Enhanced cannabis timeline followback (EC-TLFB) : Comprehensive assessment of cannabis use including standard THC units and validation through biological measures

Journal article

Petrilli, Kat, Lawn, Will, Lees, Rachel, Mokrysz, Claire, Borissova, Anya, Ofori, Shelan, Trinci, Katie, dos Santos, Renato, Leitch, Harry, Soni, Shilpa, Hines, Lindsey A., Lorenzetti, Valentina, Curran, H. Valerie and Freeman, Tom P.. (2024). Enhanced cannabis timeline followback (EC-TLFB) : Comprehensive assessment of cannabis use including standard THC units and validation through biological measures. Addiction. 119(4), pp. 772-783. https://doi.org/10.1111/add.16405
AuthorsPetrilli, Kat, Lawn, Will, Lees, Rachel, Mokrysz, Claire, Borissova, Anya, Ofori, Shelan, Trinci, Katie, dos Santos, Renato, Leitch, Harry, Soni, Shilpa, Hines, Lindsey A., Lorenzetti, Valentina, Curran, H. Valerie and Freeman, Tom P.
Abstract

Aims
The aims of this study were to present an enhanced cannabis timeline followback (EC-TLFB) enabling comprehensive assessment of cannabis use measures, including standard tetrahydrocannabinol (THC) units, and to validate these against objectively indexed urinary 11-nor-9-carboxy-tetrahydrocannabinol (THC-COOH) concentrations.

Design
We used cross-sectional baseline data from the ‘CannTeen’ observational longitudinal study.

Setting
The study was conducted in London, UK.

Participants
A total of 147 participants who used cannabis regularly took part in the study (n = 71 female, n = 76 male; mean age = 21.90, standard deviation = 5.32).

Measurements
The EC-TLFB was used to calculate frequency of cannabis use, method of administration, including co-administration with tobacco, amount of cannabis used (measured with unaided self-report and also using pictorial aided self-report) and type of cannabis product (flower, hash) which was used to estimate THC concentration (both from published data on THC concentration of products and analysis of cannabis samples donated by participants in this study). We calculated total weekly standard THC units (i.e. 5 mg THC for all cannabis products and methods of administration) using the EC-TLFB. The outcome variable for validation of past week EC-TLFB assessments was creatinine-normalized carboxy-tetrahydrocannabinol (THC-COOH) in urine.

Findings
All measures of cannabis exposure included in this analysis were positively correlated with levels of THC-COOH in urine (r = 0.41–0.52). Standard THC units, calculated with average concentrations of THC in cannabis in the UK and unaided self-report measures of amount of cannabis used in grams showed the strongest correlation with THC-COOH in urine (r = 0.52, 95% bias-corrected and accelerated = 0.26–0.70).

Conclusions
The enhanced cannabis timeline followback (EC-TLFB) can provide a valid assessment of a comprehensive set of cannabis use measures including standard tetrahydrocannabinol units as well as and traditional TLFB assessments (e.g. frequency of use and grams of cannabis use).

Keywordsassessment; cannabis; dose; EC-TLFB; measurement; standardization
Year2024
JournalAddiction
Journal citation119 (4), pp. 772-783
PublisherJohn Wiley & Sons Ltd
ISSN0965-2140
Digital Object Identifier (DOI)https://doi.org/10.1111/add.16405
PubMed ID38105033
Scopus EID2-s2.0-85179981245
Open accessPublished as ‘gold’ (paid) open access
Page range772-783
FunderMedical Research Council (MRC), United Kingdom
Economic and Social Research Council (ESRC)
South West Doctoral Training Partnership (SWDTP)
Wellcome Trust
Publisher's version
License
File Access Level
Open
Output statusPublished
Publication dates
Online17 Dec 2023
Publication process dates
Accepted06 Nov 2023
Deposited22 Apr 2025
Grant IDMR/P012728/1
209158/Z/17/Z
Additional information

© 2023 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Acute effects of MDMA on trust, cooperative behaviour and empathy : A double-blind, placebo-controlled experiment
Borissova, Anna, Ferguson, Bart, Wall, Matthew B., Morgan, Celia J. A., Carhart-Harris, R. L., Bolstridge, M., Bloomfield, Michael A. P., Williams, Tim M., Feilding, Amanda, Murphy, Kevin, Tyacke, Robin J., Erritzoe, David, Stewart, Lorna, Wolff, Kim, Nutt, David, Curran, H. Valerie and Lawn, Will. (2021). Acute effects of MDMA on trust, cooperative behaviour and empathy : A double-blind, placebo-controlled experiment. Journal of Psychopharmacology. 35(5), pp. 547-555. https://doi.org/10.1177/0269881120926673
Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults?
Daedelow, Laura S., Banaschewski, Tobias, Berning, Moritz, Bokde, Arun L. W., Brühl, Rüdiger, Burke Quinlan, Erin, Curran, H. Valerie, Desrivieres, Sylvane, Flor, Herta, Grigis, Antoine, Garavan, Hugh, Hardon, Anita, Kaminski, Jakob, Martinot, Jean-Luc, Paillère Martinot, Marie-Laure, Artiges, Eric, Murray, Hayley, Nees, Frauke, Oei, Nicole Y. L., ... IMAGEN Consortium. (2021). Are psychotic-like experiences related to a discontinuation of cannabis consumption in young adults? Schizophrenia Research. 228, pp. 271-279. https://doi.org/10.1016/j.schres.2021.01.002
Standard units for cannabis dose : Why is it important to standardize cannabis dose for drug policy and how can we enhance its place on the public health agenda?
López-Pelayo, Hugo, Matrai, Silvia, Balcells-Olivero, Mercè, Campeny, Eugènia, Braddick, Fleur, Bossong, Matthijs G., Cruz, Olga S., Deluca, Paolo, Dom, Geert, Feingold, Daniel, Freeman, Tom P., Guzman, Pablo, Hindocha, Chandni, Kelly, Brian C., Liebregts, Nienke, Lorenzetti, Valentina, Manthey, Jakob, Matias, João, Oliveras, Clara, ... Gual, Antoni. (2021). Standard units for cannabis dose : Why is it important to standardize cannabis dose for drug policy and how can we enhance its place on the public health agenda? International Journal of Drug Policy. 97, p. Article 103350. https://doi.org/10.1016/j.drugpo.2021.103350
A standard THC unit for reporting of health research on cannabis and cannabinoids
Freeman, Tom P. and Lorenzetti, Valentina. (2021). A standard THC unit for reporting of health research on cannabis and cannabinoids. The Lancet Psychiatry. 8(11), pp. 944-946. https://doi.org/10.1016/S2215-0366(21)00355-2
Brain imaging and substance use disorders : Focus on white matter microstructural integrity
Rossetti, Maria Gloria, Crisanti, Camilla, Brambilla, Paolo and Lorenzetti, Valentina. (2021). Brain imaging and substance use disorders : Focus on white matter microstructural integrity. In In Della Sala, Sergio (Ed.). Encyclopedia of behavioral neuroscience ; volume 1 pp. 652-673 Elsevier Science. https://doi.org/10.1016/B978-0-12-819641-0.00117-1
Prospective memory deficits following acute alcohol consumption
Elliott, Morgan, Terrett, Gill, Curran, H. Valerie, De Bono, Natalie, Rendell, Peter G. and Henry, Julie D.. (2021). Prospective memory deficits following acute alcohol consumption. Journal of Psychopharmacology. 35(11), pp. 1386-1397. https://doi.org/10.1177/02698811211056195
Dipendenza da alcol e sostanze
Rossetti, Maria Gloria, Crisanti, Camilla, Brambilla, Paolo and Lorenzetti, Valentina. (2021). Dipendenza da alcol e sostanze. In In Brambilla, Paolo (Ed.). Neuroscienze psichiatriche e computazionali pp. 272-285 Edizioni Minerva Medica.
