Cost-effectiveness of romosozumab for the treatment of postmenopausal women with severe osteoporosis at high risk of fracture in Sweden

Journal article

Söreskog, E., Lindberg, I., Kanis, J. A., Åkesson, K. E., Willems, D., Lorentzon, M., Ström, O., Berling, P. and Borgström, F.. (2021). Cost-effectiveness of romosozumab for the treatment of postmenopausal women with severe osteoporosis at high risk of fracture in Sweden. Osteoporosis International. 32, pp. 585-594. https://doi.org/10.1007/s00198-020-05780-8
AuthorsSöreskog, E., Lindberg, I., Kanis, J. A., Åkesson, K. E., Willems, D., Lorentzon, M., Ström, O., Berling, P. and Borgström, F.
Abstract

Summary
Romosozumab is a novel bone-building drug that reduces fracture risk. This health economic analysis indicates that sequential romosozumab-to-alendronate can be a cost-effective treatment option for postmenopausal women with severe osteoporosis at high risk of fracture.

Purpose
To estimate the cost-effectiveness of sequential treatment with romosozumab followed by alendronate (“romosozumab-to-alendronate”) compared with alendronate alone in patients with severe osteoporosis at high risk of fracture in Sweden.

Methods
A microsimulation model with a Markov structure was used to simulate fractures, costs, and quality-adjusted life years (QALYs), for women treated with romosozumab-to-alendronate or alendronate alone. Patients aged 74 years with a recent major osteoporotic fracture (MOF) were followed from the start of treatment until the age of 100 years or death. Treatment with romosozumab for 12 months was followed by alendronate for up to 48 months or alendronate alone with a maximum treatment duration of 60 months. The analysis had a societal perspective. Efficacy of romosozumab and alendronate were derived from phase III randomized controlled trials. Resource use and unit costs were collected from the literature. Cost-effectiveness was estimated using incremental cost-effectiveness ratio (ICER) with QALYs as effectiveness measures.

Results
The base case analysis showed that sequential romosozumab-to-alendronate treatment was associated with 0.089 additional QALYs at an additional cost of €3002 compared to alendronate alone, resulting in an ICER of €33,732. At a Swedish reference willingness-to-pay per QALY of €60,000, romosozumab-to-alendronate had a 97.9% probability of being cost-effective against alendronate alone. The results were most sensitive to time horizon, persistence assumptions, patient age, and treatment efficacy.

Conclusion
The results of this study indicate that sequential romosozumab-to-alendronate can be a cost-effective treatment option for postmenopausal women with severe osteoporosis at high risk of fracture.

Keywordscost-effectiveness; economic evaluation; imminent fracture risk; Markov-microsimulation model; osteoporosis; recent fracture
Year2021
JournalOsteoporosis International
Journal citation32, pp. 585-594
PublisherSpringer UK
ISSN0937-941X
Digital Object Identifier (DOI)https://doi.org/10.1007/s00198-020-05780-8
Scopus EID2-s2.0-85099022435
Research or scholarlyResearch
Page range585-594
Publisher's version
License
All rights reserved
File Access Level
Controlled
Output statusPublished
Publication dates
Online06 Jan 2021
Publication process dates
Accepted04 Dec 2020
Deposited30 Jun 2021
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Dimai, Hans P., Johansson, Helena, Harvey, Nicholas C., Lorentzon, Mattias, Liu, Enwu, Vandenput, Liesbeth, Fahrleitner-Pammer, Astrid, Pietschmann, Peter, Muschitz, Christian, McCloskey, Eugene V. and Kanis, John A.. (2022). Osteoporosis treatment in Austria—assessment of FRAX‑based intervention thresholds for high and very high fracture risk. Archives of Osteoporosis. 17, p. Article 141. https://doi.org/10.1007/s11657-022-01175-w
Greater pQCT calf muscle density is associated with lower fracture risk, independent of FRAX, falls and BMD : A meta-analysis in the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Orwoll, Eric, Cauley, Jane A., Kwok, Timothy, Karlsson, Magnus K., Rosengren, Björn, Ribom, Eva, Cawthon, Peggy M., Ensrud, Kristine, Liu, Enwu, Laskou, Faidra, Ward, Kate A., Dennison, Elaine M., Cooper, Cyrus, Kanis, John A., Vandenput, Liesbeth, Lorentzon, Mattias, Ohlsson, Claes, Mellström, Dan, ... McCloskey, Eugene. (2022). Greater pQCT calf muscle density is associated with lower fracture risk, independent of FRAX, falls and BMD : A meta-analysis in the Osteoporotic Fractures in Men (MrOS) Study. JBMR Plus. 6(12), p. e10696. https://doi.org/10.1002/jbm4.10696
The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study
Bokrantz, Tove, Manhem, Karin, Lorentzon, Mattias, Karlsson, Magnus, Ljunggren, Östen, Ohlsson, Claes and Mellström, Dan. (2022). The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study. Osteoporosis International. 33, pp. 2607-2617. https://doi.org/10.1007/s00198-022-06535-3
Effect of Discordant Hip Bone Density on Incident Fracture Risk : A Registry-Based Cohort Study
Leslie, William, Morin, Suzanne, Lix, Lisa, McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas and Kanis, John Anthony. (2022). Effect of Discordant Hip Bone Density on Incident Fracture Risk : A Registry-Based Cohort Study. Journal of Bone and Mineral Research. 37(10), pp. 2018-2024. https://doi.org/10.1002/jbmr.4672
An updated hip fracture incidence rate for Brazil : the Brazilian Validation Osteoporosis Study (BRAVOS)
Albergaria, Ben-Hur, Zerbini, Cristiano, Szejnfeld, Vera, Ragi Eis, Sergio, Silva, Dalisbor, da Cunha, Maria, McClung, Michael Roy, Kanis, John Anthony, McCloskey, Eugene, Vilaca, Tatiane and Lazaretti-Castro, Marise. (2022). An updated hip fracture incidence rate for Brazil : the Brazilian Validation Osteoporosis Study (BRAVOS). Archives of Osteoporosis. 17, pp. 1-9. https://doi.org/10.1007/s11657-022-01127-4
Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures
Kanis, John Anthony, Johansson, Helena, Harvey, Nicholas, Gudnason, Vilmundur, Sigurdsson, Gunnar, Siggeirsdottir, Kristin, Lorentzon, Karl Mattias, Liu, Enwu, Vandenput, Liesbeth and McCloskey, Eugene. (2022). Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures. Osteoporosis International. 33, pp. 2507-2515. https://doi.org/10.1007/s00198-022-06550-4
Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men : the MrOS Sweden cohort
Kristjansdottir, Hallgerdur, Mellstrom, Dan, Johansson, Peter, Karlsson, Magnus, Vandenput, Liesbeth, Lorentzon, Karl Mattias, Herlitz, Hans, Ohlsson, Claes, Lerner, Ulf and Lewerin, Catharina. (2022). Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men : the MrOS Sweden cohort. Archives of Osteoporosis. 17(1), pp. 1-9. https://doi.org/10.1007/s11657-022-01130-9
Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability — Results from the Women’s Health Initiative hormone therapy trials
Lorentzon, Mattias, Johansson, Helena, Harvey, Nicholas C., Liu, Enwu, Vandenput, Liesbeth, Crandall, Carolyn J., Cauley, Jane A., LeBoff, Meryl S., McCloskey, Eugene V. and Kanis, John A.. (2022). Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability — Results from the Women’s Health Initiative hormone therapy trials. Osteoporosis International. 33(11), pp. 2297-2305. https://doi.org/10.1007/s00198-022-06483-y
A micro-costing analysis of post-fracture care pathways : Results from the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)
Talevski, J, Sanders, K. M., Lal, A., Watts, J. J., Beauchamp, A., Duque, G., Borgström, F., Kanis, J. A., Svedbom, A. and Brennan-Olsen, S. L.. (2022). A micro-costing analysis of post-fracture care pathways : Results from the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS). Osteoporosis International. 33, pp. 1895-1907. https://doi.org/10.1007/s00198-022-06460-5
Bone turnover marker profiling and fracture risk in older women : Fracture risk from age 75 to 90
Ivaska, Kaisa K., McGuigan, Fiona E., Malmgren, Linnea, Gerdhem, Paul, Johansson, Helena, Kanis, John A. and Åkesson, Kristina E.. (2022). Bone turnover marker profiling and fracture risk in older women : Fracture risk from age 75 to 90. Calcified Tissue International. 111(3), pp. 288-299. https://doi.org/10.1007/s00223-022-00996-8
Assessment and management of imminent fracture risk in the setting of the fracture liaison service [Editorial]
Javaid, M. K., Harvey, N. C., McCloskey, E. V., Kanis, J. A. and Cooper, C.. (2022). Assessment and management of imminent fracture risk in the setting of the fracture liaison service [Editorial] Springer. https://doi.org/10.1007/s00198-021-06284-9
Management of patients at very high risk of osteoporotic fractures through sequential treatments
Curtis, Elizabeth M., Reginster, Jean-Yves, Al-Daghri, Nasser, Biver, Emmanuel, Brandi, Maria Luisa, Cavalier, Etienne, Hadji, Peymann, Halbout, Philippe, Harvey, Nicholas C., Hiligsmann, Mickaël, Javaid, M. Kassim, Kanis, John A., Kaufman, Jean-Marc, Lamy, Olivier, Matijevic, Radmila, Perez, Adolfo Diez, Radermecker, Régis Pierre, Rosa, Mário Miguel, Thomas, Thierry, ... Cooper, Cyrus. (2022). Management of patients at very high risk of osteoporotic fractures through sequential treatments. Aging Clinical and Experimental Research. 34(4), pp. 695-714. https://doi.org/10.1007/s40520-022-02100-4
Trabecular bone score adjustment for the Fracture Risk Assessment tool (FRAX®) [Letter]
McCloskey, Eugene, Harvey, Nicholas C., Lorentzon, Mattias, Johansson, Helena and Kanis, John A.. (2022). Trabecular bone score adjustment for the Fracture Risk Assessment tool (FRAX®) [Letter]. Calcified Tissue International. 111(2), pp. 226-227. https://doi.org/10.1007/s00223-022-00994-w
Osteoporosis epidemiology using international cohorts
Lorentzon, Mattias and Abrahamsen, Bo. (2022). Osteoporosis epidemiology using international cohorts. Current Opinion in Rheumatology. 34(5), pp. 280-288. https://doi.org/10.1097/BOR.0000000000000885
Interdisciplinary management of FGF23-related phosphate wasting syndromes : A Consensus Statement on the evaluation, diagnosis and care of patients with -linked hypophosphataemia
Trombetti, Andrea, Al-Daghri, Nasser, Brandi, Maria Luisa, Cannata-Andia, Jorge B., Cavalier, Etienne, Chandran, Manju, Chaussain, Catherine, Cipullo, Lucia, Cooper, Cyrus, Haffner, Dieter, Harvengt, Pol, Harvey, Nicholas C., Javaid, Muhammad Kassim, Jiwa, Famida, Kanis, John A., Laslop, Andrea, Laurent, Michaël R., Linglart, Agnès, Marques, Andréa, ... Rizzoli, René. (2022). Interdisciplinary management of FGF23-related phosphate wasting syndromes : A Consensus Statement on the evaluation, diagnosis and care of patients with -linked hypophosphataemia. Nature Reviews Endocrinology. 18(6), pp. 366-384. https://doi.org/10.1038/s41574-022-00662-x
FRAX
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Lorentzon, Mattias, Liu, Enwu, Leslie, William D. and McCloskey, Eugene V.. (2022). FRAX. In In Pape, Hans-Christoph, Kates, Stephen L., Hierholzer, Christian and Bischoff-Ferrari, Heike A. (Ed.). Senior trauma patients : An integrated approach pp. 89-99 Springer. https://doi.org/10.1007/978-3-030-91483-7_10
Epidemiology and economic burden of osteoporosis in Greece
Makras, P., Lyritis, G. P., Rizou, S., Drakopoulou, T., Trovas, G., Willers, C., Norton, N., Harvey, N. C., Jacobson, T., Johansson, H., Lorentzon, M., McCloskey, E. V., Borgström, F. and Kanis, J. A.. (2022). Epidemiology and economic burden of osteoporosis in Greece. Archives of Osteoporosis. 17, p. Article 23. https://doi.org/10.1007/s11657-021-00969-8
The global approach to rehabilitation following an osteoporotic fragility fracture : A review of the rehabilitation working group of the International Osteoporosis Foundation (IOF) committee of scientific advisors
Pinto, D., Alshahrani, M., Chapurlat, R., Chevalley, T., Dennison, E., Camargos, B. M., Papaioannou, A., Silverman, S., Kaux, J.-F., Lane, N. E., Morales Torres, J., Paccou, J., Rizzoli, R., Bruyère, O., on behalf of the Rehabilitation Working Group of IOF Committee of Scientific Advisors and Kanis, J. A.. (2022). The global approach to rehabilitation following an osteoporotic fragility fracture : A review of the rehabilitation working group of the International Osteoporosis Foundation (IOF) committee of scientific advisors. Osteoporosis International. 33(3), pp. 527-540. https://doi.org/10.1007/s00198-021-06240-7
Prediction of imminent fracture risk in Canadian women and men aged 45 years or older : External validation of the Fracture Risk Evaluation Model (FREM)
Möller, Sören, Skjødt, Michael K., Yan, Lin, Abrahamsen, Bo, Lix, Lisa M., McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C., Kanis, John A., Rubin, Katrine Hass and Leslie, William D.. (2022). Prediction of imminent fracture risk in Canadian women and men aged 45 years or older : External validation of the Fracture Risk Evaluation Model (FREM). Osteoporosis International. 33(1), pp. 57-66. https://doi.org/10.1007/s00198-021-06165-1
One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD
Larsson, B. A. M., Johansson, L., Mellström, D., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., McCloskey, E., Liu, E., Sundh, D, Kanis, J. A. and Lorentzon, M.. (2022). One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD. Osteoporosis International. 33(1), pp. 185-194. https://doi.org/10.1007/s00198-021-06039-6
Factors associated with changes involumetric bone mineral density andcortical area in men with ankylosing spondylitis : A 5‑year prospective studyusing HRpQCT.
Deminger, A., Klingberg, E., Lorentzon, M., Hedberg, M., Carlsten, H., Jacobsson, L.T.H. and Forsblad-d'Elia, H.. (2022). Factors associated with changes involumetric bone mineral density andcortical area in men with ankylosing spondylitis : A 5‑year prospective studyusing HRpQCT. Osteoporosis International. 33(1), pp. 205-216. https://doi.org/10.1007/s00198-021-06049-4
Prevalence of physical frailty : Results from the DO-HEALTH Study
Gagesch, Michael, Chocano-Bedoya, P. O., Abderhalden, L. A., Freystaetter, G., Sadlon, A., Kanis, J. A., Kressig, R. W., Guyonnet, S., DaSilva, J. A. P., Felsenberg, D., Rizzoli, R., Blauth, M., Orav, E. J., Egli, A. and Bischoff-Ferrari, H. A.. (2022). Prevalence of physical frailty : Results from the DO-HEALTH Study. The Journal of Frailty and Aging. 11(1), pp. 18-25. https://doi.org/10.14283/jfa.2021.18
Sex differences in recovery of quality of life 12 months post-fracture in community-dwelling older adults : Analyses of the Australian arm of the International Costs and Utilities Related to Osteoporotic Fractures Study (AusICUROS)
Talevski, J, Sanders, K. M., Watts, J. J., Nicholson, G. C., Seeman, E., Iuliano, S., Prince, R., March, L., Winzenberg, T., Duque, G., Ebeling, P. R., Borgström, F., Kanis, J. A., Stuart, A. L., Beauchamp, A. and Brennan-Olsen, S. L.. (2022). Sex differences in recovery of quality of life 12 months post-fracture in community-dwelling older adults : Analyses of the Australian arm of the International Costs and Utilities Related to Osteoporotic Fractures Study (AusICUROS). Osteoporosis International. 33(1), pp. 67-75. https://doi.org/10.1007/s00198-021-06058-3
Designing an Iran FRAX model and defining intervention and assessment thresholds for osteoporosis
Khashayar, P., Keshtkar, A., Ostovar, A., Larijani, B., Johansson, H., Harvey, N, Lorentzon, M., McCloskey, U. and Kanis, J.. (2021). Designing an Iran FRAX model and defining intervention and assessment thresholds for osteoporosis. Iranian Journal of Epidemiology. 16(4), pp. 296-304.
Fracture risk assessment and how to implement a fracture liaison service
Fuggle, Nicholas R., Javaid, M. Kassim, Fujita, Masaki, Halbout, Philippe, Dawson-Hughes, Bess, Rizzoli, Rene, Reginster, Jean-Yves, Kanis, John A. and Cooper, Cyrus. (2021). Fracture risk assessment and how to implement a fracture liaison service. In In Falaschi, Paolo and Marsh, David (Ed.). Orthogeriatrics : The management of older patients with fragility fractures pp. 241-256 Springer Nature Switzerland AG. https://doi.org/10.1007/978-3-030-48126-1_14
Federal clinical guidelines for diagnosis, treatment and prevention of osteoporosis
Belaya, Zh E., Belova, K. Yu., Biryukova, E. V., Dedov, I. I., Dzeranova, L. K., Drapkina, O. M., Dreval, A. V., Dubovitskaya, T. A., Dudinskaya, E. N., Ershova, O. B., Zagorodniy, N. V., Ilyukhina, O. B., Kanis, J. A., Kryukova, I. V., Lesnyak, O. M., Mamedova, E. O., Marchenkova, L. A., Mel'nichenko, G. A., Nikankina, L. V., ... Yakushevskaya, O. V.. (2021). Federal clinical guidelines for diagnosis, treatment and prevention of osteoporosis. Osteoporosis and Bone Diseases. 24(2), pp. 4-47. https://doi.org/10.14341/osteo12930
Fracture risk assessment by the FRAX model
McCloskey, E. V., Harvey, N. C., Johansson, H., Lorentzon, M., Liu, E., Vandenput, L., Leslie, W. D. and Kanis, J. A.. (2021). Fracture risk assessment by the FRAX model. Climacteric. 25(1), pp. 22-28. https://doi.org/10.1080/13697137.2021.1945027
Short time horizons for fracture prediction tools : Time for a rethink
McCloskey, E. V., Borgstrom, F., Cooper, C., Harvey, N. C., Javaid, M. K., Lorentzon, M. and Kanis, J. A.. (2021). Short time horizons for fracture prediction tools : Time for a rethink. Osteoporosis International. 32(6), pp. 1019-1025. https://doi.org/10.1007/s00198-021-05962-y
The application of FRAX in Saudi Arabia
Al-Daghri, Nasser M., Sabico, Shaun, Al-Saleh, Yousef, Sulimani, Riad, Aljohani, Naji J., Sheshah, Eman, Alodhayani, Abdulaziz, Harvey, Nicholas C., Liu, Enwu, Lorentzon, Mattias, McCloskey, Eugene V., Vandenput, Liesbeth, Johansson, Helena and Kanis, John A.. (2021). The application of FRAX in Saudi Arabia. Archives of Osteoporosis. 16(1), p. Article 166. https://doi.org/10.1007/s11657-021-01024-2
Costs of patient management over 18 months following a hip, clinical vertebral, distal forearm, or proximal humerus fragility fracture in France—results from the ICUROS study
Coassy, Astrid, Svedbom, Axel, Locrelle, Hervé, Chapurlat, Roland, Cortet, Bernard, Fardellone, Patrice, Orcel, Philippe, Roux, Christian, Borgström, Fredrik, Kanis, John A. and Thomas, Thierry. (2021). Costs of patient management over 18 months following a hip, clinical vertebral, distal forearm, or proximal humerus fragility fracture in France—results from the ICUROS study. Osteoporosis International. 33(3), p. 625–635. https://doi.org/10.1007/s00198-021-06189-7
Fractures and fall injuries after hospitalization for seasonal influenza—a national retrospective cohort study
Axelsson, K. F., Litsne, H. and Lorentzon, M.. (2021). Fractures and fall injuries after hospitalization for seasonal influenza—a national retrospective cohort study. Osteoporosis International. 33(1), pp. 47-56. https://doi.org/10.1007/s00198-021-06068-1
FRAX-based intervention thresholds for Pakistan
Johansson, H., Naureen, G., Iqbal, R., Jafri, L., Khan, A. H., Umer, M., Liu, E., Vandenput, L., Lorentzon, M., McCloskey, E. V., Kanis, J. A. and Harvey, N. C.. (2021). FRAX-based intervention thresholds for Pakistan. Osteoporosis International. 33(1), pp. 105-112. https://doi.org/10.1007/s00198-021-06087-y
Serum glycine levels are associated with cortical bone properties and fractures risk in men
Eriksson, Anna L., Friedrich, Nele, Karlsson, Magnus K., Ljunggren, Osten, Lorentzon, Mattias, Nethander, Maria, Wallaschofski, Henri, Mellstrom, Dan and Ohlsson, Claes. (2021). Serum glycine levels are associated with cortical bone properties and fractures risk in men. The Journal of Clinical Endocrinology and Metabolism. 106(12), pp. e5021-e5029. https://doi.org/10.1210/clinem/dgab544
SCOPE 2021 : A new scorecard for osteoporosis in Europe
Kanis, John A., Norton, Nicholas, Harvey, Nicholas C., Jacobson, Trolle, Johansson, Helena, Lorentzon, Mattias, McCloskey, Eugene V., Willers, Carl and Borgström, Fredrik. (2021). SCOPE 2021 : A new scorecard for osteoporosis in Europe. Archives of Osteoporosis. 16(1), p. Article 82. https://doi.org/10.1007/s11657-020-00871-9
Sarcopenia definitions as predictors of fracture risk independent of FRAX®, falls, and BMD in the Osteoporotic Fractures in Men (MrOS) Study : A meta-analysis
Harvey, Nicholas C., Orwoll, Eric, Kwok, Timothy, Karlsson, Magnus K., Rosengren, Björn E., Ribom, Eva, Cauley, Jane A., Cawthon, Peggy M., Ensrud, Kristine, Liu, Enwu, Cruz-Jentoft, Alfonso J., Fielding, Roger A., Cooper, Cyrus, Kanis, John A., Lorentzon, Mattias, Ohlsson, Claes, Mellström, Dan, Johansson, Helena and McCloskey, Eugene. (2021). Sarcopenia definitions as predictors of fracture risk independent of FRAX®, falls, and BMD in the Osteoporotic Fractures in Men (MrOS) Study : A meta-analysis. Journal of Bone and Mineral Research. 36(7), pp. 1235-1244. https://doi.org/10.1002/jbmr.4293
Ukranian FRAX version in the male osteoporosis management
Povoroznyuk, V, Johansson, Helena, Grygorieva, N, Kanis, John Anthony, Musiienko, A, Lorentzon, Karl Mattias, Harvey, N, McCloskey, E and Liu, Enwu. (2021). Ukranian FRAX version in the male osteoporosis management. Bol', Sustavy, Pozvonochnik (Pain, Joints, Spine). 11(2), pp. 53-61. https://doi.org/10.22141/2224-1507.11.2.2021.236563
Physical exercise is associated with beneficial bone mineral density and body composition in young adults with childhood-onset inflammatory bowel disease
Sigurdsson, Gudmundur Vignir, Schmidt, Susanne, Mellström, Dan, Ohlsson, Claes, Karlsson, Magnus, Lorentzon, Mattias and Saalman, Robert. (2021). Physical exercise is associated with beneficial bone mineral density and body composition in young adults with childhood-onset inflammatory bowel disease. Scandinavian Journal of Gastroenterology. 56(6), pp. 699-707. https://doi.org/10.1080/00365521.2021.1913759
RSPO3 is important for trabecular bone and fracture risk in mice and humans
Nilsson, Karin H., Henning, Petra, El Shahawy, Maha, Nethander, Maria, Andersen, Thomas, Ejersted, Charlotte, Wu, Jianyao, Gustafsson, Karin, Koskela, Antti, Tuukkanen, Juha, Souza, Pedro, Tuckermann, Jan, Lorentzon, Karl Mattias, Ruud, Linda, Lehtimaki, Terho, Tobias, Jon, Zhou, Sirui, Lerner, Ulf H., Richards, J. Brent, ... Ohlsson, Claes. (2021). RSPO3 is important for trabecular bone and fracture risk in mice and humans. Nature Communications. 12(1), p. Article: 4923. https://doi.org/10.1038/s41467-021-25124-2
Impact of population-based or targeted BMD interventions on fracture incidence
Harvey, N. C., Kanis, J. A., Liu, E., Vandenput, L., Lorentzon, M., Cooper, C, McCloskey, E. and Johansson, H.. (2021). Impact of population-based or targeted BMD interventions on fracture incidence. Osteoporosis International. 32(10), pp. 1973-1979. https://doi.org/10.1007/s00198-021-05917-3
Subclinical hyperthyroidism is associated with increased risk of vertebral fractures in older men
Svensson, J., Ohlsson, C., Karlsson, M. K., Lorentzon, M., Lewerin, C. and Mellstrom, D.. (2021). Subclinical hyperthyroidism is associated with increased risk of vertebral fractures in older men. Osteoporosis International. 32, pp. 2257-2265. https://doi.org/10.1007/s00198-021-05964-w
FRAX-based intervention thresholds in eight Eurasian countries : Armenia, Belarus, Georgia, Kazakhstan, the Kygyz Republic, Moldova, the Russian Federation, and Uzbekistan
Lesnyak, Olga, Zakroyeva, Alla, Babalyan, Varta, Cazac, Victor, Gabdulina, Gulzhan, Ismailov, Said, Lobanchenko, Olga, Rudenka, Ema, Tsagareli, Marina, Johansson, Helena, Harvey, Nickolas C., McCloskey, Eugene and Kanis, John A.. (2021). FRAX-based intervention thresholds in eight Eurasian countries : Armenia, Belarus, Georgia, Kazakhstan, the Kygyz Republic, Moldova, the Russian Federation, and Uzbekistan. Archives of Osteoporosis. 16, p. Article 87. https://doi.org/10.1007/s11657-021-00962-1
FRAX-based intervention thresholds for osteoporosis treatment in Ukraine
Povoroznyuk, Vladyslav, Grygorieva, Nataliia, Johansson, Helena, Lorentzon, Mattias, Harvey, Nicholas C., McCloskey, Eugene V., Musienko, Anna, Liu, Enwu, Kanis, John A., Zaverukha, Nataliia and Ivanyk, Oksana. (2021). FRAX-based intervention thresholds for osteoporosis treatment in Ukraine. Journal of Osteoporosis. 2021, p. Article 2043479. https://doi.org/10.1155/2021/2043479
An assessment of intervention thresholds for very high fracture risk applied to the NOGG guidelines : A report for the National Osteoporosis Guideline Group (NOGG)
Kanis, J. A., Johansson, H., Harvey, N. C., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2021). An assessment of intervention thresholds for very high fracture risk applied to the NOGG guidelines : A report for the National Osteoporosis Guideline Group (NOGG). Osteoporosis International. 32, pp. 1951-1960. https://doi.org/10.1007/s00198-021-05942-2
A novel economic framework to assess the cost-effectiveness of bone-forming agents in the prevention of fractures in patients with osteoporosis
Söreskog, E., Borgström, F., Lindberg, I., Ström, O., Willems, D., Libanati, C., Kanis, J. A., Stollenwerk, B. and Charokopou, M.. (2021). A novel economic framework to assess the cost-effectiveness of bone-forming agents in the prevention of fractures in patients with osteoporosis. Osteoporosis International. 32(7), pp. 1301-1311. https://doi.org/10.1007/s00198-020-05765-7
A country-specific FRAX model for Botswana
Kebaetse, M., Nkhwa, S., Mogodi, M., Masunge, J., Gureja, Y. P., Ramabu, M., Mmopelwa, T., Sharif, I., Orford, A., Harvey, N. C., McCloskey, E. V., Cauley, J. A., Kanis, J. A. and Johansson, H.. (2021). A country-specific FRAX model for Botswana. Archives of Osteoporosis. 16, p. Article 90. https://doi.org/10.1007/s11657-021-00965-y
Recovery of quality of life is associated with lower mortality 5-year post-fracture : the Australian arm of the International Costs and Utilities Related to Osteoporotic Fractures Study (AusICUROS)
Talevski, Jason, Sanders, Kerrie M., Vogrin, Sara, Duque, Gustavo, Beauchamp, Alison, Seeman, Ego, Iuliano, Sandra, Svedbom, Axel, Borgström, Fredrik, Kanis, John A., Stuart, Amanda L. and Brennan-Olsen, Sharon L.. (2021). Recovery of quality of life is associated with lower mortality 5-year post-fracture : the Australian arm of the International Costs and Utilities Related to Osteoporotic Fractures Study (AusICUROS). Archives of Osteoporosis. 16, p. Article 112. https://doi.org/10.1007/s11657-021-00981-y
The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk assessment
Gullberg, Joanna, Al-Okshi, Ayman, Homar Asan, Dalia, Zainea, Anita, Sundh, Daniel, Lorentzon, Mattias and Lindh, Christina. (2021). The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk assessment. Dentomaxillofacial Radiology. 50, p. Article 20210175. https://doi.org/10.1259/dmfr.20210175
Calibration of FRAX : A journey, not a destination [Editorial]
Leslie, William D. and Kanis, John A.. (2021). Calibration of FRAX : A journey, not a destination [Editorial]. Calcified Tissue International. 109, pp. 597-599. https://doi.org/10.1007/s00223-021-00891-8
A multicenter study to evaluate harmonization of assays for C-Terminal Telopeptides of Type I Collagen (ß-CTX) : A report from the IFCC-IOF Committee for Bone Metabolism (C-BM)
Cavalier, E., Eastell, R., Jørgensen, N. R., Makris, K., Tournis, S., Vasikaran, S., Kanis, J. A., Cooper, C., Pottel, H. and Morris, H. A.. (2021). A multicenter study to evaluate harmonization of assays for C-Terminal Telopeptides of Type I Collagen (ß-CTX) : A report from the IFCC-IOF Committee for Bone Metabolism (C-BM). Calcified Tissue International. 108(6), pp. 785-797. https://doi.org/10.1007/s00223-021-00816-5
Clodronate
McCloskey, Eugene, Paterson, Alexander H., Powles, Trevor and Kanis, John A.. (2021). Clodronate. Bone. 143, p. 115715. https://doi.org/10.1016/j.bone.2020.115715
The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2021). The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture. Osteoporosis International. 32(8), pp. 1547-1555. https://doi.org/10.1007/s00198-020-05803-4
