensified exercise
Jacques, Macsue, Landen, Shanie, Romero, Javier, Yan, Xu, Garnham, Andrew, Hiam, Danielle, Siegwald, Mélina, Mercier, Emma, Hecksteden, Anne, Eynon, Nir and Voisin, Sarah. (2021). Individual physiological and mitochondrial responses during 12 weeks of intensified exercise. Physiological Reports. 9(15), p. Article: e14962. https://doi.org/10.14814/phy2.14962

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Myofibre hypertrophy in the absence of changes to satellite cell content following concurrent exercise training in young healthy men
Shamim, Baubak, Camera, Donny M. and Whitfield, Jamie. (2021). Myofibre hypertrophy in the absence of changes to satellite cell content following concurrent exercise training in young healthy men. Frontiers in Physiology. 12, p. Article 625044. https://doi.org/10.3389/fphys.2021.625044

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Salsalate reduces atherosclerosis through AMPKβ1 in mice
Day, Emily A., Ford, Rebecca J., Smith, Brennan K., Houde, Vanessa P., Stypa, Stephanie, Rehal, Sonia, Lhotak, Sarka, Kemp, Bruce E., Trigatti, Bernardo L., Werstuck, Geoff H., Austin, Richard C., Fullerton, Morgan D. and Steinberg, Gregory R.. (2021). Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular Metabolism. 53, p. Article: 101321. https://doi.org/10.1016/j.molmet.2021.101321

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Mass spectrometry imaging of L-[ring-13 C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma 
Cao, Jianhua, Balluff, Benjamin, Arts, Martijn, Dubois, Ludwig J., van Loon, Luc J. C., Hackeng, Tilman M., van Eijk, Hans M. H., Eijkel, Gert, Heij, Lara R., Soons, Zita, Olde Damink, Steven W. M. and Heeren, Ron M. A.. (2021). Mass spectrometry imaging of L-[ring-13 C6]- labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma . Cancer & Metabolism. 9, p. Article 26. https://doi.org/10.1186/s40170-021-00262-9

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Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial
Hermans, Wesley J. H., Senden, Joan M., Churchward-Venne, Tyler A., Paulussen, Kevin J. M., Fuchs, Cas J., Smeets, Joey S. J., van Loon, Joop J. A., Verdijk, Lex B. and van Loon, Luc J. C.. (2021). Insects are a viable protein source for human consumption : From insect protein digestion to postprandial muscle protein synthesis in vivo in humans : A double-blind randomized trial. American Journal of Clinical Nutrition. 114(3), pp. 934-944. https://doi.org/10.1093/ajcn/nqab115

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Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in (pre)hypertensive middle-aged and older adults : A 12-wk randomized controlled trial
van der Avoort, Cindy M. T., ten Haaf, Dominique S. M., Bongers, Coen C. W. G., van Oorschot, Frederieke, Verdijk, Lex B., van Loon, Luc J. C. and Hopman, Maria T. E.. (2021). Increasing nitrate-rich vegetable intake lowers ambulatory blood pressure in (pre)hypertensive middle-aged and older adults : A 12-wk randomized controlled trial. The Journal of Nutrition. 151(9), pp. 2667-2679. https://doi.org/10.1093/jn/nxab157

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Exercise interventions for people diagnosed with cancer : A systematic review of implementation outcomes
Czosnek, Louise, Richards, Justin, Zopf, Eva, Cormie, Prue, Rosenbaum, Simon and Rankin, Nicole M.. (2021). Exercise interventions for people diagnosed with cancer : A systematic review of implementation outcomes. BMC Cancer. 21, p. Article 643. https://doi.org/10.1186/s12885-021-08196-7

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Neither beetroot juice supplementation nor increased carbohydrate oxidation enhance economy of prolonged exercise in elite race walkers
Burke, Louise M., Hall, Rebecca, Heikura, Ida A., Ross, Megan L., Tee, Nicolin, Kent, Georgina L., Whitfield, Jamie, Forbes, Sara F., Sharma, Avish P., Jones, Andrew M., Peeling, Peter, Blackwell, Jamie R., Mujika, Iñigo, Mackay, Karen, Kozior, Marta, Vallance, Brent and McKay, Alannah K. A.. (2021). Neither beetroot juice supplementation nor increased carbohydrate oxidation enhance economy of prolonged exercise in elite race walkers. Nutrients. 13(8), p. Article 2767. https://doi.org/10.3390/nu13082767

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Patients and carers' perspectives of participating in a pilot tailored exercise program during chemoradiotherapy for high grade glioma : A qualitative study
Halkett, Georgia K. B., Cormie, Prue, McGough, Shirley, Zopf, Eva M., Galvao, Daniel A., Newton, Robert U. and Nowak, Anna K.. (2021). Patients and carers' perspectives of participating in a pilot tailored exercise program during chemoradiotherapy for high grade glioma : A qualitative study. European Journal of Cancer Care. 30(5), p. Article: e13453. https://doi.org/10.1111/ecc.13453