Cannabis based medicines and cannabis dependence : A critical review of issues and evidence
Schlag, Anne K., Hindocha, Chandni, Zafar, Rayyan, Nutt, David J. and Curran, H. Valerie. (2021). Cannabis based medicines and cannabis dependence : A critical review of issues and evidence. Journal of Psychopharmacology. 35(7), pp. 773-785. https://doi.org/10.1177/0269881120986393
Cannabis, cannabinoids, and brain morphology : A review of the evidence
Chye, Yann, Kirkham, Rebecca, Lorenzetti, Valentina, McTavish, Eugene, Solowij, Nadia and Yücel, Murat. (2021). Cannabis, cannabinoids, and brain morphology : A review of the evidence. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 6(6), pp. 627-635. https://doi.org/10.1016/j.bpsc.2020.07.009
The acute and non-acute effects of cannabis on reward processing : A systematic review
Skumlien, Martine, Langley, Christelle, Lawn, Will, Voon, Valerie, Curran, H. Valerie, Roiser, Jonathan P. and Sahakian, Barbara J.. (2021). The acute and non-acute effects of cannabis on reward processing : A systematic review. Neuroscience and Biobehavioral Reviews. 130, pp. 512-528. https://doi.org/10.1016/j.neubiorev.2021.09.008
Supporting future cannabis policy – developing a standard joint unit : A brief back-casting exercise
López-Pelayo, Hugo, Matrai, Silvia, Balcells-Olivero, Mercè, Campeny, Eugènia, Braddick, Fleur, Bossong, Matthijs G., Cruz, Olga S., Deluca, Paolo, Dom, Geert, Feingold, Daniel, Freeman, Tom P., Guzman, Pablo, Hindocha, Chandni, Kelly, Brian C., Liebregts, Nienke, Lorenzetti, Valentina, Manthey, Jakob, Matias, João, Oliveras, Clara, ... Gual, Antoni. (2021). Supporting future cannabis policy – developing a standard joint unit : A brief back-casting exercise. Frontiers in Psychiatry. 12, p. Article: 675033. https://doi.org/10.3389/fpsyt.2021.675033
Mapping cortical and subcortical asymmetries in substance dependence : Findings from the ENIGMA Addiction Working Group
Cao, Zhipeng, Ottino-Gonzalez, Jonatan, Cupertino, Renata B., Schwab, Nathan, Hoke, Colin, Catherine, Orr, Cousijn, Janna, Dagher, Alain, Foxe, John J., Goudriaan, Anna E., Hester, Robert, Hutchison, Kent, Li, Chiang-Shan R., London, Edythe D., Lorenzetti, Valentina, Luijten, Maartje, Martin-Santos, Rocio, Momenan, Reza, Paulus, Martin P., ... Garavan, Hugh. (2021). Mapping cortical and subcortical asymmetries in substance dependence : Findings from the ENIGMA Addiction Working Group. Addiction Biology. 26, p. Article e13010. https://doi.org/10.1111/adb.13010
Illicit drug use and associated problems in the nightlife scene : A potential setting for prevention
Feltmann, Kristin, Elgán, Tobias H., Strandberg, Anna K., Kvillemo, Pia, Jayaram-Lindström, Nitya, Grabski, Meryem, Waldron, Jon, Freeman, Tom, Curran, Helen Valerie and Gripenberg, Johanna. (2021). Illicit drug use and associated problems in the nightlife scene : A potential setting for prevention. International Journal of Environmental Research and Public Health. 18(9), p. Article 4789. https://doi.org/10.3390/ijerph18094789
The effects of acute Δ9-tetrahydrocannabinol on striatal glutamatergic function : A proton magnetic resonance spectroscopy study
Bloomfield, Michael A. P., Petrilli, Katherine, Lees, Rachel, Hindocha, Chandni, Beck, Katherine, Turner, Ryan J., Onwordi, Ellis Chika, Rane, Neil, Lythgoe, David J., Stone, James M., Curran, H. Valerie, Howes, Oliver D. and Freeman, Tom P.. (2021). The effects of acute Δ9-tetrahydrocannabinol on striatal glutamatergic function : A proton magnetic resonance spectroscopy study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 6(6), pp. 660-667. https://doi.org/10.1016/j.bpsc.2021.04.013
Does variation in trait schizotypy and frequency of cannabis use influence the acute subjective, cognitive and psychotomimetic effects of delta-9-tetrahydrocannabinol? A mega-analysis
Freeman, Abigail M., Mokrysz, Claire, Hindocha, Chandni, Lawn, Will, Morgan, Celia J. A., Freeman, Tom P., Saunders, Rob and Curran, H. Valerie. (2021). Does variation in trait schizotypy and frequency of cannabis use influence the acute subjective, cognitive and psychotomimetic effects of delta-9-tetrahydrocannabinol? A mega-analysis. Journal of Psychopharmacology. 35(7), pp. 804-813. https://doi.org/10.1177/0269881120959601
Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users : A systematic review of fMRI studies
Sehl, Hannah, Terrett, Gill, Greenwood, Lisa-Marie, Kowalczyk, Magdalena, Thomson, Hannah, Poudel, Govinda, Manning, Victoria and Lorenzetti, Valentina. (2021). Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users : A systematic review of fMRI studies. Psychopharmacology. 238(10), pp. 2709-2728. https://doi.org/10.1007/s00213-021-05973-x
Sex differences in the neuroanatomy of alcohol dependence : Hippocampus and amygdala subregions in a sample of 966 people from the ENIGMA Addiction Working Group
Grace, Sally, Rossetti, Maria Gloria, Allen, Nicholas, Batalla, Albert, Bellani, Marcella, Brambilla, Paolo, Chye, Yann, Cousijn, Janna, Goudriaan, Anna E., Hester, Robert, Hutchison, Kent, Labuschagne, Izelle, Momenan, Reza, Martin-Santos, Rocio, Rendell, Peter, Solowij, Nadia, Sinha, Rajita, Li, Chiang-shan Ray, Schmaal, Lianne, ... Lorenzetti, Valentina. (2021). Sex differences in the neuroanatomy of alcohol dependence : Hippocampus and amygdala subregions in a sample of 966 people from the ENIGMA Addiction Working Group. Translational Psychiatry. 11(1), p. Article 156. https://doi.org/10.1038/s41398-021-01204-1
Sex and dependence related neuroanatomical differences in regular cannabis users : Findings from the ENIGMA Addiction Working Group
Rossetti, Maria Gloria, Mackey, Scott, Patalay, Praveetha, Allen, Nicholas B., Batalla, Albert, Bellani, Marcella, Chye, Yann, Conrod, Patricia, Cousijn, Janna, Garavan, Hugh, Goudriaan, Anna E., Hester, Robert, Martin-Santos, Rocio, Solowij, Nadia, Suo, Chao, Thompson, Paul M., Yücel, Murat, Brambilla, Paolo and Lorenzetti, Valentina. (2021). Sex and dependence related neuroanatomical differences in regular cannabis users : Findings from the ENIGMA Addiction Working Group. Translational Psychiatry. 11(1), p. Article 272. https://doi.org/10.1038/s41398-021-01382-y
Investigating the residual effects of chronic cannabis use and abstinence on verbal and visuospatial learning
Lorenzetti, Valentina, Takagi, Michael, van Dalen, Yvonne, Yücel, Murat and Solowij, Nadia. (2021). Investigating the residual effects of chronic cannabis use and abstinence on verbal and visuospatial learning. Frontiers in Psychiatry. 12, p. Article 663701. https://doi.org/10.3389/fpsyt.2021.663701
Gender-related neuroanatomical differences in alcohol dependence : Findings from the ENIGMA Addiction Working Group
