Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial

Journal article


Volterman, Kimberly A., Moore, Daniel R., Breithaupt, Peter, Grathwohl, Dominik, Offord, Elizabeth A., Karagounis, Leonidas G. and Timmons, Brian W.. (2017). Timing and pattern of postexercise protein ingestion affects whole-body protein balance in healthy children : A randomized trial. Applied Physiology, Nutrition and Metabolism. 42(11), pp. 1142-1148. https://doi.org/10.1139/apnm-2017-0185
AuthorsVolterman, Kimberly A., Moore, Daniel R., Breithaupt, Peter, Grathwohl, Dominik, Offord, Elizabeth A., Karagounis, Leonidas G. and Timmons, Brian W.
Abstract

The dose and timing of postexercise protein ingestion can influence whole-body protein balance (WBPB) in adults, although comparable data from children are scarce. This study investigated how protein intake (both amount and distribution) postexercise can affect WBPB in physically active children. Thirty-five children (26 males; 9–13 years old) underwent a 5-day adaptation diet, maintaining a protein intake of 0.95 g·kg−1·day−1. Participants consumed [15N]glycine (2 mg·kg−1) before performing 3 × 20 min of variable-intensity cycling, and whole-body protein kinetics were assessed over 6 and 24 h of recovery. Fifteen grams of protein was distributed across 2 isoenergetic carbohydrate-containing beverages (15 and 240 min postexercise) containing reciprocal amounts of protein (i.e., 0 + 15 g, 5 + 10 g, 10 + 5 g, and 15 + 0 g for Groups A–D, respectively). Over the 6 h that included the exercise bout and consumption of the first beverage at 15 min postexercise, WBPB (i.e., synthesis – breakdown) demonstrated a linear increase of 0.647 g·kg−1·day−1 per 1 g protein intake (P < 0.001). Over 24 h, robust regression revealed that WBPB was best modeled by a parabola (P < 0.05), suggesting that a maximum in WBPB was achieved between groups B and C. In conclusion, despite a dose response early in recovery, a periodized protein intake with multiple smaller doses after physical activity may be more beneficial than a single bolus dose in promoting daily WBPB in healthy active children.

Keywordsprotein metabolism; protein distribution; physical activity; adolescents; youth; growth; muscle; lean body mass
Year2017
JournalApplied Physiology, Nutrition and Metabolism
Journal citation42 (11), pp. 1142-1148
PublisherCanadian Science Publishing
ISSN1715-5312
Digital Object Identifier (DOI)https://doi.org/10.1139/apnm-2017-0185
PubMed ID28683243
Scopus EID2-s2.0-85032509032
Open accessPublished as green open access
Page range1142-1148
FunderNESTEC
Author's accepted manuscript
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All rights reserved
File Access Level
Open
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online06 Jul 2017
Publication process dates
Accepted26 Jun 2017
Deposited21 Nov 2023
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