Metabolic alterations in older women with low bone mineral density supplemented with lactobacillus reuteri
Li, Peishun, Sundh, Daniel, Ji, Boyang, Lappa, Dimitra, Ye, Lingqun, Nielsen, Jens and Lorentzon, Mattias. (2021). Metabolic alterations in older women with low bone mineral density supplemented with lactobacillus reuteri. JBMR Plus. 5(4), p. e10478. https://doi.org/10.1002/jbm4.10478
Predictive value of DXA appendicular lean mass for incident fractures, falls, and mortality, independent of prior falls, FRAX, and BMD : Findings from the Women's Health Initiative (WHI)
Harvey, Nicholas C., Kanis, John A., Liu, Enwu, Cooper, Cyrus, Lorentzon, Mattias, Bea, Jennifer W., Carbone, Laura, Cespedes Feliciano, Elizabeth M., Laddu, Deepika R., Schnatz, Peter F., Shadyab, Aladdin H., Stefanick, Marcia L., Wactawski-Wende, Jean, Crandall, Carolyn J., Johansson, Helena and McCloskey, Eugene. (2021). Predictive value of DXA appendicular lean mass for incident fractures, falls, and mortality, independent of prior falls, FRAX, and BMD : Findings from the Women's Health Initiative (WHI). Journal of Bone and Mineral Research. 36(4), pp. 654-661. https://doi.org/10.1002/jbmr.4239
High platelet count is associated with low bone mineral density : The MrOS Sweden cohort
Kristjansdottir, H. L., Mellström, D., Johansson, P., Karlsson, M., Vandenput, L., Lorentzon, M., Herlitz, H., Ohlsson, C., Lerner, U. H. and Lewerin, C.. (2021). High platelet count is associated with low bone mineral density : The MrOS Sweden cohort. Osteoporosis International. 32, pp. 865-871. https://doi.org/10.1007/s00198-020-05766-6
Romosozumab efficacy on fracture outcomes is greater in patients at high baseline fracture risk : A post hoc analysis of the first year of the frame study
McCloskey, E. V., Johansson, H., Harvey, N. C., Lorentzon, K., Shi, Y. and Kanis, J. A.. (2021). Romosozumab efficacy on fracture outcomes is greater in patients at high baseline fracture risk : A post hoc analysis of the first year of the frame study. Osteoporosis International. 32(8), pp. 1601-1608. https://doi.org/10.1007/s00198-020-05815-0
Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis
Drevinge, Christina, Scheffler, Julia M., Koro-Arvidsson, Catalin, Sundh, Daniel, Carlsten, Hans, Gjertsson, Inger, Lindholm, Catharina, Lorentzon, Mattias, Rudin, Anna, Ekwall, Anna-Karin Hultgård and Islander, Ulrika. (2021). Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis. PLoS ONE. 16(3), p. e0249205. https://doi.org/10.1371/journal.pone.0249205
FRAX-based fracture probabilities in South Africa
Johansson, Helena, Dela, Sapna S., Cassim, Bilkish, Paruk, Farhanah, Brown, Susan L., Conradie, Magda, Harvey, Nicholas C., Jordaan, Johannes D., Kalla, Asgar A., Liu, Enwu, Lorentzon, Mattias, Lukhele, Mkhululi, McCloskey, Eugene V., Mohamed, Ozayr, Chutterpaul, Pariva, Vandenput, Liesbeth and Kanis, John A.. (2021). FRAX-based fracture probabilities in South Africa. Archives of Osteoporosis. 16(1), p. 51. https://doi.org/10.1007/s11657-021-00905-w
Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
Lu, Tianyuan, Forgetta, Vincenzo, Keller-Baruch, Julyan, Nethander, Maria, Bennett, Derrick, Forest, Marie, Bhatnagar, Sahir, Walters, Robin G., Lin, Kuang, Chen, Zhengming, Li, Liming, Karlsson, Magnus, Mellström, Dan, Orwoll, Eric, McCloskey, Eugene V., Kanis, John A., Leslie, William D., Clarke, Robert J., Ohlsson, Claes, ... Richards, J. Brent. (2021). Improved prediction of fracture risk leveraging a genome-wide polygenic risk score. Genome Medicine. 13, p. 16. https://doi.org/10.1186/s13073-021-00838-6
Health service use pathways associated with recovery of quality of life at 12-months for individual fracture sites : Analyses of the International Costs and Utilities Related to Osteoporotic fractures Study (ICUROS)
Talevski, Jason, Sanders, Kerrie M., Busija, Ljoudmila, Beauchamp, Alison, Duque, Gustavo, Borgström, Fredrik, Kanis, John A., Svedbom, Axel, Stuart, Amanda L. and Brennan-Olsen, Sharon. (2021). Health service use pathways associated with recovery of quality of life at 12-months for individual fracture sites : Analyses of the International Costs and Utilities Related to Osteoporotic fractures Study (ICUROS). Bone. 114, p. 115805. https://doi.org/10.1016/j.bone.2020.115805
Health service use and quality of life recovery 12 months following major osteoporotic fracture : latent class analyses of the international costs and utilities related to osteoporotic fractures study (ICUROS)
Talevski, Jason, Sanders, Kerrie M., Busija, Ljoudmila, Beauchamp, Alison, Duque, Gustavo, Borgström, Fredrik, Kanis, John A., Svedbom, Axel, Connaughton, Catherine, Stuart, Amanda L. and Brennan-Olsen, Sharon L.. (2021). Health service use and quality of life recovery 12 months following major osteoporotic fracture : latent class analyses of the international costs and utilities related to osteoporotic fractures study (ICUROS). Journal of Bone and Mineral Research. 36(2), pp. 252-261. https://doi.org/10.1002/jbmr.4181
Epidemiology of hip fracture in Botswana
Kebaetse, M., Nkhwa, S., Mogodi, M., Masunge, J., Gureja, Y. P., Ramabu, M., Mmopelwa, T., Sharif, I., Orford, A., Johansson, H., Harvey, N. C., McCloskey, E. V., Cauley, J. A. and Kanis, J. A.. (2021). Epidemiology of hip fracture in Botswana. Archives of Osteoporosis. 16, p. 24. https://doi.org/10.1007/s11657-021-00885-x
Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood
Bhattoa, Harjit P., Cavalier, Etienne, Eastell, Richard, Heijboer, Annemieke C., Jørgensen, Niklas R., Makris, Konstantinos, Ulmer, Candice Z., Kanis, John A., Cooper, Cyrus, Silverman, Stuart L. and Vasikaran, Samuel D.. (2021). Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood. Clinica Chimica Acta. 515, pp. 16-20. https://doi.org/10.1016/j.cca.2020.12.023
A surrogate FRAX model for Pakistan
Naureen, G., Johansson, H., Iqbal, R., Jafri, L., Khan, A. H., Umer, M., Liu, E., Vandenput, L., Lorentzon, M., Harvey, N. C., McCloskey, E. V. and Kanis, J. A.. (2021). A surrogate FRAX model for Pakistan. Archives of Osteoporosis. 16, p. 34. https://doi.org/10.1007/s11657-021-00894-w
The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L., Leslie, W. D. and McCloskey, E. V.. (2021). The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture. Osteoporosis International. 32(1), pp. 47-54. https://doi.org/10.1007/s00198-020-05700-w
The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density
Larsson, B. A. M., Johansson, L., Johansson, H., Axelsson, K. F., Harvey, N., Vandenput, L., Magnusson, P., McCloskey, E., Liu, E., Kanis, J. A., Sundh, D. and Lorentzon, M.. (2021). The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density. Osteoporosis International. 32(1), pp. 75-84. https://doi.org/10.1007/s00198-020-05681-w
Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men : The MrOS Sweden study
Wallin, Maria, Barregard, Lars, Sallsten, Gerd, Lundh, Thomas, Sundh, Daniel, Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2021). Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men : The MrOS Sweden study. Bone. 143, p. 115768. https://doi.org/10.1016/j.bone.2020.115768
Fracture risk assessment in celiac disease : A registry-based cohort study
Duerksen, D. R., Lix, L. M., Johansson, H., McCloskey, E. V., Harvey, N. C., Kanis, J. A. and Leslie, W. D.. (2021). Fracture risk assessment in celiac disease : A registry-based cohort study. Osteoporosis International. 32(1), pp. 93-99. https://doi.org/10.1007/s00198-020-05579-7
Fracture prediction from FRAX for Canadian ethnic groups : A registry-based cohort study
Leslie, W. D., Morin, S. N., Lix, L. M., McCloskey, E. V., Johansson, H., Harvey, N. C. and Kanis, J. A.. (2021). Fracture prediction from FRAX for Canadian ethnic groups : A registry-based cohort study. Osteoporosis International. 32(1), pp. 113-122. https://doi.org/10.1007/s00198-020-05594-8
Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women
Kanis, J. A., Harvey, N. C., Lorentzon, M., Liu, E., Vandenput, L., McCloskey, E. V. and Johansson, H.. (2021). Combining fracture outcomes in phase 3 trials of osteoporosis : An analysis of the effects of denosumab in postmenopausal women. Osteoporosis International. 32(1), pp. 165-171. https://doi.org/10.1007/s00198-020-05699-0
DO-HEALTH : Vitamin D3 - Omega3 - Home exercise - Healthy aging and longevity trial - Design of a multinational clinical trial on healthy aging among European seniors
Bischoff-Ferrari, Heike A., de Godoi Rezende Costa Molino, Caroline, Rival, Sandrine, Vellas, Bruno, Rizzoli, René, Kressig, Reto W., Kanis, John A., Manson, JoAnn E., Dawson-Hughes, Bess, Orav, Endel J., da Silva, José A. P., Blauth, Michael, Felsenberg, Dieter, Ferrari, Stephen M., Theiler, Robert and Egli, Andreas. (2021). DO-HEALTH : Vitamin D3 - Omega3 - Home exercise - Healthy aging and longevity trial - Design of a multinational clinical trial on healthy aging among European seniors. Contemporary Clinical Trials. 100, p. 106124. https://doi.org/10.1016/j.cct.2020.106124
Measured height loss predicts incident clinical fractures independently from FRAX : A registry-based cohort study
Leslie, W. D., Schousboe, J. T., Morin, S. N., Martineau, P., Lix, L. M., Johansson, H., McCloskey, E. V., Harvey, N. C. and Kanis, J. A.. (2020). Measured height loss predicts incident clinical fractures independently from FRAX : A registry-based cohort study. Osteoporosis International. 31, pp. 1079-1087. https://doi.org/10.1007/s00198-020-05313-3
Summary of the draft federal clinical guidelines for osteoporosis
Belaya, Zhanna E., Rozhinskaya, Lyudmila Y., Grebennikova, Tatiana A., Kanis, J. A., Pigarova, Ekaterina A., Rodionova, Svetlana S., Toroptsova, Natalya V., Nikitinskaya, Oksana A., Skripnikova, Irina A., Drapkina, Oksana M., Ershova, Olga V., Biryukova, Elena V., Lesnyak, Olga M., Tsoriev, Timur T., Belova, Kseniya Y., Marchenkova, Larisa A., Dzeranova, Larisa K., Dreval, Aleksandr V., Mamedova, Elizaveta O., ... Dedov, Ivan I.. (2020). Summary of the draft federal clinical guidelines for osteoporosis. Osteoporosis and Bone Diseases. 23(2), pp. 4-21. https://doi.org/10.14341/osteo12373
Machine learning to predict osteoporotic fracture risk from genotypes
Forgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John, Morris, John A., Kanis, John A., Kiel, Douglas P., McCloskey, Eugene V., Rivadeneira, Fernando, Johannson, Helena, Harvey, Nicholas, Cooper, Cyrus, Evans, David M., Pineau, Joelle, Leslie, William D., Greenwood, Celia M. T. and Richards, J. Brent. (2020). Machine learning to predict osteoporotic fracture risk from genotypes. Cold Spring Harbor Protocols. pp. 1-22. https://doi.org/10.1101/413716
Screening for high hip fracture risk does not impact on falls risk : A post hoc analysis from the SCOOP study
Condurache, C. I., Chiu, S., Chotiyarnwong, P., Johansson, H., Shepstone, L., Lenaghan, E., Cooper, C., Clarke, S., Khioe, R. F. S., Fordham, R., Gittoes, N., Harvey, I., Harvey, N. C., Heawood, A., Holland, R., Howe, A., Kanis, J. A., Marshall, T., O’Neill, T. W., ... the SCOOP Study Team. (2020). Screening for high hip fracture risk does not impact on falls risk : A post hoc analysis from the SCOOP study. Osteoporosis International. 31(3), pp. 457-464. https://doi.org/10.1007/s00198-019-05270-6
Epidemiology of hip fracture and the development of a FRAX model for Uzbekistan
Lesnyak, O., Ismailov, S., Shakirova, M., Alikhanova, N., Zakroyeva, A., Abboskhujaeva, L., Johansson, H., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). Epidemiology of hip fracture and the development of a FRAX model for Uzbekistan. Archives of Osteoporosis. 15(1), p. 119. https://doi.org/10.1007/s11657-020-00792-7
Pharmacologic intervention for prevention of fractures in osteopenic and osteoporotic postmenopausal women : Systemic review and meta-analysis
Wu, Chih-Hsing, Hung, Wei-Chieh, Chang, Ing-Lin, Tsai, Tsung-Ting, Chang, Yin-Fan, McCloskey, Eugene V., Watts, Nelson B., McClung, Michael R., Huang, Chun-Feng, Chen, Chung-Hwan, Wu, Kun-Ling, Tsai, Keh-Sung, Chan, Ding-Cheng, Chen, Jung-Fu, Tu, Shih-Te, Hwang, Jawl-Shan, Xia, Weibo, Matsumoto, Toshio, Chung, Yoon-Sok, ... Chan, Wing P.. (2020). Pharmacologic intervention for prevention of fractures in osteopenic and osteoporotic postmenopausal women : Systemic review and meta-analysis. Bone Reports. 13, p. 100729. https://doi.org/10.1016/j.bonr.2020.100729
Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study
Harvey, Nicholas C., Lorentzon, Mattias, Kanis, John A., McCloskey, Eugene and Johansson, Helena. (2020). Incidence of myocardial infarction and associated mortality varies by latitude and season : Findings from a Swedish Registry Study. Journal of Public Health. 42(4), pp. e440-e448. https://doi.org/10.1093/pubmed/fdz131
Grade 1 vertebral fractures identified by densitometric lateral spine imaging predict incident major osteoporotic fracture independently of clinical risk factors and bone mineral density in older women
Johansson, Lisa, Sundh, Daniel, Magnusson, Per, Rukmangatharajan, Komagal, Mellström, Dan, Nilsson, Anna G. and Lorentzon, Mattias. (2020). Grade 1 vertebral fractures identified by densitometric lateral spine imaging predict incident major osteoporotic fracture independently of clinical risk factors and bone mineral density in older women. Journal of Bone and Mineral Research. 35(10), pp. 1942-1951. https://doi.org/10.1002/jbmr.4108
Effect of vitamin d supplementation, omega-3 fatty acid supplementation or a strength-training exercise program on clinical outcomes in older adults : The DO-HEALTH Randomized Clinical Trial
Bischoff-Ferrari, Heike A., Vellas, Bruno, Rizzoli, René, Kressig, Reto W., da Silva, José A. P., Blauth, Michael, Felson, David T., McCloskey, Eugene V., Watzl, Bernhard, Hofbauer, Lorenz C., Felsenberg, Dieter, Willett, Walter C., Dawson-Hughes, Bess, Manson, JoAnn E., Siebert, Uwe, Theiler, Robert, Staehelin, Hannes B., de Godoi Rezende Costa Molino, Caroline, Chocano-Bedoya, Patricia O., ... for the DO-HEALTH Research Group. (2020). Effect of vitamin d supplementation, omega-3 fatty acid supplementation or a strength-training exercise program on clinical outcomes in older adults : The DO-HEALTH Randomized Clinical Trial. JAMA: Journal of the American Medical Association. 324(18), pp. 1855-1868. https://doi.org/10.1001/jama.2020.16909
Bone densitometry worldwide : A global survey by the ISCD and IOF
Clynes, M. A., Westbury, L. D., Dennison, E. M., Kanis, J., Javaid, M. K., Harvey, N. C., Fujita, M., Cooper, C., Leslie, W. D., Shuhart, C. R., The International Society for Clinical Densitometry (ISCD) and The International Osteoporosis Foundation (IOF). (2020). Bone densitometry worldwide : A global survey by the ISCD and IOF. Osteoporosis International. 31, pp. 1779-1786. https://doi.org/10.1007/s00198-020-05435-8
Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures
Kanis, J. A., Johansson, H., Harvey, N. C., Gudnason, V., Sigurdsson, G., Siggeirsdottir, K., Lorentzon, M., Liu, E., Vandenput, L. and McCloskey, E. V.. (2020). Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures. Osteoporosis International. 31(10), pp. 1817-1828. https://doi.org/10.1007/s00198-020-05517-7
FRAX and ethnicity
Kanis, J. A., Cooper, C., Dawson-Hughes, B., Harvey, N. C., Johansson, H., Lorentzon, M., McCloskey, E. V., Reginster, J. Y., Rizzoli, R. and International Osteoporosis Foundation. (2020). FRAX and ethnicity. Osteoporosis International. 31(11), pp. 2063-2067. https://doi.org/10.1007/s00198-020-05631-6
Assessment of cardiovascular safety of anti-osteoporosis drugs
Fuggle, N. R., Cooper, C., Harvey, N. C., Al-Daghri, N., Brandi, M. L., Bruyere, O., Cano, A., Dennison, E. M., Diez-Perez, A., Kaufman, J. M., Palacios, S., Prieto-Alhambra, D., Rozenberg, S., Thomas, T., Tremollieres, F., Rizzoli, R., Kanis, J. A. and Reginster, J. Y.. (2020). Assessment of cardiovascular safety of anti-osteoporosis drugs. Drugs: Education, Prevention and Policy. 80(15), pp. 1537-1552. https://doi.org/10.1007/s40265-020-01364-2
Alternative and complementary therapies in osteoarthritis and cartilage repair
Fuggle, N. R., Cooper, C., Oreffo, R. O. C., Price, A. J., Kaux, J. F., Maheu, E., Cutolo, M., Honvo, G., Conaghan, P. G., Berenbaum, F., Branco, J., Brandi, M. L., Cortet, B., Veronese, N., Kurth, A. A., Matijevic, R., Roth, R., Pelletier, J. P., Martel-Pelletier, J., ... Reginster, J. Y.. (2020). Alternative and complementary therapies in osteoarthritis and cartilage repair. Aging Clinical and Experimental Research. 32(4), pp. 547-560. https://doi.org/10.1007/s40520-020-01515-1
Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial
Parsons, C. M., Harvey, N., Shepstone, L., Kanis, J. A., Lenaghan, E., Clarke, S., Fordham, R., Gittoes, N., Harvey, I., Holland, R., Redmond, N. M., Howe, A., Marshall, T., Peters, T. J., Torgerson, D., O’Neill, T. W., McCloskey, E., Cooper, C., Crabtree, N., ... the Scoop Trial Group. (2020). Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. Osteoporosis International. 31(1), pp. 67-75. https://doi.org/10.1007/s00198-019-05142-z
Risk for hip fracture before and after total knee replacement in Sweden
Vala, C. H., Kärrholm, J., Kanis, J. A., Johansson, H., Sten, S., Sundh, V., Karlsson, M., Lorentzon, M. and Mellström, D.. (2020). Risk for hip fracture before and after total knee replacement in Sweden. Osteoporosis International. 31(5), pp. 887-895. https://doi.org/10.1007/s00198-019-05241-x
Quality of life after fragility fracture in the Russian Federation : Results from the Russian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (ICUROS)
Lesnyak, Olga, Svedbom, Axel, Belova, Ksenia, Dobrovolskaya, Olga, Ershova, Olga, Golubev, Georgij, Grebenshikov, Vyacheslav, Ivanov, Sergej, Kochish, Alexander, Menshikova, Larissa, Nikitinskaya, Oxana, Nurligayanov, Radik, Solodovnikov, Alexander, Toroptsova, Natalia, Varavko, Julia, Zotkin, Eugenij, Borgstrom, Fredrik and Kanis, John A.. (2020). Quality of life after fragility fracture in the Russian Federation : Results from the Russian arm of the International Cost and Utility Related to Osteoporotic Fractures Study (ICUROS). Archives of Osteoporosis. 15(1), pp. 1-9. https://doi.org/10.1007/s11657-020-0699-6
The Importance and Possible Clinical Impact of Measuring Trabecular and Cortical Bone Microstructure to Improve Fracture Risk Prediction
Mattias Lorentzon. (2020). The Importance and Possible Clinical Impact of Measuring Trabecular and Cortical Bone Microstructure to Improve Fracture Risk Prediction. Journal of Bone and Mineral Research. 35(5), pp. 831-832. https://doi.org/10.1002/jbmr.3940
Secondary fracture prevention : Consensus clinical recommendations from a multistakeholder coalition
Conley, Robert B., Adib, Gemma, Adler, Robert A., Åkesson, Kristina E., Alexander, Ivy M., Amenta, Kelly C., Blank, Robert D., Brox, William Timothy, Carmody, Emily E., Chapman-Novakofski, Karen, Clarke, Bart L., Cody, Kathleen M., Cooper, Cyrus, Crandall, Carolyn J., Dirschl, Douglas R., Eagen, Thomas J., Elderkin, Ann L., Fujita, Masaki, Greenspan, Susan L., ... Kiel, Douglas P.. (2020). Secondary fracture prevention : Consensus clinical recommendations from a multistakeholder coalition. Journal of Bone and Mineral Research. 35(1), pp. 36-52. https://doi.org/10.1002/jbmr.3877
Loss in DXA-estimated total body lean mass but not fat mass predicts incident major osteoporotic fracture and hip fracture independently from FRAX : A registry-based cohort study
Leslie, William D., Schousboe, John T., Morin, Suzanne N., Martineau, Patrick, Lix, Lisa M., Johansson, Helena, McCloskey, Eugene V., Harvey, Nicholas C. and Kanis, John A.. (2020). Loss in DXA-estimated total body lean mass but not fat mass predicts incident major osteoporotic fracture and hip fracture independently from FRAX : A registry-based cohort study. Archives of Osteoporosis. 15, p. Article 96. https://doi.org/10.1007/s11657-020-00773-w
Long-term cost-effectiveness of screening for fracture risk in a UK primary care setting : The SCOOP Study
Söreskog, E., Borgström, F., Shepstone, L., Clarke, S., Cooper, C., Harvey, I., Harvey, N. C., Howe, A., Johansson, H., Marshall, T., O’Neill, T. W., Peters, T. J., Redmond, N. M., Turner, D., Holland, R., McCloskey, E., Kanis, J. A., Heawood, A., Crabtree, N., ... SCOOP Study Team. (2020). Long-term cost-effectiveness of screening for fracture risk in a UK primary care setting : The SCOOP Study. Osteoporosis International. 31, pp. 1499-1506. https://doi.org/10.1007/s00198-020-05372-6
Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
Serge Rozenberg, Nasser M Al-Daghri, M. Aubertin-Leheudre, Maria Luisa Brandi, A. Cano, Peter Collins, C. Cooper, A. R. Genazzani, T. Hillard, John Kanis, J. -M. Kaufman, I. Lambrinoudaki, A. Laslop, Eugene McCloskey, Santiago Palacios, D. Prieto-Alhambra, Jean Yves Reginster, Rene Rizzoli, Giuseppe Rosano, ... Nicholas C. Harvey. (2020). Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis? Osteoporosis International. 31(12), pp. 2271-2286. https://doi.org/10.1007/s00198-020-05497-8
Increased risk for hip fracture after death of a spouse - further support for bereavement frailty?
Vala, C. H., Lorentzon, M., Sundh, V., Johansson, H., Lewerin, C., Sten, S., Karlsson, M., Ohlsson, C., Johansson, B., Kanis, J. A. and Mellström, D.. (2020). Increased risk for hip fracture after death of a spouse - further support for bereavement frailty? Osteoporosis International. 31, pp. 485-492. https://doi.org/10.1007/s00198-019-05242-w
Harmonization of commercial assays for PINP ; the way forward
Vasikaran, S. D., Bhattoa, H. P., Eastell, R., Heijboer, A. C., Jørgensen, N. R., Makris, K., Ulmer, C., Kanis, J. A., Cooper, C., Silverman, S. and Cavalier, E.. (2020). Harmonization of commercial assays for PINP ; the way forward. Osteoporosis International. 31, pp. 409-412. https://doi.org/10.1007/s00198-020-05310-6
Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
John Kanis, Nicholas C. Harvey, Eugene McCloskey, Olivier Bruyere, N. Veronese, Mattias Lorentzon, C. Cooper, Rene Rizzoli, G. Adib, Nasser M. Al-Daghri, C. Campusano, Manju Chandran, Bess Dawson-Hughes, M. K. Javaid, F. Jiwa, Helena Johansson, J K Lee, Enwu Liu, D Messina, ... Jean Yves Reginster. (2020). Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International. 31, pp. 1-12. https://doi.org/10.1007/s00198-019-05176-3
Fragility fractures in Europe : Burden, management and opportunities 
Borgström, Fredrik, Karlsson, Linda, Ortsäter, Gustav, Norton, Nicolas, Halbout, Philippe, Cooper, Cyrus, Lorentzon, Mattias, McCloskey, Eugene V., Harvey, Nicholas C., Javaid, Muhamamd K., Kanis, John A. and International Osteoporosis Foundation. (2020). Fragility fractures in Europe : Burden, management and opportunities . Archives of Osteoporosis. 15(59), pp. 1-21. https://doi.org/10.1007/s11657-020-0706-y
Fracture risk following high-trauma versus low-trauma fracture : A registry-based cohort study
Leslie, W. D., Schousboe, J. T., Morin, S. N., Martineau, P., Lix, L. M., Johansson, H., McCloskey, E. V., Harvey, N. C. and Kanis, J. A.. (2020). Fracture risk following high-trauma versus low-trauma fracture : A registry-based cohort study. Osteoporosis International. 31, pp. 1059-1067. https://doi.org/10.1007/s00198-019-05274-2
European Biological Variation Study (EuBIVAS) : Within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein - A cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism
Cavalier, E., Lukas, P., Bottani, M., Aarsand, A. K., Ceriotti, F., Coşkun, A., Díaz-Garzón, J., Fernàndez-Calle, P., Guerra, E., Locatelli, M., Sandberg, S., Carobene, A., European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and IOF-IFCC Committee on Bone Metabolism, Cooper, C. and Kanis, J. A.. (2020). European Biological Variation Study (EuBIVAS) : Within- and between-subject biological variation estimates of β-isomerized C-terminal telopeptide of type I collagen (β-CTX), N-terminal propeptide of type I collagen (PINP), osteocalcin, intact fibroblast growth factor 23 and uncarboxylated-unphosphorylated matrix-Gla protein - A cooperation between the EFLM Working Group on Biological Variation and the International Osteoporosis Foundation-International Federation of Clinical Chemistry Committee on Bone Metabolism. Osteoporosis International. 31, pp. 1461-1470. https://doi.org/10.1007/s00198-020-05362-8
Estimation of long-term efficacy of denosumab treatment in postmenopausal women with osteoporosis : A FRAX- and virtual twin-based post hoc analysis from FREEDOM and FREEDOM Extension trials
Siris, Ethel, McDermott, Michele, Pannacciulli, Nicola, Miller, Paul D., Lewiecki, E. Michael, Chapurlat, Roland, Jódar-Gimeno, Esteban, Huang, Shuang and Kanis, John A.. (2020). Estimation of long-term efficacy of denosumab treatment in postmenopausal women with osteoporosis : A FRAX- and virtual twin-based post hoc analysis from FREEDOM and FREEDOM Extension trials. JBMR Plus. 4(4), pp. 1-5. https://doi.org/10.1002/jbm4.10348
Epidemiology of osteoporotic fracture in Moldova and development of a country-specific FRAX model
Zakroyeva, Alla, Lesnyak, Olga, Cazac, Victor, Groppa, Liliana, Russu, Eugen, Chislari, Lia, Rotaru, Larisa, Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene, Lorentzon, Mattis and Kanis, John. (2020). Epidemiology of osteoporotic fracture in Moldova and development of a country-specific FRAX model. Archives of Osteoporosis. 15, pp. 1-8. https://doi.org/10.1007/s11657-019-0669-z
Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model
Issayeva, S., Lesnyak, O., Zakroyeva, A., Issayeva, B., Dilmanova, D., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). Epidemiology of osteoporotic fracture in Kazakhstan and development of a country specific FRAX model. Archives of Osteoporosis. 15, pp. 1-8. https://doi.org/10.1007/s11657-020-0701-3
Development of a polygenic risk score to improve screening for fracture risk : A genetic risk prediction study
Forgetta, Vincenzo, Keller-Baruch, Julyan, Forest, Marie, Durand, Audrey, Bhatnagar, Sahir, Kemp, John P., Nethander, Maria, Evans, Daniel, Morris, John A., Kiel, Douglas P., Rivadeneira, Fernando, Johansson, Helena, Harvey, Nicholas C., Mellström, Dan, Karlsson, Magnus, Cooper, Cyrus, Evans, David M., Clarke, Robert, Kanis, John, A., ... Richards, J. Brent. (2020). Development of a polygenic risk score to improve screening for fracture risk : A genetic risk prediction study. PLoS Medicine. 17(7), pp. 1-19. https://doi.org/10.1371/journal.pmed.1003152
A surrogate FRAX model for the Kyrgyz Republic
Lesnyak, O., Zakroyeva, A., Lobanchenko, O., Johansson, H., Liu, E., Lorentzon, M., Harvey, N. C., McCloskey, E. and Kanis, J. A.. (2020). A surrogate FRAX model for the Kyrgyz Republic. Archives of Osteoporosis. 15, pp. 1-5. https://doi.org/10.1007/s11657-020-00743-2
Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model
Kirilova, E., Johansson, H., Kirilov, N., Vladeva, S., Petranova, T., Kolarov, Z., Liu, E., Lorentzon, M., Vandenput, L., Harvey, N. C., McCloskey, E. and Kanis, John A.. (2020). Epidemiology of hip fractures in Bulgaria: Development of a country-specific FRAX model. Archives of Osteoporosis. 15(28), pp. 1 - 7. https://doi.org/10.1007/s11657-020-0710-2
Association between recurrent fracture risk and implementation of fracture liaison services in four Swedish hospitals : A cohort study
Axelsson, Kristian F., Johansson, Helena, Lundh, Dan, Möller, Michael and Lorentzon, Mattias. (2020). Association between recurrent fracture risk and implementation of fracture liaison services in four Swedish hospitals : A cohort study. The Lancet Diabetes & Endocrinology. 35(7), pp. 1216-1223. https://doi.org/10.1002/jbmr.3990
A decade of FRAX: How has it changed the management of osteoporosis?