Rossetti, Maria Gloria, Patalay, Praveetha, Mackey, Scott, Allen, Nicholas B., Batalla, Albert, Bellani, Marcella, Chye, Yann, Cousijn, Janna, Goudriaan, Anna E., Hester, Robert, Hutchison, Kent, Li, Chiang-Shan R., Martin-Santos, Rocio, Momenan, Reza, Sinha, Rajita, Schmaal, Lianne, Sjoerds, Zsuzsika, Solowij, Nadia, Suo, Chao, ... Lorenzetti, Valentina. (2021). Gender-related neuroanatomical differences in alcohol dependence : Findings from the ENIGMA Addiction Working Group. NeuroImage: Clinical. 30, p. Article 102636. https://doi.org/10.1016/j.nicl.2021.102636
Acute effects of cannabis on speech illusions and psychotic-like symptoms : Two studies testing the moderating effects of cannabidiol and adolescence
Mokrysz, Claire, Shaban, Natacha D. C., Freeman, Tom P., Lawn, Will, Pope, Rebecca A., Hindocha, Chandni, Freeman, Abigail, Wall, Matthew B., Bloomfield, Michael A. P., Morgan, Celia J. A., Nutt, David J. and Curran, H. Valerie. (2021). Acute effects of cannabis on speech illusions and psychotic-like symptoms : Two studies testing the moderating effects of cannabidiol and adolescence. Psychological Medicine. 51(12), pp. 2134-2142. https://doi.org/10.1017/S0033291720001038
Do comorbid personality disorders in cocaine dependence exacerbate neuroanatomical alterations? A structural neuroimaging study
Roberts, Carl A., Lorenzetti, Valentina, Albein-Urios, Natalia, Kowalczyk, Magdalena A., Martinez-Gonzalez, Jose M. and Verdejo-Garcia, Antonio. (2021). Do comorbid personality disorders in cocaine dependence exacerbate neuroanatomical alterations? A structural neuroimaging study. Progress in Neuropsychopharmacology and Biological Psychiatry. 110, p. 110298. https://doi.org/10.1016/j.pnpbp.2021.110298
Moving forwards with the standard THC unit [Commentary]
Freeman, Tom and Lorenzetti, Valentina. (2020). Moving forwards with the standard THC unit [Commentary] John Wiley & Sons Ltd. https://doi.org/10.1111/add.15107
Mapping and mitigating the health risks of legalizing recreational cannabis use : A call for synergy between research and policy
Hoch, Eva and Lorenzetti, Valentina. (2020). Mapping and mitigating the health risks of legalizing recreational cannabis use : A call for synergy between research and policy. World Psychiatry. 19(2), pp. 189-191. https://doi.org/10.1002/wps.20738
‘Standard THC units’ : A proposal to standardize dose across all cannabis products and methods of administration
Freeman, Tom P. and Lorenzetti, Valentina. (2020). ‘Standard THC units’ : A proposal to standardize dose across all cannabis products and methods of administration. Addiction. 115(7), pp. 1207-1216. https://doi.org/10.1111/add.14842
Ketamine as a mental health treatment : Are acute psychoactive effects associated with outcomes? A systematic review
Grabski, Meryem, Borissova, Anna, Marsh, Beth, Morgan, Celia J. A. and Curran, H. Valerie. (2020). Ketamine as a mental health treatment : Are acute psychoactive effects associated with outcomes? A systematic review. Behavioural Brain Research. 392, p. 112629. https://doi.org/10.1016/j.bbr.2020.112629
Neuroanatomical alterations in people with high and low cannabis dependence
Lorenzetti, Valentina, Chye, Yann, Suo, Chao, Walterfang, Mark, Lubman, Dan I., Takagi, Michael, Whittle, Sarah, Verdejo-Garcia, Antonio, Cousijn, Janna, Pantelis, Christos, Seal, Marc, Fornito, Alex, Yücel, Murat and Solowij, Nadia. (2020). Neuroanatomical alterations in people with high and low cannabis dependence. Australian and New Zealand Journal of Psychiatry. 54(1), pp. 68-75. https://doi.org/10.1177/0004867419859077
Young adults with higher motives and expectancies of regular cannabis use show poorer psychosocial functioning
Amiet, Danielle, Youssef, George J., Hagg, Lauryn J., Lorenzetti, Valentina, Parkes, Linden, Solowij, Nadia and Yücel, Murat. (2020). Young adults with higher motives and expectancies of regular cannabis use show poorer psychosocial functioning. Frontiers in Psychiatry. 11, p. 599365. https://doi.org/10.3389/fpsyt.2020.599365
The effects of acute cannabidiol on cerebral blood flow and its relationship to memory : An arterial spin labelling magnetic resonance imaging study
Bloomfield, Michael A. P., Green, Sebastian F., Hindocha, Chandni, Yamamori, Yumeya, Yim, Jocelyn Lok Ling, Jones, Augustus P. M., Walker, Hannah R., Tokarczuk, Pawel, Statton, Ben, Howes, Oliver D., Curran, H. Valerie and Freeman, Tom P.. (2020). The effects of acute cannabidiol on cerebral blood flow and its relationship to memory : An arterial spin labelling magnetic resonance imaging study. Journal of Psychopharmacology. 34(9), pp. 981-989. https://doi.org/10.1177/0269881120936419
The development and validation of a human screening model of tobacco abstinence
Grabski, Meryem, Curran, H. Valerie, Nutt, David J., Husbands, Stephen M., Ferguson, Stuart G. and Munafò, Marcus R.. (2020). The development and validation of a human screening model of tobacco abstinence. Drug and Alcohol Dependence. 206, p. 107720. https://doi.org/10.1016/j.drugalcdep.2019.107720
Medical cannabis in the UK : From principle to practice
Schlag, Anne Katrin, Baldwin, David S., Barnes, Michael, Bazire, Steve, Coathup, Rachel, Curran, H. Valerie, McShane, Rupert, Phillips, Lawrence D., Singh, Ilina and Nutt, David J.. (2020). Medical cannabis in the UK : From principle to practice. Journal of Psychopharmacology. 34(9), pp. 931-937. https://doi.org/10.1177/0269881120926677
Reduction in the occurrence of distressing involuntary memories following propranolol or hydrocortisone in healthy women
Kamboj, Sunjeev K., Gong, An Tong, Sim, ZhiHui, Rashid, Adrihani A., Baba, Ami, Iskandar, Georges, Das, Ravi K. and Curran, H. Valerie. (2020). Reduction in the occurrence of distressing involuntary memories following propranolol or hydrocortisone in healthy women. Psychological Medicine. 50(7), pp. 1148-1155. https://doi.org/10.1017/S0033291719001028
Cannabidiol for the treatment of cannabis use disorder : A phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial
Freeman, Tom P., Hindocha, Chandni, Baio, Gianluca, Shaban, Natacha D. C., Thomas, Emily M., Astbury, Danica, Freeman, Abigail M., Lees, Rachel, Craft, Sam, Morrison, Paul D., Bloomfield, Michael A. P., O'Ryan, Dominic, Kinghorn, Jane, Morgan, Celia J. A., Mofeez, Ali and Curran, H. Valerie. (2020). Cannabidiol for the treatment of cannabis use disorder : A phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial. The Lancet Psychiatry. 7(10), pp. 865-874. https://doi.org/10.1016/S2215-0366(20)30290-X
How do online and offline sampling compare in a multinational study of drug use and nightlife behaviour?
