Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers
Journal article
McKay, Alannah K. A., Peeling, Peter, Pyne, David B., Welvaert, Marijke, Tee, Nicolin, Leckey, Jill J., Sharma, Avish P., Ross, Megan L. R., Garvican-Lewis, Laura A., van Swelm, Rachel P. L., Laarakkers, Coby M. and Burke, Louise M.. (2019). Acute carbohydrate ingestion does not influence the post-exercise iron-regulatory response in elite keto-adapted race walkers. Journal of Science and Medicine in Sport. 22(6), pp. 635 - 640. https://doi.org/10.1016/j.jsams.2018.12.015
Authors | McKay, Alannah K. A., Peeling, Peter, Pyne, David B., Welvaert, Marijke, Tee, Nicolin, Leckey, Jill J., Sharma, Avish P., Ross, Megan L. R., Garvican-Lewis, Laura A., van Swelm, Rachel P. L., Laarakkers, Coby M. and Burke, Louise M. |
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Abstract | Objectives Adhering to a low carbohydrate (CHO) high fat (LCHF) diet can alter markers of iron metabolism in endurance athletes. This investigation examined the re-introduction of CHO prior to, and during exercise on the iron-regulatory response to exercise in a homogenous (in regard to serum ferritin concentration) group of athletes adapted to a LCHF diet. Design Parallel groups design. Methods Three weeks prior to the exercise trials, twenty-three elite race walkers adhered to either a CHO-rich (n = 14) or LCHF diet (n = 9). A standardised 19–25 km race walk was performed while athletes were still adhering to their allocated dietary intervention (Adapt). A second test was performed three days later, where all athletes were placed on a high CHO diet (CHO Restoration). Venous blood samples were collected pre-, post- and 3 h post-exercise and measured for interleukin-6 (IL-6) and hepcidin-25. Results The post-exercise IL-6 increase was greater in LCHF (p < 0.001) during both the Adapt (LCHF: 13.1-fold increase; 95% CI: 5.6–23.0, CHO: 8.0-fold increase; 5.1–11.1) and CHO Restoration trials (LCHF: 18.5-fold increase; 10.9–28.9, CHO: 6.3-fold increase; 3.9–9.5); outcomes were not different between trials (p = 0.84). Hepcidin-25 concentrations increased 3 h post-exercise (p < 0.001), however, they did not differ between trials (p = 0.46) or diets (p = 0.84). Conclusions The elevated IL-6 response in athletes adapted to a LCHF diet was not attenuated by an acute increase in exogenous CHO availability. Despite diet-induced differences in IL-6 response to exercise, post-exercise hepcidin levels were similar between diets and trials, indicating CHO availability has minimal influence on post-exercise iron metabolism. |
Keywords | LCHF diet; iron metabolism; ferritin; hepcidin; interleukin-6; race-walkers |
Year | 2019 |
Journal | Journal of Science and Medicine in Sport |
Journal citation | 22 (6), pp. 635 - 640 |
Publisher | Elsevier Australia |
ISSN | 1440-2440 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.jsams.2018.12.015 |
Scopus EID | 2-s2.0-85059539667 |
Page range | 635 - 640 |
Research Group | Mary MacKillop Institute for Health Research |
Publisher's version | File Access Level Controlled |
Place of publication | United Kingdom |
https://acuresearchbank.acu.edu.au/item/881v4/acute-carbohydrate-ingestion-does-not-influence-the-post-exercise-iron-regulatory-response-in-elite-keto-adapted-race-walkers
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