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Vandenput, Liesbeth, Lorentzon, Mattias, Leslie, William D. and McCloskey, Eugene V.. (2020). A decade of FRAX: How has it changed the management of osteoporosis? Aging Clinical and Experimental Research. 32(2), pp. 187 - 196. https://doi.org/10.1007/s40520-019-01432-y
Use of age-dependent FRAX-based intervention thresholds for Singapore
Kanis, John A., Chandran, Manju, Chionh, Siok Bee, Ganeson, Ganga, Harvey, Nicholas C., Koh, Woon-Puay, Kwok, Timothy, Lau, Tang Ching, Liu, Enwu, Lorentzon, Mattias, McCloskey, Eugene V., Tan, Kelvin Bryan, Vandenput, Liesbeth and Johansson, Helena. (2020). Use of age-dependent FRAX-based intervention thresholds for Singapore. Archives of Osteoporosis. 15, pp. 1 - 10. https://doi.org/10.1007/s11657-020-00782-9
Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study
Coster, Marcus E., Karlsson, Magnus, Ohlsson, Claes, Mellstrom, Dan, Lorentzon, Mattias, Ribom, Eva and Rosengren, Bjorn. (2020). Physical function tests predict incident falls: A prospective study of 2969 men in the Swedish Osteoporotic Fractures in Men study. Scandinavian Journal of Public Health. 48(4), pp. 436 - 441. https://doi.org/10.1177/1403494818801628
BMD-related genetic risk scores predict site-specific fractures as well as trabecular and cortical bone microstructure
Nethander, Maria, Pettersson-Kymmer, Ulrika, Vandenput, Liesbeth, Lorentzon, Mattias, Karlsson, Magnus, Mellström, Dan and Ohlsson, Claes. (2020). BMD-related genetic risk scores predict site-specific fractures as well as trabecular and cortical bone microstructure. The Journal of Clinical Endocrinology and Metabolism. 105(4), pp. e1344-e1357. https://doi.org/10.1210/clinem/dgaa082
High plasma erythropoietin predicts incident fractures in elderly men with normal renal function: The MrOS Sweden cohort
Kristjansdottir, Hallgerdur Lind, Lewerin, Catharina, Lerner, Ulf H., Herlitz, Hans, Johansson, Peter, Johansson, Helena, Karlsson, Magnus, Lorentzon, Mattias, Ohlsson, Claes, Ljunggren, Östen and Mellstrom, Dan. (2020). High plasma erythropoietin predicts incident fractures in elderly men with normal renal function: The MrOS Sweden cohort. Journal of Bone and Mineral Research. 35(2), pp. 298 - 305. https://doi.org/10.1002/jbmr.3900
Disentangling the genetics of lean mass
Karasik, David, Zillikens, M. Carola, Hsu, Yi Hsiang, Aghdassi, Ali, Åkesson, Kristina, Amin, Najaf, Barroso, Inês, Bennett, David A., Bertram, Lars, Bochud, Murielle, Borecki, Ingrid, Broer, Linda, Buchman, Aron S., Byberg, Liisa, Campbell, Harry, Campos-Obando, Natalia, Cauley, Jane, Cawthon, Peggy M, Chambers, John, ... Ohlsson, Claes. (2019). Disentangling the genetics of lean mass. American Journal of Clinical Nutrition. 109(2), pp. 276-278. https://doi.org/10.1093/ajcn/nqy272
Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC) : A prospective study
Samelson, Elizabeth J., Broe, Kerry E., Xu, Hanfei, Yang, Laiji, Boyd, Steven, Biver, Emmanuel, Szulc, Pawel, Adachi, Jonathan, Amin, Shreyasee, Atkinson, Elizabeth, Berger, Claudie, Burt, Lauren, Chapurlat, Roland, Chevalley, Thierry, Ferrari, Serge, Goltzman, David, Hanley, David A., Hannan, Marian T., Khosla, Sundeep, ... Bouxsein, Mary L.. (2019). Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC) : A prospective study. The Lancet Diabetes & Endocrinology. 7(1), pp. 34-43. https://doi.org/10.1016/S2213-8587(18)30308-5
East meets West: current practices and policies in the management of musculoskeletal aging
Weibo Xia, Cyrus Cooper, Mei Li, Ling Xu, Rene Rizzoli, Mei Zhu, Hua Lin, John Beard, Yue Ding, Wei Yu, Etienne Cavalier, Zhenlin Zhang, John Kanis, Qun Cheng, Quimei Wang and Jean-Yves Reginster. (2019). East meets West: current practices and policies in the management of musculoskeletal aging. Aging Clinical and Experimental Research. 31(10), pp. 1351-1373. https://doi.org/10.1007/s40520-019-01282-8
Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF)
Mickaël Hiligsmann, D Cornelissen, B Vrijens, Bo Abrahamsen, Nasser M Al-Daghri, Emmanuel Biver, Maria Luisa Brandi, Olivier Bruyere, N. Burlet, C. Cooper, Bernard Cortet, Elaine M. Dennison, Aldolfo Diez-Perez, Andrea Ildiko Gasparik, A Grosso, P Hadji, P. Halbout, John Kanis, J -M Kaufman, ... Jean Yves Reginster. (2019). Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF). Osteoporosis International. 30(11), pp. 2155-2165. https://doi.org/10.1007/s00198-019-05104-5
Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis
Mattias Lorentzon, Jaime Branco, Maria Luisa Brandi, Olivier Bruyere, Roland D Chapurlat, Cyrus Cooper, Bernard Cortet, Aldolfo Diez-Perez, Serge L Ferrari, Andrea Ildiko Gasparik, Markus Herrmann, N. R. Jorgensen, John Kanis, Jean-Marc Kaufman, A. Laslop, Medea Locquet, Radmila Matijevic, Eugene McCloskey, Salvatore Minisola, ... Etienne Cavalier. (2019). Algorithm for the Use of Biochemical Markers of Bone Turnover in the Diagnosis, Assessment and Follow-Up of Treatment for Osteoporosis. Advances in Therapy. 36(10), pp. 2811-2824. https://doi.org/10.1007/s12325-019-01063-9
Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, J. A., Cooper, C., Rizzoli, R. and Reginster, J.-Y.. (2019). Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Aging Clinical and Experimental Research. 31(1), pp. 15-17. https://doi.org/10.1007/s40520-018-1109-4
Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation
M. Hiligsmann, J.-Y. Reginster, A.N.A. Tosteson, S.V. Bukata, K.G. Saag, D.T. Gold, P. Halbout, F. Jiwa, E.M. Lewiecki, D. Pinto, J.D. Adachi, N. Al-Daghri, O. Bruyère, M. Chandran, C. Cooper, N.C. Harvey, T.A. Einhorn, J.A. Kanis, D.L. Kendler, ... S. Silverman. (2019). Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation. Osteoporosis International. 30(1), pp. 45-57. https://doi.org/10.1007/s00198-018-4744-x
Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
Maarten de Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G. Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Araujo de Carvalho, Mary Barker, Nicola Bedlington, Maria Luisa Brandi, Olivier Bruyère, Nansa Burlet, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, ... Jean-Yves Reginster. (2019). Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). Aging Clinical and Experimental Research. 31(7), pp. 905-915. https://doi.org/10.1007/s40520-019-01193-8
Sarcopenia: revised European consensus on definition and diagnosis
Alfonso J. Cruz-Jentoft, Gülistan Bahat, Jürgen Bauer, Yves Boirie, Olivier Bruyère, Tommy Cederholm, Cyrus Cooper, Francesco Landi, Yves Rolland, Avan Aihie Sayer, Stéphane M. Schneider, Cornel C. Sieber, Eva Topinkova, Maurits Vandewoude, Marjolein Visser, Mauro Zamboni, John Kanis, Writing Group For The European Working Group On Sarcopenia In Older People 2 (EWGSOP2) and The Extended Group For EWGSOP2*. (2019). Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing. 48(1), pp. 16-31. https://doi.org/10.1093/ageing/afy169
Assessment of Muscle Function and Physical Performance in Daily Clinical Practice
Charlotte Beaudart, Yves Rolland, Alfonso J. Cruz-Jentoft, Jürgen M. Bauer, Cornel Sieber, Cyrus Cooper, Nasser Al-Daghri, Islene Araujo de Carvalho, Ivan Bautmans, Roberto Bernabei, Olivier Bruyère, Matteo Cesari, Antonio Cherubini, Bess Dawson-Hughes, John A. Kanis, Jean-Marc Kaufman, Francesco Landi, Stefania Maggi, Eugene McCloskey, ... Roger A. Fielding. (2019). Assessment of Muscle Function and Physical Performance in Daily Clinical Practice. Calcified Tissue International. 105(1), pp. 1-13. https://doi.org/10.1007/s00223-019-00545-w
Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review
Bauer, Jurgen M., Cruz-Jentoft, Alfonso J., Fielding, Roger A., Kanis, John A., Reginster, Jean-Yves, Bruyere, Olivier, Cesari, Matteo, Chapurlat, Roland, Al-Daghri, Nasser, Dennison, Elaine M., Kaufman, Jean-Marc, Landi, Francesco, Laslop, Andrea, Locquet, Medea, Maggi, Stefania, McCloskey, Eugene, Perna, Simone, Rizzoli, Rene, Rolland, Yves, ... Cooper, Cyrus. (2019). Is there enough evidence for osteosarcopenic obesity as a distinct entity? A critical literature review. Calcified Tissue International. 105, pp. 109 - 124. https://doi.org/10.1007/s00223-019-00561-w
Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults
Gratza, S. K., Chocano-Bedoya, Patricia O., Orav, E. J., Fischbacher, M., Freystätter, G., Theiler, Robert, Egli, Andreas, Kressig, R. W., Kanis, John A. and Bischoff-Ferrari, Heike A.. (2019). Influence of fall environment and fall direction on risk of injury among pre-frail and frail adults. Osteoporosis International. 30, pp. 2205 - 2215. https://doi.org/10.1007/s00198-019-05110-7
Executive summary of the European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, J. A., Cooper, C., Rizzoli, R. and Reginster, J.-Y.. (2019). Executive summary of the European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Calcified Tissue International. 104(3), pp. 235-238. https://doi.org/10.1007/s00223-018-00512-x
Treating osteoporosis to prevent fractures: Current concepts and future developments
Lorentzon, Mattias. (2019). Treating osteoporosis to prevent fractures: Current concepts and future developments. Journal of Internal Medicine. 285(4), pp. 381 - 394. https://doi.org/10.1111/joim.12873
Mendelian randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures
Zheng, Jie, Maerz, Winfried, Gergei, Ingrid, Kleber, Marcus E., Drechsler, Christiane, Wanner, Christoph, Brandenburg, Vincent, Reppe, Sjur, Gautvik, Kaare M., Medina-Gomez, Carolina, Shevroja, Enisa, Gilly, Arthur, Park, Young-Chan, Dedoussis, George, Zeggini, Eleftheria, Lorentzon, Mattias, Henning, Petra, Lerner, Ulf H., Nilsson, Karin H., ... Tobias, Jonathan H.. (2019). Mendelian randomization analysis reveals a causal influence of circulating sclerostin levels on bone mineral density and fractures. Journal of Bone and Mineral Research. 34(10), pp. 1824 - 1836. https://doi.org/10.1002/jbmr.3803
European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., Cooper, Cyrus, Rizzoli, Rene and Reginster, Jean-Yves. (2019). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 30(1), pp. 3 - 44. https://doi.org/10.1007/s00198-018-4704-5
Extensive undertreatment of osteoporosis in older Swedish women
Lorentzon, Mattias, Nilsson, A. G., Johansson, Helena, Kanis, John A., Mellström, Dan and Sundh, D.. (2019). Extensive undertreatment of osteoporosis in older Swedish women. Osteoporosis International. 30(6), pp. 1297 - 1305. https://doi.org/10.1007/s00198-019-04872-4
Assessing the risk of osteoporotic fractures: The Ecuadorian FRAX model
Lopez Gavilanez, Enrique, Johansson, Helena, McCloskey, Eugene, Harvey, Nicholas C., Bajana, Angel Segale, Blum, Dennise Marriott, Grijalva, Mario Navarro, Curiel, Manuel Diaz and Kanis, John A.. (2019). Assessing the risk of osteoporotic fractures: The Ecuadorian FRAX model. Archives of Osteoporosis. 14(93), pp. 1 - 8. https://doi.org/10.1007/s11657-019-0644-8
Fracture risk in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Niraula, Saroj, McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Fracture risk in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study. The Oncologist. 24(11), pp. 1432 - 1438. https://doi.org/10.1634/theoncologist.2019-0149
Fracture prediction from self-reported falls in routine clinical practice: a registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa, Martineau, Patrick, Bryanton, M., McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Fracture prediction from self-reported falls in routine clinical practice: a registry-based cohort study. Osteoporosis International. 30, pp. 2195 - 2203. https://doi.org/10.1007/s00198-019-05106-3
Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia
Harvey, Nicholas C., Kanis, John A., Liu, Enwu, Johansson, Helena, Lorentzon, Mattias and McCloskey, Eugene. (2019). Appendicular lean mass and fracture risk assessment: Implications for FRAX(R) and sarcopenia. Osteoporosis International. 30(3), pp. 537 - 539. https://doi.org/10.1007/s00198-019-04904-z
Temporal changes in access to FRAX in Thailand between 2010 and 2018
Chotiyarnwong, Pojchong, Harvey, Nicholas C., Johansson, Helena, Liu, Enwu, Lorentzon, Mattias, Kanis, John A. and McCloskey, Eugene V.. (2019). Temporal changes in access to FRAX in Thailand between 2010 and 2018. Archives of Osteoporosis. 14(1), pp. 1 - 7. https://doi.org/10.1007/s11657-019-0613-2
Patients with prostate cancer and androgen deprivation therapy have increased risk of fractures—a study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO)
Wallander, M., Axelsson, K. F., Lundh, D. and Lorentzon, Mattias. (2019). Patients with prostate cancer and androgen deprivation therapy have increased risk of fractures—a study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO). Osteoporosis International. 30(1), pp. 115 - 125. https://doi.org/10.1007/s00198-018-4722-3
Decreased physical health-related quality of life—a persisting state for older women with clinical vertebral fracture
Johansson, L., Svensson, H. K., Karlsson, J., Olsson, L. E., Mellström, Dan, Lorentzon, Mattias and Sundh, D.. (2019). Decreased physical health-related quality of life—a persisting state for older women with clinical vertebral fracture. Osteoporosis International. 30, pp. 1961 - 1971. https://doi.org/10.1007/s00198-019-05044-0
Effect of abaloparatide on vertebral,nonvertebral, major osteoporotic and clinical fractures in a subset of postmenopausal women at increased risk of fracture by FRAX probability
McCloskey, Eugene V., Fitzpatrick, Lorraine, Hu, M.-Y., Williams, G. and Kanis, John A.. (2019). Effect of abaloparatide on vertebral,nonvertebral, major osteoporotic and clinical fractures in a subset of postmenopausal women at increased risk of fracture by FRAX probability. Archives of Osteoporosis. 14(1), pp. 1 - 7. https://doi.org/10.1007/s11657-019-0564-7
Meta-analysis of genomewide association studies reveals genetic variants for hip bone geometry
Hsu, Yi-Hsiang, Estrada, Karol, Evangelou, Evangelos, Ackert-Bicknell, Cheryl, Åkesson, Kristina, Beck, Thomas, Brown, Suzanne J., Capellini, Terence, Carbone, Laura, Cauley, Jane, Cheung, Ching-Lung, Cummings, Steven R., Czerwinski, Stefan, Demissie, Serkalem, Econs, Michael J., Evans, Daniel S., Farber, Charles, Gautvik, Kaare M., Harris, Tamara, ... Karasik, David. (2019). Meta-analysis of genomewide association studies reveals genetic variants for hip bone geometry. Journal of Bone and Mineral Research. 34(7), pp. 1284 - 1296. https://doi.org/10.1002/jbmr.3698
The prevention of glucocorticoid-induced osteoporosis in patients with immune thrombocytopenia receiving steroids: A British Society for Haematology Good Practice Paper
Hill, Quentin A., Grainger, John D., Thachil, Jecko, Provan, Drew, Evans, Gillian, Garg, Mamta, Bradbury, Charlotte, Bagot, Catherine, Kanis, John A. and Compston, Juliet E.. (2019). The prevention of glucocorticoid-induced osteoporosis in patients with immune thrombocytopenia receiving steroids: A British Society for Haematology Good Practice Paper. British Journal of Haematology. 185(3), pp. 410 - 417. https://doi.org/10.1111/bjh.15735
Performance of FRAX in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Niraula, Saroj, McCloskey, Eugene V., Johansson, Helena, Harvey, Nicholas C. and Kanis, John A.. (2019). Performance of FRAX in women with breast cancer initiating aromatase inhibitor therapy: A registry-based cohort study. Journal of Bone and Mineral Research. 34(8), pp. 1428 - 1435. https://doi.org/10.1002/jbmr.3726
Fracture risk following intermission of osteoporosis therapy
Dennison, Elaine M., Cooper, Cyrus, Kanis, John A., Bruyère, O., Silverman, S., McCloskey, Eugene, Abrahamsen, Bo, Prieto-Alhambra, D. and Ferrari, Serge L.. (2019). Fracture risk following intermission of osteoporosis therapy. Osteoporosis International. 30(9), pp. 1733 - 1743. https://doi.org/10.1007/s00198-019-05002-w
FRAX-based intervention and assessment thresholds for osteoporosis in Iran
Khashayar, P., Keshtkar, A., Ostovar, A., Larijani, B., Johansson, H., Harvey, N. C., Lorentzon, M., McCloskey, E. and Kanis, John A.. (2019). FRAX-based intervention and assessment thresholds for osteoporosis in Iran. Osteoporosis International. 30, pp. 2225-2230. https://doi.org/10.1007/s00198-019-05078-4
The Fracture Risk Assessment Tool (FRAX®) predicts fracture risk in patients with chronic kidney disease
Whitlock, Reid H., Leslie, William D., Shaw, James, Rigatto, Claudio, Thorlacius, Laurel, Komenda, Paul, Collister, David, Kanis, John A. and Tangri, Navdeep. (2019). The Fracture Risk Assessment Tool (FRAX®) predicts fracture risk in patients with chronic kidney disease. Kidney International. 95(2), pp. 447 - 454. https://doi.org/10.1016/j.kint.2018.09.022
Association between cortical bone microstructure and statin use in older women
Larsson, Berit A. M., Sundh, Daniel, Mellström, Dan, Axelsson, Kristian F., Nilsson, Anna G. and Lorentzon, Mattias. (2019). Association between cortical bone microstructure and statin use in older women. The Journal of Clinical Endocrinology and Metabolism. 104(2), pp. 250 - 257. https://doi.org/10.1210/jc.2018-02054
FRAX: Assessment of Fracture Risk
Kanis, John, McCloskey, Eugene, Harvey, Nicholas C. and Leslie, William D.. (2019). FRAX: Assessment of Fracture Risk. In In J. P. Bilezikian (Ed.). Primer on the metabolic bone diseases and disorders of mineral metabolism pp. 331 - 339 Wiley-Blackwell. https://doi.org/10.1002/9781119266594.ch41
A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type i procollagen (PINP): A report from the IFCC-IOF Joint Committee for Bone Metabolism
Cavalier, Etienne, Eastell, Richard, Jørgensen, Niklas Rye, Makris, Konstantinos, Tournis, Symeon, Vasikaran, Samuel, Kanis, John A., Cooper, Cyrus, Pottel, Hans and Morris, Howard A.. (2019). A multicenter study to evaluate harmonization of assays for N-terminal propeptide of type i procollagen (PINP): A report from the IFCC-IOF Joint Committee for Bone Metabolism. Clinical Chemistry and Laboratory Medicine. 57(10), pp. 1546 - 1555. https://doi.org/10.1515/cclm-2019-0174
Osteoporosis : Treatment gaps and health economics
Harvey, Nicholas C.W., McCloskey, Eugene V., Rizzoli, Rene, Kanis, John A., Cooper, Cyrus and Reginster, Jean-Yves. (2018). Osteoporosis : Treatment gaps and health economics. In In Martini, Luciano (Ed.). Encyclopedia of Endocrine Diseases pp. 288 - 295 Elsevier. https://doi.org/10.1016/B978-0-12-801238-3.99202-X
Genome analyses of > 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, ... Alizadeh, Behrooz Z.. (2018). Genome analyses of > 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders. American Journal of Human Genetics. 103(5), pp. 691-706. https://doi.org/10.1016/j.ajhg.2018.09.009
Assessment of the genetic and clinical determinants of fracture risk: Genome wide association and mendelian randomisation study
Trajanoska, Katerina, Morris, John A., Oei, Ling, Zheng, Hou-Feng, Evans, David M., Kiel, Douglas P., Ohlsson, Claes, Richards, J. Brent, Rivadeneira, Fernando, on behalf of the GEFOS/GENOMOS consortium and the 23andMe research team*, Lorentzon, Mattias and Vandenput, Liesbeth. (2018). Assessment of the genetic and clinical determinants of fracture risk: Genome wide association and mendelian randomisation study. BMJ. 362, p. Article k3225. https://doi.org/10.1136/bmj.k3225
High serum serotonin predicts increased risk for hip fracture and nonvertebral osteoporotic fractures: The MrOS Sweden Study
Kristjansdottir, Hallgerdur Lind, Lewerin, C., Lerner, Ulf H., Waern, Ewa, Johansson, Helena, Sundh, Daniel, Karlsson, Magnus, Cummings, Steven R., Zetterberg, Henrik, Lorentzon, Mattias, Ohlsson, Claes and Mellstrom, Dan. (2018). High serum serotonin predicts increased risk for hip fracture and nonvertebral osteoporotic fractures: The MrOS Sweden Study. Journal of Bone and Mineral Research. 33(9), pp. 1560 - 1567. https://doi.org/10.1002/jbmr.3443
High-impact mechanical loading increases bone material strength in postmenopausal women—a 3-month intervention study
Sundh, Daniel, Nilsson, Martin, Zoulakis, Michail, Pasco, Courtney, Yilmaz, Melis, Kazakia, Galateia J., Hellgren, Martin and Lorentzon, Mattias. (2018). High-impact mechanical loading increases bone material strength in postmenopausal women—a 3-month intervention study. Journal of Bone and Mineral Research. 33(7), pp. 1242 - 1251. https://doi.org/10.1002/jbmr.3431
Comparison of methods for improving fracture risk assessment in diabetes: the Manitoba BMD Registry
Leslie, William D., Johansson, Helena, Mccloskey, Eugene V., Harvey, Nicholas C., Kanis, John and Hans, Didier. (2018). Comparison of methods for improving fracture risk assessment in diabetes: the Manitoba BMD Registry. Journal of Bone and Mineral Research. 33(11), pp. 1923 - 1930. https://doi.org/10.1002/jbmr.3538
Understanding osteoporotic pain and its pharmacological treatment: supplementary presentation
Vellucci, R., Terenzi, R., Kanis, John, Kress, H.G., Mediati, R.D., Reginster, Jean Y., Rizzoli, Rene and Brandi, Maria L.. (2018). Understanding osteoporotic pain and its pharmacological treatment: supplementary presentation. Osteoporosis International. 29(9), pp. 2153 - 2154. https://doi.org/10.1007/s00198-018-4536-3
Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: A randomized, placebo-controlled, double-blind, clinical trial
Nilsson, A. G., Sundh, D., Bäckhed, F. and Lorentzon, Mattias. (2018). Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: A randomized, placebo-controlled, double-blind, clinical trial. Journal of Internal Medicine. 284(3), pp. 307 - 317. https://doi.org/10.1111/joim.12805
Which method of fall ascertainment captures the most falls in prefrail and frail seniors?
Teister, Corina J., Chocano-Bedoya, Patricia O., Orav, Endel J., Dawson-Hughes, Bess, Meyer, Ursina, Meyer, Otto W., Freystaetter, Gregor, Gagesch, Michael, Rizzoli, Rene, Egli, Andreas, Theiler, Robert, Kanis, John A. and Bischoff-Ferrari, Heike A.. (2018). Which method of fall ascertainment captures the most falls in prefrail and frail seniors? American Journal of Epidemiology. 187(10), pp. 2243 - 2251. https://doi.org/10.1093/aje/kwy113
Falls predict fractures independently of FRAX probability: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Oden, Anders, Orwoll, E., Lapidus, Jodi, Kwok, T., Karlsson, Magnus, Rosengren, Björn E., Ljunggren, Östen, Cooper, Cyrus, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes, Mellström, Dan and Johansson, Helena. (2018). Falls predict fractures independently of FRAX probability: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study. Journal of Bone and Mineral Research. 33(3), pp. 510 - 516. https://doi.org/10.1002/jbmr.3331
Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464)
Harvey, Nicholas C., McCloskey, Eugene, Kanis, John, Compston, J E. and Cooper, Cath. (2018). Cost-effective but clinically inapproriate: new nice intervention thresholds in osteoporosis (technology appraisal 464). Osteoporosis International. 29(7), pp. 1511 - 1513. https://doi.org/10.1007/s00198-018-4505-x
Management of patients with high baseline hip fracture risk by FRAX reduces hip fractures—a post hoc analysis of the scoop study
McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Shepstone, L., Lenaghan, E., Fordham, Ric, Harvey, I., Howe, Amanda, Cooper, Cyrus, Clarke, Shane, Gittoes, Neil, Heawood, A., Holland, R., Marshall, Tarnya, O'Neill, T. W., Peters, T. J., Redmond, Niamh, Torgerson, David and Kanis, John A.. (2018). Management of patients with high baseline hip fracture risk by FRAX reduces hip fractures—a post hoc analysis of the scoop study. Journal of Bone and Mineral Research. 33(6), pp. 1020 - 1026. https://doi.org/10.1002/jbmr.3411
Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects
Medina-Gómez, Carolina, Kemp, John P., Trajanoska, Katerina, Luan, Jian'an, Chesi, Alessandra, Ahluwalia, Tarunveer S., Mook-Kanamori, Dennis O., Ham, Annelies C., Hartwig, Fernando P., Evans, Daniel S., Joro, Raimo, Nedeljkovic, Ivana, Zheng, Hou-Feng, Zhu, Kun, Atalay, Mustafa, Liu, Ching-Ti, Nethander, Maria, Broer, Linda, Porleifsson, Gudmar, ... Rivadeneira, Fernando. (2018). Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects. American Journal of Human Genetics. 102(1), pp. 88 - 102. https://doi.org/10.1016/j.ajhg.2017.12.005
Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighboring country models
Ramanau, H., Chernyanin, I., Rudenka, E., Lesnyak, Olga, Zakroyeva, A., Bilezikian, John P., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene and Kanis, John A.. (2018). Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighboring country models. Archives of Osteoporosis. 13(1), pp. 1 - 5. https://doi.org/10.1007/s11657-018-0454-4
A brief history of FRAX
Kanis, John A., Johansson, Helena, Harvey, Nicholas C. and McCloskey, Eugene V.. (2018). A brief history of FRAX. Archives of Osteoporosis. 13(1), p. Article 118. https://doi.org/10.1007/s11657-018-0510-0
In which patients does lumbar spine trabecular bone score (TBS) have the largest effect?