Waldron, Jon, Grabski, Meryem, Freeman, Tom P., Mokrysz, Claire, Hindocha, Chandni, Measham, Fiona, van Beek, Ruben, van der Pol, Peggy, Hauspie, Bert, Dirkx, Nicky, Schrooten, Jochen, Elgán, Tobias H., Feltmann, Kristin, Benedetti, Elisa, Tomba, Gianpaolo Scalia, Fabi, Francesco, Molinaro, Sabrina, Gripenberg, Johanna, van Havere, Tina, ... Curran, H. Valerie. (2020). How do online and offline sampling compare in a multinational study of drug use and nightlife behaviour? International Journal of Drug Policy. 82, p. 102812. https://doi.org/10.1016/j.drugpo.2020.102812
Unpacking common and distinct neuroanatomical alterations in cocaine dependent versus pathological gambling
Irizar, Patricia, Albein-Urios, Natalia, Martínez-González, José Miguel, Verdejo-Garcia, Antonio and Lorenzetti, Valentina. (2020). Unpacking common and distinct neuroanatomical alterations in cocaine dependent versus pathological gambling. European Neuropsychopharmacology. 33, pp. 81-88. https://doi.org/10.1016/j.euroneuro.2020.01.019
The acute effects of cannabidiol on the neural correlates of reward anticipation and feedback in healthy volunteers
Lawn, Will, Hill, James, Hindocha, Chandni, Yim, Jocelyn, Yamamori, Yumeya, Jones, Gus, Walker, Hannah, Green, Sebastian F., Wall, Matthew B., Howes, Oliver D., Curran, H. Valerie, Freeman, Tom P. and Bloomfield, Michael A. P.. (2020). The acute effects of cannabidiol on the neural correlates of reward anticipation and feedback in healthy volunteers. Journal of Psychopharmacology. 34(9), pp. 969-980. https://doi.org/10.1177/0269881120944148
Predicting alcohol dependence from multi-site brain structural measures
Hahn, Sage, Mackey, Scott, Cousijn, Janna, Foxe, John J., Heinz, Andreas, Hester, Robert, Hutchinson, Kent, Kiefer, Falk, Korucuoglu, Ozlem, Lett, Tristram, Li, Chiang-Shan R., London, Edythe, Lorenzetti, Valentina, Maartje, Luijten, Momenan, Reza, Orr, Catherine, Paulus, Martin, Schmaal, Lianne, Sinha, Rajita, ... Garavan, Hugh. (2020). Predicting alcohol dependence from multi-site brain structural measures. Human Brain Mapping. pp. 1-11. https://doi.org/10.1002/hbm.25248
Pineal gland volume in major depressive and bipolar disorders
Takahashi, Tsutomu, Sasabayashi, Daiki, Yücel, Murat, Whittle, Sarah, Lorenzetti, Valentina, Walterfang, Mark, Suzuki, Michio, Pantelis, Christos, Malhi, Gin S. and Allen, Nicholas B.. (2020). Pineal gland volume in major depressive and bipolar disorders. Frontiers in Psychiatry. 11, p. 450. https://doi.org/10.3389/fpsyt.2020.00450
Neural correlates of symptom severity in obsessive-compulsive disorder using magnetization transfer and diffusion tensor imaging
Maleki, Suzan, Chye, Yann, Zhang, Xiaoliu, Parkes, Linden, Chamberlain, Samuel R., Fontenelle, Leonardo F., Braganza, Leah, Youssef, George, Lorenzetti, Valentina, Harrison, Ben J., Yücel, Murat and Suo, Chao. (2020). Neural correlates of symptom severity in obsessive-compulsive disorder using magnetization transfer and diffusion tensor imaging. Psychiatry Research: Neuroimaging. 298, p. Article 111046. https://doi.org/10.1016/j.pscychresns.2020.111046
Brain-derived neurotrophic factor association with amygdala response in major depressive disorder
Lorenzetti, Valentina, Costafreda, Sergi G., Rimmer, Rachael M., Rasenick, Mark M., Marangell, Lauren B. and Fu, Cynthia H. Y.. (2020). Brain-derived neurotrophic factor association with amygdala response in major depressive disorder. Journal of Affective Disorders. 267, pp. 103-106. https://doi.org/10.1016/j.jad.2020.01.159
Adolescent cannabis use, cognition, brain health and educational outcomes : A review of the evidence
Lorenzetti, Valentina, Hoch, Eva and Hall, Wayne. (2020). Adolescent cannabis use, cognition, brain health and educational outcomes : A review of the evidence. European Neuropsychopharmacology. 36, pp. 169-180. https://doi.org/10.1016/j.euroneuro.2020.03.012
Accuracy of automated amygdala MRI segmentation approaches in Huntington's disease in the IMAGE-HD cohort
Alexander, Bonnie, Georgiou-Karistianis, Nellie, Beare, Richard, Ahveninen, Lotta M., Lorenzetti, Valentina, Stout, Julie C. and Glikmann-Johnston, Yifat. (2020). Accuracy of automated amygdala MRI segmentation approaches in Huntington's disease in the IMAGE-HD cohort. Human Brain Mapping. 41(7), pp. 1875-1888. https://doi.org/10.1002/hbm.24918
Subcortical surface morphometry in substance dependence : An ENIGMA addiction working group study
Chye, Yann, Mackey, Scott, Gutman, Boris A., Ching, Christopher R. K., Batalla, Albert, Blaine, Sara, Brooks, Samantha, Caparelli, Elisabeth C., Cousijn, Janna, Dagher, Alain, Foxe, John J., Goudriaan, Anna E., Hester, Robert, Hutchison, Kent, Jahanshad, Neda, Kaag, Anne M., Korucuoglu, Ozlem, Li, Chiang-Shan R., London, Edythe D., ... Garavan, Hugh. (2020). Subcortical surface morphometry in substance dependence : An ENIGMA addiction working group study. Addiction Biology. 25(6), p. e12830. https://doi.org/10.1111/adb.12830
Social cognition impairments in long-term opiate users in treatment
Terrett, Gill, Mercuri, Kimberly, Pizarro-Campagna, Elizabeth, Hugrass, Laila, Curran, H. Valerie, Henry, Julie D. and RendeRendell, Peter G.ll, P.. (2020). Social cognition impairments in long-term opiate users in treatment. Journal of Psychopharmacology. 34(2), pp. 254-263. https://doi.org/10.1177/0269881119875981
Value-based decision-making of cigarette and nondrug rewards in dependent and occasional cigarette smokers: An FMRI study
Lawn, Will, Mithchener, Ludo, Freeman, Tom P., Benattayallah, Abdelmalek, Bisby, James A., Wall, Matthew B., Dodds, Chris M., Curran, Helen V. and Morgan, Celia J.A.. (2020). Value-based decision-making of cigarette and nondrug rewards in dependent and occasional cigarette smokers: An FMRI study. Addiction Biology. 25(4), pp. 1 - 12. https://doi.org/10.1111/adb.12802
Acute effects of cannabinoids on addiction endophenotypes are moderated by genes encoding the CB1 receptor and FAAH enzyme
Hindocha, Chandni, Freeman, Tom P., Schafer, Grainne, Gardner, Chelsea, Bloomfield, Michael A. P., Bramon, Elvira, Morgan, Celia J.A. and Curran, Helen Valerie. (2020). Acute effects of cannabinoids on addiction endophenotypes are moderated by genes encoding the CB1 receptor and FAAH enzyme. Addiction Biology. 25(3), pp. 1 - 11. https://doi.org/10.1111/adb.12762
Cannabis use and mental health : Risks and benefits [Editorial]
Hall, Wayne, Hoch, Eva and Lorenzetti, Valentina. (2019). Cannabis use and mental health : Risks and benefits [Editorial]. European Archives of Psychiatry and Clinical Neuroscience. 269, pp. 1-3. https://doi.org/10.1007/s00406-019-00986-2
Neuroanatomical alterations in people with high and low cannabis dependence
Lorenzetti, Valentina, Chye, Yann, Suo, Chao, Walterfang, Mark, Lubman, Dan I., Takagi, Michael, Whittle, Sarah, Verdejo-Garcia, Antonio, Cousijn, Janna, Pantelis, Christos, Seal, Marc, Fornito, Alex, Yücel, Murat and Solowij, Nadia. (2019). Neuroanatomical alterations in people with high and low cannabis dependence. Australian and New Zealand Journal of Psychiatry. 54(1), pp. 68-75. https://doi.org/10.1177/0004867419859077
A roadmap for integrating neuroscience into addiction treatment : A consensus of the neuroscience interest group of the international society of addiction medicine
Verdejo-Garcia, Antonio, Lorenzetti, Valentina, Manning, Victoria, Piercy, Hugh, Bruno, Raimondo, Hester, Rob, Pennington, David, Tolomeo, Serenella, Arunogiri, Shalini, Bates, Marsha E., Bowden-Jones, Henrietta, Campanella, Salvatore, Daughters, Stacey B., Kouimtsidis, Christos, Lubman, Dan I., Meyerhoff, Dieter J., Ralph, Annaketurah, Rezapour, Tara, Tavakoli, Hosna, ... Ekhtiari, Hamed. (2019). A roadmap for integrating neuroscience into addiction treatment : A consensus of the neuroscience interest group of the international society of addiction medicine. Frontiers in Psychiatry. 10, p. Article 877. https://doi.org/10.3389/fpsyt.2019.00877
What are the psychological effects of using synthetic cannabinoids? A systematic review
Akram, Hina, Mokrysz, Claire and Curran, H. Valerie. (2019). What are the psychological effects of using synthetic cannabinoids? A systematic review. Journal of Psychopharmacology. 33(3), pp. 271-283. https://doi.org/10.1177/0269881119826592
Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories
Das, Ravi K., Gale, Grace, Walsh, Katie, Hennessy, Vanessa E., Iskandar, Georges, Mordecai, Luke A., Brandner, Brigitta, Kindt, Merel, Curran, H. Valerie and Kamboj, Sunjeev K.. (2019). Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories. Nature Communications. 10(1), p. 5187. https://doi.org/10.1038/s41467-019-13162-w
How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review
Freeman, Abigail M., Petrilli, Katherine, Lees, Rachel, Hindocha, Chandni, Mokrysz, Claire, Curran, H. Valerie, Saunders, Rob and Freeman, Tom P.. (2019). How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review. Neuroscience and Biobehavioral Reviews. 107, pp. 696-712. https://doi.org/10.1016/j.neubiorev.2019.09.036
Defining compulsive behavior
Luigjes, Judy, Lorenzetti, Valentina, de Haan, Sanneke, Youssef, George J., Murawski, Carsten, Sjoerds, Zsuzsika, van den Brink, Wim, Denys, Damiaan, Fontenelle, Leonardo F. and Yücel, Murat. (2019). Defining compulsive behavior. Neuropsychology Review. 29(1), pp. 4-13. https://doi.org/10.1007/s11065-019-09404-9
Which biological and self-report measures of cannabis use predict cannabis dependency and acute psychotic-like effects?