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The validity of ultrasound technology in providing an indirect estimate of muscle glycogen concentrations is equivocal
Bone, Julia L., Ross, Megan L., Tomcik, Kristyen A., Jeacocke, Nikki A., McKay, Alannah K. A. and Burke, Louise M.. (2021). The validity of ultrasound technology in providing an indirect estimate of muscle glycogen concentrations is equivocal. Nutrients. 13(7), p. Article 2371. https://doi.org/10.3390/nu13072371

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Eat like an athlete : Insights of sports nutrition science to support active aging in healthy older adults
Oikawa, Sara Y., Brisbois, Tristin D., van Loon, Luc J. C. and Rollo, Ian. (2021). Eat like an athlete : Insights of sports nutrition science to support active aging in healthy older adults. GeroScience. 43(5), pp. 2485-2495. https://doi.org/10.1007/s11357-021-00419-w

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Undeclared doping substances are highly prevalent in commercial sports nutrition supplements
Duiven, Erik, Luc J.C. van Loon, Spruijt, Laila, Koert, Willem and de Hon, Olivier M.. (2021). Undeclared doping substances are highly prevalent in commercial sports nutrition supplements. Journal of Sports Science and Medicine. 20, pp. 328-338. https://doi.org/10.52082/jssm.2021.328

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Skeletal muscle adaptive responses to different types of short-term exercise training and detraining in middle-age men
Callahan, Marcus J., Parr, Evelyn B., Snijders, Tim, Conceição, Miguel S., Radford, Bridget E., Timmins, Ryan G., Devlin, Brooke L., Hawley, John A. and Camera, Donny M.. (2021). Skeletal muscle adaptive responses to different types of short-term exercise training and detraining in middle-age men. Medicine and Science in Sports and Exercise. 53(10), pp. 2023-2036. https://doi.org/10.1249/MSS.0000000000002684

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No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males
Pinckaers, Philippe J. M., Kouw, Imre W. K., Hendriks, Floris K., van Kranenburg, Janneau M. X., de Groot, Lisette C. P. G. M., Verdijk, Lex B., Snijders, Tim and van Loon, Luc J. C.. (2021). No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males. British Journal of Nutrition. 126(12), pp. 1832-1842. https://doi.org/10.1017/S0007114521000635

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Frequency of interruptions to sitting time : Benefits for postprandial metabolism in type 2 diabetes
Homer, Ashleigh R., Taylor, Frances C., Dempsey, Paddy C., Wheeler, Michael J., Sethi, Parneet, Townsend, Melanie K., Grace, Megan S., Green, Daniel J., Cohen, Neale D., Larsen, Robyn N., Kingwell, Bronwyn A., Owen, Neville and Dunstan, David W.. (2021). Frequency of interruptions to sitting time : Benefits for postprandial metabolism in type 2 diabetes. Diabetes Care. 44(6), pp. 1-10. https://doi.org/10.2337/dc20-1410

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Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial
Murphy, Caoileann H., Flanagan, Ellen M., De Vito, Giuseppe, Susta, Davide, Mitchelson, Kathleen A. J., de Marco Castro, Elena, Senden, Joan M. G., Goessens, Joy P. B., Mikłosz, Agnieszka, Chabowski, Adrian, Segurado, Ricardo, Corish, Clare A., McCarthy, Sinead N., Egan, Brendan, van Loon, Luc J. C. and Roche, Helen M.. (2021). Does supplementation with leucine-enriched protein alone and in combination with fish-oil-derived n-3 PUFA affect muscle mass, strength, physical performance, and muscle protein synthesis in well-nourished older adults? A randomized, double-blind, placebo-controlled trial. American Journal of Clinical Nutrition. 113(6), pp. 1411-1427. https://doi.org/10.1093/ajcn/nqaa449

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Development of a "cooling" menthol energy gel for endurance athletes : Effect of menthol concentration on acceptability and preferences
Stevens, Christopher J., Ross, Megan L. R. and Vogel, Roxanne M.. (2021). Development of a "cooling" menthol energy gel for endurance athletes : Effect of menthol concentration on acceptability and preferences. International Journal of Sport Nutrition and Exercise Metabolism. 31(1), pp. 40-45. https://doi.org/10.1123/IJSNEM.2020-0190

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Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men
Shad, Brandon J., Thompson, Janice L., McKendry, James, Holwerda, Andrew M., Elhassan, Yasir S., Breen, Leigh, van Loon, Luc J. C. and Wallis, Gareth A.. (2021). Daily myofibrillar protein synthesis rates in response to low- And high-frequency resistance exercise training in healthy, young men. International Journal of Sport Nutrition and Exercise Metabolism. 31(3), pp. 209-216. https://doi.org/10.1123/IJSNEM.2020-0274

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Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle
Smeets, Joey S. J., Horstman, Astrid M. H., van Dijk, David P. J., van Boxtel, Astrid G. M., ter Woorst, Joost F., Damink, Steven W. M. Olde, Schijns, Olaf E. M. G. and van Loon, Luc J. C.. (2021). Basal protein synthesis rates differ between vastus lateralis and rectus abdominis muscle. Journal of Cachexia, Sarcopenia and Muscle. 12(3), pp. 769-778. https://doi.org/10.1002/jcsm.12701