Martineau, Patrick, Leslie, William D., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene, Hans, Didier and Kanis, John A.. (2018). In which patients does lumbar spine trabecular bone score (TBS) have the largest effect? Bone. 113, pp. 161 - 168. https://doi.org/10.1016/j.bone.2018.05.026
Measures of physical performance and muscle strength as predictors of fracture risk independent of FRAX, falls, and aBMD: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study
Harvey, Nicholas C., Oden, Anders, Orwoll, E., Lapidus, Jodi, Kwok, T., Karlsson, Magnus, Rosengren, Björn E., Ribom, Eva, Cooper, Cyrus, Cawthon, Peggy M., Kanis, John A., Ohlsson, Claes, Mellström, Dan, Johansson, Helena and McCloskey, Eugene. (2018). Measures of physical performance and muscle strength as predictors of fracture risk independent of FRAX, falls, and aBMD: A meta-analysis of the Osteoporotic Fractures in Men (MrOS) Study. Journal of Bone and Mineral Research. 33(12), pp. 2150 - 2157. https://doi.org/10.1002/jbmr.3556
Assessment of fracture risk
McCloskey, Eugene, Leslie, William D. and Kanis, John. (2018). Assessment of fracture risk. In In N. C. Harvey and C. Cooper (Ed.). Osteoporosis: A lifecourse epidemiology approach to skeletal health pp. 163 - 176 CRC Press. https://doi.org/10.1201/9781351234627
Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry
Leslie, William D., Shevroja, E., Johansson, Helena, McCloskey, Eugene, Harvey, Nicholas C., Kanis, John A. and Hans, Didier. (2018). Risk-equivalent T-score adjustment for using lumbar spine trabecular bone score (TBS): The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 751 - 758. https://doi.org/10.1007/s00198-018-4405-0
Pitfalls in the measurement of muscle mass: A need for a reference standard
Buckinx, Fanny, Landi, Francesco, Cesari, Matteo, Fielding, Roger A., Visser, Marjolein, Engelke, Klaus, Maggi, Stefania, Dennison, Elaine, Al-Daghri, Nasser M., Allepaerts, Sophie, Bauer, Jurgen, Bautmans, Ivan, Brandi, Maria Luisa, Bruyère, Olivier, Cederholm, Tommy, Cerreta, Francesca, Cherubini, Antonio, Cooper, Cyrus, Cruz-Jentoft, Alphonso, ... Kanis, John A.. (2018). Pitfalls in the measurement of muscle mass: A need for a reference standard. Journal of Cachexia, Sarcopenia and Muscle. 9(2), pp. 269 - 278. https://doi.org/10.1002/jcsm.12268
Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers
Johansson, Helena, Vala, C. H., Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene, Kanis, John, Harvey, Nicholas C., Ohlsson, Claes, Lohmander, L. S., Karrholm, J. and Mellstrom, D.. (2018). Low risk for hip fracture and high risk for hip arthroplasty due to osteoarthritis among Swedish farmers. Osteoporosis International. 29(3), pp. 741 - 749. https://doi.org/10.1007/s00198-017-4355-y
Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation
Rizzoli, Rene, Biver, Emmanuel, Bonjour, J. P., Coxam, V., Goltzman, D., Kanis, John, Lappe, J., Rejnmark, Lars, Sahni, S., Weaver, C., Weiler, H. and Reginster, J. Y.. (2018). Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation. Osteoporosis International. 29(9), pp. 1933 - 1948. https://doi.org/10.1007/s00198-018-4534-5
The prevalence of vertebral fractures is associated with reduced hip bone density and inferior peripheral appendicular volumetric bone density and structure in older women
Johansson, Lisa, Sundh, Daniel, Zoulakis, Michael, Rudäng, Robert, Darelid, Anna, Brisby, Helena, Nilsson, Anna G., Mellström, Dan and Lorentzon, Mattias. (2018). The prevalence of vertebral fractures is associated with reduced hip bone density and inferior peripheral appendicular volumetric bone density and structure in older women. Journal of Bone and Mineral Research. 33(2), pp. 250 - 260. https://doi.org/10.1002/jbmr.3297
A health economic simulation model for the clinical management of osteoporosis
Jonsson, E., Hansson-Hedblom, A., Ljunggren, Östen, Åkesson, K., Spångeus, A., Kanis, John and Borgström, F.. (2018). A health economic simulation model for the clinical management of osteoporosis. Osteoporosis International. 29(3), pp. 545 - 555. https://doi.org/10.1007/s00198-017-4325-4
Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population
Povoroznyuk, V. V., Grygorieva, Nataliia V., McCloskey, Eugene, Johansson, Helena and Kanis, John. (2018). Application of FRAX to determine the risk of osteoporotic fractures in the Ukrainian population. International Journal of Osteoporosis and Metabolic Disorders. 11(1), pp. 7 - 13. https://doi.org/10.3923/ijom.2018.7.13
Characteristics of recurrent fractures
Kanis, J. A., Johansson, H., Odén, A., Harvey, N. C., Gudnason, V., Sanders, K., Sigurdsson, G., Siggeirsdottir, K., Fitzpatrick, L. A., Borgström, F. and McCloskey, E. V.. (2018). Characteristics of recurrent fractures. Osteoporosis International. 29(8), pp. 1747-1757. https://doi.org/10.1007/s00198-018-4502-0
Understanding osteoporotic pain and its pharmacological treatment
Vellucci, R., Terenzi, R., Kanis, John, Kress, H. G., Mediati, R. D., Reginster, J. Y., Rizzoli, Rene and Brandi, Maria Luisa. (2018). Understanding osteoporotic pain and its pharmacological treatment. Osteoporosis International. 29(7), pp. 1477 - 1491. https://doi.org/10.1007/s00198-018-4476-y
Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women
Johansson, Lisa, Sundh, Daniel, Nilsson, Dan, Mellström, Dan and Lorentzon, Mattias. (2018). Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women. Osteoporosis International. 29(1), pp. 89 - 99. https://doi.org/10.1007/s00198-017-4296-5
Fracture risk after gastric bypass surgery: A retrospective cohort study
Axelsson, Kristian F., Werling, Malin, Eliasson, Björn, Szabo, Eva, Näslund, Ingmar, Wedel, Hans, Lundh, Dan and Lorentzon, Mattias. (2018). Fracture risk after gastric bypass surgery: A retrospective cohort study. Journal of Bone and Mineral Research. 33(12), pp. 2122 - 2131. https://doi.org/10.1002/jbmr.3553
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Jiang, Xia, O'Reilly, Paul F., Aschard, Hugues, Hsu, Yi-Hsiang, Richards, J. Brent, Dupuis, Josée, Ingelsson, Erik, Karasik, David, Pilz, Stefan, Berry, Diane, Kestenbaum, Bryan, Zheng, Jusheng, Luan, Jianan, Sofianopoulou, Eleni, Streeten, Elizabeth A., Albanes, Demetrius, Lutsey, Pamela L., Yao, Lu, Tang, Weihong, ... Lorentzon, Mattias. (2018). Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications. 9(1), p. 260. https://doi.org/10.1038/s41467-017-02662-2
Genetic determinants of circulating estrogen levels and evidence of a causal effect of estradiol on bone density in men
Eriksson, Anna L., Perry, John R. B., Coviello, Andreas D., Delgado, Graciela E., Ferrucci, Luigi, Hoffman, Andrew R., Huhtaniemi, Ilpo T., Ikram, M. Arfan, Karlsson, Magnus K., Kleber, Marcus E., Laughlin, Gail A., Liu, Yongmei, Lorentzon, Mattias, Lunetta, Kathryn L., Mellström, Dan, Murabito, Joanne M., Murray, Anna, Nethander, Maria, Nielson, Carrie M., ... Ohlsson, Claes. (2018). Genetic determinants of circulating estrogen levels and evidence of a causal effect of estradiol on bone density in men. The Journal of Clinical Endocrinology and Metabolism. 103(3), pp. 991 - 1004. https://doi.org/10.1210/jc.2017-02060
Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS)
Guirant, L., Carlos, Fernando, Curiel, D., Kanis, John A., Borgström, Frederick, Svedbom, Axel and Clark, Patricia. (2018). Health-related quality of life during the first year after a hip fracture: Results of the Mexican arm of the International Cost and Utility Related to Osteoporotic Fractures Study (MexICUROS). Osteoporosis International. 29(5), pp. 1147 - 1154. https://doi.org/10.1007/s00198-018-4389-9
Normal bone microstructure and density but worse physical function in older women treated with selective serotonin reuptake inhibitors, a cross-sectional population-based study
Larsson, Berit A. M., Mellström, Dan, Johansson, Lisa, Nilsson, Anna G., Lorentzon, Mattias and Sundh, Daniel. (2018). Normal bone microstructure and density but worse physical function in older women treated with selective serotonin reuptake inhibitors, a cross-sectional population-based study. Calcified Tissue International. 103(3), pp. 278 - 288. https://doi.org/10.1007/s00223-018-0427-z
Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture
Malafarina, Vincenzo, Reginster, J. Y., Cabrerizo, Sonia, Bruyère, Olivier, Kanis, John A., Martinez, J. Alfredo and Zulet, M. Angeles. (2018). Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture. Nutrients. 10(5), pp. 1 - 26. https://doi.org/10.3390/nu10050555
Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial
Shepstone, L., Lenaghan, E., Cooper, C., Clarke, Shane, Fong-Soe-Khioe, Rebekah, Fordham, R., Gittoes, Neil, Harvey, Ian, Harvey, Nicholas C., Heawood, A., Holland, R., Howe, A., Kanis, John, Marshall, Tarnya, O'Neill, T. W., Peters, T. J., Redmond, Niamh, Torgerson, David, Turner, David and McCloskey, Eugene. (2018). Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial. The Lancet. 391(10122), pp. 741 - 747. https://doi.org/10.1016/S0140-6736(17)32640-5
Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry
Leslie, William D., Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Schousboe, J. T., Ensrud, K. E., Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2018). Performance of FRAX in clinical practice according to sex and osteoporosis definitions: The Manitoba BMD registry. Osteoporosis International. 29(3), pp. 759 - 767. https://doi.org/10.1007/s00198-018-4415-y
The limited clinical utility of testosterone, estradiol, and sex hormone binding globulin measurements in the prediction of fracture risk and bone loss in older men
Orwoll, Eric S., Lapidus, Jodi, Wang, Patty Y., Vandenput, Liesbeth, Hoffman, Andrew, Fink, Howard A., Laughlin, Gail A., Nethander, Maria, Ljunggren, Östen, Kindmark, Andreas, Lorentzon, Mattias, Karlsson, Magnus K., Mellström, Dan, Kwok, Anthony, Khosla, Sundeep, Kwok, Timothy and Ohlsson, Claes. (2017). The limited clinical utility of testosterone, estradiol, and sex hormone binding globulin measurements in the prediction of fracture risk and bone loss in older men. Journal of Bone and Mineral Research. 32(3), pp. 633-640. https://doi.org/10.1002/jbmr.3021
Risk factors for low back pain and sciatica in elderly men--the MrOS Sweden study
Kherad, Mehrsa, Rosengren, Björn E., Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Mellström, Dan, Lorentzon, Mattias, Ljunggren, Östen and Karlsson, Magnus K.. (2017). Risk factors for low back pain and sciatica in elderly men--the MrOS Sweden study. Age and Ageing. 46(1), pp. 64 - 71. https://doi.org/10.1093/ageing/afw152
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Graff, Mariaelisa, Scott, Robert A., Justice, Anne E., Young, Kristin L., Feitosa, Mary F., Barata, Llilda, Winkler, Thomas W., Chu, Audrey Y., Mahajan, Anubha, Hadley, David, Xue, Luting, Workalemahu, Tsegaselassie, Heard-Costa, Nancy L., den Hoed, Marcel, Ahluwalia, Tarunveer S., Qi, bin Qi, Ngwa, Julius S., Renström, Frida, Quaye, Lydia, ... Lorentzon, Mattias. (2017). Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults. PLoS Genetics. 13(4), pp. 1 - 26. https://doi.org/10.1371/journal.pgen.1006528
Cortical bone area predicts incident fractures independently of areal bone mineral density in older men
Ohlsson, Claes, Sundh, Daniel, Wallerek, Andreas, Nilson, Martin, Karlsson, Magnus, Johansson, Helena, Mellstrom, Dan and Lorentzon, Mattias. (2017). Cortical bone area predicts incident fractures independently of areal bone mineral density in older men. The Journal of Clinical Endocrinology and Metabolism. 102(2), pp. 516 - 524. https://doi.org/10.1210/jc.2016-3177
Association between alendronate use and hip fracture risk in older patients using oral prednisolone
Axelsson, Kristian F., Nilsson, Anna G., Wedel, Hans, Lundh, Dan and Lorentzon, Mattias. (2017). Association between alendronate use and hip fracture risk in older patients using oral prednisolone. JAMA: Journal of the American Medical Association. 318(2), pp. 146 - 155. https://doi.org/10.1001/jama.2017.8040
Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo
Cianferotti, Luisella, Bertoldo, Francesco, Bischoff-Ferrari, Heike A., Bruyere, O., Cooper, Cyrus, Cutolo, Maurizio, Kanis, John A., Kaufman, Jean-Marc, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017). Vitamin D supplementation in the prevention and management of major chronic diseases not related to mineral homeostasis in adults: Research for evidence and a scientific statement from the European society for clinical and economic aspects of osteopo. Endocrine. 56(2), pp. 245 - 261. https://doi.org/10.1007/s12020-017-1290-9
Hip fracture risk and safety with alendronate treatment in the oldest-old
Axelsson, K. F., Wallander, M., Johansson, Helena, Lundh, D. and Lorentzon, Mattias. (2017). Hip fracture risk and safety with alendronate treatment in the oldest-old. Journal of Internal Medicine. 282(6), pp. 546 - 559. https://doi.org/10.1111/joim.12678
Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, O., Cooper, Cyrus, Kanis, John, Leeb, Burkhard F., Maheu, E., Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean P., Rizzoli, Rene and Reginster, Jean Yves. (2017). Erratum to: diacerein: benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 34(5), pp. 413 - 413. https://doi.org/10.1007/s40266-017-0457-7
Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort
Martineau, Patrick, Leslie, William, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Hans, Didier and Kanis, John. (2017). Clinical utility of using lumbar spine trabecular bone score to adjust fracture probability: the Manitoba BMD Cohort. Journal of Bone and Mineral Research. 32(7), pp. 1568 - 1574. https://doi.org/10.1002/jbmr.3124
Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS
Svedbom, A., Borgström, Fredrik, Hernlund, E., Ström, O., Alekna, V., Bianchi, Maria L., Clark, P., Curiel, M. D., Dimai, Hans P., Jürisson, M., Uusküla, A., Lember, M., Kallikorm, R., Lesnyak, Olga, McCloskey, Eugene, Ershova, Olga, Sanders, Kerrie, Silverman, S., Tamulaitiene, M., ... Kanis, John. (2017). Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS. Quality of Life Research. 27(3), pp. 707 - 716. https://doi.org/10.1007/s11136-017-1748-5
Type 2 diabetes and risk of hip fractures and non-skeletal fall injuries in the elderly: A study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO)
Wallander, Märit, Axelsson, Kristian F., Nilsson, Anna G., Lundh, Dan and Lorentzon, Mattias. (2017). Type 2 diabetes and risk of hip fractures and non-skeletal fall injuries in the elderly: A study from the Fractures and Fall Injuries in the Elderly Cohort (FRAILCO). Journal of Bone and Mineral Research. 32(3), pp. 449 - 460. https://doi.org/10.1002/jbmr.3002
Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity
McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Compston, Juliet E. and Kanis, J.. (2017). Access to fracture risk assessment by FRAX and linked National Osteoporosis Guideline Group (NOGG) guidance in the UK: an analysis of anonymous website activity. Osteoporosis International. 28(1), pp. 71 - 76. https://doi.org/10.1007/s00198-016-3696-2
Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, O., Cooper, Cyrus, Arden, Nigel, Branco, J., Brandi, Maria L., Herrero-Beaumont, G., Berenbaum, F., Dennison, Elaine M., Devogelaer, J. P., Hochberg, Marc, Kanis, John, Laslop, A., McAlindon, T., Reiter, Susanne, Richette, P., Rizzoli, Rene and Reginster, Jean Y.. (2017). Erratum to: can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 34(5), pp. 411 - 411. https://doi.org/10.1007/s40266-017-0456-8
Increased risk of hip fracture among spouses-evidence of a homogamy effect
Vala, C. H., Oden, Anders, Lorentzon, Mattias, Sundh, V., Johansson, Helena, Karlsson, Magnus, Rosengren, Björn E., Ohlsson, Claes, Johansson, B., Kanis, John and Mellström, Dan. (2017). Increased risk of hip fracture among spouses-evidence of a homogamy effect. Osteoporosis International. 28(1), pp. 95 - 102. https://doi.org/10.1007/s00198-016-3738-9
Total hip bone area affects fracture prediction with FRAX® in Canadian white women
Leslie, William D., Lix, Lisa, Majumdar, S. R., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017). Total hip bone area affects fracture prediction with FRAX® in Canadian white women. The Journal of Clinical Endocrinology and Metabolism. 102(11), pp. 4242 - 4249. https://doi.org/10.1210/jc.2017-01327
International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates
Diez-Perez, Aldolfo, Naylor, K. E., Abrahamsen, Bo, Agnusdei, D., Brandi, Maria L., Cooper, Cyrus, Dennison, Elaine M., Eriksen, E. F., Gold, D. T., Guañabens, N., Hadji, P., Hiligsmann, Mickaël, Horne, R., Josse, R. G., Kanis, John, Obermayer-Pietsch, Barbara, Prieto-Alhambra, D., Reginster, Jean Y., Rizzoli, Rene, ... Eastell, Richard. (2017). International osteoporosis foundation and European calcified tissue society working group. Recommendations for the screening of adherence to oral bisphosphonates. Osteoporosis International. 28(3), pp. 767 - 774. https://doi.org/10.1007/s00198-017-3906-6
Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate
Lesnyak, Olga, Sahakyan, S., Zakroyeva, A., Bilezikian, John P., Hutchings, N., Babalyan, V., Galstyan, R., Lebedev, A., Johansson, Helena, Harvey, Nicholas C., McCloskey, Eugene and Kanis, John. (2017). Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate. Archives of Osteoporosis. 12(98), pp. 1 - 9. https://doi.org/10.1007/s11657-017-0392-6
Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS
Svedbom, A., Borgstom, F., Hernlund, E., Strom, Oskar, Alekna, V., Bianchi, Maria L., Clark, Patricia M., Curiel, M. D., Dimai, Hans P., Jurisson, Mikk, Kallikorm, R., Lember, M., Lesnyak, Olga, McCloskey, Eugene, Sanders, Kerry M., Silverman, S., Solodovnikov, A., Tamulaitiene, M., Thomas, T., ... Kanis, John. (2017). Quality of life for up to 18 months after low-energy hip, vertebral, and distal forearm fractures - results from the ICUROS. Osteoporosis International. 29(3), pp. 557 - 566. https://doi.org/10.1007/s00198-017-4317-4
FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry
Leslie, William, Majumdar, S. R., Morin, Suzanne N., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2017). FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry. Osteoporosis International. 28(9), pp. 2557 - 2564. https://doi.org/10.1007/s00198-017-4091-3
Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG
Hadji, P., Aapro, Matti S., Body, Jean J., Gnant, Michael, Brandi, Maria L., Reginster, Jean Y., Zillikens, M. C., Glüer, C. C., de Villiers, T., Baber, Rod, Roodman, G. David, Cooper, Cyrus, Langdahl, Bente Lomholt, Palacios, Santiago, Kanis, John, Al-Daghri, Nasser M., Nogues, Xavier, Eriksen, Erik F., Kurth, Andreas, ... Coleman, Robert E.. (2017). Management of aromatase inhibitor-associated bone loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG. Journal of Bone Oncology. 7, pp. 1 - 12. https://doi.org/10.1016/j.jbo.2017.03.001
Bone traits seem to develop also during the third decade in life—normative cross-sectional data on 1083 men aged 18–28 years
Lindgren, Erik, Karlsson, Magnus K., Lorentzon, Mattias and Rosengren, Björn E.. (2017). Bone traits seem to develop also during the third decade in life—normative cross-sectional data on 1083 men aged 18–28 years. Journal of Clinical Densitometry. 20(1), pp. 32 - 43. https://doi.org/10.1016/j.jocd.2016.07.002
Imminent risk of fracture after fracture
Johansson, H., Siggeirsdóttir, K., Harvey, N. C., Odén, A., Gudnason, V., McCloskey, E., Sigurdsson, G. and Kanis, J. A.. (2017). Imminent risk of fracture after fracture. Osteoporosis International. 28(3), pp. 775-780. https://doi.org/10.1007/s00198-016-3868-0
Clinical settings in knee osteoarthritis: Pathophysiology guides treatment
Herrero-Beaumont, Gabriel, Roman-Blas, Jorge A., Bruyère, Olivier, Cooper, Cyrus, Kanis, John, Maggi, S., Rizzoli, René and Reginster, Jean-Yves. (2017). Clinical settings in knee osteoarthritis: Pathophysiology guides treatment. Maturitas. 96, pp. 54 - 57. https://doi.org/10.1016/j.maturitas.2016.11.013
Epidemiology of hip fracture and the development of FRAX in Ukraine
Povoroznyuk, V. V., Grygorieva, N. V., Kanis, John, McCloskey, Eugene, Johansson, Helena, Harvey, Nicholas C., Korzh, M. O., Strafun, S. S., Vaida, V. M., Klymovytsky, F. V., Vlasenko, R. R. and Forosenko, V. S.. (2017). Epidemiology of hip fracture and the development of FRAX in Ukraine. Archives of Osteoporosis. 12(1), pp. 1 - 6. https://doi.org/10.1007/s11657-017-0343-2
Low testosterone, but not estradiol, is associated with incident falls in older men: The international MrOS study
Vandenput, Liesbeth, Mellström, Dan, Laughlin, Gail A., Cawthon, Peggy M., Cauley, Jane A., Hoffman, Andrew R., Karlsson, Magnus K., Rosengren, Björn E., Ljunggren, Östen, Nethander, Maria, Eriksson, Anna L., Lorentzon, Mattias, Leung, Jason, Kwok, Timothy, Orwoll, Eric S. and Ohlsson, Claes. (2017). Low testosterone, but not estradiol, is associated with incident falls in older men: The international MrOS study. Journal of Bone and Mineral Research. 32(6), pp. 1174 - 1181. https://doi.org/10.1002/jbmr.3088
Overview of fracture prediction tools
Kanis, John, A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, McCloskey, Eugene V. and Leslie, William D.. (2017). Overview of fracture prediction tools. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 444-450. https://doi.org/10.1016/j.jocd.2017.06.013
Increased cortical porosity in women with hip fracture
Sundh, Daniel, Nilsson, A. G., Nilsson, Martin, Johansson, L., Mellström, Dan and Lorentzon, Mattias. (2017). Increased cortical porosity in women with hip fracture. Journal of Internal Medicine. 281(5), pp. 496 - 506. https://doi.org/10.1111/joim.12587
FRAX- vs. T-score-based intervention thresholds for osteoporosis
Johansson, Helena, Azizieh, F., al Ali, N., Alessa, T., Harvey, Nicholas C., McCloskey, Eugene and Kanis, John A.. (2017). FRAX- vs. T-score-based intervention thresholds for osteoporosis. Osteoporosis International. 28(11), pp. 3099 - 3105. https://doi.org/10.1007/s00198-017-4160-7
Association of mental disorders and related medication use with risk for major osteoporotic fractures
Bolton, James M., Morin, Suzanne N., Majumdar, S. R., Sareen, Jitender, Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Leslie, William. (2017). Association of mental disorders and related medication use with risk for major osteoporotic fractures. JAMA Psychiatry. 74(6), pp. 641 - 648. https://doi.org/10.1001/jamapsychiatry.2017.0449
The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability : A post hoc analysis of the ACTIVE study
McCloskey, Eugene V., Johansson, Helena, Oden, Anders, Harvey, Nicholas C., Jiang, Hai, Modin, Sara, Fitzpatrick, Lorraine and Kanis, John A.. (2017). The effect of abaloparatide-SC on fracture risk is independent of baseline FRAX fracture probability : A post hoc analysis of the ACTIVE study. Journal of Bone and Mineral Research. 32(8), pp. 1625-1631. https://doi.org/10.1002/jbmr.3163
Low serum iron is associated with high serum intact FGF23 in elderly men: The Swedish MrOS study
Lewerin, Catharina, Ljunggren, Östen, Nilsson-Ehle, Herman, Karlsson, Magnus K., Herlitz, Hans, Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2017). Low serum iron is associated with high serum intact FGF23 in elderly men: The Swedish MrOS study. Bone. 98, pp. 1 - 8. https://doi.org/10.1016/j.bone.2017.02.005
Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting
Kanis, John, Cooper, Cyrus, Rizzoli, Rene, Abrahamsen, Bo, Al-Daghri, N. M., Brandi, Maria L., Cannata, J. B., Cortet, B., Dimai, Hans P., Ferrari, S., Hadji, P., Harvey, Nicholas C., Kraenzlin, M., Kurth, Andreas, McCloskey, Eugene, Minisola, Salvatore, Thomas, T. and Reginster, Jean Y.. (2017). Erratum to: identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting. Osteoporosis International. 28(11), pp. 3285 - 3286. https://doi.org/10.1007/s00198-017-4161-6
Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review
Beaudart, Charlotte, Dawson, A., Shaw, S. C., Harvey, Nicholas C., Kanis, John, Binkley, Neil, Reginster, Jean Yves, Chapurlat, R., Chan, D. C., Bruyère, O., Rizzoli, Rene, Cooper, Cyrus and Dennison, Elaine M.. (2017). Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporosis International. 28(6), pp. 1817 - 1833. https://doi.org/10.1007/s00198-017-3980-9
Low-frequency synonymous coding variation in CYP2R1 has large effects on vitamin d levels and risk of multiple sclerosis
Manousaki, Despoina, Dudding, Tom, Haworth, Simon, Hsu, Yi-Hsiang, Liu, Chiang-Ti, Medina-Gómez, Carolina, Voortman, Trudy, van der Velde, Nathalie, Melhus, Håkan, Robinson-Cohen, Cassianne, Cousminer, Diana L., Nethander, Maria, Vandenput, Liesbeth, Noordam, Raymond, Forgetta, Vincenzo, Greenwood, Celia M. T., Biggs, Mary L., Psaty, Bruce M., Rotter, Jerome I., ... Richards, J. Brent. (2017). Low-frequency synonymous coding variation in CYP2R1 has large effects on vitamin d levels and risk of multiple sclerosis. American Journal of Human Genetics. 101(2), pp. 227 - 238. https://doi.org/10.1016/j.ajhg.2017.06.014
FRAX update
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Odén, Anders, Leslie, William D. and McCloskey, Eugene V.. (2017). FRAX update. Journal of Clinical Densitometry: Assessment & Management of Musculoskeletal Health. 20(3), pp. 360 - 367. https://doi.org/10.1016/j.jocd.2017.06.022
Type 2 diabetes mellitus is associated with better bone microarchitecture but lower bone material strength and poorer physical function in elderly women: A population-based study
Nilsson, Anna G., Sundh, Daniel, Johansson, Lisa, Nilsson, Martin, Mellström, Dan, Rudäng, Robert, Zoulakis, Michail, Wallander, Märit, Darelid, Anna and Lorentzon, Mattias. (2017). Type 2 diabetes mellitus is associated with better bone microarchitecture but lower bone material strength and poorer physical function in elderly women: A population-based study. Journal of Bone and Mineral Research. 32(5), pp. 1062 - 1071. https://doi.org/10.1002/jbmr.3057
Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil
Silva, Dalisbor M.W., Borba, Victoria Z.C. and Kanis, John. (2017). Evaluation of clinical risk factors for osteoporosis and applicability of the FRAX tool in Joinville City, southern Brazil. Archives of Osteoporosis. 12(111), pp. 1 - 8. https://doi.org/10.1007/s11657-017-0405-5
Bone mass development from childhood into young adulthood in patients with childhood-onset inflammatory bowel disease
Sigurdsson, Gudmundur Vignir, Schmidt, Susanne, Mellström, Dan, Ohlsson, Claes, Kindblom, Jenny M., Lorentzon, Mattias and Saalman, Robert. (2017). Bone mass development from childhood into young adulthood in patients with childhood-onset inflammatory bowel disease. Inflammatory Bowel Diseases. 23(12), pp. 2215 - 2226. https://doi.org/10.1097/MIB.0000000000001277
Genetic variants associated with circulating parathyroid hormone
Robinson-Cohen, Cassianne, Lutsey, Pamela L., Kleber, Marcus E., Nielson, Carrie M., Mitchell, Braxton D., Bis, Joshua C., Eny, Karen M., Portas, Laura, Eriksson, Joel, Lorentzon, Mattias, Koller, Daniel L., Milaneschi, Yuri, Teumer, Alexander, Pilz, Stefan, Nethander, Maria, Selvin, Elizabeth, Tang, Weihong, Weng, Lu-Chen, Wong, Hoi Suen, ... Kestenbaum, Bryan. (2017). Genetic variants associated with circulating parathyroid hormone. Journal of the American Society of Nephrology. 28(5), pp. 1553 - 1565. https://doi.org/10.1681/ASN.2016010069
The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF)
Harvey, Nicholas C., Biver, Emmanuel, Kaufman, J,, Bauer, Jürgen M., Branco, J., Brandi, Maria Luisa, Bruyère, O., Coxam, V., Cruz-Jentoft, Alfonso J., Czerwinski, E., Dimai, Hans P., Fardellone, P., Landi, Francesco, Reginster, Jean Yves, Dawson-Hughes, Bess, Kanis, John, Rizzoli, Rene and Cooper, Cyrus. (2017). The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF). Osteoporosis International. 28(2), pp. 447 - 462. https://doi.org/10.1007/s00198-016-3773-6
Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis
Eriksson, Joel, Haring, Robin, Grarup, Niels, Vandenput, Liesbeth, Wallaschofski, Henri, Lorentzen, Erik, Hansen, Torben, Mellström, Dan, Pedersen, Oluf, Nauck, Matthias, Lorentzon, Mattias, Husemoen, Lise Lotte Nystrup, Völzke, Henry, Karlsson, Magnus, Baumeister, Sebastian E., Linneberg, Allan and Ohlsson, Claes. (2017). Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis. PLoS ONE. 12(4), pp. 1 - 15. https://doi.org/10.1371/journal.pone.0176277
UK clinical guideline for the prevention and treatment of osteoporosis
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Gittoes, Neil, Gregson, C., Harvey, Nicholas C., Hope, S., Kanis, John, McCloskey, Eugene, Poole, Kenneth E.S., Reid, David M., Selby, P., Thompson, F., Thurston, A. and Vine, N.. (2017). UK clinical guideline for the prevention and treatment of osteoporosis. Archives of Osteoporosis. 12(43), pp. 1 - 24. https://doi.org/10.1007/s11657-017-0324-5
Romosozumab or alendronate for fracture prevention in women with osteoporosis
Saag, Kenneth G., Petersen, Jeffrey, Brandi, Maria Luisa, Karaplis, Andrew C., Lorentzon, Mattias, Thomas, Thierry A., Maddox, Judy, Fan, Michelle, Meisner, Paul D. and Grauer, Andreas. (2017). Romosozumab or alendronate for fracture prevention in women with osteoporosis. New England Journal of Medicine. 377(15), pp. 1417 - 1427. https://doi.org/10.1056/NEJMoa1708322
The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation
Cianferotti, Luisella, Bertoldo, Francesco, Carini, Marco, Kanis, John A., Lapini, Alberto, Longo, Nicola, Martorana, Giuseppe, Mirone, Vincenzo, Reginster, Jean-Yves, Rizzoli, Rene and Brandi, Maria Luisa. (2017). The prevention of fragility fractures in patients with non-metastatic prostate cancer: A position statement by the international osteoporosis foundation. Oncotarget. 8(43), pp. 75646 - 75663. https://doi.org/10.18632/oncotarget.17980
FRAX-based intervention and assessment thresholds in seven Latin American countries
Clark, P., Denova-Gutiérrez, E., Zerbini, Cristiano, Sanchez, A., Messina, O. D., Jaller, J. J., Campusano, C., Orces, C. H., Riera, G., Johansson, Helena and Kanis, John. (2017). FRAX-based intervention and assessment thresholds in seven Latin American countries. Osteoporosis International. 29(3), pp. 707 - 715. https://doi.org/10.1007/s00198-017-4341-4
Low serum DHEAS predicts increased fracture risk in older men: The MrOS Sweden study
Ohlsson, Claes, Nethander, Maria, Kindmark, Andreas, Ljunggren, Östen, Lorentzon, Mattias, Rosengren, Björn E., Karlsson, Magnus K., Mellström, Dan and Vandenput, Liesbeth. (2017). Low serum DHEAS predicts increased fracture risk in older men: The MrOS Sweden study. Journal of Bone and Mineral Research. 32(8), pp. 1607 - 1614. https://doi.org/10.1002/jbmr.3123
Current physical activity is independently associated with cortical bone size and bone strength in elderly Swedish women
Nilsson, Martin, Sundh, Daniel, Mellström, Dan and Lorentzon, Mattias. (2017). Current physical activity is independently associated with cortical bone size and bone strength in elderly Swedish women. Journal of Bone and Mineral Research. 32(3), pp. 473 - 485. https://doi.org/10.1002/jbmr.3006
Which measuring site in ankylosing spondylitis is best to detect bone loss and what predicts the decline: results from a 5-year prospective study
Deminger, Anna, Klingberg, Eva, Lorentzon, Mattias, Geijer, Mats, Göthlin, Jan, Hedberg, Martin, Rehnberg, Eva, Carlsten, Hans, Jacobsson, Lennart T. and Forsblad-d'Elia, Helena. (2017). Which measuring site in ankylosing spondylitis is best to detect bone loss and what predicts the decline: results from a 5-year prospective study. Arthritis Research and Therapy. 19(1), pp. 1 - 12. https://doi.org/10.1186/s13075-017-1480-0
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, Anne E., Winkler, Thomas W., Feitosa, Mary F., Graff, Misa, Fisher, Virginia A., Young, Kristin L., Barata, Llilda, Deng, Xuan, Czajkowski, Jacek, Hadley, David, Ngwa, Julius S., Ahluwalia, Tarunveer S., Chu, Audrey Y., Heard-Costa, Nancy L., Lim, Elise, Perez, Jeremiah, Eicher, John D., Kutalik, Zoltán, Xue, Luting, ... Lorentzon, Mattias. (2017). Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications. 8(1), pp. 1 - 19. https://doi.org/10.1038/ncomms14977
Characteristics of prevalent vertebral fractures predict new fractures in elderly men
Karlsson, Magnus K., Kherad, Mehrsa, Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias, Mellström, Dan and Rosengren, Björn E.. (2016). Characteristics of prevalent vertebral fractures predict new fractures in elderly men. Journal of Bone and Joint Surgery: American Volume. 98(5), pp. 379 - 385. https://doi.org/10.2106/JBJS.15.00328
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, Janina S., Jeff, Janina, Chu, Audrey Y., Bragg-Gresham, Jennifer L., van Dongen, Jenny, Huffman, Jennifer E., Ahluwalia, Tarunveer S., Cadby, Gemma, Eklund, Niina, Eriksson, Joel, Esko, Tõnu, Feitosa, Mary F., Goel, Anuj, Gorski, Mathias, Hayward, Caroline, Heard-Costa, Nancy L., Jackson, Anne U., Jokinen, Eero, Kanoni, Stavroula, ... Loos, Ruth J. F.. (2016). A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 7(1), pp. 1 - 11. https://doi.org/10.1038/ncomms13357
Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John Anthony. (2016). Adjusting hip fracture probability in men and women using hip axis length: The Manitoba Bone Density Database. Journal of Clinical Densitometry. 19(3), pp. 326 - 331. https://doi.org/10.1016/j.jocd.2015.07.004
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Teumer, Alexander, Qi, bin Qi, Nethander, Maria, Aschard, Hugues, Bandinelli, Stefania, Beekman, Marian, Berndt, Sonja I., Bidlingmaier, Martin, Broer, Linda, Cappola, Anne, Ceda, Gian Paolo, Chanock, Stephen J., Chen, Ming-Huei, Chen, Tai C., Chen, Yii-Der, Chung, Jonathan, Del Greco Miglianico, Fabiola, Eriksson, Joel, Ferrucci, Luigi, ... Lorentzon, Mattias. (2016). Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 15(5), pp. 811 - 824. https://doi.org/10.1111/acel.12490
Determinants of microstructural, dimensional and bone mineral changes postpartum in Swedish women
Brembeck, Peter, Winkvist, Anna, Ohlsson, Claes, Lorentzon, Mattias and Augustin, Hanna. (2016). Determinants of microstructural, dimensional and bone mineral changes postpartum in Swedish women. The British Journal of Nutrition. 116(10), pp. 1736 - 1744. https://doi.org/10.1017/S0007114516003998
A systematic review of intervention thresholds based on FRAX : A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation
Kanis, John A., Harvey, Nicholas C., Cooper, Cyrus, Johansson, Helena, Odén, Anders, McCloskey, Eugene V. and The Advisory Board of the National Osteoporosis Guideline Group. (2016). A systematic review of intervention thresholds based on FRAX : A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Archives of Osteoporosis. 11, p. Article 25. https://doi.org/10.1007/s11657-016-0278-z
FRAX predicts incident falls in elderly men: findings from MrOs Sweden
Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Karlsson, Magnus, Rosengren, Björn E., Ljunggren, Östen, Cooper, Cyrus, McCloskey, Eugene V., Kanis, John A., Ohlsson, C. and Mellström, Dan. (2016). FRAX predicts incident falls in elderly men: findings from MrOs Sweden. Osteoporosis International. 27(1), pp. 267 - 274. https://doi.org/10.1007/s00198-015-3295-7
Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey
Bruyère, O., Beaudart, Charlotte, Reginster, Jean Yves, Buckinx, F., Schoene, D., Hirani, V., Cooper, Cyrus, Kanis, John, Rizzoli, Rene, McCloskey, Eugene, Cederholm, T., Cruz-Jentoft, Alfonso J. and Freiberger, E.. (2016). Assessment of muscle mass, muscle strength and physical performance in clinical practice: An international survey. European Geriatric Medicine. 7(3), pp. 243 - 246. https://doi.org/10.1016/j.eurger.2015.12.009
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, Rene, Cortet, Bernard, Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo, Alvarez, M. N., ... Treml, J.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. European Geriatric Medicine. 7(6), pp. 519 - 525. https://doi.org/10.1016/j.eurger.2016.04.012
Fall risk assessment predicts fall-related injury, hip fracture, and head injury in older adults
Nilsson, , Eriksson, Joel, Larsson, Berit A. M., Odén, Anders, Johansson, Helena and Lorentzon, Mattias. (2016). Fall risk assessment predicts fall-related injury, hip fracture, and head injury in older adults. Journal of the American Geriatrics Society. 64(11), pp. 2242 - 2250. https://doi.org/10.1111/jgs.14439
Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Josse, R. G., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016). Direct comparison of FRAX(R) and a simplified fracture risk assessment tool in routine clinical practice: A registry-based cohort study. Osteoporosis International. 27(9), pp. 2689 - 2695. https://doi.org/10.1007/s00198-016-3613-8
Bone material strength is associated with areal BMD but not with prevalent fractures in older women
Rudäng, R., Zoulakis, M., Sundh, D., Brisby, H., Diez-Perez, Aldolfo, Johansson, L., Mellström, Dan, Darelid, A. and Lorentzon, Mattias. (2016). Bone material strength is associated with areal BMD but not with prevalent fractures in older women. Osteoporosis International. 27(4), pp. 1585 - 1592. https://doi.org/10.1007/s00198-015-3419-0
A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, Nathalie, Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John, Reginster, Jean Y., Rizzoli, Rene, Cortet, B., Barbagallo, M., Dreinhöfer, K., Vellas, B., Maggi, S., Strandberg, Timo E., Alvarez, M. N., ... Macijauskien, J. (2016). A comprehensive fracture prevention strategy in older adults: the European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
FRAX updates 2016
McCloskey, Eugene V., Harvey, Nicholas C., Johansson, Helena and Kanis, John A.. (2016). FRAX updates 2016. Current Opinion in Rheumatology. 28(4), pp. 433 - 441. https://doi.org/10.1097/BOR.0000000000000304
Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO
Pavelka, Karel, Bruyère, Olivier, Cooper, Cyrus, Kanis, John A., Leeb, Burkhard F., Maheu, Emmanuel, Martel-Pelletier, Johanne, Monfort, Jordi, Pelletier, Jean-Pierre, Rizzoli, Rene and Reginster, Jean-Yves. (2016). Diacerein: Benefits, risks and place in the management of osteoarthritis. An opinion-based report from the ESCEO. Drugs and Aging. 33(2), pp. 75 - 85. https://doi.org/10.1007/s40266-016-0347-4
High serum SHBG predicts incident vertebral fractures in elderly men
Vandenput, Liesbeth, Mellström, Dan, Kindmark, Andreas, Johansson, Helena, Lorentzon, Mattias, Leung, Jason, Redlund-Johnell, Inga, Rosengren, Björn E., Karlsson, Magnus K., Wang, Yi-Xiang, Kwok, Timothy and Ohlsson, Claes. (2016). High serum SHBG predicts incident vertebral fractures in elderly men. Journal of Bone and Mineral Research. 31(3), pp. 683 - 689. https://doi.org/10.1002/jbmr.2718
Quality of life, resource use, and costs related to hip fracture in Estonia
Jurisson, Mikk, Pisarev, Heti, Kanis, John, Borgstrom, F., Svedbom, A., Kallikorm, R., Lember, M. and Uusküla, A.. (2016). Quality of life, resource use, and costs related to hip fracture in Estonia. Osteoporosis International. 27(8), pp. 2555 - 2566. https://doi.org/10.1007/s00198-016-3544-4
Effectiveness of a minimal resource fracture liaison service
Axelsson, K. F., Jacobsson, R., Lund, D. and Lorentzon, Mattias. (2016). Effectiveness of a minimal resource fracture liaison service. Osteoporosis International. 27(11), pp. 3165 - 3175. https://doi.org/10.1007/s00198-016-3643-2
High plasma osteocalcin is associated with low blood haemoglobin in elderly men: The MrOS Sweden Study
Lewerin, C., Johansson, Helena, Karlsson, Magnus K., Lorentzon, Mattias, Lerner, Ulf H., Kindblom, J. M., Ohlsson, Claes, Smith, Ulf and Mellström, Dan. (2016). High plasma osteocalcin is associated with low blood haemoglobin in elderly men: The MrOS Sweden Study. Journal of Internal Medicine. 280(4), pp. 398 - 406. https://doi.org/10.1111/joim.12505
Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort
Majumdar, Sumit R., Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2016). Longer duration of diabetes strongly impacts fracture risk assessment: The Manitoba BMD cohort. The Journal of Clinical Endocrinology and Metabolism. 101(11), pp. 4489 - 4496. https://doi.org/10.1210/jc.2016-2569
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Aging Clinical and Experimental Research. 28(4), pp. 797 - 803. https://doi.org/10.1007/s40520-016-0588-4
A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement
Blain, H., Masud, Tahir, Dargent-Molina, P., Martin, F. C., Rosendahl, E., van der Velde, N., Bousquet, J., Benetos, A., Cooper, Cyrus, Kanis, John A., Reginster, Jean Yves, Rizzoli, R., Cortet, B., Barbagallo, M., Dreinhöfer, K. E., Vellas, B., Maggi, S. and Strandberg, T.. (2016). A comprehensive fracture prevention strategy in older adults: The European Union Geriatric Medicine Society (EUGMS) statement. Journal of Nutrition, Health and Aging. 20(6), pp. 647 - 652. https://doi.org/10.1007/s12603-016-0741-y
Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal
Marques, Andréa, Lourenço, Óscar, Ortsäter, Gustaf, Borgstrom, Fredrik, Kanis, John A. and da Silva, José António P.. (2016). Cost-effectiveness of intervention thresholds for the treatment of osteoporosis based on FRAX(R) in Portugal. Calcified Tissue International. 99(2), pp. 131 - 141. https://doi.org/10.1007/s00223-016-0132-8
Low serum vitamin D is associated with higher cortical porosity in elderly men
Sundh, D., Mellström, Dan, Ljunggren, Östen, Karlsson, Magnus K., Ohlsson, Claes, Nilsson, M., Nilsson, A. G. and Lorentzon, Mattias. (2016). Low serum vitamin D is associated with higher cortical porosity in elderly men. Journal of Internal Medicine. 280(5), pp. 496 - 508. https://doi.org/10.1111/joim.12514
Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture
Ferrari, S., Reginster, Jean Yves, Brandi, Maria Luisa, Kanis, John A., Devogelaer, J. P., Kaufman, J. M., Féron, J. M., Kurth, Andreas and Rizzoli, René. (2016). Unmet needs and current and future approaches for osteoporotic patients at high risk of hip fracture. Archives of Osteoporosis. 11(1), pp. 1 - 12. https://doi.org/10.1007/s11657-016-0292-1
Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O
Cooper, Cyrus, Bardin, Thomas, Brandi, M. L., Cacoub, Patrice, Caminis, John, Civitelli, Roberto, Cutolo, Maurizio, Dere, Willard, Devogelaer, Jean-Pierre, Diez-Perez, Adolfo, Einhorn, Thomas A., Emonts, Patrick, Ethgen, Olivier, Kanis, John A., Kaufman, Jean-Marc, Kvien, Tore K., Lems, Willem F., McCloskey, Eugene, Miossec, Pierre, ... Reginster, Jean-Yves. (2016). Balancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and O. Aging Clinical and Experimental Research. 28(1), pp. 1 - 16. https://doi.org/10.1007/s40520-015-0522-1
SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture
Kanis, John A., Compston, Juliet, Cooper, Cyrus, Harvey, Nicholas C., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2016). SIGN Guidelines for Scotland: BMD Versus FRAX Versus QFracture. Calcified Tissue International. 98(5), pp. 417 - 425. https://doi.org/10.1007/s00223-015-0092-4
A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Maheu, Emmanuel, Rannou, François, Branco, Jaime, Brandi, Maria Luisa, Kanis, John A., Altman, Roy D., Hochberg, Marc C., Martel-Pelletier, Johanne and Reginster, Jean-Yves. (2016). A consensus statement on the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) algorithm for the management of knee osteoarthritis-From evidence-based medicine to the real-life setting. Seminars in Arthritis and Rheumatism. 45(4), pp. S3 - S11. https://doi.org/10.1016/j.semarthrit.2015.11.010
A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX
McCloskey, Eugene, Oden, Anders, Harvey, Nicholas C., Leslie, William, Hans, D., Johansson, Helena, Barkmann, Reinhard, Boutroy, Stephanie, Brown, J. P., Chapurlat, Roland D., Elders, Petra J. M., Fujita, Yuki, Glüer, Claus C., Goltzman, David, Iki, Masayuki, Karlsson, M. K., Kindmark, Andreas, Kotowicz, Mark, Kurumatani, Norio, ... Kanis, John A.. (2016). A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX. Journal of Bone and Mineral Research. 31(5), pp. 940 - 948. https://doi.org/10.1002/jbmr.2734
Sarcopenia in daily practice: Assessment and management
Beaudart, Charlotte, McCloskey, Eugene, Bruyère, Olivier, Cesari, Matteo, Rolland, Yves, Rizzoli, Rene, de Carvalho, Islène Araujo, Thiyagarajan, Jotheeswaran Amuthavalli, Bautmans, Ivan, Bertière, Marie-Claude, Brandi, Maria Luisa, Al-Daghri, Nasser M., Burlet, Nansa, Cavalier, Etienne, Cerreta, Francesca, Cherubini, Antonio, Fielding, Roger, Gielen, Evelien, Landi, Francesco, ... Cooper, Cyrus. (2016). Sarcopenia in daily practice: Assessment and management. BMC Geriatrics. 16(170), pp. 1 - 10. https://doi.org/10.1186/s12877-016-0349-4
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, Tuomas O., Martin Carli, Jayne F., Skowronski, Alicja A., Sun, Qi, Kriebel, Jennifer, Feitosa, Mary F., Hedman, Åsa K., Drong, Alexander W., Hayes, James E., Zhao, Jinghua H., Pers, Tune H., Schick, Ursula M., Grarup, Niels, Kutalik, Zoltán, Trompet, Stella, Mangino, Massimo, Kristiansson, Kati, Beekman, Marian, Lyytikäinen, Leo-Pekka, ... Lorentzon, Mattias. (2016). Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications. 7(1), pp. 1 - 14. https://doi.org/10.1038/ncomms10494
Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia
Reginster, Jean Yves, Cooper, Cyrus, Rizzoli, Rene, Kanis, John A., Appelboom, Geoff, Bautmans, Ivan, Bischoff-Ferrari, Heike A., Boers, Maarten, Brandi, Maria Luisa, Bruyère, Olivier, Cherubini, Antonio, Flamion, Bruno, Fielding, Roger A., Gasparik, Andrea Ildiko, Van Loon, Lucas, McCloskey, Eugene, Mitlak, Bruce, Pilotto, Alberto, Reiter-Niesert, Suzanne, ... Cruz-Jentoft, Alfonso J.. (2016). Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clinical and Experimental Research. https://doi.org/10.1007/s40520-015-0517-y
A high amount of local adipose tissue Is associated with high cortical porosity and low bone material strength in older women
Sundh, Daniel, Rudäng, Robert, Zoulakis, Michail, Nilsson, Anna G., Darelid, Anna and Lorentzon, Mattias. (2016). A high amount of local adipose tissue Is associated with high cortical porosity and low bone material strength in older women. Journal of Bone and Mineral Research. 31(4), pp. 749 - 757. https://doi.org/10.1002/jbmr.2747
Low-level cadmium exposure is associated with decreased bone mineral density and increased risk of incident fractures in elderly men: The MrOS Sweden study
Wallin, Maria, Barregard, Lars, Sallsten, Gerd, Lundh, Thomas, Karlsson, Magnus K., Lorentzon, Mattias, Ohlsson, Claes and Mellström, Dan. (2016). Low-level cadmium exposure is associated with decreased bone mineral density and increased risk of incident fractures in elderly men: The MrOS Sweden study. Journal of Bone and Mineral Research. 31(4), pp. 732 - 741. https://doi.org/10.1002/jbmr.2743
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study
Winkler, T.W., Justice, A.E., Graff, M., Barata, Llilda, Feitosa, M.F., Chu, Su, Czajkowski, Jacek, Esko, T., Fall, T., Kilpeläinen, T.O., Lu, Yingchang, Mägi, R., Mihailov, E., Lorentzon, Karl Mattias, Vandenput, Liesbeth and et. al.. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study. PLoS Genetics. 11(10), pp. 1-42. https://doi.org/10.1371/journal.pgen.1005378
Can we treat to target in osteoporosis?
McCloskey, Eugene, Harvey, Nicholas C. and Kanis, John. (2015). Can we treat to target in osteoporosis? International Journal of Clinical Rheumatology. 10(1), pp. 1 - 4. https://doi.org/10.2217/ijr.14.59
Burden of high fracture probability worldwide: Secular increases 2010--2040
Oden, Anders, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C. and Johansson, Helena. (2015). Burden of high fracture probability worldwide: Secular increases 2010--2040. Osteoporosis International. 26(9), pp. 2243 - 2248. https://doi.org/10.1007/s00198-015-3154-6
Osteoporosis: The evolution of a diagnosis
Lorentzon, Mattias and Cummings, Steven R.. (2015). Osteoporosis: The evolution of a diagnosis. Journal of Internal Medicine. 277(6), pp. 650 - 661. https://doi.org/10.1111/joim.12369
Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis
Reginster, Jean Yves, Cooper, Cyrus, Hochberg, Marc, Pelletier, Jean Pierre, Rizzoli, R, Kanis, John A., Abadie, Eric, Maheu, E., Brandi, Maria Luisa, Devogelaer, J. P., Branco, J., Herrero-Beaumont, G., D'Hooghe, Pieter and Bruyère, O.. (2015). Comments on the discordant recommendations for the use of symptomatic slow-acting drugs in knee osteoarthritis. Current Medical Research and Opinion. 31(5), pp. 1041 - 1045. https://doi.org/10.1185/03007995.2015.1027183
Intervention thresholds and the diagnosis of osteoporosis
Kanis, John A., McCloskey, Eugene, Harvey, Nicholas C., Johansson, Helena and Leslie, William D.. (2015). Intervention thresholds and the diagnosis of osteoporosis. Journal of Bone and Mineral Research. 30(10), pp. 1747 - 1753. https://doi.org/10.1002/jbmr.2531
Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool
Javaid, M. K., Kyer, C., Mitchell, P. J., Chana, J., Moss, C., Edwards, M. H., McLellan, A. R., Stenmark, J., Pierroz, D. D., Schneider, M. C., Kanis, John A., Akesson, K. and Cooper, Cyrus. (2015). Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool. Osteoporosis International. 26(11), pp. 2573 - 2578. https://doi.org/10.1007/s00198-015-3192-0
New genetic loci link adipose and insulin biology to body fat distribution
Shungin, Dmitry, Winkler, Thomas W., Croteau-Chonka, Damien C., Ferreira, Teresa, Locke, Adam E., Mägi, Reedik, Strawbridge, Rona J., Pers, Tune H., Fischer, Krista, Justice, Anne E., Workalemahu, Tsegaselassie, Wu, Joseph M. W., Buchkovich, Martin L., Heard-Costa, Nancy L., Roman, Tamara S., Drong, Alexander W., Song, Ci, Gustafsson, Stefan, Day, Felix R., ... Lorentzon, Mattias. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518, pp. 187 - 196. https://doi.org/10.1038/nature14132
Health economic aspects of vertebral augmentation procedures
Borgström, F., Beall, D. P., Berven, S., Boonen, S., Christie, S., Kallmes, D. F., Kanis, John A., Olafsson, G., Singer, A. J. and Åkesson, K.. (2015). Health economic aspects of vertebral augmentation procedures. Osteoporosis International. 26(4), pp. 1239 - 1249. https://doi.org/10.1007/s00198-014-2953-5
Adjusting fracture probability by trabecular bone score
McCloskey, Eugene V., Oden, Anders, Harvey, Nicholas C., Leslie, William D., Hans, Didier, Johansson, Helena and Kanis, John A.. (2015). Adjusting fracture probability by trabecular bone score. Calcified Tissue International. 96(6), pp. 500 - 509. https://doi.org/10.1007/s00223-015-9980-x
Lower urinary symptoms are associated with low levels of serum serotonin, high levels of adinopectin and fasting glucose, and benign prostatic enlargement
Haghsheno, Mohammad-Ali, Mellstrom, Dan, Peeker, Ralph, Hammarsten, Jan, Lorentzon, Mattias, Sundh, Valter, Karlsson, Magnus, Ohlsson, Claes and Damber, Jan-Erik. (2015). Lower urinary symptoms are associated with low levels of serum serotonin, high levels of adinopectin and fasting glucose, and benign prostatic enlargement. Scandinavian Journal of Urology. 49(2), pp. 155 - 161. https://doi.org/10.3109/21681805.2014.936495
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty
Arden, Nigel, Richette, Pascal, Cooper, Cyrus, Bruyère, Olivier, Abadie, Eric, Branco, Jaime, Brandi, Maria Luisa, Berenbaum, Francis, Clerc, Cécile, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, D'Hooghe, Pieter, Herrero-Beaumont, Gabriel, Kanis, John A., Laslop, Andrea, Leblanc, Véronique, Maggi, Stefania, Mautone, Giuseppe, ... Reginster, Jean-Yves. (2015). Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty. Drugs and Aging. 32(7), pp. 525 - 535. https://doi.org/10.1007/s40266-015-0276-7
The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis
Kherad, M., Mellström, Dan, Rosengren, Björn E., Hasserius, R., Nilsson, J.-Å., Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias and Karlsson, Magnus K.. (2015). The number and characteristics of prevalent vertebral fractures in elderly men are associated with low bone mass and osteoporosis. The Bone and Joint Journal. 97-B(8), pp. 1106 - 1110. https://doi.org/10.1302/0301-620X.97B8.35032
Incidence of hip fracture in Brazil and the development of a FRAX model
Zerbini, C. A. F., Szejnfeld, V. L., Abergaria, B. H., McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2015). Incidence of hip fracture in Brazil and the development of a FRAX model. Archives of Osteoporosis. 10(1), pp. 1 - 7. https://doi.org/10.1007/s11657-015-0224-5
A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis
Hiligsmann, Mickaël, Evers, Silvia M., Sedrine, Wafa Ben, Kanis, John A., Ramaekers, Bram, Reginster, Jean Yves, Silverman, S., Wyers, Caroline E. and Boonen, Annelies. (2015). A systematic review of cost-effectiveness analyses of drugs for postmenopausal osteoporosis. PharmacoEconomics. 33(3), pp. 205 - 224. https://doi.org/10.1007/s40273-014-0231-1
Changes in cortical volumetric bone mineral density and thickness, and trabecular thickness in lactating women postpartum
Brembeck, P., Lorentzon, Mattias, Ohlsson, Claes, Winkvist, A. and Augustin, H.. (2015). Changes in cortical volumetric bone mineral density and thickness, and trabecular thickness in lactating women postpartum. The Journal of Clinical Endocrinology and Metabolism. 100(2), pp. 535 - 543. https://doi.org/10.1210/jc.2014-2825
Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement
Reginster, Jean Yves, Reiter-Niesert, S., Bruyère, O., Berenbaum, F., Brandi, Maria-Luisa, Branco, J., Devogelaer, J.-P., Herrero-Beaumont, G., Kanis, John A., Maggi, S., Maheu, E., Richette, P., Rizzoli, R. and Cooper, C.. (2015). Recommendations for an update of the 2010 European regulatory guideline on clinical investigation of medicinal products used in the treatment of osteoarthritis and reflections about related clinically relevant outcomes: Expert consensus statement. Osteoarthritis and Cartilage. 23(12), pp. 2086 - 2093. https://doi.org/10.1016/j.joca.2015.07.001
Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis
McCloskey, Eugene V., Kanis, John A., Oden, Anders, Harvey, Nicholas C., Bauer, D., Gonzalez-Macias, J., Hans, D., Kaptoge, S., Krieg, Marc Antoine, Kwok, T., Marin, F., Moayyeri, A., Orwoll, E., Gluёr, C. and Johansson, Helena. (2015). Predictive ability of heel quantitative ultrasound for incident fractures: an individual-level meta-analysis. Osteoporosis International. 26(7), pp. 1979 - 1987. https://doi.org/10.1007/s00198-015-3072-7
FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK
McCloskey, Eugene V., Kanis, John A., Johansson, Helena, Harvey, Nicholas C., Oden, Anders, Cooper, Alun, Cooper, C., Francis, Roger M., Reid, D. M., Marsh, D., Selby, P., Thompson, F., Hewitt, S. and Compston, Juliet E.. (2015). FRAX-based assessment and intervention thresholds - An exploration of thresholds in women aged 50 years and older in the UK. Osteoporosis International. 26(8), pp. 2091 - 2099. https://doi.org/10.1007/s00198-015-3176-0
FRAX and the effect of teriparatide on vertebral and non-vertebral fracture
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Burge, R., Mitlak, B., Johansson, Helena and McCloskey, Eugene V.. (2015). FRAX and the effect of teriparatide on vertebral and non-vertebral fracture. Osteoporosis International. 26(11), pp. 2677 - 2684. https://doi.org/10.1007/s00198-015-3173-3
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
Cornelis, Marilyn C., Byrne, Enda M., Esko, Tonu, Nalls, Michael A., Ganna, Andrea, Paynter, Nina, Monda, Keri L., Amin, Najaf, Fischer, Krista, Renstrom, Frida, Ngwa, Julius S., Huikari, Ville, Cavadino, Alana, Nolte, Ilja M., Teumer, Alexander, Yu, Kai, Marques-Vidal, Pedro Manuel, Rawal, Rajesh, Manichaikul, Ani, ... UK Brain Expression Consortium (UKBEC). (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 20(5), pp. 647-656. https://doi.org/10.1038/mp.2014.107
Low clinical relevance of a prevalent vertebral fracture in elderly men - the MrOs Sweden study
Kherad, Mehrsa, Rosengren, Björn E., Hasserius, Ralph, Nilsson, Jan-Åke, Redlund-Johnell, Inga, Ohlsson, Claes, Lorentzon, Mattias, Mellström, Dan and Karlsson, Magnus K.. (2015). Low clinical relevance of a prevalent vertebral fracture in elderly men - the MrOs Sweden study. The Spine Journal. 15(2), pp. 281 - 289. https://doi.org/10.1016/j.spinee.2014.09.016
Increased cortical porosity in older men with fracture
Sundh, Daniel, Mellström, Dan, Nilsson, Martin, Karlsson, Magnus, Ohlsson, Claes and Lorentzon, Mattias. (2015). Increased cortical porosity in older men with fracture. Journal of Bone and Mineral Research. 30(9), pp. 1692 - 1700. https://doi.org/10.1002/jbmr.2509
The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cianferotti, Luisella, Cricelli, Claudio, Kanis, John A., Nuti, Ranuccio, Reginster, Jean-Yves, Ringe, Johann D., Rizzoli, Rene and Brandi, Maria Luisa. (2015). The clinical use of vitamin D metabolites and their potential developments: A position statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Endocrine. 50(1), pp. 12 - 26. https://doi.org/10.1007/s12020-015-0606-x
Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women
Leslie, William D., Lix, Lisa M., Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2015). Hip axis length is a FRAX-and bone density-independent risk factor for hip fracture in women. The Journal of Clinical Endocrinology and Metabolism. 100(5), pp. 2063 - 2070. https://doi.org/10.1210/jc.2014-4390
Bone turnover markers predict bone mass development in young adult men: A five-year longitudinal study
Darelid, Anna, Nilsson, Martin, Kindblom, Jenny M., Mellström, Dan, Ohlsson, Claes and Lorentzon, Mattias. (2015). Bone turnover markers predict bone mass development in young adult men: A five-year longitudinal study. The Journal of Clinical Endocrinology and Metabolism. 100(4), pp. 1460 - 1468. https://doi.org/10.1210/jc.2014-3947
Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older
Bischoff-Ferrari, Heike A., Orav, J. E., Kanis, John A., Rizzoli, R., Schlögl, M., Staehelin, H. B., Willett, Walter C. and Dawson-Hughes, B.. (2015). Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Osteoporosis International. 26(12), pp. 2793 - 2802. https://doi.org/10.1007/s00198-015-3194-y
High serum adiponectin is associated with low blood haemoglobin in elderly men: The Swedish MrOS study
Lewerin, C., Johansson, Helena, Lerner, Ulf H., Karlsson, Magnus K., Lorentzon, Mattias, Barrett-Connor, Elizabeth, Smith, Ulf, Ohlsson, Claes and Mellström, Dan. (2015). High serum adiponectin is associated with low blood haemoglobin in elderly men: The Swedish MrOS study. Journal of Internal Medicine. 278(1), pp. 68 - 76. https://doi.org/10.1111/joim.12340
Is the Swedish FRAX model appropriate for Swedish immigrants?