Curran, H. Valerie, Hindocha, Chandni, Morgan, Celia J. A., Shaban, Natacha, Das, Ravi K. and Freeman, Tom P.. (2019). Which biological and self-report measures of cannabis use predict cannabis dependency and acute psychotic-like effects? Psychological Medicine. 49(9), pp. 1574-1580. https://doi.org/10.1017/S003329171800226X
Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits
Parkes, Linden, Tiego, Jeggan, Aquino, Kevin, Braganza, Leah, Chamberlain, Samuel R., Fontenelle, Leonardo F., Harrison, Ben J., Lorenzetti, Valentina, Paton, Bryan, Razi, Adeel, Fornito, Alex and Yücel, Murat. (2019). Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits. NeuroImage. 202, p. 116070. https://doi.org/10.1016/j.neuroimage.2019.116070
Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity
Wall, Matthew B., Pope, Rebecca, Freeman, Tom P., Kowalczyk, Oliwia S., Demetriou, Lysia, Mokrysz, Claire, Hindocha, Chandni, Lawn, Will, Bloomfield, Michael A. P., Freeman, Abigail M., Feilding, Amanda, Nutt, David and Curran, H. Valerie. (2019). Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity. Journal of Psychopharmacology. 33(7), pp. 822-830. https://doi.org/10.1177/0269881119841568
Does regular cannabis use affect neuroanatomy? An updated systematic review and meta-analysis of structural neuroimaging studies
Lorenzetti, Valentina, Chye, Yann, Silva, Pedro, Solowij, Nadia and Roberts, Carl A.. (2019). Does regular cannabis use affect neuroanatomy? An updated systematic review and meta-analysis of structural neuroimaging studies. European Archives of Psychiatry and Clinical Neuroscience. 269(1), pp. 59 - 71. https://doi.org/10.1007/s00406-019-00979-1
Mega-analysis of gray matter volume in substance dependence: General and substance-specific regional effects
Mackey, Scott, Allgaier, Nicholas, Chaarani, Bader, Spechler, Philip, Orr, Catherine, Bunn, Janice, Allen, Nicholas B., Alia-Klein, Nelly, Batalla, Albert, Blaine, Sara K., Brooks, Samantha, Caparelli, Elisabeth C., Chye, Yann Ying, Cousijn, Janna, Dagher, Alain, Desrivieres, Sylvane, Feldstein-Ewing, Sarah W., Foxe, John J., Goldstein, Rita Z., ... Garavan, Hugh. (2019). Mega-analysis of gray matter volume in substance dependence: General and substance-specific regional effects. American Journal of Psychiatry. 176(2), pp. 119 - 128. https://doi.org/10.1176/appi.ajp.2018.17040415
From socioeconomic disadvantage to obesity: The mediating role of psychological distress and emotional eating
Spinosa, Jade, Christiansen, Paul, Dickson, Joanne M., Lorenzetti, Valentina and Hardman, Charlotte A.. (2019). From socioeconomic disadvantage to obesity: The mediating role of psychological distress and emotional eating. Obesity. 27(4), pp. 559 - 564. https://doi.org/10.1002/oby.22402
Impulsivity and body fat accumulation are linked to cortical and subcortical brain volumes among adolescents and adults
Kakoschke, Naomi, Lorenzetti, Valentina, Caeyenberghs, Karen and Verdejo-García, Antonio. (2019). Impulsivity and body fat accumulation are linked to cortical and subcortical brain volumes among adolescents and adults. Scientific Reports. 9(1), pp. 1 - 11. https://doi.org/10.1038/s41598-019-38846-7
Alteration to hippocampal volume and shape confined to cannabis dependence: A multi-site study
Chye, Yann, Lorenzetti, Valentina, Suo, Chao, Batalla, Albert, Cousijn, Janna, Goudriaan, Anna E., Jenkinson, Mark, Martin-Santos, Rocio, Whittle, Sarah, Yücel, Murat and Solowij, Nadia. (2019). Alteration to hippocampal volume and shape confined to cannabis dependence: A multi-site study. Addiction Biology. 24(4), pp. 822 - 834. https://doi.org/10.1111/adb.12652
Post-traumatic stress disorder in victims of sexual assault with pre-assault substance consumption: A systematic review
Gong, An Tong, Kamboj, Sunjeev K. and Curran, Helen Valerie. (2019). Post-traumatic stress disorder in victims of sexual assault with pre-assault substance consumption: A systematic review. Frontiers in Psychiatry. 10, pp. 1 - 18. https://doi.org/10.3389/fpsyt.2019.00092
Cortical surface morphology in long-term cannabis users: A multi-site MRI study
Chye, Yann, Suo, Chao, Lorenzetti, Valentina, Batalla, Albert, Cousijn, Janna, Goudriaan, Anna E., Martin-Santos, Rocio, Whittle, Sarah, Solowij, Nadia and Yücel, Murat. (2019). Cortical surface morphology in long-term cannabis users: A multi-site MRI study. European Neuropsychopharmacology. 29(2), pp. 257 - 265. https://doi.org/10.1016/j.euroneuro.2018.11.1110
Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS) : A randomised, controlled, double-blind trial
Howard, Robert, Cort, Elizabeth, Bradley, Rosie, Harper, Emma, Kelly, Linda, Bentham, Peter, Ritchie, Craig, Reeves, Suzanne, Fawzi, Waleed, Livingston, Gill, Sommerlad, Andrew, Oomman, Sabu, Nazir, Ejaz, Nilforooshan, Ramin, Barber, Robert, Fox, Chris, Macharouthu, Ajay Verma, Ramachandra, Pranathi, Pattan, Vivek, ... Gray, Richard. (2018). Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS) : A randomised, controlled, double-blind trial. The Lancet Psychiatry. 5(7), pp. 553-563. https://doi.org/10.1016/S2215-0366(18)30141-X
The effects of cannabidiol on impulsivity and memory during abstinence in cigarette dependent smokers 
Chandni Hindocha, Tom P. Freeman, Meryem Grabski, H. Crudgington, A.C. Davies, J.B. Stroud, Ravi K. Das, Will Lawn, Celia Morgan and H. Valerie Curran. (2018). The effects of cannabidiol on impulsivity and memory during abstinence in cigarette dependent smokers . Scientific Reports. 8(7568), pp. 1-7. https://doi.org/10.1038/s41598-018-25846-2
The acute effects of a dopamine d3 receptor preferring agonist on motivation for cigarettes in dependent and occasional cigarette smokers
Will Lawn, Tom P. Freeman, Katie East, Annie Gaule, Elizabeth R. Aston, M. A P Bloomfield, Ravi K. Das, Celia Morgan and H. Valerie Curran. (2018). The acute effects of a dopamine d3 receptor preferring agonist on motivation for cigarettes in dependent and occasional cigarette smokers. Nicotine and Tobacco Research. 20(7), pp. 800-809. https://doi.org/10.1093/ntr/ntx159
Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression
J.B. Stroud, Tom P. Freeman, Robert Leech, Chandni Hindocha, Will Lawn, D.J. Nutt, H. V. Curran and R. L. Carhart-Harris. (2018). Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression. Psychopharmacology. 235(2), pp. 459-466. https://doi.org/10.1007/s00213-017-4754-y
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
R. L. Carhart-Harris, M. Bolstridge, C.M.J. Day, J. Rucker, R. Watts, David Erritzoe, M. Kaelen, B. Giribaldi, M. A P Bloomfield, S. Pilling, J.A. Rickard, B. Forbes, A. Feilding, D. Taylor, H. V. Curran and D.J. Nutt. (2018). Psilocybin with psychological support for treatment-resistant depression: six-month follow-up. Psychopharmacology. 235(2), pp. 399-408. https://doi.org/10.1007/s00213-017-4771-x
Non-dependent and dependent daily cannabis users differ in mental health but not prospective memory ability
Ruth Braidwood, Samantha Mansell, Jon Waldron, Peter Rendell, Sunjeev Kamboj and H. Valerie Curran. (2018). Non-dependent and dependent daily cannabis users differ in mental health but not prospective memory ability. Frontiers in Psychiatry. 9(97), pp. 1-9. https://doi.org/10.3389/fpsyt.2018.00097
Individual and combined effects of acute delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic symptoms and memory function
Celia Morgan, Tom P. Freeman, Chandni Hindocha, Grainne Schafer, Chelsea Gardner and H. Valerie Curran. (2018). Individual and combined effects of acute delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic symptoms and memory function. Translational Psychiatry (online). 8(1), pp. 1-10. https://doi.org/10.1038/s41398-018-0191-x
Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion
Tom P. Freeman, Rebecca A. Pope, Matthew B. Wall, James A. Bisby, Maartje Luijten, Chandni Hindocha, Claire Mokrysz, Will Lawn, Abigail Moss, Michael A. P. Bloomfield, Celia J. A. Morgan, David J. Nutt and H. Valerie Curran. (2018). Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion. International Journal of Neuropsychopharmacology. 21(1), pp. 21-32. https://doi.org/10.1093/ijnp/pyx082
Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal
Chandni Hindocha, Tom P. Freeman, Meryem Grabsk, Jack B. Stroud, Holly Crudgington, Alan C. Davies, Ravi K. Das, William Lawn, Celia Morgan and H. Valerie Curran. (2018). Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal. Addiction. 113(9), pp. 1696-1705. https://doi.org/10.1111/add.14243
Reduced amygdala volumes are related to motor and cognitive signs in Huntington's disease: The IMAGE-HD study
Ahveninen, Lotta M., Stout, Julie C., Georgiou-Karistianis, Nellie, Lorenzetti, Valentina and Glikmann-Johnston, Yifat. (2018). Reduced amygdala volumes are related to motor and cognitive signs in Huntington's disease: The IMAGE-HD study. NeuroImage: Clinical. 18, pp. 881 - 887. https://doi.org/10.1016/j.nicl.2018.03.027
The anticipation and outcome phases of reward and loss processing: A neuroimaging meta-analysis of the monetary incentive delay task
Oldham, Stuart, Murawski, Carsten, Fornito, Alex, Youssef, George J., Yücel, Murat and Lorenzetti, Valentina. (2018). The anticipation and outcome phases of reward and loss processing: A neuroimaging meta-analysis of the monetary incentive delay task. Human Brain Mapping. 39(8), pp. 3398 - 3418. https://doi.org/10.1002/hbm.24184
Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
Destrée, Louise, Amiet, Danielle, Carter, Adrian, Lee, Rico, Lorenzetti, Valentina, Segrave, Rebecca, Youssef, George, Solowij, Nadia and Yücel, Murat. (2018). Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA. Drugs in Context. 7, pp. 1 - 5. https://doi.org/10.7573/dic.212541
Emotion regulation using virtual environments and real-time fMRI neurofeedback
Lorenzetti, Valentina, Melo, Bruno, Basílio, Rodrigo, Suo, Chao, Yücel, Murat, Tierra-Criollo, Carlos J. and Moll, Jorge. (2018). Emotion regulation using virtual environments and real-time fMRI neurofeedback. Frontiers in Neurology. 9, pp. 1 - 15. https://doi.org/10.3389/fneur.2018.00390
Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium
Kong, Xiang-Zhen, Mathias, Samuel R., Guadalupe, Tulio, ENIGMA Laterality Working Group,, Glahn, David C., Franke, Barbara, Crivello, Fabrice, Tzourio-Mazoyer, Nathalie, Fisher, Simon E., Thompson, Paul M., Francks, Clyde, Lorenzetti, Valentina and ENIGMA Laterality Working Group. (2018). Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium. Proceedings of the National Academy of Sciences of USA. 115(22), pp. E5154 - E5163. https://doi.org/10.1073/pnas.1718418115
A systematic review and meta-analysis of the neural correlates of psychological therapies in major depression
Sankar, Anjali, Melin, Alice, Lorenzetti, Valentina, Horton, Paul, Costafreda, Sergi G. and Fu, Cynthia H. Y.. (2018). A systematic review and meta-analysis of the neural correlates of psychological therapies in major depression. Psychiatry Research: Neuroimaging. 279, pp. 31 - 39. https://doi.org/10.1016/j.pscychresns.2018.07.002
Amisulpride for very late-onset schizophrenia-like psychosis: The ATLAS three-arm RCT
Howard, Robert, Cort, Elizabeth, Bradley, Rosie, Harper, Emma, Kelly, Linda, Bentham, Peter, Ritchie, Craig, Reeves, Suzanne, Fawzi, Waleed, Livingston, Gill, Sommerlad, Andrew, Oomman, Sabu, Nazir, Ejaz, Nilforooshan, Ramin, Barber, Robert, Fox, Chris, Macharouthu, Ajay, Ramachandra, Pranathi, Pattan, Vivek, ... Gray, Richard. (2018). Amisulpride for very late-onset schizophrenia-like psychosis: The ATLAS three-arm RCT. Health Technology Assessment. 22(67), pp. 1 - 60. https://doi.org/10.3310/hta22670
A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study