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Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults
Snijders, Tim, Holwerda, Andy M., van Loon, Luc J. C. and Verdijk, Lex B.. (2021). Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults. Acta Physiologica. 231(4), p. e13599. https://doi.org/10.1111/apha.13599

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Ketogenic low-CHO, high-fat diet : The future of elite endurance sport?
Burke, Louise. (2021). Ketogenic low-CHO, high-fat diet : The future of elite endurance sport? The Journal of Physiology. 599(3), pp. 819-843. https://doi.org/10.1113/JP278928

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Athlete health and safety at large sport events : The development of consensus-driven guidelines
Mountjoy, Margo, Moran, Jane, Ahmed, Hosny, Bermon, Stephane, Bigard, Xavier, Doerr, Dominik, Lacoste, Alain, Miller, Stuart, Weber, Alexis, Foster, Jeremy, Budgett, Richard, Engebretsen, Lars, Burke, Louise M., Gouttebarge, Vincent, McCloskey, Brian, Piccininni, Paul, Racinais, Sebastien, Stuart, Mark and Zideman, David. (2021). Athlete health and safety at large sport events : The development of consensus-driven guidelines. British Journal of Sports Medicine. 55(4), pp. 191-197. https://doi.org/10.1136/bjsports-2020-102771

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The impact of beetroot juice supplementation on muscular endurance, maximal strength and countermovement jump performance
Jonvik, Kristin L., Hoogervorst, Daan, Peelen, Harmen B., de Niet, Mark, Verdijk, Lex B., van Loon, Luc J. C. and van Dijk, Jan-Willem. (2021). The impact of beetroot juice supplementation on muscular endurance, maximal strength and countermovement jump performance. European Journal of Sport Science. 21(6), pp. 871-878. https://doi.org/10.1080/17461391.2020.1788649

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Assessing the whole-body protein synthetic response to feeding in vivo in human subjects
Trommelen, Jorn and Van Loon, Luc J. C.. (2021). Assessing the whole-body protein synthetic response to feeding in vivo in human subjects. Proceedings of the Nutrition Society. 80, pp. 139-147. https://doi.org/10.1017/S0029665120008009

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Traditional markers of cardiac toxicity fail to detect marked reductions in cardiorespiratory fitness among cancer patients undergoing anti-cancer treatment
Howden, Erin J., Foulkes, Steve, Dillon, Hayley T., Bigaran, Ashley, Wright, Leah, Janssens, Kristel, Comie, Prue, Costello, Benedict and La Gerche, André. (2021). Traditional markers of cardiac toxicity fail to detect marked reductions in cardiorespiratory fitness among cancer patients undergoing anti-cancer treatment. European Heart Journal: Cardiovascular Imaging. 22(4), pp. 451-458. https://doi.org/10.1093/ehjci/jeaa421

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Postexercise hot-water immersion does not further enhance heat adaptation or performance in endurance athletes training in a hot environment
Stevens, Christopher J., Ross, Megan L. R., Carr, Amelia J., Vallance, Brent, Best, Russ, Urwin, Charles, Periard, Julien D. and Burke, Louise. (2021). Postexercise hot-water immersion does not further enhance heat adaptation or performance in endurance athletes training in a hot environment. International Journal of Sports Physiology and Performance. 16(4), pp. 480-488. https://doi.org/10.1123/ijspp.2020-0114

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The effect of exercise training on cardiometabolic health in men with prostate cancer receiving androgen deprivation therapy : A systematic review and meta-analysis
Bigaran, Ashley, Zopf, Eva, Gardner, Jason, La Gerche, Andre, Murphy, Declan G., Howden, Erin J., Baker, Michael K. and Cormie, Prue. (2021). The effect of exercise training on cardiometabolic health in men with prostate cancer receiving androgen deprivation therapy : A systematic review and meta-analysis. Prostate Cancer and Prostatic Diseases. 24(1), pp. 35-48. https://doi.org/10.1038/s41391-020-00273-5

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Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men
Holwerda, Andrew M., Trommelen, Jorn, Kouw, Imre W. K., Senden, Joan M., Goessens, Joy P. B., van Kranenburg, Janneau, Gijsen, Annemie P., Verdijk, Lex B. and van Loon, Luc J. C.. (2021). Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men. International Journal of Sport Nutrition and Exercise Metabolism. 31(3), pp. 317-226. https://doi.org/10.1123/ijsnem.2020-0222

Journal article

Lower nocturnal blood glucose response to a potato-based mixed evening meal compared to rice in individuals with type 2 diabetes
Devlin, Brooke L., Parr, Evelyn B., Radford, Bridget E. and Hawley, John A.. (2021). Lower nocturnal blood glucose response to a potato-based mixed evening meal compared to rice in individuals with type 2 diabetes. Clinical Nutrition. 40(4), pp. 2200-2209. https://doi.org/10.1016/j.clnu.2020.09.049

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