Johansson, Helena, Oden, Anders, Lorentzon, Mattias, McCloskey, Eugene V., Kanis, John A., Harvey, Nicholas C., Karlsson, M. K. and Mellström, Dan. (2015). Is the Swedish FRAX model appropriate for Swedish immigrants? Osteoporosis International. 26(11), pp. 2617 - 2622. https://doi.org/10.1007/s00198-015-3180-4
Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis
Bruyère, Olivier, Cooper, Cyrus, Arden, Nigel, Branco, Jaime, Brandi, Maria Luisa, Herrero-Beaumont, Gabriel, Berenbaum, Francis, Dennison, Elaine M., Devogelaer, Jean-Pierre, Hochberg, Marc, Kanis, John A., Laslop, Andrea, McAlindon, Tim, Reiter, Susanne, Richette, Pascal, Rizzoli, Rene and Reginster, Jean-Yves. (2015). Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis. Drugs and Aging. 32(3), pp. 179 - 187. https://doi.org/10.1007/s40266-015-0243-3
Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX
Harvey, Nicholas C., Kanis, John A., Oden, Anders, Nakamura, T., Shiraki, M., Sugimoto, T., Kuroda, T., Johansson, Helena and McCloskey, Eugene V.. (2015). Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX. Osteoporosis International. 26(9), pp. 2347 - 2353. https://doi.org/10.1007/s00198-015-3129-7
FRAX and fracture prediction without bone mineral density
Kanis, John A., Harvey, Nicholas C., Johansson, Helena, Oden, Anders, Leslie, William D. and McCloskey, Eugene. (2015). FRAX and fracture prediction without bone mineral density. Climacteric. 18, pp. 2 - 9. https://doi.org/10.3109/13697137.2015.1092342
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index
Hoggart, Clive J., Venturini, Giulia, Mangino, Massimo, Gomez, Felicia, Ascari, Giulia, Zhao, Jing Hua, Teumer, Alexander, Winkler, Thomas W., Tšernikova, Natalia, Luan, Jian'an, Mihailov, Evelin, Ehret, Georg B., Zhang, Weihua, Lamparter, David, Esko, Tõnu, Macé, Aurelien, Rüeger, Sina, Bochud, Pierre-Yves, Barcella, Matteo, ... Lorentzon, Mattias*. (2014). Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genetics. 10(7), p. e1004508. https://doi.org/10.1371/journal.pgen.1004508
Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study
Vimaleswaran, Karani S., Cavadino, Alana, Berry, Diane J., Jorde, Rolf, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J. Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A., Nolte, Ilja M., Houston, Denise K., Ahluwalia, Tarunveer Singh, van der Most, Peter J., Pasko, Dorota, Zgaga, Lina, ... Hyppönen, Elina. (2014). Association of vitamin D status with arterial blood pressure and hypertension risk: A mendelian randomisation study. The Lancet Diabetes & Endocrinology. 2(9), pp. 719 - 729. https://doi.org/10.1016/S2213-8587(14)70113-5
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX
Siggeirsdottir, K., Aspelund, T., Johansson, Helena, Gudmundsson, E. F., Mogensen, B., Jonsson, B. Y., Gudnason, V., McCloskey, Eugene, Oden, Anders, Sigurdsson, G. and Kanis, John A.. (2014). The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX. Osteoporosis International. 25(10), pp. 2445 - 2451. https://doi.org/10.1007/s00198-014-2777-3
Epidemiology and economic burden of osteoporosis in Switzerland
Svedbom, A., Ivergard, M., Hernlund, E., Rizzoli, R. and Kanis, John A.. (2014). Epidemiology and economic burden of osteoporosis in Switzerland. Archives of Osteoporosis. 9, pp. 187 - 187. https://doi.org/10.1007/s11657-014-0187-y
Exercise during growth and young adulthood is independently associated with cortical bone size and strength in old Swedish men
Nilsson, Martin, Sundh, Daniel, Ohlsson, Claes, Karlsson, Magnus, Mellström, Dan and Lorentzon, Mattias. (2014). Exercise during growth and young adulthood is independently associated with cortical bone size and strength in old Swedish men. Journal of Bone and Mineral Research. 29(8), pp. 1795 - 1804. https://doi.org/10.1002/jbmr.2212
Management of osteoporosis of the oldest old
Rizzoli, R, Branco, J., Brandi, Maria Luisa, Boonen, S., Bruyère, O., Cacoub, P., Cooper, Cyrus, Diez-Perez, A, Duder, J., Fielding, R. A., Harvey, Nicholas C., Hiligsmann, Mickaël, Kanis, John A., Petermans, J., Ringe, J. D., Tsouderos, Y., Weinman, J. and Reginster, Jean Yves. (2014). Management of osteoporosis of the oldest old. Osteoporosis International. 25(11), pp. 2507 - 2529. https://doi.org/10.1007/s00198-014-2755-9
Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures
Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2014). Mild morphometric vertebral fractures predict vertebral fractures but not non-vertebral fractures. Osteoporosis International. 25(1), pp. 235 - 241. https://doi.org/10.1007/s00198-013-2460-0
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, Andrew R., Esko, Tonu, Yang, Jian, Vedantam, Sailaya, Pers, Tune H., Gustafsson, Stefan, Chu, Audrey Y., Estrada, Karol, Luan, Jian'an, Kutalik, Zoltán, Amin, Najaf, Buchkovich, Martin L., Croteau-Chonka, Damien C., Day, Felix R., Duan, Yanan, Fall, Tove, Fehrmann, Rudolf, Ferreira, Teresa, Jackson, Anne U., ... Lorentzon, Mattias. (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46(11), pp. 1173 - 1186. https://doi.org/10.1038/ng.3097
Lumbar spine texture enhances 10-year fracture probability assessment
Leslie, William D., Johansson, Helena, Kanis, John A., Lamy, Olivier, Oden, Anders, McCloskey, Eugene V. and Hans, D.. (2014). Lumbar spine texture enhances 10-year fracture probability assessment. Osteoporosis International. 25(9), pp. 2271 - 2277. https://doi.org/10.1007/s00198-014-2761-y
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean Pierre, Raynauld, J. P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean Yves. (2014). Value of biomarkers in osteoarthritis: Current status and perspectives. Postgraduate Medical Journal. 90(1061), pp. 171 - 178. https://doi.org/10.1136/postgradmedj-2013-203726rep
A meta-analysis of reference markers of bone turnover for prediction of fracture
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Morris, Howard A., Cooper, Cyrus and Vasikaran, Samuel. (2014). A meta-analysis of reference markers of bone turnover for prediction of fracture. Calcified Tissue International. 94(5), pp. 560 - 567. https://doi.org/10.1007/s00223-014-9842-y
Serum estradiol levels are inversely associated with cortical porosity in older men
Vandenput, Liesbeth, Lorentzon, Mattias, Sundh, Daniel, Nilsson, Maria E., Karlsson, Magnus K., Mellström, Dan and Ohlsson, Claes. (2014). Serum estradiol levels are inversely associated with cortical porosity in older men. The Journal of Clinical Endocrinology and Metabolism. 99(7), pp. E1322 - E1326. https://doi.org/10.1210/jc.2014-1319
International and ethnic variability of falls in older men
Karlsson, Magnus L., Ribom, Eva L., Nilsson, J.-Å., Karlsson, Caroline, Cöster, Maria, Vonschewelov, Thord, Mallmin, Hans, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Lorentzon, Mattias, Leung, Ping C., Lau, Edith, Cauley, Jane A., Barrett-Connor, Elizabeth, Stefanick, Marcia L., Orwoll, Eric and Rosengren, Björn E.. (2014). International and ethnic variability of falls in older men. Scandinavian Journal of Public Health. 42(2), pp. 194 - 200. https://doi.org/10.1177/1403494813510789
Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE)
Sund, Reijo, Honkanen, Risto, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John and Kröger, Heikki. (2014). Evaluation of the FRAX model for hip fracture predictions in the population-based Kuopio Osteoporosis Risk Factor and Prevention study (OSTPRE). Calcified Tissue International. 95(1), pp. 39 - 45. https://doi.org/10.1007/s00223-014-9860-9
Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region
Wu, Chih-Hsing, McCloskey, Eugene V., Lee, Joon Kiong, Itabashi, Akira, Prince, Richard L., Yu, Wei, Li-Yu, Julie, Chionh, Siok Bee, Zhao, Yanling, Shin, Chan Soo, Gunawan, Tirtarahardja, Tsai, Keh-Sung, Chieng, Poon-Ung, Changlai, Sheng-Pin, Chan, Ding-Cheng, Chen, Jung-Fu, Tanner, S. Bobo, Hans, Didier B., Kanis, John A., ... Yang, Rong-Sen. (2014). Consensus of official position of IOF/ISCD FRAX initiatives in Asia-Pacific Region. Journal of Clinical Densitometry. 17(1), pp. 150 - 155. https://doi.org/10.1016/j.jocd.2013.06.002
The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, Rene, Stevenson, John C., Bauer, Jürgen M., Van Loon, Lucas J.C., Walrand, Stéphane, Kanis, John A., Cooper, Cyrus, Brandi, Maria Luisa, Diez-Perez, Adolfo and Reginster, Jean Yves. (2014). The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas. 79(1), pp. 122 - 132. https://doi.org/10.1016/j.maturitas.2014.07.005
An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Bruyère, Olivier, Cooper, Cyrus, Pelletier, Jean-Pierre, Branco, Jaime, Brandi, Maria Luisa, Guillemin, Francis, Hochberg, Marc C., Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Rizzoli, Rene, Silverman, Stuart and Reginster, Jean-Yves. (2014). An algorithm recommendation for the management of knee osteoarthritis in Europe and internationally: A report from a task force of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 253 - 263. https://doi.org/10.1016/j.semarthrit.2014.05.014
The application of health technology assessment in osteoporosis
Kanis, John A. and Hiligsmann, Mickaël. (2014). The application of health technology assessment in osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 28(6), pp. 895 - 910. https://doi.org/10.1016/j.beem.2014.04.001
Goal-directed treatment of osteoporosis in Europe
Kanis, John A., McCloskey, Eugene, Branco, J., Brandi, Maria-Luisa, Dennison, Elaine M., Devogelaer, J.-P., Ferrari, S., Kaufman, J.-M., Papapoulos, S., Reginster, Jean-Yves and Rizzoli, R.. (2014). Goal-directed treatment of osteoporosis in Europe. Osteoporosis International. 25(11), pp. 2533 - 2543. https://doi.org/10.1007/s00198-014-2787-1
Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Karlsson, Magnus, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellström, Dan. (2014). Waning predictive value of serum adiponectin for fracture risk in elderly men: MrOS Sweden. Osteoporosis International. 25(7), pp. 1831 - 1836. https://doi.org/10.1007/s00198-014-2654-0
Challenges for the development of bone-forming agents in Europe
Kanis, John A., Rizzoli, Rene, Cooper, Cyrus and Reginster, Jean-Yves. (2014). Challenges for the development of bone-forming agents in Europe. Calcified Tissue International. 94(5), pp. 469 - 473. https://doi.org/10.1007/s00223-014-9844-9
Serum estradiol associates with blood hemoglobin in elderly men: The MrOS Sweden study
Lewerin, Catharina, Nilsson-Ehle, Herman, Jacobsson, Stefan, Johansson, Helena, Sundh, Valter, Karlsson, Magnus K., Lorentzon, Mattias, Barrett-Connor, Elizabeth, Vandenput, Liesbeth, Ohlsson, Claes and Mellström, Dan. (2014). Serum estradiol associates with blood hemoglobin in elderly men: The MrOS Sweden study. The Journal of Clinical Endocrinology and Metabolism. 99(7), pp. 2549 - 2556. https://doi.org/10.1210/jc.2013-4111
Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden
Lewerin, C. Lewerin, Nilsson-Ehle, H., Jacobsson, S., Johansson, Helena, Sundh, V., Karlsson, Magnus, Ljunggren, Östen, Lorentzon, Mattias, Kanis, John A., Lerner, Ulf H., Cummings, Steven R., Ohlsson, Claes and Mellström, Dan. (2014). Low holotranscobalamin and cobalamins predict incident fractures in elderly men: The MrOS Sweden. Osteoporosis International. 25(1), pp. 131 - 140. https://doi.org/10.1007/s00198-013-2527-y
A meta-analysis of the association of fracture risk and body mass index in women
Johansson, Helena, Kanis, John A., Oden, Anders, McCloskey, Eugene, Chapurlat, Roland D., Christiansen, Claus, Cummings, Steven R., Diez-Perez, A, Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, D., Khaw, Kay Tee, Krieg, Marc Antoine, Kröger, Heikki, LaCroix, A. Z., Lau, E., Leslie, William D., ... Zillikens, M. Carola. (2014). A meta-analysis of the association of fracture risk and body mass index in women. Journal of Bone and Mineral Research. 29(1), pp. 223 - 233. https://doi.org/10.1002/jbmr.2017
A 6-year exercise program improves skeletal traits without affecting fracture risk: A prospective controlled study in 2621 children
Detter, Fredrik, Rosengren, Björn E., Dencker, Magnus, Lorentzon, Mattias, Nilsson, Jan‐Åke and Karlsson, Magnus K.. (2014). A 6-year exercise program improves skeletal traits without affecting fracture risk: A prospective controlled study in 2621 children. Journal of Bone and Mineral Research. 29(6), pp. 1325 - 1336. https://doi.org/10.1002/jbmr.2168
The effect of latitude on the risk and seasonal variation in hip fracture in Sweden
Oden, Anders, Kanis, John A., McCloskey, Eugene V. and Johansson, Helena. (2014). The effect of latitude on the risk and seasonal variation in hip fracture in Sweden. Journal of Bone and Mineral Research. 29(10), pp. 2217 - 2223. https://doi.org/10.1002/jbmr.2250
A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Guillemin, Francis, Hochberg, Marc C., Tugwell, Peter, Arden, Nigel, Berenbaum, Francis, Boers, Maarten, Boonen, Annelies, Branco, Jaime C., Maria-Luisa, Brandi, Bruyère, Olivier, Gasparik, Andrea Ildiko, Kanis, John A., Kvien, Tore K., Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Pinedo-Villanueva, Rafael, Pinto, Daniel, ... Reginster, Jean-Yves. (2014). A reference case for economic evaluations in osteoarthritis: An expert consensus article from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 44(3), pp. 271 - 282. https://doi.org/10.1016/j.semarthrit.2014.06.005
Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm
Kim, K., Svedbom, A., Luo, X., Sutradhar, S. and Kanis, John A.. (2014). Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm. Osteoporosis International. 25(1), pp. 325 - 337. https://doi.org/10.1007/s00198-013-2521-4
Worldwide uptake of FRAX
Kanis, John A., Johansson, Helena, Oden, Anders, Cooper, Cyrus, McCloskey, Eugene E. V., Epidemiology and Quality of Life Working Group of IOF, and Epidemiology and Quality of Life Working Group of IOF. (2014). Worldwide uptake of FRAX. Archives of Osteoporosis. 9(1), pp. 1 - 10. https://doi.org/10.1007/s11657-013-0166-8
Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type i collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT
Kemp, John P., Sayers, Adrian, Paternoster, Lavinia, Evans, David M., Deere, Kevin, St. Pourcain, Beate, Timpson, Nicholas J., Ring, Susan M., Lorentzon, Mattias, Lehtimäki, Terho, Eriksson, Joel, Kähönen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievänen, Harri, Viikari, Jorma, Lyytikäinen, Leo-Pekka, Smith, George Davey, Fraser, William D., ... Tobias, Jon H.. (2014). Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type i collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT. Journal of Bone and Mineral Research. 29(4), pp. 1015 - 1024. https://doi.org/10.1002/jbmr.2093
Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture
Leslie, William D., Orwoll, E., Nielson, Carrie M., Morin, Suzanne N., Majumdar, S. R., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014). Estimated lean mass and fat mass differentially affect femoral bone density and strength index but are not frax independent risk factors for fracture. Journal of Bone and Mineral Research. 29(S1), pp. 2511 - 2519. https://doi.org/10.1002/jbmr.2280
Gaucher disease and bone manifestations
Marcucci, Gemma, Zimran, Ari, Bembi, Bruno, Kanis, John, Reginster, Jean-Yves, Rizzoli, Rene, Cooper, Cyrus and Brandi, Maria Luisa. (2014). Gaucher disease and bone manifestations. Calcified Tissue International. 95(6), pp. 477 - 494. https://doi.org/10.1007/s00223-014-9923-y
Trabecular bone score: A noninvasive analytical method based upon the DXA image
Silva, Barbara C., Leslie, William D., Resch, Heinrich, Lamy, Olivier, Lesnyak, Olga, Binkley, Neil, McCloskey, Eugene V., Kanis, John A. and Bilezikian, John P.. (2014). Trabecular bone score: A noninvasive analytical method based upon the DXA image. Journal of Bone and Mineral Research. 29(3), pp. 518 - 530. https://doi.org/10.1002/jbmr.2176
Can change in FRAX score be used to "treat to target"? A population-based cohort study
Leslie, William D., Majumdar, S. R., Lix, Lisa, Morin, Suzanne N., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2014). Can change in FRAX score be used to "treat to target"? A population-based cohort study. Journal of Bone and Mineral Research. 29(5), pp. 1074 - 1080. https://doi.org/10.1002/jbmr.2151
Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels
Kwan, Johnny S. H., Hsu, Yi-Hsiang, Cheung, Ching-Lung, Dupuis, Josée, Saint-Pierre, Aude, Eriksson, Joel, Handelman, Samuel K., Aragaki, Aaron K., Karasik, David, Pramstaller, Peter P., Kooperberg, Charles, Lacroix, Andrea Z., Larson, Martin G., Lau, Kam-Shing, Lorentzon, Mattias, Pichler, Irene, Sham, Pak Chung, Taliun, Daniel, Vandenput, Liesbeth, ... Kung, Annie Wai Chee. (2014). Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Human Molecular Genetics. 23(24), pp. 6684 - 6693. https://doi.org/10.1093/hmg/ddu386
Meta-analysis of gene-level associations for rare variants based on single-variant statistics
Hu, Yi-Juan, Berndt, Sonja, Gustafsson, Stefan, Ganna, Andrea, Hirschhorn, Joel, North, Kari, Ingelsson, Erik, Lin, Dan-Yu, Lorentzon, Karl Mattias and al, et. (2013). Meta-analysis of gene-level associations for rare variants based on single-variant statistics. American Journal of Human Genetics. 93(2), pp. 236-248. https://doi.org/10.1016/j.ajhg.2013.06.011
Causal relationship between obesity and vitamin d status : Bi-directional mendelian randomization analysis of multiple cohorts
Vimaleswaran, Karani, Berry, Diane, Lu, Chen, Tikkanen, E., Pilz, Stefan, Hiraki, Linda, Cooper, Jason, Dastani, Zari, Li, Rui, Houston, Denise, Wood, Andrew, Michaelsson, Karl, Vandenput, Liesbeth, Lorentzon, Karl Mattias, Zgaga, Lina, Yerges-Armstrong, Laura, McCarthy, Mark I., Dupuis, Josee, Kaakinen, Marika, ... al, et. (2013). Causal relationship between obesity and vitamin d status : Bi-directional mendelian randomization analysis of multiple cohorts. PLoS Medicine. 10(2), pp. 1-13. https://doi.org/10.1371/journal.pmed.1001383
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
Randall, J., Winkler, T.W., Kutalik, Z., Berndt, S.I., Jackson, Anne, Monda, K.L., Kilpelainen, Tuomas, Esko, Tonu, Magi, Reedik, Li, Shengxu, Workalemahu, T., Feitosa, Mary, Croteau-Chonka, D.C., Lorentzon, Karl Mattias, Day, Felix, Fall, Tove, Ferreira, Teresa, Gustafsson, Stefan, Locke, A.E., ... al, et. (2013). Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genetics. 9(6), pp. 1-19. https://doi.org/10.1371/journal.pgen.1003500
Intervention thresholds for osteoporosis
Kanis, J. A.. (2013). Intervention thresholds for osteoporosis. In In Genazzani, A. R. (Ed.). Postmenopausal osteoporosis : Hormones and other therapies pp. 145-150 CRC Press.
X-ray-verified fractures are associated with finite element analysis-derived bone strength and trabecular microstructure in young adult men
Rudäng, Robert, Darelid, Anna, Nilsson, Martin, Mellström, Dan, Ohlsson, Claes and Lorentzon, Mattias. (2013). X-ray-verified fractures are associated with finite element analysis-derived bone strength and trabecular microstructure in young adult men. Journal of Bone and Mineral Research. 28(11), pp. 2305-2316. https://doi.org/10.1002/jbmr.1974
Sport-specific association between exercise loading and the density, geometry, and microstructure of weight-bearing bone in young adult men
Nilsson, M., Ohlsson, C., Mellström, D. and Lorentzon, M.. (2013). Sport-specific association between exercise loading and the density, geometry, and microstructure of weight-bearing bone in young adult men. Osteoporosis International. 24(5), pp. 1613-1622. https://doi.org/10.1007/s00198-012-2142-3
Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density of forearm
Zheng, Hou-Feng, Duncan, Emma L., Yerges-Armstrong, Laura M., Eriksson, Joel, Bergström, Ulrica, Leo, Paul J., Leslie, William D., Goltzman, David, Blangero, John, Hanley, David A., Carless, Melanie A., Streeten, Elizabeth A., Lorentzon, Mattias, Brown, Matthew A., Spector, Tim D., Pettersson-Kymmer, Ulrika, Ohlsson, Claes, Mitchell, Braxton D. and Richards, J. Brent. (2013). Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density of forearm. Journal of Medical Genetics. 50(7), pp. 473-478. https://doi.org/10.1136/jmedgenet-2012-101287
Low 25-OH vitamin d is associated with benign prostatic hyperplasia
Haghsheno, Mohammad-Ali, Mellström, Dan, Behre, Carl-Johan, Damber, Jan-Erik, Johansson, Helena, Karlsson, Magnus, Lorentzon, Mattias, Peeker, Ralph, Barret-Connor, Elisabet, Waern, Ewa, Sundh, Valter, Ohlsson, Claes and Hammarsten, Jan. (2013). Low 25-OH vitamin d is associated with benign prostatic hyperplasia. 190(2), pp. 608-614. https://doi.org/10.1016/j.juro.2013.01.104
Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes
Klingberg, Eva, Lorentzon, Mattias, Göthlin, Jan, Mellström, Dan, Geijer, Mats, Ohlsson, Claes, Atkinson, Elizabeth J., Khosla, Sundeep, Carlsten, Hans and Forsblad-d’Elia, Helena. (2013). Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes. Arthritis Research and Therapy. 15, pp. 1-11. https://doi.org/10.1186/ar4368
Updated fracture incidence rates for the Italian version of FRAX®
Piscitelli, P., Chitano, G., Johannson, Henning R., Brandi, Maria Luisa, Kanis, John A. and Black, Deborah. (2013). Updated fracture incidence rates for the Italian version of FRAX®. Osteoporosis International. 24(3), pp. 859 - 866. https://doi.org/10.1007/s00198-012-2021-y
Treatment of osteoporosis in men
Kaufman, J-M, Reginster, J-Y, Boonen, S., Brandi, M. L., Cooper, Cyrus, Dere, W., Devogelaer, J. P., Diez-Perez, A, Kanis, John A., McCloskey, Eugene, Mitlak, B., Orwoll, E, Ringe, J. D., Weryha, G. and Rizzoli, R. (2013). Treatment of osteoporosis in men. Bone. 53(1), pp. 134 - 144. https://doi.org/10.1016/j.bone.2012.11.018
Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model
Jaller, J. J., Jaller, J. J., Lechuga, J. A., Navarro, E., Johansson, Helena and Kanis, John. (2013). Incidence of hip fracture in Barranquilla, Colombia, and the development of a Colombian FRAX model. Calcified Tissue International. 93(1), pp. 15 - 22. https://doi.org/10.1007/s00223-013-9717-7
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure
Paternoster, Lavinia, Lorentzon, Mattias, Lehtimäki, Terho, Eriksson, Joel, Kähönen, Mika, Raitakari, Olli, Laaksonen, Marika, Sievänen, Harri, Viikari, Jorma, Lyytikäinen, Leo-Pekka, Mellström, Dan, Karlsson, Magnus, Ljunggren, Östen, Grundberg, Elin, Kemp, John P., Sayers, Adrian, Nethander, Maria, Evans, David M., Vandenput, Liesbeth, ... Ohlsson, Claes. (2013). Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. PLoS Genetics. 9(2), pp. 1 - 15. https://doi.org/10.1371/journal.pgen.1003247
Value of biomarkers in osteoarthritis: Current status and perspectives
Lotz, M., Martel-Pelletier, Johanne, Christiansen, Claus, Brandi, Maria-Luisa, Bruyère, O., Chapurlat, Roland D., Collette, J., Cooper, Cyrus, Giacovelli, G., Kanis, John A., Karsdal, M. A., Kraus, V., Lems, Willem F., Meulenbelt, I., Pelletier, Jean-Pierre, Raynauld, J.-P., Reiter-Niesert, S., Rizzoli, R., Sandell, L. J., ... Reginster, Jean-Yves. (2013). Value of biomarkers in osteoarthritis: Current status and perspectives. Annals of the Rheumatic Diseases. 72(11), pp. 1756 - 1763. https://doi.org/10.1136/annrheumdis-2013-203726
Quality of life in sarcopenia and frailty
Rizzoli, Rene, Reginster, Jean-Yves, Arnal, Jean-Francois, Bautmans, Ivan, Beaudart, Charlotte, Bischoff-Ferrari, Heike, Biver, Emmanuel, Boonen, Steven, Brandi, Maria-Luisa, Chines, Arkadi, Cooper, Cyrus, Epstein, Sol, Fielding, Roger A., Goodpaster, Bret, Kanis, John A., Kaufman, J., Laslop, A., Malafarina, Vincenzo, Mañas, Leocadio Rodriguez, ... Bruyère, O.. (2013). Quality of life in sarcopenia and frailty. Calcified Tissue International. 93(2), pp. 101 - 120. https://doi.org/10.1007/s00223-013-9758-y
Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Rizzoli, R., Boonen, S., Brandi, Maria-Luisa, Bruyère, O., Cooper, Cyrus, Kanis, John A., Kaufman, J.-M., Ringe, J. D., Weryha, G. and Reginster, Jean Yves. (2013). Vitamin D supplementation in elderly or postmenopausal women: A 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Current Medical Research and Opinion. 29(4), pp. 305 - 313. https://doi.org/10.1185/03007995.2013.766162
Incidence of hip fracture in Romania and the development of a Romanian FRAX model
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013). Incidence of hip fracture in Romania and the development of a Romanian FRAX model. Calcified Tissue International. 92(5), pp. 429 - 436. https://doi.org/10.1007/s00223-013-9697-7
Assessing the impact of osteoporosis on the burden of hip fractures
Oden, Anders, McCloskey, Eugene V., Johansson, Helena and Kanis, John A.. (2013). Assessing the impact of osteoporosis on the burden of hip fractures. Calcified Tissue International. 92(1), pp. 42 - 49. https://doi.org/10.1007/s00223-012-9666-6
Health technology assessment in osteoporosis
Hiligsmann, Mickaël, Kanis, John A., Compston, Juliet, Cooper, Cyrus, Flamion, Bruno, Bergmann, Pierre, Body, Jean-Jaques, Boonen, Steven, Bruyère, Olivier, Devogelaer, Jean-Pierre, Goemaere, Stefan, Kaufman, Jean-Marc, Rozenberg, Serge and Reginster, Jean-Yves. (2013). Health technology assessment in osteoporosis. Calcified Tissue International. 93(1), pp. 1 - 14. https://doi.org/10.1007/s00223-013-9724-8
FRAX-based intervention and assessment thresholds for osteoporosis in Romania
Grigorie, Daniel, Sucaliuc, Alina, Johansson, Helena, Kanis, John A. and McCloskey, Eugene. (2013). FRAX-based intervention and assessment thresholds for osteoporosis in Romania. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 5. https://doi.org/10.1007/s11657-013-0164-x
Selection of women aged 50-64yr for bone density measurement
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2013). Selection of women aged 50-64yr for bone density measurement. Journal of Clinical Densitometry. 16(4), pp. 570 - 578. https://doi.org/10.1016/j.jocd.2013.01.004
Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Hiligsmann, Mickaël, Cooper, Cyrus, Arden, Nigel, Boers, Maarten, Branco, Jaime C., Brandi, Maria Luisa, Bruyère, Olivier, Guillemin, Francis, Hochberg, Marc C., Hunter, David J., Kanis, John A., Kvien, Tore K., Laslop, Andrea, Pelletier, Jean-Pierre, Pinto, Daniel, Reiter-Niesert, Susanne, Rizzoli, Rene, Rovati, Lucio C., Severens, Johan L., ... Reginster, Jean-Yves. (2013). Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Seminars in Arthritis and Rheumatism. 43(3), pp. 303 - 313. https://doi.org/10.1016/j.semarthrit.2013.07.003
Osteoporosis in the European Union: A compendium of country-specific reports
Svedbom, A., Hernlund, E., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt, Kanis, John A., The EU review panel of the IOF, and The EU review panel of the IOF. (2013). Osteoporosis in the European Union: A compendium of country-specific reports. Archives of Osteoporosis. 8(1-2), pp. 1 - 218. https://doi.org/10.1007/s11657-013-0137-0
How to define responders in osteoarthritis
Cooper, Cyrus, Adachi, Jonathan D., Bardin, Thomas, Berenbaum, Francis, Flamion, Bruno, Jonsson, Helgi, Kanis, John A., Pelousse, Franz, Lems, Willem F., Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Reiter, Susanne, Reginster, Jean-Yves, Rizzoli, Rene and Bruyère, Olivier. (2013). How to define responders in osteoarthritis. Current Medical Research and Opinion. 29(6), pp. 719 - 729. https://doi.org/10.1185/03007995.2013.792793
The osteoporosis treatment gap in Romania
Kanis, John, Hernlund, E., Svedbom, Axel, Ivergãrd, M. and Grigorie, Daniel. (2013). The osteoporosis treatment gap in Romania. Acta Endocrinologica. 9(4), pp. 509 - 514. https://doi.org/10.4183/aeb.2013.509
European guidance for the diagnosis and management of osteoporosis in postmenopausal women
Kanis, John A., McCloskey, Eugene V., Johansson, Helena, Cooper, Cyrus, Rizzoli, R. and Reginster, Jean Yves. (2013). European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 24(1), pp. 23 - 57. https://doi.org/10.1007/s00198-012-2074-y
Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis
Ström, O., Jönsson, Bengt and Kanis, John A.. (2013). Intervention thresholds for denosumab in the UK using a FRAX®-based cost-effectiveness analysis. Osteoporosis International. 24(4), pp. 1491 - 1502. https://doi.org/10.1007/s00198-012-2115-6
Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee
Dempster, David W., Compston, Juliet E., Drezner, Marc K., Glorieux, Francis H., Kanis, John A., Malluche, Hartmut, Meunier, Pierre J., Ott, Susan M., Recker, Robert R. and Parfitt, A. Michael. (2013). Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee. Journal of Bone and Mineral Research. 28(1), pp. 2 - 17. https://doi.org/10.1002/jbmr.1805
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Berndt, Sonja I., Gustafsson, Stefan, Mägi, Reedik, Ganna, Andrea, Wheeler, Eleanor, Feitosa, Mary F., Justice, Anne E., Monda, Keri L., Croteau-Chonka, Damien C., Day, Felix R., Esko, Tonu, Fall, Tove, Ferreira, Teresa, Gentilini, Davide, Jackson, Anne U., Luan, Jianan, Randall, Joshua C., Vedantam, Sailaja, Willer, Cristen J., ... Lorentzon, Mattias. (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics. 45, pp. 501 - 512. https://doi.org/10.1038/ng.2606
SCOPE: A scorecard for osteoporosis in Europe
Kanis, John A., Borgström, F., Compston, Juliet E., Dreinhöfer, K., Nolte, E., Jonsson, L., Le, Willem F., McCloskey, Eugene, Rizzoli, R. and Stenmark, J.. (2013). SCOPE: A scorecard for osteoporosis in Europe. Archives of Osteoporosis. 8(42767), pp. 1 - 63. https://doi.org/10.1007/s11657-013-0144-1
Inflammatory bowel disease and the risk of fracture after controlling for FRAX
Targownik, Laura E., Bernstein, Charles N., Nugent, Zoann, Johansson, Helena, Oden, Anders, McCloskey, Eugene, Kanis, John A. and Leslie, William D.. (2013). Inflammatory bowel disease and the risk of fracture after controlling for FRAX. Journal of Bone and Mineral Research. 28(5), pp. 1007 - 1013. https://doi.org/10.1002/jbmr.1848
Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA
Hernlund, E., Svedbom, A., Ivergård, M., Compston, Juliet E., Cooper, Cyrus, Stenmark, J., McCloskey, Eugene V., Jönsson, Bengt and Kanis, John A.. (2013). Osteoporosis in the European Union: Medical management, epidemiology and economic burden: A report prepared in collaboration with the International Osteoporosis Foundation IOF and the European Federation of Pharmaceutical Industry Associations EFPIA. Archives of Osteoporosis. 8(1-2), pp. 1 - 115. https://doi.org/10.1007/s11657-013-0136-1
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
Hoed, Marcel den, Eijgelsheim, Mark, Esko, Tonu, Brundel, Bianca J.J.M., Peal, David S., Evans, David M., Nolte, Ilja M., Segrè, Ayellet V., Hólm, Hilma, Handsaker, Robert E., Westra, Harm-Jan, Johnson, Toby, Isaacs, Aaron, Yang, Jian, Lundby, Alicia, Zhao, Jing Hua, Kim, Young Jin, Go, Min Jin, Almgren, Peter, ... Lorentzon, Mattias. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45(6), pp. 621 - 631. https://doi.org/10.1038/ng.2610
Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF
Kanis, John A., Adachi, Jonathan D., Cooper, Cyrus, Clark, P., Cummings, Steven R., Diaz-Curiel, M., Harvey, Nicholas C., Hiligsmann, Mickaël, Papaioannou, A., Pierroz, D. D., Silverman, S. L. and Szulc, P.. (2013). Standardising the descriptive epidemiology of osteoporosis: Recommendations from the Epidemiology and Quality of Life Working Group of IOF. Osteoporosis International. 24(11), pp. 2763 - 2764. https://doi.org/10.1007/s00198-013-2413-7
Development and application of FRAX in the management of osteoporosis in Ireland
McGowan, B., Kanis, John A., Johansson, Helena, Silke, C. and Whelan, B.. (2013). Development and application of FRAX in the management of osteoporosis in Ireland. Archives of Osteoporosis. 8(2017-02-01), pp. 1 - 6. https://doi.org/10.1007/s11657-013-0146-z
What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis?