Yucel, Murat, Oldenhof, Erin, Ahmed, Serge H., Belin, David, Billieux, Joel, Bowden-Jones, Henrietta, Carter, Adrian, Chamberlain, Samuel R., Clark, Luke, Connor, Jason P., Daglish, Mark, Dom, Geert, Dannon, Pinhas, Duka, Theodora, Fernandez-Serrano, Maria Jose, Field, Matt, Franken, Ingmar, Goldstein, Rita Z., Gonzalez, Raul, ... Verdejo-Garcia, Antonio. (2018). A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study. Addiction. 114(6), pp. 1095 - 1109. https://doi.org/10.1111/add.14424
Unpacking the role of self-reported compulsivity and impulsivity in obsessive-compulsive disorder
Prochazkova, Luisa, Parkes, Linden, Dawson, Andrew, Youssef, George J., Ferreira, Gabriela M., Lorenzetti, Valentina, Segrave, Rebecca A., Fontenelle, Leonardo F. and Yücel, Murat. (2018). Unpacking the role of self-reported compulsivity and impulsivity in obsessive-compulsive disorder. CNS Spectrums. 23(1), pp. 51 - 58. https://doi.org/10.1017/S1092852917000244
Ketamine treatment for depression : Opportunities for clinical innovation and ethical foresight
Singh, Ilina, Morgan, Celia, Curran, Valerie, Nutt, David, Schlag, Anne and McShane, Rupert. (2017). Ketamine treatment for depression : Opportunities for clinical innovation and ethical foresight. The Lancet Psychiatry. 4(5), pp. 419-426. https://doi.org/10.1016/S2215-0366(17)30102-5
Anatomy of a Joint: Comparing Self-Reported and Actual Dose of Cannabis and Tobacco in a Joint, and How These Are Influenced by Controlled Acute Administration
Chandni Hindocha, Tom P. Freeman and H. Valerie Curran. (2017). Anatomy of a Joint: Comparing Self-Reported and Actual Dose of Cannabis and Tobacco in a Joint, and How These Are Influenced by Controlled Acute Administration. Cannabis and Cannabinoid Research. 2(1), pp. 217-223. https://doi.org/10.1089/can.2017.0024
Neuroscience in gambling policy and treatment: an interdisciplinary perspective
Murat Yucel, Adrian Carter, Amy R Allen, Bernard Balleine, Luke Clark, Nicki A Dowling, Sally M Gainsbury, Anna E Goudriaan, Jon Grant, Alan Hayes, David Hodgins, Ruth van Holst, Ralph Lattimore, Charles Livingstone, Valentina Lorenzetti, Dan Lubman, Carsten Murawski, Linden Parkes, Nancy Petry, ... Wayne Hall. (2017). Neuroscience in gambling policy and treatment: an interdisciplinary perspective. The Lancet Psychiatry. 4(6), pp. 501-506. https://doi.org/10.1016/S2215-0366(16)30369-8
Orbitofrontal and caudate volumes in cannabis users: A multi-site mega-analysis comparing dependent versus non-dependent users
Chye, Yann, Solowij, Nadia, Suo, Chao, Batalla, Albert, Cousijn, Janna, Goudriaan, Anna E., Martin-Santos, Rocio, Whittle, Sarah, Lorenzetti, Valentina and Yücel, Murat. (2017). Orbitofrontal and caudate volumes in cannabis users: A multi-site mega-analysis comparing dependent versus non-dependent users. Psychopharmacology. 234(13), pp. 1985 - 1995. https://doi.org/10.1007/s00213-017-4606-9
Cannabis-related hippocampal volumetric abnormalities specific to subregions in dependent users
Chye, Yann, Suo, Chao, Yücel, Murat, den Ouden, Lauren, Solowij, Nadia and Lorenzetti, Valentina. (2017). Cannabis-related hippocampal volumetric abnormalities specific to subregions in dependent users. Psychopharmacology. 234(14), pp. 2149 - 2157. https://doi.org/10.1007/s00213-017-4620-y
Acute memory and psychotomimetic effects of cannabis and tobacco both 'joint' and individually: A placebo-controlled trial
Hindocha, Chandni, Freeman, T. P., Xia, J. X., Shaban, Natacha D. C. and Curran, Helen V.. (2017). Acute memory and psychotomimetic effects of cannabis and tobacco both 'joint' and individually: A placebo-controlled trial. Psychological Medicine. 47(15), pp. 2708 - 2719. https://doi.org/10.1017/S0033291717001222
A psychometric validation study of the Impulsive-Compulsive Behaviours Checklist: A transdiagnostic tool for addictive and compulsive behaviours
Guo, Karen, Youssef, George J., Dawson, Andrew, Parkes, Linden, Oostermeijer, Sanne, López-Solà, Clara, Lorenzetti, Valentina, Greenwood, Christopher, Fontenelle, Leonardo F. and Yücel, Murat. (2017). A psychometric validation study of the Impulsive-Compulsive Behaviours Checklist: A transdiagnostic tool for addictive and compulsive behaviours. Addictive Behaviors. 67, pp. 26 - 33. https://doi.org/10.1016/j.addbeh.2016.11.021
Longitudinal study of hippocampal volumes in heavy cannabis users
Koenders, L., Lorenzetti, Valentina, de Haan, L., Suo, C., Vingerhoets, W. A. M., van den Brink, W., Wiers, R. W., Meijer, C. J., MacHielsen, M. W. J., Goudriaan, Anna E., Veltman, D. J., Yücel, Murat and Cousijn, Janna. (2017). Longitudinal study of hippocampal volumes in heavy cannabis users. Journal of Psychopharmacology. 31(8), pp. 1027 - 1034. https://doi.org/10.1177/0269881117718380
Role of orbitofrontal sulcogyral pattern on lifetime cannabis use and depressive symptoms
Chye, Yann, Solowij, Nadia, Ganella, Eleni P., Suo, Chao, Yücel, Murat, Batalla, Albert, Cousijn, Janna, Goudriaan, Anna E., Martin-Santos, Rocio, Whittle, Sarah, Bartholomeusz, Cali F. and Lorenzetti, Valentina. (2017). Role of orbitofrontal sulcogyral pattern on lifetime cannabis use and depressive symptoms. Progress in Neuropsychopharmacology and Biological Psychiatry. 79, pp. 392 - 400. https://doi.org/10.1016/j.pnpbp.2017.07.017
Investigating the role of anticipatory reward and habit strength in obsessive-compulsive disorder
Ferreira, Gabriela M., Yücel, Murat, Dawson, Andrew, Lorenzetti, Valentina and Fontenelle, Leonardo F.. (2017). Investigating the role of anticipatory reward and habit strength in obsessive-compulsive disorder. CNS Spectrums. 22(3), pp. 295 - 304. https://doi.org/10.1017/S1092852916000535
Neuroimaging of the human brain in adolescent substance users
Takagi, Michael, Youssef, George and Lorenzetti, Valentina. (2016). Neuroimaging of the human brain in adolescent substance users. In In De Micheli, Denise, Andrade, André Luiz Monezi, da Silva, Eroy Aparecida and de Souza Formigoni, Maria Lucia Oliveira (Ed.). Drug abuse in adolescence : Neurobiological, cognitive, and psychological issues pp. 69-99 Springer. https://doi.org/10.1007/978-3-319-17795-3_6
Cannabis use disorders and altered brain morphology : Where is the evidence?
Lorenzetti, Valentina, Batalla, Albert and Cousijn, Janna. (2016). Cannabis use disorders and altered brain morphology : Where is the evidence? Current Addiction Reports. 3(2), pp. 189-198. https://doi.org/10.1007/s40429-016-0102-2
Editorial : Reporting guidelines for psychopharmacology
Steckler, Thomas, Curran, H. Valerie, de Wit, Harriet, Howes, Oliver, Hoyer, Daniel, Lucki, Irwin, Miczek, Klaus A., Morrow, A. Leslie, Price, Lawrence H. and Robbins, Trevor W.. (2016). Editorial : Reporting guidelines for psychopharmacology. Psychopharmacology. 233(7), pp. 1131-1134. https://doi.org/10.1007/s00213-016-4252-7
The neurobiology of cannabis use disorders: A call for evidence
Valentina Lorenzetti, Janna Cousijn, Nadia Solowij, Hugh Garavan, Chao Suo, Murat Yucel and Antonio Verdejo-Garcia. (2016). The neurobiology of cannabis use disorders: A call for evidence. Frontiers in Behavioral Neuroscience. 10, pp. 1-3. https://doi.org/10.3389/fnbeh.2016.00086
Olfactory sulcus morphology in patients with current and past major depression
Takahashi, Tsutomu, Nishikawa, Yumiko, Yücel, Murat, Whittle, Sarah, Lorenzetti, Valentina, Walterfang, Mark, Sasabayashi, Daiki, Suzuki, Michio, Pantelis, Christos and Allen, Nicholas B.. (2016). Olfactory sulcus morphology in patients with current and past major depression. Psychiatry Research: Neuroimaging. 255, pp. 60 - 65. https://doi.org/10.1016/j.pscychresns.2016.07.008
AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers
Morgan, Celia J. A., Freeman, T. P., Powell, J. and Curran, Helen V.. (2016). AKT1 genotype moderates the acute psychotomimetic effects of naturalistically smoked cannabis in young cannabis smokers. Translational Psychiatry. 6(2), pp. 1 - 6. https://doi.org/10.1038/tp.2015.219
Genetic imaging consortium for addiction medicine: From neuroimaging to genes
Mackey, Scott, Kan, Kees-Jan, Chaarani, Bader, Alia-Klein, Nelly, Batalla, Albert, Brooks, Samantha, Cousijn, Janna, Dagher, Alain, de Ruiter, Michiel, Desrivieres, Sylvane, Feldstein Ewing, Sarah W., Goldstein, Rita Z., Goudriaan, Anna E., Heitzeg, Mary M., Hutchison, Kent, Li, Chiang-Shan R., London, Edythe D., Lorenzetti, Valentina, Luijten, Maartje, ... Conrod, Patricia. (2016). Genetic imaging consortium for addiction medicine: From neuroimaging to genes. In Neuroscience for addiction medicine: From prevention to rehabilitation - methods and interventions pp. 203 - 223 Elsevier. https://doi.org/10.1016/bs.pbr.2015.07.026
Deconstructing the nature of episodic foresight deficits associated with chronic opiate use
Mercuri, Kimberly, Terrett, Gill, Bailey, Phoebe E., Henry, Julie D., Curran, Helen Valerie and Rendell, Peter G.. (2016). Deconstructing the nature of episodic foresight deficits associated with chronic opiate use. British Journal of Clinical Psychology. 55(4), pp. 401 - 413. https://doi.org/10.1111/bjc.12110
Are adolescents more vulnerable to the harmful effects of cannabis than adults? A placebo-controlled study in human males
Mokrysz, Claire, Freeman, Tom P., Korkki, S., Griffiths, K. and Curran, Helen V.. (2016). Are adolescents more vulnerable to the harmful effects of cannabis than adults? A placebo-controlled study in human males. Translational Psychiatry. 6(11), pp. 1 - 10. https://doi.org/10.1038/tp.2016.225
Adolescent cannabis use: What is the evidence for functional brain alteration?
Lorenzetti, Valentina, Alonso-Lana, Silvia, Youssef, G. J., Verdejo-Garcia, Antonio, Suo, Chao, Cousijn, Janna, Takagi, Michael, Yucel, Murat and Solowij, Nadia. (2016). Adolescent cannabis use: What is the evidence for functional brain alteration? Current Pharmaceutical Design. 22(42), pp. 6353 - 6365. https://doi.org/10.2174/1381612822666160805155922
The role of cannabinoids in neuroanatomic alterations in cannabis users
Lorenzetti, Valentina, Solowij, Nadia and Yücel, Murat. (2016). The role of cannabinoids in neuroanatomic alterations in cannabis users. Biological Psychiatry. 79(7), pp. e17 - e31. https://doi.org/10.1016/j.biopsych.2015.11.013
Hippocampal harms, protection and recovery following regular cannabis use
Yücel, Murat, Lorenzetti, Valentina, Suo, C., Zalesky, Andrew, Fornito, Alex, Takagi, Michael J., Lubman, Dan I. and Solowij, Nadia. (2016). Hippocampal harms, protection and recovery following regular cannabis use. Translational Psychiatry. 6(1), pp. 1 - 7. https://doi.org/10.1038/tp.2015.201
An MRI study of white matter tract integrity in regular cannabis users: Effects of cannabis use and age
Jakabek, David, Yucel, Murat, Lorenzetti, Valentina and Solowij, Nadia. (2016). An MRI study of white matter tract integrity in regular cannabis users: Effects of cannabis use and age. Psychopharmacology. 233(19-20), pp. 3627 - 3637. https://doi.org/10.1007/s00213-016-4398-3
Gross morphological brain changes with chronic, heavy cannabis use
Lorenzetti, Valentina, Solowij, Nadia, Whittle, Sarah, Fornito, Alex, Lubman, Dan I., Pantelis, Christos and Yücel, Murat. (2015). Gross morphological brain changes with chronic, heavy cannabis use. British Journal of Psychiatry. 206(1), pp. 77 - 78. https://doi.org/10.1192/bjp.bp.114.151407
Cortico-limbic network abnormalities in individuals with current and past major depressive disorder
Klauser, Paul, Fornito, Alex, Lorenzetti, Valentina, Davey, Christopher G., Dwyer, Dominic B., Allen, Nicholas B. and Yücel, Murat. (2015). Cortico-limbic network abnormalities in individuals with current and past major depressive disorder. Journal of Affective Disorders. 173, pp. 45 - 52. https://doi.org/10.1016/j.jad.2014.10.041
LSD enhances the emotional response to music
Kaelen, M., Barrett, F. S., Roseman, L., Lorenz, R., Family, N., Bolstridge, M., Curran, Helen V., Feilding, A., Nutt, David J. and Carhart-Harris, R. L.. (2015). LSD enhances the emotional response to music. Psychopharmacology. 232(19), pp. 3607 - 3614. https://doi.org/10.1007/s00213-015-4014-y
The association between regular cannabis exposure and alterations of human brain morphology: An updated review of the literature
Lorenzetti, Valentina, Solowij, Nadia, Fornito, Alex, Lubman, Dan Ian and Yücel, Murat. (2014). The association between regular cannabis exposure and alterations of human brain morphology: An updated review of the literature. Current Pharmaceutical Design. 20(13), pp. 2138 - 2167. https://doi.org/10.2174/13816128113199990435
Effects of immediate-release opioid on memory functioning: A randomized-controlled study in patients receiving sustained-release opioids
Kamboj, S. K., Conroy, L., Tookman, A., Carroll, E., Jones, L. and Curran, H.. (2014). Effects of immediate-release opioid on memory functioning: A randomized-controlled study in patients receiving sustained-release opioids. European Journal of Pain. 18(10), pp. 1376 - 1384. https://doi.org/10.1002/j.1532-2149.2014.498.x
Effects of ecstasy on cooperative behaviour and perception of trustworthiness: A naturalistic study
Stewart, L. H., Ferguson, B., Morgan, C. J. A., Swaboda, N., Jones, L., Fenton, R., Wall, M. B. and Curran, H.. (2014). Effects of ecstasy on cooperative behaviour and perception of trustworthiness: A naturalistic study. Journal of Psychopharmacology. 28(11), pp. 1001 - 1008. https://doi.org/10.1177/0269881114544775
The neural cascade of olfactory processing: A combined fMRI-EEG study
Masaoka, Yuri, Harding, Ian H., Koiwa, Nobuyoshi, Yoshida, Masaki, Harrison, Ben J., Lorenzetti, Valentina, Ida, Masahiro, Izumizaki, Masahiko, Pantelis, Christos and Homma, Ikuo. (2014). The neural cascade of olfactory processing: A combined fMRI-EEG study. Respiratory Physiology & Neurobiology. 204, pp. 71 - 77. https://doi.org/10.1016/j.resp.2014.06.008
Prospective memory impairment in long-term opiate users
Terrett, Gillian, McLennan, Skye, Henry, Julie, Biernacki, Kathryn, Mercuri, Kimberly, Curran, Valerie and Rendell, Peter. (2014). Prospective memory impairment in long-term opiate users. Psychopharmacology. 231(13), pp. 2623 - 2632. https://doi.org/10.1007/s00213-014-3432-6
Benzodiazepines: Risks and benefits. A reconsideration
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