Pelletier, Jean Pierre, Cooper, Cyrus, Peterfy, C., Reginster, Jean Yves, Brandi, Maria Luisa, Bruyère, O., Chapurlat, Roland D., Cicuttini, Flavia, Conaghan, P. G., Doherty, M., Genant, H., Giacovelli, G., Hochberg, Marc, Hunter, David J., Kanis, John A., Kloppenburg, M., Laredo, J. D., McAlindon, T., Nevitt, M., ... Guermazi, A.. (2013). What is the predictive value of MRI for the occurrence of knee replacement surgery in knee osteoarthritis? Annals of the Rheumatic Diseases. 72(10), pp. 1594 - 1604. https://doi.org/10.1136/annrheumdis-2013-203631
Assessment of gene-by-sex interaction effect on bone mineral density
Liu, Ching-Ti, Estrada, Karol, Yerges-Armstrong, Laura, Amin, Najaf, Evangelou, Evangelos, Li, Guo, Minster, Ryan L., Carless, Melanie, Kammerer, Candace M., Oei, Ling, Zhou, Yanhua, Alonso, Nerea, Vandenput, Liesbeth, Lorentzon, Karl Mattias, Dailiana, Zoe, Eriksson, Joel, Garcia-Giralt, Natalia, Giroux, Sylvie, Husted, Lise Bjerre, ... al, et. (2012). Assessment of gene-by-sex interaction effect on bone mineral density. Journal of Bone and Mineral Research. 27(10), pp. 2051-2064. https://doi.org/10.1002/jbmr.1679
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in sex steroid hormone regulation
Coviello, A.D., Haring, Robin, Wellons, Melissa, Vaidya, Dhananjay, Lehtimaki, Terho, Keildson, S., Lunetta, Kathryn, He, Chunyan, Fornage, Myriam, Lagou, Vasiliki, Mangino, Massimo, Onland-Moret, N. Charlotte, Vandenput, Liesbeth, Lorentzon, Karl Mattias and et. al.. (2012). A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in sex steroid hormone regulation. PLoS Genetics. 8(7), pp. 1-12. https://doi.org/10.1371/journal.pgen.1002805
A global representation of vitamin D status in healthy populations
Wahl, D. A., Cooper, C., Ebeling, P. R., Eggersdorfer, M., Hilger, J., Hoffmann, K., Josse, R., Kanis, J. A., Mithal, A., Pierroz, D. D., Stenmark, J., Stöcklin, E. and Dawson-Hughes, B.. (2012). A global representation of vitamin D status in healthy populations. Archives of Osteoporosis. 7(1), pp. 155-172. https://doi.org/10.1007/s11657-012-0093-0
Vertebral fractures in ankylosing spondylitis are associated with lower bone mineral density in both central and peripheral skeleton
Klingberg, Eva, Geijer, Mats, Göthlin, Jan, Mellström, Dan, Lorentzon, Mattias, Hilme, Elisabet, Hedberg, Martin, Carlsten, Hans and Forsblad-d'Elia, Helena. (2012). Vertebral fractures in ankylosing spondylitis are associated with lower bone mineral density in both central and peripheral skeleton. The Journal of Rheumatology. 39(10), pp. 1987-1995. https://doi.org/10.3899/jrheum.120316
Smoking is associated with impaired bone mass development in young adult men : A 5-year longitudinal study
Rudäng, Robert, Darelid, Anna, Nilsson, Martin, Nilsson, Staffan, Mellström, Dan, Ohlsson, Claes and Lorentzon, Mattias. (2012). Smoking is associated with impaired bone mass development in young adult men : A 5-year longitudinal study. Journal of Bone and Mineral Research. 27(10), pp. 2189-2197. https://doi.org/10.1002/jbmr.1674
Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment
Klingberg, Eva, Lorentzon, Mattias, Mellström, Dan, Geijer, Mats, Göthlin, Jan, Hilme, Elisabet, Hedberg, Martin, Carlsten, Hans and Forsblad-d'Elia, Helena. (2012). Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment. Arthritis Research and Therapy. 14(3), pp. 1-12. https://doi.org/10.1186/ar3833
Inferior physical performance tests in 10,998 men in the MrOS study is associated with recurrent falls
Karlsson, Magnus K., Ribom, Eva, Nilsson, Jan-Åke, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Lorentzon, Mattiaz, Mallmin, Hans, Stefanick, Marcia, Lapidus, Jodi, Leung, Ping Chung, Kwok, Anthony, Barrett-Connor, Elizabeth, Orwoll, Eric and Rosengren, Björn E.. (2012). Inferior physical performance tests in 10,998 men in the MrOS study is associated with recurrent falls. Age and Ageing. 41(6), pp. 740-746. https://doi.org/10.1093/ageing/afs104
Inferior physical performance test results of 10,998 men in the MrOS Study is associated with high fracture risk
Rosengren, Björn E., Ribom, Eva L., Nilsson, Jan-Åke, Mallmin, Hans, Ljunggren, Östen, Ohlsson, Claes, Mellström, Dan, Lorentzon, Mattias, Stefanick, Marcia, Lapidus, Jodi, Leung, Ping Chung, Kwok, Anthony, Barrett-Connor, Elizabeth, Orwoll, Eric and Karlsson, Magnus K.. (2012). Inferior physical performance test results of 10,998 men in the MrOS Study is associated with high fracture risk. Age and Ageing. 41(3), pp. 339-344. https://doi.org/10.1093/ageing/afs010
Increased physical activity is associated with enhanced development of peak bone mass in men : A five-year longitudinal study
Nilsson, Martin, Ohlsson, Claes, Odén, Anders, Mellström, Dan and Lorentzon, Mattias. (2012). Increased physical activity is associated with enhanced development of peak bone mass in men : A five-year longitudinal study. Journal of Bone and Mineral Research. 27(5), pp. 1206-1214. https://doi.org/10.1002/jbmr.1549
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L., Ntzani, Evangelia E., Oei, Ling, Albagha, Omar M. E., Amin, Najaf, Kemp, John P., Koller, Daniel L., Li, Guo, Liu, Ching-Ti, Minster, Ryan L., Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M., ... Rivadeneira, Fernando. (2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics. 44(5), pp. 491-503. https://doi.org/10.1038/ng.2249
Catch up in bone acquisition in young adult men with late normal puberty
Darelid, Anna, Ohlsson, Claes, Nilsson, Martin, Kindblom, Jenny M., Dan Mellström and Lorentzon, Mattias. (2012). Catch up in bone acquisition in young adult men with late normal puberty. Journal of Bone and Mineral Research. 27(10), pp. 2198-2207. https://doi.org/10.1002/jbmr.1675
Age at adiposity rebound is associated with fat mass in young adult males - The GOOD Study
Ohlsson, Claes, Lorentzon, Mattias, Norjavaara, Ensio and Kindblom, Jenny M.. (2012). Age at adiposity rebound is associated with fat mass in young adult males - The GOOD Study. PLoS ONE. 7(11), pp. 1-8. https://doi.org/10.1371/journal.pone.0049404
Advancing maternal age is associated with lower bone mineral density in young adult male offspring
Rudäng, R., Mellström, D., Clark, E., Ohlsson, C. and Lorentzon, M.. (2012). Advancing maternal age is associated with lower bone mineral density in young adult male offspring. Osteoporosis International. 23, pp. 475-482. https://doi.org/10.1007/s00198-011-1558-5
Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Rizzoli, R, Coxam, V., Avouac, B., Chevalier, T., Fabien-Soulé, V., Kanis, John A., Kaufman, J.-M., Tsouderos, Y. and Reginster, Jean-Yves. (2012). Assessment of health claims in the field of bone: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 23(1), pp. 193 - 199. https://doi.org/10.1007/s00198-011-1561-x
Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model
Stepan, Jan J., Vaculik, Jan, Pavelka, Karel, Zofka, Jan, Johansson, Helena and Kanis, John A.. (2012). Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model. Calcified Tissue International. 90(5), pp. 365 - 372. https://doi.org/10.1007/s00223-012-9582-9
Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper
Goldhahn, J., Féron, J. M., Kanis, J., Papapoulos, S., Reginster, J-Y., Rizzoli, R., Dere, W., Mitlak, B., Tsouderos, Y. and Boonen, S.. (2012). Implications for fracture healing of current and new osteoporosis treatments: An ESCEO consensus paper. Calcified Tissue International. 90(5), pp. 343 - 353. https://doi.org/10.1007/s00223-012-9587-4
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk
Zheng, Hou-Feng, Tobias, Jon H., Duncan, Emma, Evans, David M., Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M., Lehtimäki, Terho, Bergström, Ulrica, Kähönen, Mika, Leo, Paul J., Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C., Viikari, Jorma, Ladouceur, Martin, Lehtimäki, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, ... Lorentzon, Mattias. (2012). WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genetics. 8(7), pp. 1 - 13. https://doi.org/10.1371/journal.pgen.1002745
A systematic review of hip fracture incidence and probability of fracture worldwide
Kanis, John A., Oden, Anders, McCloskey, Eugene V., Johansson, Helena, Wahl, D. A. and Cooper, Cyrus. (2012). A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporosis International. 23(9), pp. 2239 - 2256. https://doi.org/10.1007/s00198-012-1964-3
Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena Johansson, Oden, Anders, Kanis, John A., McCloskey, Eugene, Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus, Thorsby, P. M., Tivesten, A., Barrett-Connor, Elizabeth, Ohlsson, Claes and Mellström, Dan. (2012). Low serum vitamin D is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 23(3), pp. 991 - 999. https://doi.org/10.1007/s00198-011-1809-5
Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)
Cooper, Cyrus, Reginster, Jean-Yves, Cortet, B., Diaz-Curiel, M., Lorenc, R. S., Kanis, John A. and Rizzoli, R.. (2012). Long-term treatment of osteoporosis in postmenopausal women: A review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF). Current Medical Research and Opinion. 28(3), pp. 475 - 491. https://doi.org/10.1185/03007995.2012.663750
Does osteoporosis therapy invalidate FRAX for fracture prediction?
Leslie, William D., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). Does osteoporosis therapy invalidate FRAX for fracture prediction? Journal of Bone and Mineral Research. 27(6), pp. 1243 - 1251. https://doi.org/10.1002/jbmr.1582
Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland
Lippuner, K., Johansson, Helena, Borgström, F., Kanis, John A. and Rizzoli, R.. (2012). Cost-effective intervention thresholds against osteoporotic fractures based on FRAX® in Switzerland. Osteoporosis International. 23(11), pp. 2579 - 2589. https://doi.org/10.1007/s00198-011-1869-6
Antidepressant medications and osteoporosis
Rizzoli, R., Cooper, C., Reginster, Jean Yves, Abrahamsen, Bo, Adachi, Jonathan, Brandi, Maria Luisa, Bruyère, O., Compston, Juliet E., Ducy, P., Ferrari, S., Harvey, Nicholas C., Kanis, John A., Karsenty, G., Laslop, A., Rabenda, V. and Vestergaard, P.. (2012). Antidepressant medications and osteoporosis. Bone. 51(3), pp. 606 - 613. https://doi.org/10.1016/j.bone.2012.05.018
Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model
Cawston, H., Maravic, M., Fardellone, P., Gauthier, A., Kanis, John A., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012). Epidemiological burden of postmenopausal osteoporosis in France from 2010 to 2020: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 237 - 246. https://doi.org/10.1007/s11657-012-0102-3
A comparative study of using non-hip bone density inputs with FRAX®
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). A comparative study of using non-hip bone density inputs with FRAX®. Osteoporosis International. 23(3), pp. 853 - 860. https://doi.org/10.1007/s00198-011-1814-8
Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Senocak, M., Johansson, Helena and Kanis, John A.. (2012). Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study. Osteoporosis International. 23(3), pp. 949 - 955. https://doi.org/10.1007/s00198-011-1655-5
High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden
Johansson, Helena, Oden, Anders, Lerner, Ulf H., Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Karlsson, Magnus, Ljunggren, Östen, Smith, Ulf, McCloskey, Eugene, Kanis, John A., Ohlsson, Claes and Mellstrom, Dan. (2012). High serum adiponectin predicts incident fractures in elderly men: Osteoporotic fractures in men (MrOS) Sweden. Journal of Bone and Mineral Research. 27(6), pp. 1390 - 1396. https://doi.org/10.1002/jbmr.1591
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
Lim, Stephen S., Vos, Theo, Flaxman, Abraham D., Danaei, Goodarz, Shibuya, Kenji, Adair-Rohani, Heather, AlMazroa, Mohammad A., Amann, Markus, Anderson, H. Ross, Andrews, Kathryn G., Aryee, Martin, Atkinson, Charles, Bacchus, Loraine J., Bahalim, Adil N., Balakrishnan, Kalpana, Balmes, John, Barker-Collo, Suzanne, Baxter, Amanda, Bell, Michelle L., ... Ezzati, Majid. (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 380, pp. 2224 - 2260. https://doi.org/10.1016/S0140-6736(12)61766-8
Fracture risk assessment without bone density measurement in routine clinical practice
Leslie, William D., Morin, Suzanne N., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). Fracture risk assessment without bone density measurement in routine clinical practice. Osteoporosis International. 23(1), pp. 75 - 85. https://doi.org/10.1007/s00198-011-1747-2
A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J. P., Boonen, S., Borgström, F., Cooper, Cyrus, Diez-Perez, A., Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012). A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. Osteoporosis International. 23(9), pp. 2257 - 2276. https://doi.org/10.1007/s00198-012-1958-1
FRAX® with and without bone mineral density
Kanis, John A., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Leslie, William D.. (2012). FRAX® with and without bone mineral density. Calcified Tissue International. 90(1), pp. 1 - 13. https://doi.org/10.1007/s00223-011-9544-7
Epidemiology of fracture in the Russian Federation and the development of a FRAX model
Lesnyak, Olga, Ershova, Olga, Belova, Ksenia, Gladkova, Elena, Sinitsina, Olga, Ganert, Olga, Romanova, Marina, Khodirev, Vitalij, Johansson, Helena, McCloskey, Eugene and Kanis, John A.. (2012). Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Archives of Osteoporosis. 7(2017-02-01), pp. 67 - 73. https://doi.org/10.1007/s11657-012-0082-3
Pitfalls in the external validation of FRAX
Kanis, John A., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2012). Pitfalls in the external validation of FRAX. Osteoporosis International. 23(2), pp. 423 - 431. https://doi.org/10.1007/s00198-011-1846-0
Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Dreinhöfer, K., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2012). Burden of postmenopausal osteoporosis in Germany: Estimations from a disease model. Archives of Osteoporosis. 7(2017-02-01), pp. 209 - 218. https://doi.org/10.1007/s11657-012-0099-7
High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice
Leslie, William D., Majumdar, S. R., Lix, Lisa M., Johansson, Helena, Oden, Anders, McCloskey, Eugene V. and Kanis, John A.. (2012). High fracture probability with FRAX® usually indicates densitometric osteoporosis: Implications for clinical practice. Osteoporosis International. 23(1), pp. 391 - 397. https://doi.org/10.1007/s00198-011-1592-3
Potential extensions of the US FRAX algorithm
Melton, Lisa Joseph, Atkinson, Elizabeth J., Achenbach, Sara J., Kanis, John A., Therneau, Terry M., Johansson, Helena, Khosla, Sundeep and Amin, Shreyasee. (2012). Potential extensions of the US FRAX algorithm. Journal of Osteoporosis. 2012, pp. 1 - 8. https://doi.org/10.1155/2012/528790
A reappraisal of generic bisphosphonates in osteoporosis
Kanis, John A., Reginster, Jean Yves, Kaufman, J.-M., Ringe, J.-D., Adachi, Jonathan D., Hiligsmann, Mickaël, Rizzoli, R. and Cooper, Cyrus. (2012). A reappraisal of generic bisphosphonates in osteoporosis. Osteoporosis International. 23(1), pp. 213 - 221. https://doi.org/10.1007/s00198-011-1796-6
FRAX underestimates fracture risk in patients with diabetes
Giangregorio, Lora M., Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2012). FRAX underestimates fracture risk in patients with diabetes. Journal of Bone and Mineral Research. 27(2), pp. 301 - 308. https://doi.org/10.1002/jbmr.556
FRAX® probabilities and risk of major osteoporotic fracture in France
Couris, C. M., Chapurlat, Roland D., Kanis, John A., Johansson, Helena, Burlet, N., Delmas, P. D. and Schott, A. M.. (2012). FRAX® probabilities and risk of major osteoporotic fracture in France. Osteoporosis International. 23(9), pp. 2321 - 2327. https://doi.org/10.1007/s00198-011-1883-8
The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Johansson, Helena, McCloskey, Eugene, Kanis, John A., Turkish Osteoporosis Society, and Turkish Osteoporosis Society. (2012). The impact of a FRAX-based intervention threshold in Turkey: The FRAX-TURK study. Archives of Osteoporosis. 7(2017-02-01), pp. 229 - 235. https://doi.org/10.1007/s11657-012-0101-4
Type 2 diabetes and bone
Leslie, William D., Rubin, Mishaela R., Schwartz, Ann V. and Kanis, John A.. (2012). Type 2 diabetes and bone. Journal of Bone and Mineral Research. 27(11), pp. 2231 - 2237. https://doi.org/10.1002/jbmr.1759
FRAX updates 2012
McCloskey, Eugene V. and Kanis, John A.. (2012). FRAX updates 2012. Current Opinion in Rheumatology. 24(5), pp. 554 - 560. https://doi.org/10.1097/BOR.0b013e328356d2f5
A comparison of case-finding strategies in the UK for the management of hip fractures
Johansson, Helena, Kanis, John A., Oden, Anders, Compston, Juliet E. and McCloskey, Eugene. (2012). A comparison of case-finding strategies in the UK for the management of hip fractures. Osteoporosis International. 23(3), pp. 907 - 915. https://doi.org/10.1007/s00198-011-1864-y
The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa. (2012). The potential impact of the National Osteoporosis Foundation guidance on treatment eligibility in the USA: An update in NHANES 2005-2008. Osteoporosis International. 23(3), pp. 811 - 820. https://doi.org/10.1007/s00198-011-1694-y
Fracture risk assessment
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2012). Fracture risk assessment. Clinical Biochemistry. 45(12), pp. 887 - 893. https://doi.org/10.1016/j.clinbiochem.2012.05.001
An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis
Lekamwasam, S., Adachi, Jonathan D., Agnusdei, D., Bilezikian, J P., Boonen, S., Borgström, F., Cooper, Cyrus, Perez, A. Diez, Eastell, Richard, Hofbauer, L. C., Kanis, John A., Langdahl, B. L., Lesnyak, Olga, Lorenc, R. S., McCloskey, Eugene, Messina, O. D., Napoli, N., Obermayer-Pietsch, B., Ralston, Stuart H., ... Compston, Juliet E.. (2012). An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis. Archives of Osteoporosis. 7(2017-02-01), pp. 25 - 30. https://doi.org/10.1007/s11657-012-0070-7
Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Austin, Matthew S., Siris, E. S., Wang, Andrea, Lewiecki, E. Michael, Lorenc, R. S., Libanati, Cesar and Kanis, John A.. (2012). Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX. Journal of Bone and Mineral Research. 27(7), pp. 1480 - 1486. https://doi.org/10.1002/jbmr.1606
The distribution of FRAX®-based probabilities in women from Japan
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2012). The distribution of FRAX®-based probabilities in women from Japan. Journal of Bone and Mineral Metabolism. 30(6), pp. 700 - 705. https://doi.org/10.1007/s00774-012-0371-3
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
Medina-Gomez, Carolina, Kemp, John P., Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M., Heppe, Denise H. M., Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Zillikens, M. Carola, Olstad, Ole K., Zheng, Hou-Feng, Richards, J. Brent, St. Pourcain, Beate, Hofman, Albert, ... Rivadeneira, Fernando. (2012). Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genetics. 8(7), pp. 1 - 14. https://doi.org/10.1371/journal.pgen.1002718
A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study
Shepstone, L., Fordham, R., Lenaghan, E., Harvey, I., Cooper, Cyrus, Gittoes, Neil, Heawood, A., Peters, T. J., O¿Neill, T. W., Torgerson, David, Holland, R., Howe, A., Marshall, T., Kanis, John A. and McCloskey, Eugene. (2012). A pragmatic randomised controlled trial of the effectiveness and cost-effectiveness of screening older women for the prevention of fractures: Rationale, design and methods for the SCOOP study. Osteoporosis International. 23(10), pp. 2507 - 2515. https://doi.org/10.1007/s00198-011-1876-7
Frailty and sarcopenia: Definitions and outcome parameters
Cooper, Cyrus, Dere, W., Evans, William J., Kanis, John A., Rizzoli, R, Sayer, A. A., Sieber, C. C., Kaufman, J, Van Kan, G. Abellan, Boonen, S., Adachi, Jonathan, Mitlak, B., Tsouderos, Y., Rolland, Y. and Reginster, Jean Yves. (2012). Frailty and sarcopenia: Definitions and outcome parameters. Osteoporosis International. 23(7), pp. 1839 - 1848. https://doi.org/10.1007/s00198-012-1913-1
Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures
Lalmohamed, A., Welsing, P. M. J., Lems, Willem F., Jacobs, J. W. G., Kanis, John A., Johansson, Helena, De Boer, A. and De Vries, F.. (2012). Calibration of FRAX ® 3.1 to the Dutch population with data on the epidemiology of hip fractures. Osteoporosis International. 23(3), pp. 861 - 869. https://doi.org/10.1007/s00198-011-1852-2
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Strawbridge, Rona, Dupuis, Josee, Prokopenko, I., Barker, Adam, Ahlqvist, Emma, Rybin, Denis, Petrie, John, Travers, M.E., Bouatia-Naji, N., Dimas, Antigone, Nica, Alexandra, Wheeler, Eleanor, Chen, Han, Voight, Benjamin, Taneera, Jalal, Lorentzon, K. and et. al.. (2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 60(10), pp. 2624-2634. https://doi.org/10.2337/db11-0415
Pubertal timing predicts leg length and childhood body mass index predicts sitting height in young adult men
Lorentzon, Mattias, Norjavaara, Ensio and Kindblom, Jenny M.. (2011). Pubertal timing predicts leg length and childhood body mass index predicts sitting height in young adult men. 158(3), pp. 452-457. https://doi.org/10.1016/j.jpeds.2010.09.009
Cortical consolidation due to increased mineralization and endosteal contraction in young adult men : A five-year longitudinal study
Ohlsson, Claes, Darelid, Anna, Nilsson, Martin, Melin, Johanna, Mellström, Dan and Lorentzon, Mattias. (2011). Cortical consolidation due to increased mineralization and endosteal contraction in young adult men : A five-year longitudinal study. The Journal of Clinical Endocrinology and Metabolism. 96(7), pp. 2262-2269. https://doi.org/10.1210/jc.2010-2751
Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos
Fraser, L.-A., Langsetmo, L., Berger, C., Ioannidis, G., Goltzman, David, Adachi, Jonathan D., Papaioannou, A., Josse, R. G., Kovacs, C. S., Olszynski, W. P., Towheed, T., Hanley, David A., Kaiser, S. M., Prior, J., Jamal, S., Kreiger, N., Brown, J. P., Johansson, Helena, Oden, Anders, ... Leslie, William D.. (2011). Fracture prediction and calibration of a Canadian FRAX® tool: A population-based report from CaMos. Osteoporosis International. 22(3), pp. 829 - 837. https://doi.org/10.1007/s00198-010-1465-1
A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011). A meta-analysis of the effect of strontium ranelate on the risk of vertebral and non-vertebral fracture in postmenopausal osteoporosis and the interaction with FRAX®. Osteoporosis International. 22(8), pp. 2347 - 2355. https://doi.org/10.1007/s00198-010-1474-0
Evaluation of FRAX to characterise fracture risk in Poland
Czerwinski, E., Kanis, John A., Osieleniec, J., Kumorek, A., Milert, A., Johansson, Helena, McCloskey, Eugene V. and Gorkiewicz, M.. (2011). Evaluation of FRAX to characterise fracture risk in Poland. Osteoporosis International. 22(9), pp. 2507 - 2512. https://doi.org/10.1007/s00198-010-1502-0
Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report
Rizzoli, R, Åkesson, K., Bouxsein, M. L., Kanis, John A., Napoli, N., Papapoulos, S., Reginster, Jean Yves and Cooper, Cyrus. (2011). Subtrochanteric fractures after long-term treatment with bisphosphonates: A European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporosis International. 22(2), pp. 373 - 390. https://doi.org/10.1007/s00198-010-1453-5
Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment
Leslie, William D., Lix, Lisa M., Langsetmo, L., Berger, C., Goltzman, David, Hanley, David A., Adachi, J. D., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment. Osteoporosis International. 22(3), pp. 817 - 827. https://doi.org/10.1007/s00198-010-1464-2
Interpretation and use of FRAX in clinical practice
Kanis, John A., Hans, D., Cooper, Cyrus, Baim, Sanford, Bilezikian, J. P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Dawson-Hughes, Bess, Fuleihan, Ghada El-Hajj, Johansson, Helena, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., Oden, Anders, Papapoulos, S., Poiana, Catalina, Rizzoli, R, Wahl, D. A. and McCloskey, Eugene. (2011). Interpretation and use of FRAX in clinical practice. Osteoporosis International. 22(9), pp. 2395 - 2411. https://doi.org/10.1007/s00198-011-1713-z
FRAX - modell för att beräkna 10-årsrisken för fraktur
Johansson, Helena, Kanis, John, Ljunggren, Östen, Ström, O., Svensson, Olle and Mellström, Dan. (2011). FRAX - modell för att beräkna 10-årsrisken för fraktur. Lakartidningen. 108(7), pp. 336 - 339.
Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security
Johansson, Helena, Clark, P., Carlos, F., Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Increasing age- and sex-specific rates of hip fracture in Mexico: A survey of the Mexican institute of social security. Osteoporosis International. 22(8), pp. 2359 - 2364. https://doi.org/10.1007/s00198-010-1475-z
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
Kilpeläinen, Tuomas O., Zillikens, M. Carola, Stančákova, Alena, Finucane, Francis M., Ried, Janina S., Langenberg, Claudia, Zhang, Weihua, Beckmann, Jacques S., Luan, Jian'an, Vandenput, Liesbeth, Styrkarsdottir, Unnur, Zhou, Yanhua, Smith, Albert V., Zhao, Jing-Hua, Amin, Najaf, Vedantam, Sailaja, Shin, So-Youn, Haritunians, Talin, Fu, Mao, ... Loos, Ruth J. F.. (2011). Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nature Genetics. 43(8), pp. 753 - 760. https://doi.org/10.1038/ng.866
Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model
Gauthier, A., Kanis, John A., Jiang, Yling, Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011). Epidemiological burden of postmenopausal osteoporosis in the UK from 2010 to 2021: Estimations from a disease model. Archives of Osteoporosis. 6(2017-02-01), pp. 179 - 188. https://doi.org/10.1007/s11657-011-0063-y
Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice
Hans, Dieder B. L., Kanis, John A., Baim, Sanford, Bilezikian, John P., Binkley, Neil, Cauley, Jane A., Compston, Juliet E., Cooper, Cyrus, Dawson-Hughes, Bess, El-Hajj Fuleihan, Ghada, Leslie, William D., Lewiecki, E. Michael, Luckey, Marjorie M., McCloskey, Eugene V., Papapoulos, Socrates E., Poiana, Catalina and Rizzoli, Rene. (2011). Joint official positions of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. Executive Summary of the 2010 Position Development Conference on Interpretation and Use of FRAX® in Clinical Practice. Journal of Clinical Densitometry. 14(3), pp. 171 - 180. https://doi.org/10.1016/j.jocd.2011.05.007
Development and validation of a disease model for postmenopausal osteoporosis
Gauthier, A., Kanis, John A., Martin, M., Compston, Juliet E., Borgström, F., Cooper, Cyrus and McCloskey, Eugene. (2011). Development and validation of a disease model for postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 771 - 780. https://doi.org/10.1007/s00198-010-1358-3
Partial adherence: A new perspective on health economic assessment in osteoporosis
Kanis, John A., Cooper, Cyrus, Hiligsmann, Mickaël, Rabenda, V., Reginster, Jean-Yves and Rizzoli, R.. (2011). Partial adherence: A new perspective on health economic assessment in osteoporosis. Osteoporosis International. 22(10), pp. 2565 - 2573. https://doi.org/10.1007/s00198-011-1668-0
Genetic determinants of serum testosterone concentrations in men
Ohlsson, Claes, Wallaschofski, Henri, Lunetta, Kathryn L., Stolk, Lisette, Perry, John R. B., Koster, Annemarie, Petersen, Ann-Kristin, Eriksson, Joel, Lehtima¨ki, Terho, Huhtaniemi, Ilpo T., Hammond, Geoffrey L., Maggio, Marcello, Coviello, Andrea D., Ferrucci, Luigi, Heier, Margit, Hofman, Albert, Holliday, Kate L., Jansson, John-Olov, Kahonen, Mika, ... Melzer, David. (2011). Genetic determinants of serum testosterone concentrations in men. PLoS Genetics. 7(10), pp. 1 - 11. https://doi.org/10.1371/journal.pgen.1002313
The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland
Badurski, Janusz E., Kanis, John A., Johansson, Helena, Dobrenko, Andrzej, Nowak, Nonna A., Daniluk, Stefan and Jezienicka, Elzbieta. (2011). The application of FRAX® to determine intervention thresholds in osteoporosis treatment in Poland. Polish Archives of Internal Medicine. 121(5), pp. 148 - 155.
Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis
Jönsson, Bengt, Ström, O., Eisman, John A., Papaioannou, A., Siris, E. S., Tosteson, Anna N. A. and Kanis, John A.. (2011). Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis. Osteoporosis International. 22(3), pp. 967 - 982. https://doi.org/10.1007/s00198-010-1424-x
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms
Zhai, Guangju, Teumer, Alexander, Stolk, Lisette, Perry, John R. B., Vandenput, Liesbeth, Coviello, Andrea D., Koster, Annemarie, Bell, Jordana T., Bhasin, Shalender, Eriksson, Joel, Ernst, Florian, Ferrucci, Luigi, Frayling, Timothy M., Glass, Daniel, Grundberg, Elin, Haring, Robin, Hedman, Åsa K., Hofman, Albert, Kiel, Douglas P., ... MuTHER Consortium. (2011). Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genetics. 7(4), pp. 1 - 10. https://doi.org/10.1371/journal.pgen.1002025
Osteoporosis: Burden, health care provision and opportunities in the EU
Ström, O., Borgström, F., Kanis, John A., Compston, Juliet E., Cooper, Cyrus, McCloskey, Eugene V. and Jönsson, B.. (2011). Osteoporosis: Burden, health care provision and opportunities in the EU. Archives of Osteoporosis. 6(42767), pp. 59 - 155. https://doi.org/10.1007/s11657-011-0060-1
Guidance for the adjustment of FRAX according to the dose of glucocorticoids
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2011). Guidance for the adjustment of FRAX according to the dose of glucocorticoids. Osteoporosis International. 22(3), pp. 809 - 816. https://doi.org/10.1007/s00198-010-1524-7
Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX
Lewiecki, E. Michael, Compston, Juliet E., Miller, Paul D., Adachi, Jonathan D., Adams, Judith E., Leslie, William D., Kanis, John A., Moayyeri, Alireza, Adler, Robert A., Hans, Didier B., Kendler, David L., Diez-Perez, Adolfo, Krieg, Marc-Antoine, Masri, Basel K., Lorenc, Roman R., Bauer, Douglas C., Blake, Glen M., Josse, Robert G., Clark, Patricia and Khan, Aliya A.. (2011). Official positions for FRAX® Bone Mineral Density and FRAX® Simplification. From Joint official positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX. Journal of Clinical Densitometry. 14(3), pp. 226 - 236. https://doi.org/10.1016/j.jocd.2011.05.017
Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis
Rizzoli, Rene, Reginster, Jean-Yves, Boonen, Steven, Bréart, Gérard, Diez-Perez, Adolfo, Felsenberg, Dieter, Kaufman, Jean-Marc, Kanis, John A. and Cooper, Cyrus. (2011). Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis. Calcified Tissue International. 89(2), pp. 91 - 104. https://doi.org/10.1007/s00223-011-9499-8
Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance
Looker, A. C., Dawson-Hughes, B., Tosteson, Anna N. A., Johansson, Helena, Kanis, John A. and Melton, Lisa J.. (2011). Hip fracture risk in older US adults by treatment eligibility status based on new National Osteoporosis Foundation guidance. Osteoporosis International. 22(2), pp. 541 - 549. https://doi.org/10.1007/s00198-010-1288-0
Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John A.. (2011). Spine-hip discordance and fracture risk assessment: A physician-friendly FRAX enhancement. Osteoporosis International. 22(3), pp. 839 - 847. https://doi.org/10.1007/s00198-010-1461-5
Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden
Johansson, Helena, Oden, Anders, Kanis, John A., McCloskey, Eugene V., Lorentzon, Mattias, Ljunggren, Östen, Karlsson, Magnus K., Orwoll, E., Tivesten, A., Ohlsson, Claes and Mellström, Dan. (2011). Low bone mineral density is associated with increased mortality in elderly men: MrOS Sweden. Osteoporosis International. 22(5), pp. 1411 - 1418. https://doi.org/10.1007/s00198-010-1331-1
Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards
Vasikaran, Samuel, Eastell, Richard, Bruyere, O., Foldes, A. J., Garnero, P., Griesmacher, Andrea, McClung, Michael R., Morris, Howard A., Silverman, S., Trenti, Tommaso, Wahl, D. A., Cooper, Cyrus and Kanis, John A.. (2011). Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: A need for international reference standards. Osteoporosis International. 22(2), pp. 391 - 420. https://doi.org/10.1007/s00198-010-1501-1
Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies
Bischoff-Ferrari, Heike A., Dawson-Hughes, Bess, Baron, John A., Kanis, John A., Orav, Endel J., Staehelin, Hannes B., Kiel, Douglas P., Burckhardt, Peter, Henschkowski, Jana, Spiegelman, Donna, Li, Ruifeng, Wong, John B., Feskanich, Diane and Willett, Walter C.. (2011). Milk intake and risk of hip fracture in men and women: A meta-analysis of prospective cohort studies. Journal of Bone and Mineral Research. 26(4), pp. 833 - 839. https://doi.org/10.1002/jbmr.279
Secular trends in the incidence of hip and other osteoporotic fractures
Cooper, Cyrus, Cole, Z. A., Holroyd, C. R., Earl, S. C., Harvey, Nicholas C., Dennison, Elaine M., Melton, Lisa, Cummings, Steven R. and Kanis, John A.. (2011). Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporosis International. 22(5), pp. 1277 - 1288. https://doi.org/10.1007/s00198-011-1601-6
A FRAX® model for the assessment of fracture probability in Belgium
Johansson, Helena, Kanis, John, McCloskey, Eugene, Oden, Anders, Devogelaer, J. P., Kaufman, J-M, Neuprez, A., Hiligsmann, Mickaël, Bruyère, O. and Reginster, Jean Yves. (2011). A FRAX® model for the assessment of fracture probability in Belgium. Osteoporosis International. 22(2), pp. 453-461. https://doi.org/10.1007/s00198-010-1218-1
International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis
Vasikaran, Samuel, Cooper, Cyrus, Eastell, Richard, Griesmacher, Andrea, Morris, Howard A., Trenti, Tommaso and Kanis, John A.. (2011). International osteoporosis foundation and international federation of clinical chemistry and laboratory medicine position on bone marker standards in osteoporosis. Clinical Chemistry and Laboratory Medicine. 49(8), pp. 1271 - 1274. https://doi.org/10.1515/CCLM.2011.602
Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective
Borgström, F., Ström, O., Kleman, M., McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John A.. (2011). Cost-effectiveness of bazedoxifene incorporating the FRAX® algorithm in a European perspective. Osteoporosis International. 22(3), pp. 955 - 965. https://doi.org/10.1007/s00198-010-1291-5
Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer
Ivergãrd, M., Ström, O., Borgström, F., Burge, R., Tosteson, Anna N. A. and Kanis, John. (2010). Identifying cost-effective treatment with raloxifene in postmenopausal women using risk algorithms for fractures and invasive breast cancer. Bone. 47(5), pp. 966 - 974. https://doi.org/10.1016/j.bone.2010.07.024
The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). The cost-effectiveness of strontium ranelate in the UK for the management of osteoporosis. Osteoporosis International. 21(2), pp. 339 - 349. https://doi.org/10.1007/s00198-009-0971-5
Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration
Leslie, William D., Lix, Lisa, Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). Independent clinical validation of a Canadian FRAX tool: Fracture prediction and model calibration. Journal of Bone and Mineral Research. 25(11), pp. 2350 - 2358. https://doi.org/10.1002/jbmr.123
Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer
McCloskey, Eugene, Paterson, Alexander, Kanis, John, Tähtelä, Rita and Powles, Trevor. (2010). Effect of oral clodronate on bone mass, bone turnover and subsequent metastases in women with primary breast cancer. European Journal of Cancer. 46(3), pp. 558 - 565. https://doi.org/10.1016/j.ejca.2009.12.003
FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example
Ström, O., Borgström, F., Kleman, M., McCloskey, Eugene, Oden, Anders, Johansson, Helena and Kanis, John. (2010). FRAX® and its applications in health economics-Cost-effectiveness and intervention thresholds using bazedoxifene in a Swedish setting as an example. Bone. 47(2), pp. 430 - 437. https://doi.org/10.1016/j.bone.2010.05.020
Smoking predicts incident fractures in elderly men: Mr OS Sweden
Jutberger, Hans, Lorentzon, Mattias, Barrett-Connor, Elizabeth, Johansson, Helena, Kanis, John, Ljunggren, Östen, Karlsson, Magnus, Rosengren, Björn E., Redlund-Johnell, Inga, Orwoll, E, Ohlsson, Claes and Mellström, Dan. (2010). Smoking predicts incident fractures in elderly men: Mr OS Sweden. Journal of Bone and Mineral Research. 25(5), pp. 1010 - 1016. https://doi.org/10.1359/jbmr.091112
An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women
Kanis, John, McCloskey, Eugene, Jonsson, Bengt, Cooper, Alun, Ström, O. and Borgström, F.. (2010). An evaluation of the NICE guidance for the prevention of osteoporotic fragility fractures in postmenopausal women. Archives of Osteoporosis. 5(43862), pp. 19 - 48. https://doi.org/10.1007/s11657-010-0045-5
Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study
Berry, S. D., Kiel, Douglas P., Donaldson, Meghan G., Cummings, Steven R., Kanis, John, Johansson, Helena and Samelson, E. J.. (2010). Application of the national osteoporosis foundation guidelines to postmenopausal women and men: The Framingham osteoporosis study. Osteoporosis International. 21(1), pp. 53 - 60. https://doi.org/10.1007/s00198-009-1127-3
The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES)
Bruyère, O., Kanis, John, Ibar-Abadie, M. E., Alsayed, N., Brandi, Maria Luisa, Burlet, N., Cahall, D., Chines, A., Devogelaer, J. P., Dere, W., Goel, N., Hughes, N., Kaufman, J-M, Korte, S., Mitlak, Bruce, Niese, D., Rizzoli, Rene, Rovati, Lucio C. and Reginster, Jean Yves. (2010). The need for a transparent, ethical, and successful relationship between academic scientists and the pharmaceutical industry: A view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporosis International. 21(5), pp. 713 - 722. https://doi.org/10.1007/s00198-010-1190-9
Validation of the IOF quality of life questionnaire for patients with wrist fracture
Lips, P., Jameson, Karen A., Bianchi, Maria L., Goemaere, Stefan, Boonen, Steven, Reeve, Jonathan, Stepan, Jan J., Johnell, O., van Schoor, Natasja M., Dennison, Elaine M., Kanis, John and Cooper, Cyrus. (2010). Validation of the IOF quality of life questionnaire for patients with wrist fracture. Osteoporosis International. 21(1), pp. 61 - 70. https://doi.org/10.1007/s00198-009-0946-6
The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®
Borgström, F., Ström, O., Coelho, J., Johansson, Helena, Oden, Anders, McCloskey, Eugene and Kanis, John. (2010). The cost-effectiveness of risedronate in the UK for the management of osteoporosis using the FRAX®. Osteoporosis International. 21(3), pp. 495 - 505. https://doi.org/10.1007/s00198-009-0989-8
The effects of a FRAX® revision for the USA
Kanis, John, Johansson, Helena, Oden, Anders, Dawson-Hughes, Bess, Melton, Lisa and McCloskey, Eugene. (2010). The effects of a FRAX® revision for the USA. Osteoporosis International. 21(1), pp. 35 - 40. https://doi.org/10.1007/s00198-009-1033-8
FRAX assessment of osteoporotic fracture probability in Switzerland
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2010). FRAX assessment of osteoporotic fracture probability in Switzerland. Osteoporosis International. 21(3), pp. 381 - 389. https://doi.org/10.1007/s00198-009-0975-1
The potential impact of new National Osteoporosis Foundation guidance on treatment patterns
Dawson-Hughes, Bess, Looker, A. C., Tosteson, Anna N. A., Johansson, Helena, Kanis, John and Melton, Lisa. (2010). The potential impact of new National Osteoporosis Foundation guidance on treatment patterns. Osteoporosis International. 21(1), pp. 41 - 52. https://doi.org/10.1007/s00198-009-1034-7
A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®
Kanis, John A., Johansson, Helena, Oden, Anders and McCloskey, Eugene V.. (2010). A meta-analysis of the efficacy of raloxifene on all clinical and vertebral fractures and its dependency on FRAX®. Bone. 47(4), pp. 729-735. https://doi.org/10.1016/j.bone.2010.06.009
The incidence and risk of hip fracture in Poland
Czerwinski, E., Kanis, John, Trybulec, B., Johansson, Helena, Borowy, P. and Osieleniec, J.. (2009). The incidence and risk of hip fracture in Poland. Osteoporosis International. 20(8), pp. 1363 - 1367. https://doi.org/10.1007/s00198-008-0787-8
BMD, clinical risk factors and their combination for hip fracture prevention
Johansson, Helena, Kanis, John, Oden, Anders, Johnell, O. and McCloskey, Eugene. (2009). BMD, clinical risk factors and their combination for hip fracture prevention. Osteoporosis International. 20(10), pp. 1675 - 1682. https://doi.org/10.1007/s00198-009-0845-x
How to decide who to treat
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F. and Oden, Anders. (2009). How to decide who to treat. Best Practice and Research: Clinical Rheumatology. 23(6), pp. 711 - 726. https://doi.org/10.1016/j.berh.2009.09.002
FRAX® and its applications to clinical practice
Kanis, John, Oden, Anders, Johansson, Helena, Borgström, F., Ström, O. and McCloskey, Eugene. (2009). FRAX® and its applications to clinical practice. Bone. 44(5), pp. 734 - 743. https://doi.org/10.1016/j.bone.2009.01.373
Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate
Kayan, K., Johansson, Helena, Oden, Anders, Vasireddy, S., Pande, K., Orgee, J., Kanis, John and McCloskey, Eugene. (2009). Can fall risk be incorporated into fracture risk assessment algorithms: A pilot study of responsiveness to clodronate. Osteoporosis International. 20(12), pp. 2055 - 2061. https://doi.org/10.1007/s00198-009-0942-x
Approaches to the targeting of treatment for osteoporosis.
Kanis, John, McCloskey, Eugene, Johansson, Helena and Oden, Anders. (2009). Approaches to the targeting of treatment for osteoporosis. Nature Reviews Rheumatology. 5(8), pp. 425 - 431. https://doi.org/10.1038/nrrheum.2009.139
Cost-effectiveness of hormone therapy in the United States
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009). Cost-effectiveness of hormone therapy in the United States. Journal of Women's Health. 18(10), pp. 1669 - 1677. https://doi.org/10.1089/jwh.2008.1246
An updated systematic review of health state utility values for osteoporosis related conditions
Peasgood, T., Herrmann, K., Kanis, John and Brazier, J. E.. (2009). An updated systematic review of health state utility values for osteoporosis related conditions. Osteoporosis International. 20(6), pp. 853 - 868. https://doi.org/10.1007/s00198-009-0844-y
Assessment of fracture risk
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009). Assessment of fracture risk. European Journal of Radiology. 71(3), pp. 392 - 397. https://doi.org/10.1007/s11914-011-0093-9
Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women
Lippuner, K., Johansson, Helena, Kanis, John and Rizzoli, Rene. (2009). Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women. Osteoporosis International. 20(7), pp. 1131 - 1140. https://doi.org/10.1007/s00198-008-0779-8
Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study
McCloskey, Eugene, Johansson, Helena, Oden, Anders, Vasireddy, S., Kayan, K., Pande, K., Jalava, T. and Kanis, John. (2009). Ten-year fracture probability identifies women who will benefit from clodronate therapy-additional results from a double-blind, placebo-controlled randomised study. Osteoporosis International. 20(5), pp. 811 - 817. https://doi.org/10.1007/s00198-008-0786-9
Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK
Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Kanis, John, Marsh, D., McCloskey, Eugene, Reid, David M., Selby, P. and Wilkins, M.. (2009). Guidelines for the diagnosis and management of osteoporosis in postmenopausal women and men from the age of 50 years in the UK. Maturitas. 62(2), pp. 105 - 108. https://doi.org/10.1016/j.maturitas.2008.11.022
Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®
Kanis, John, Johansson, Helena, Oden, Anders and McCloskey, Eugene. (2009). Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®. Bone. 44(6), pp. 1049 - 1054. https://doi.org/10.1016/j.bone.2009.02.014
From relative risk to absolute fracture risk calculation: The FRAX algorithm
McCloskey, Eugene, Johansson, Helena, Oden, Anders and Kanis, John. (2009). From relative risk to absolute fracture risk calculation: The FRAX algorithm. Current Osteoporosis Reports. 7(3), pp. 77 - 83. https://doi.org/10.1007/s11914-009-0013-4
Incorporating adherence into health economic modelling of osteoporosis
Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2009). Incorporating adherence into health economic modelling of osteoporosis. Osteoporosis International. 20(1), pp. 23 - 34. https://doi.org/10.1007/s00198-008-0644-9
Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2009). Cost-effectiveness of hormone replacement therapy for menopausal symptoms in the UK. Menopause International. 15(1), pp. 19 - 25. https://doi.org/10.1258/mi.2009.009004
Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores
Tsang, S. W. Y., Kung, Annie Wai Chee, Kanis, John, Johansson, Helena and Oden, Anders. (2009). Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores. Osteoporosis International. 20(11), pp. 1939 - 1945. https://doi.org/10.1007/s00198-009-0906-1
Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women
Hans, Didier, Durosier, Claire, Kanis, John, Johansson, Helena, Schott-Pethelaz, Anne Marie and Krieg, Marc Antoine. (2008). Assessment of the 10-year probability of osteoporotic hip fracture combining clinical risk factors and heel bone ultrasound: The EPISEM prospective cohort of 12,958 elderly women. Journal of Bone and Mineral Research. 23(7), pp. 1045 - 1051. https://doi.org/10.1359/jbmr.080229
Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX)
Fujiwara, S., Nakamura, T., Orimo, H., Hosoi, T., Gorai, I., Oden, Anders, Johansson, Helena and Kanis, John. (2008). Development and application of a Japanese model of the WHO fracture risk assessment tool (FRAX). Osteoporosis International. 19(4), pp. 429 - 435. https://doi.org/10.1007/s00198-007-0544-4
The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden
Zethraeus, N., Ström, O., Borgström, Frederick, Kanis, John and Jönsson, B.. (2008). The cost-effectiveness of the treatment of high risk women with osteoporosis, hypertension and hyperlipidaemia in Sweden. Osteoporosis International. 19(6), pp. 819 - 827. https://doi.org/10.1007/s00198-007-0511-0
A reference standard for the description of osteoporosis
Kanis, John A., McCloskey, Eugene V., Johansson, Helena, Oden, Anders, Melton III, L. Joseph and Khaltaev, Nikolai. (2008). A reference standard for the description of osteoporosis. Bone. 42(3), pp. 467-475. https://doi.org/10.1016/j.bone.2007.11.001
Health economics of osteoporosis
Borgström, F. and Kanis, John. (2008). Health economics of osteoporosis. Best Practice and Research: Clinical Endocrinology and Metabolism. 22(5), pp. 885 - 900. https://doi.org/10.1016/j.beem.2008.07.005
Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis
McCloskey, Eugene, Vasireddy, S., Threlkeld, Jane, Eastaugh, Joanne, Parry, Ailsa, Bonnet, Nicolas, Beneton, Monique, Kanis, John and Charlesworth, Diane. (2008). Vertebral fracture assessment (VPA) with a densitometer predicts future fractures in elderly women unselected for osteoporosis. Journal of Bone and Mineral Research. 23(10), pp. 1561 - 1568. https://doi.org/10.1359/jbmr.080515
Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial
Lekander, I., Borgström, F., Ström, O., Zethraeus, N. and Kanis, John. (2008). Cost effectiveness of hormone therapy in women at high risks of fracture in Sweden, the US and the UK-Results based on the Women's Health Initiative randomised controlled trial. Bone. 42(2), pp. 294 - 306. https://doi.org/10.1016/j.bone.2007.09.059
Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis
Goldhahn, J., Scheele, Wim H., Mitlak, Bruce, Abadie, Eric, Aspenberg, Per, Augat, Peter, Brandi, Maria Luisa, Burlet, N., Chines, A., Delmas, P. D., Dupin-Roger, Isabelle, Ethgen, D., Hanson, Beate, Hartl, Florian, Kanis, John, Kewalramani, Reshma, Laslop, A., Marsh, David, Ormarsdottir, Sif, ... Reginster, Jean Yves. (2008). Clinical evaluation of medicinal products for acceleration of fracture healing in patients with osteoporosis. Bone. 43(2), pp. 343 - 347. https://doi.org/10.1016/j.bone.2008.04.017
FRAX' and the assessment of fracture probability in men and women from the UK
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena and McCloskey, Eugene. (2008). FRAX' and the assessment of fracture probability in men and women from the UK. Osteoporosis International. 19(4), pp. 385 - 397. https://doi.org/10.1007/s00198-007-0543-5
Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK
Kanis, John, McCloskey, Eugene, Johansson, Helena, Ström, O., Borgström, F., Oden, Anders, Compston, Juliet E., Cooper, Alun, Cooper, Cyrus, Francis, Roger M., Marsh, D., Reid, David M., Selby, P. and Wilkins, M.. (2008). Case finding for the management of osteoporosis with FRAX® - Assessment and intervention thresholds for the UK. Osteoporosis International. 19(10), pp. 1395 - 1408. https://doi.org/10.1007/s00198-008-0712-1
Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study
McCloskey, Eugene, Beneton, Monique, Charlesworth, Diane, Kayan, K., DeTakats, Dominic, Dey, Abhijit, Orgee, J., Ashford, Robert, Forster, Martin, Cliffe, Jennifer, Kersh, Linda, Brazier, J. E., Nichol, Jon, Aropuu, Sakari, Jalava, T. and Kanis, John. (2007). Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: Results of a double-blind, placebo-controlled randomized study. Journal of Bone and Mineral Research. 22(1), pp. 135 - 141. https://doi.org/10.1359/jbmr.061008
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women
Kanis, John, Oden, Anders, Johnell, O., Johansson, Helena, Laet, C. De, Brown, Jacques P., Burckhardt, Peter, Cooper, Cyrus, Christiansen, Claus, Cummings, Steven R., Eisman, John A., Fujiwara, S., Glüer, C. C., Goltzman, David, Hans, Didier, Krieg, Marc Antoine, Lacroix, Andrea Z., McCloskey, Eugene, Mellström, Dan, ... Yoshimura, N.. (2007). The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporosis International. 18(8), pp. 1033 - 1046. https://doi.org/10.1007/s00198-007-0343-y
Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis.
Kanis, John, Stevenson, M., McCloskey, Eugene, Davis, S. and Lloyd-Jones, Myfanwy. (2007). Glucocorticoid-induced osteoporosis: a systematic review and cost-utility analysis. Health Technology Assessment. 11(7). https://doi.org/10.3310/hta11070
Adherence to treatment of osteoporosis: A need for study
Lekkerkerker, F., Kanis, John, Alsayed, N., Bouvenot, G., Burlet, N., Cahall, D., Chines, A., Delmas, P. D., Dreiser, R. L., Ethgen, D., Hughes, N., Kaufman, J-M, Korte, S., Kreutz, G., Laslop, A., Mitlak, Bruce, Rabenda, V., Rizzoli, Rene, Santora, Arthur C., ... Reginster, Jean Yves. (2007). Adherence to treatment of osteoporosis: A need for study. Osteoporosis International. 18(10), pp. 1311 - 1317. https://doi.org/10.1007/s00198-007-0410-4
The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks
van Staa, T. P., Kanis, John, Geusens, P., Boonen, Annelies, Leufkens, H. G. M. and Cooper, Cyrus. (2007). The cost-effectiveness of bisphosphonates in postmenopausal women based on individual long-term fracture risks. Value in Health. 10(5), pp. 348 - 357. https://doi.org/10.1111/j.1524-4733.2007.00188.x
Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007.
Martin, T. John, Christiansen, Claus, Kanis, John and Russell, Graham. (2007). Herbert Andre Fleisch, MD : 22 July 1933-15 May 2007. Osteoporosis International. 18(8), pp. 1019 - 1021. https://doi.org/10.1007/s00198-007-0416-y
Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model
Zethraeus, N., Borgström, F., Ström, O., Kanis, John and Jönsson, B.. (2007). Cost-effectiveness of the treatment and prevention of osteoporosis - A review of the literature and a reference model. Osteoporosis International. 18(1), pp. 9 - 23. https://doi.org/10.1007/s00198-006-0257-0
Latitude, socioeconomic prosperity, mobile phones and hip fracture risk
Johnell, O., Borgström, F., Jönsson, B. and Kanis, John. (2007). Latitude, socioeconomic prosperity, mobile phones and hip fracture risk. Osteoporosis International. 18(3), pp. 333 - 337. https://doi.org/10.1007/s00198-006-0245-4
Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial
Ström, O., Borgström, Frederick, Sen, S. S., Boonen, Steven, Haentjens, P., Johnell, O. and Kanis, John. (2007). Cost-effectiveness of alendronate in the treatment of postmenopausal women in 9 European countries - An economic evaluation based on the fracture intervention trial. Osteoporosis International. 18(8), pp. 1047 - 1061. https://doi.org/10.1007/s00198-007-0349-5
At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis
Borgström, F., Johnell, O., Kanis, John, Jönsson, B. and Rehnberg, C.. (2006). At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis. Osteoporosis International. 17(10), pp. 1459 - 1471. https://doi.org/10.1007/s00198-006-0107-0
Bone fragility in men - Where are we?
Seeman, Ego, Bianchi, Georges, Khosla, Sundeep, Kanis, John and Orwoll, E. (2006). Bone fragility in men - Where are we? Osteoporosis International. 17(11), pp. 1577 - 1583. https://doi.org/10.1007/s00198-006-0160-8
The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective
Borgström, F., Carlsson, Å., Sintonen, H., Boonen, Steven, Haentjens, P., Burge, R., Johnell, O., Jönsson, B. and Kanis, John. (2006). The cost-effectiveness of risedronate in the treatment of osteoporosis: An international perspective. Osteoporosis International. 17(7), pp. 996 - 1007. https://doi.org/10.1007/s00198-006-0094-1
The use of multiple sites for the diagnosis of osteoporosis
Kanis, John, Johnell, O., Oden, Anders, Johansson, Helena, Eisman, John A., Fujiwara, S., Kröger, Heikki, Honkanen, Risto, Melton, Lisa, O'Neill, T. W., Reeve, Jonathan, Silman, A. and Tenenhouse, A.. (2006). The use of multiple sites for the diagnosis of osteoporosis. Osteoporosis International. 17(4), pp. 527 - 534. https://doi.org/10.1007/s00198-005-0014-9
Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
Powles, Trevor, Paterson, Alexander, McCloskey, Eugene, Schein, Phil, Scheffler, Bobbi, Tidy, Alwynne, Ashley, Sue, Smith, Ian, Ottestad, Lars and Kanis, John. (2006). Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Research. 8(2). https://doi.org/10.1186/bcr1384
A simple clinical score for estimating the long-term risk of fracture in post-menopausal women
van Staa, T. P., Geusens, P., Kanis, J. A., Leufkens, H. G. M., Gehlbach, S. and Cooper, C.. (2006). A simple clinical score for estimating the long-term risk of fracture in post-menopausal women. QJM: An International Journal of Medicine. 99(10), pp. 673-682. https://doi.org/10.1093/qjmed/hcl094
An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials
Borgström, F., Jönsson, B., Ström, O. and Kanis, John. (2006). An economic evaluation of strontium ranelate in the treatment of osteoporosis in a Swedish setting: Based on the results of the SOTI and TROPOS trials. Osteoporosis International. 17(12), pp. 1781 - 1793. https://doi.org/10.1007/s00198-006-0193-z
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
Johnell, O. and Kanis, John. (2006). An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporosis International. 17(12), pp. 1726 - 1733. https://doi.org/10.1007/s00198-006-0172-4
Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT
Hordon, L. D., Itoda, M., Shore, P. A., Shore, R. C., Heald, M., Brown, M., Kanis, John, Rodan, G. A. and Aaron, J. E.. (2006). Preservation of thoracic spine microarchitecture by alendronate: Comparison of histology and microCT. Bone. 38(3), pp. 444 - 449. https://doi.org/10.1016/j.bone.2005.09.020